
Overview
Background
Dr Mostafa Kamal Masud is a CCQ Next Generation Cancer Research Fellow at the Australian Institute for Bioengineering & Nanotechnology (AIBN), the University of Queensland (UQ). In 2020, he received his PhD in Medical Biotechnology Diagnostics and Nanobiotechnology from AIBN, UQ. He received his MS and B.Sc. (Hons.) in Chemistry from Shahjalal University of Science and Technology (SUST), Sylhet-3114, Bangladesh. After completing his PhD, he was awarded a prestigious JSPS Postdoctoral Fellowship (success rate >10%) from Japan and served as a Postdoctoral Fellow at Japan's National Institute for Materials Science (NIMS).He recently been awarded a highly prestigious ARC DECRA fellowship for the period 2024-2026 and a QLD Cancer Council fellowship for the period 2024–2028. His research focuses on the development of novel nanostructures and nanodiagnostic technologies to address critical issues in medical diagnosis. As an early career researcher, he has an excellent track record with more than 60 peer-reviewed publications in prestigious and high-impact journals in the area that achieve <2800 citations with an h-index of 29 (Scholar google link: https://bit.ly/2Vtv67l). He has developed new classes of superparamagnetic nanostructures and fabricated novel biosensors for the detection of disease-specific biomolecular targets e.g., for miRNA, DNA, exosome and protein biomarker detection that have proven to be easy and effective, allowing for rapid diagnosis with minimal equipment. He made a major contribution to nanotechnology integrated-analytical and diagnostic fields by providing analytical and technological input as well as developing key collaborations with clinicians and biologists for translational research. His strategy is to create nano-architecture point-of-care diagnostic technology for early diagnosis of cancer that could hopefully lead to a healthy and happier life for humans.
Availability
- Dr Mostafa Kamal Masud is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Chemistry, Shahjalal University of Science and Technology
- Masters (Research) of Inorganic Chemistry, Shahjalal University of Science and Technology
- Doctor of Philosophy, The University of Queensland
Research interests
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Nanoarchitectonics
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Medical Diagnostics
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Biosensor
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Nanobiotechnology
Research impacts
Dr Masud pioneered the synthesis of new classes of superparamagnetic nanostructures specific to targeting biomarkers or capturing antibodies. His synthesized nanostructures perform rapid isolation based on simple magnetism and exhibit intrinsic peroxidase activities, substantially replacing the expensive natural enzyme (HRP) in immunoassays and strip-based sensing. These nanostructures are utilized in fabricating novel biosensors for detecting disease-specific biomarkers such as microRNA, autoantibodies, and extracellular vesicles (exosomes). This research has advanced the field from polymer- or centrifuge-based isolation and enzyme-based detection to more efficient and straightforward synthesis of target-specific mesoporous nanostructures, magnetic isolation, and single-step detection.
He also led the development of highly sensitive mesoporous gold (and alloy) transduction surfaces, simplifying the process from complex to single-step. His research characterized biomarkers (exosomal miRNAs), transduction surface interactions, bindings, and sensitive signal generation. He also led the translation of such mesoporous systems into wearable and flexible substrates, demonstrating high neural activity in a mouse model, thereby advancing the field of wearable diagnostics. To translate his research into clinical settings, he has initiated collaborations with clinicians, engineers, and IoT specialists
Works
Search Professor Mostafa Kamal Masud’s works on UQ eSpace
2019
Journal Article
Long-lived, transferred crystalline silicon carbide nanomembranes for implantable flexible electronics
Phan, Hoang-Phuon, Zhong, Yishan, Nguyen, Tuan-Khoa, Park, Yoonseok, Dinh, Toan, Song, Enming, Vadivelu, Raja Kumar, Masud, Mostafa Kamal, Li, Jinghua, Shiddiky, Muhammad J. A., Dao, Dzung, Yamauchi, Yusuke, Rogers, John A. and Nguyen, Nam-Trung (2019). Long-lived, transferred crystalline silicon carbide nanomembranes for implantable flexible electronics. ACS Nano, 13 (10), 11572-11581. doi: 10.1021/acsnano.9b05168
2019
Journal Article
Nanoarchitectured peroxidase-mimetic nanozymes: mesoporous nanocrystalline α- or γ-iron oxide?
