Overview
Background
Dr Mostafa Kamal Masud is a CCQ Next Generation Cancer Research Fellow at the Australian Institute for Bioengineering & Nanotechnology (AIBN), the University of Queensland (UQ). In 2020, he received his PhD in Medical Biotechnology Diagnostics and Nanobiotechnology from AIBN, UQ. He received his MS and B.Sc. (Hons.) in Chemistry from Shahjalal University of Science and Technology (SUST), Sylhet-3114, Bangladesh. After completing his PhD, he was awarded a prestigious JSPS Postdoctoral Fellowship (success rate >10%) from Japan and served as a Postdoctoral Fellow at Japan's National Institute for Materials Science (NIMS).He recently been awarded a highly prestigious ARC DECRA fellowship for the period 2024-2026 and a QLD Cancer Council fellowship for the period 2024–2028. His research focuses on the development of novel nanostructures and nanodiagnostic technologies to address critical issues in medical diagnosis. As an early career researcher, he has an excellent track record with more than 60 peer-reviewed publications in prestigious and high-impact journals in the area that achieve <2800 citations with an h-index of 29 (Scholar google link: https://bit.ly/2Vtv67l). He has developed new classes of superparamagnetic nanostructures and fabricated novel biosensors for the detection of disease-specific biomolecular targets e.g., for miRNA, DNA, exosome and protein biomarker detection that have proven to be easy and effective, allowing for rapid diagnosis with minimal equipment. He made a major contribution to nanotechnology integrated-analytical and diagnostic fields by providing analytical and technological input as well as developing key collaborations with clinicians and biologists for translational research. His strategy is to create nano-architecture point-of-care diagnostic technology for early diagnosis of cancer that could hopefully lead to a healthy and happier life for humans.
Availability
- Dr Mostafa Kamal Masud is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Chemistry, Shahjalal University of Science and Technology
- Masters (Research) of Inorganic Chemistry, Shahjalal University of Science and Technology
- Doctor of Philosophy, The University of Queensland
Research interests
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Nanoarchitectonics
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Medical Diagnostics
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Biosensor
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Nanobiotechnology
Research impacts
Dr Masud pioneered the synthesis of new classes of superparamagnetic nanostructures specific to targeting biomarkers or capturing antibodies. His synthesized nanostructures perform rapid isolation based on simple magnetism and exhibit intrinsic peroxidase activities, substantially replacing the expensive natural enzyme (HRP) in immunoassays and strip-based sensing. These nanostructures are utilized in fabricating novel biosensors for detecting disease-specific biomarkers such as microRNA, autoantibodies, and extracellular vesicles (exosomes). This research has advanced the field from polymer- or centrifuge-based isolation and enzyme-based detection to more efficient and straightforward synthesis of target-specific mesoporous nanostructures, magnetic isolation, and single-step detection.
He also led the development of highly sensitive mesoporous gold (and alloy) transduction surfaces, simplifying the process from complex to single-step. His research characterized biomarkers (exosomal miRNAs), transduction surface interactions, bindings, and sensitive signal generation. He also led the translation of such mesoporous systems into wearable and flexible substrates, demonstrating high neural activity in a mouse model, thereby advancing the field of wearable diagnostics. To translate his research into clinical settings, he has initiated collaborations with clinicians, engineers, and IoT specialists
Works
Search Professor Mostafa Kamal Masud’s works on UQ eSpace
2017
Journal Article
Electrochemical biosensing strategies for DNA methylation analysis
Hossain, Tanvir, Mahmudunnabi, Golam, Masud, Mostafa Kamal, Islam, Md. Nazmul, Ooi, Lezanne, Konstantinov, Konstantin, Al Hossain, Md Shahriar, Martinac, Boris, Alici, Gursel, Nguyen, Nam-Trung and Shiddiky, Muhammad J. A. (2017). Electrochemical biosensing strategies for DNA methylation analysis. Biosensors and Bioelectronics, 94, 63-73. doi: 10.1016/j.bios.2017.02.026
2017
Journal Article
Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA
Masud, Mostafa Kamal, Islam, Md. Nazmul, Haque, Md. Hakimul, Tanaka, Shunsuke, Gopalan, Vinod, Alici, Gursel, Nguyen, Nam-Trung, Lam, Alfred K., Hossain, Md. Shahriar A., Yamauchi, Yusuke and Shiddiky, Muhammad J. A. (2017). Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA. Chemical Communications, 53 (58), 8231-8234. doi: 10.1039/c7cc04789d
2017
Journal Article
Quantification of gene-specific DNA methylation in oesophageal cancer via electrochemistry
Haque, Md. Hakimul, Gopalan, Vinod, Islam, Md. Nazmul, Masud, Mostafa Kamal, Bhattacharjee, Ripon, Al Hossain, Md. Shahriar, Nguyen, Nam-Trung, Lam, Alfred K. and Shiddiky, Muhammad J. A. (2017). Quantification of gene-specific DNA methylation in oesophageal cancer via electrochemistry. Analytica Chimica Acta, 976, 84-93. doi: 10.1016/j.aca.2017.04.034
2017
Journal Article
Gold-loaded nanoporous iron oxide nanocubes: a novel dispersible capture agent for tumor-associated autoantibody analysis in serum
Yadav, Sharda, Masud, Mostafa Kamal, Islam, Md. Nazmul, Gopalan, Vinod, Lam, Alfred King-yin, Tanaka, Shunsuke, Nguyen, Nam-Trung, Al Hossain, Md. Shahriar, Li, Cuiling, Yamauchi, Md. Yusuke and Shiddiky, Muhammad J. A. (2017). Gold-loaded nanoporous iron oxide nanocubes: a novel dispersible capture agent for tumor-associated autoantibody analysis in serum. Nanoscale, 9 (25), 8805-8814. doi: 10.1039/c7nr03006a
2017
Journal Article
RNA biomarkers: diagnostic and prognostic potentials and recent developments of electrochemical biosensors
Islam, Md Nazmul, Masud, Mostafa Kamal, Haque, Md Hakimul, Al Hossain, Md Shahriar, Yamauchi, Yusuke, Nam-Trung Nguyen, and Shiddiky, Muhammad J. A. (2017). RNA biomarkers: diagnostic and prognostic potentials and recent developments of electrochemical biosensors. Small Methods, 1 (7) 1700131, 1700131. doi: 10.1002/smtd.201700131
2016
Journal Article
Synthesis, characterization and catalytic activities of palladium(II) nitroaryl complexes
Huq, Mohammad Maududul, Robiur Rahman, Md., Naher, Masnun, Khan, Mohammad Mizanur Rahman, Masud, Mostafa Kamal, Hossain, Golam Mohammad Golzar, Zhu, Nianyong, Lo, Yih Hsing, Younus, Muhammad and Wong, Wai-Yeung (2016). Synthesis, characterization and catalytic activities of palladium(II) nitroaryl complexes. Journal of Inorganic and Organometallic Polymers and Materials, 26 (6), 1243-1252. doi: 10.1007/s10904-016-0434-3
2016
Journal Article
Synthesis, spectroscopic characterization, thermal and luminescent properties of new organosulfur-functionalized platinum(II) bis(alkenylarylalkynyl) complexes
Rahman, Md. Mostafizur, Younus, Muhammad, Naher, Masnun, Masud, Mostafa Kamal, Nomoto, Akihiro, Ogawa, Akiya, Rudnick, Alexander and Köhler, Anna (2016). Synthesis, spectroscopic characterization, thermal and luminescent properties of new organosulfur-functionalized platinum(II) bis(alkenylarylalkynyl) complexes. Journal of Organometallic Chemistry, 818, 185-194. doi: 10.1016/j.jorganchem.2016.06.006
Supervision
Availability
- Dr Mostafa Kamal Masud is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Nanodiagnostics for early detection and monitoring of ovarian cancer
Principal Advisor
Other advisors: Professor Yusuke Yamauchi, Associate Professor MD Shahriar Hossain
Completed supervision
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2025
Doctor Philosophy
Magnetoplasmonic Nanostructures for the Detection of Clinically Relevant Biomarkers
Associate Advisor
Other advisors: Professor Yusuke Yamauchi, Dr Valentino Kaneti, Associate Professor MD Shahriar Hossain
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2025
Doctor Philosophy
Nanoarchitecture-integrated Iron Oxide-based Platform for Biosensing Applications
Associate Advisor
Other advisors: Professor Carlos Salomon Gallo, Associate Professor MD Shahriar Hossain, Dr Valentino Kaneti, Professor Yusuke Yamauchi
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2024
Doctor Philosophy
Nanoarchitectured Mesoporous Gold-Alloy for microRNA Sensing
Associate Advisor
Other advisors: Professor Carlos Salomon Gallo, Professor Yusuke Yamauchi, Dr Valentino Kaneti, Associate Professor MD Shahriar Hossain
Media
Enquiries
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