Masud, Mostafa Kamal, Kim, Jeonghun, Billah, Md. Motasim, Wood, Kathleen, Shiddiky, Mohammad J. A., Nguyen, Nam-Trung, Parsapur, Rajesh Kumar, Kaneti, Yusuf Valentino, Alshehri, Abdulmohsen Ali, Alghamidi, Yousef Gamaan, Alzahrani, Khalid Ahmed, Adharvanachari, Murugulla, Selvam, Parasuraman, Hossain, Md. Shahriar A. and Yamauchi, Yusuke (2019). Nanoarchitectured peroxidase-mimetic nanozymes: mesoporous nanocrystalline α- or γ-iron oxide?. Journal of Materials Chemistry B, 7 (35), 5412-5422. doi: 10.1039/c9tb00989b
2019
Journal Article
Autoantibodies as diagnostic and prognostic cancer biomarker: detection techniques and approaches
Yadav, Sharda, Kashaninejad, Navid, Masud, Mostafa Kamal, Yamauchi, Yusuke, Nguyen, Nam-Trung and Shiddiky, Muhammad J. A. (2019). Autoantibodies as diagnostic and prognostic cancer biomarker: detection techniques and approaches. Biosensors and Bioelectronics, 139 111315, 111315. doi: 10.1016/j.bios.2019.111315
2019
Journal Article
Nanoarchitectonics: a new materials horizon for Prussian blue and its analogues
Azhar, Alowasheeir, Li, Yucen, Cai, Zexing, Zakaria, Mohamed Barakat, Masud, Mostafa Kamal, Hossain, Md Shahriar A., Kim, Jeonghun, Zhang, Wei, Na, Jongbeom, Yamauchi, Yusuke and Hu, Ming (2019). Nanoarchitectonics: a new materials horizon for Prussian blue and its analogues. Bulletin of the Chemical Society of Japan, 92 (4), 875-904. doi: 10.1246/bcsj.20180368
2019
Journal Article
Enhanced peroxidase mimetic activity of porous iron oxide nanoflakes
Tanaka, Shunsuke, Masud, Mostafa Kamal, Kaneti, Yusuf Valentino, Shiddiky, Muhammad J. A., Fatehmulla, Amanullah, Aldhafiri, Abdullah M., Farooq, W. Aslam, Bando, Yoshio, Hossain, Md. Shahriar A. and Yamauchi, Yusuke (2019). Enhanced peroxidase mimetic activity of porous iron oxide nanoflakes. ChemNanoMat, 5 (4), 506-513. doi: 10.1002/cnma.201800487
2019
Journal Article
Avoiding pre-isolation step in exosome analysis: direct isolation and sensitive detection of exosomes using gold-loaded nanoporous ferric oxide nanozymes
Boriachek, Kseniia, Masud, Mostafa Kamal, Palma, Carlos, Phan, Hoang-Phuong, Yamauchi, Yusuke, Hossain, Md Shahriar A., Nguyen, Nam-Trung, Salomon, Carlos and Shiddiky, Muhammad J. A. (2019). Avoiding pre-isolation step in exosome analysis: direct isolation and sensitive detection of exosomes using gold-loaded nanoporous ferric oxide nanozymes. Analytical Chemistry, 91 (6), 3827-3834. doi: 10.1021/acs.analchem.8b03619
2019
Journal Article
Transparent crystalline cubic SiC-on-glass electrodes enable simultaneous electrochemistry and optical microscopy
Phan, Hoang-Phuong, Masud, Mostafa Kamal, Vadivelu, Raja Kumar, Dinh, Toan, Nguyen, Tuan-Khoa, Ngo, Kieu, Dao, Dzung Viet, Shiddiky, Muhammad J. A., Hossain, Md Shahriar A., Yamauchi, Yusuke and Nguyen, Nam-Trung (2019). Transparent crystalline cubic SiC-on-glass electrodes enable simultaneous electrochemistry and optical microscopy. Chemical Communications, 55 (55), 7978-7981. doi: 10.1039/c9cc03082d
2019
Journal Article
Nanoarchitecture frameworks for electrochemical miRNA detection
Masud, Mostafa Kamal, Umer, Muhammad, Hossain, Md. Shahriar A., Yamauchi, Yusuke, Nguyen, Nam-Trung and Shiddiky, Muhammad J.A. (2019). Nanoarchitecture frameworks for electrochemical miRNA detection. Trends in Biochemical Sciences, 44 (5), 433-452. doi: 10.1016/j.tibs.2018.11.012
2018
Journal Article
Detection of FGFR2: FAM76A fusion gene in circulating tumor RNA based on catalytic signal amplification of graphene oxide-loaded magnetic nanoparticles
Gorgannezhad, Lena, Umer, Muhammad, Kamal Masud, Mostafa, Yamauchi, Yusuke, A.Hossain, Shahriar, Tanaka, Shunsuke, Salomon, Carlos, Kline, Richard, Nguyen, Nam-Trung and Shiddiky, Muhammad J. A. (2018). Detection of FGFR2: FAM76A fusion gene in circulating tumor RNA based on catalytic signal amplification of graphene oxide-loaded magnetic nanoparticles. Electroanalysis, 30 (10), 2293-2301. doi: 10.1002/elan.201800282
2018
Journal Article
Graphene-oxide-loaded superparamagnetic iron oxide nanoparticles for ultrasensitive electrocatalytic detection of MicroRNA
Islam, Md. Nazmul, Gorgannezhad, Lena, Masud, Mostafa Kamal, Tanaka, Shunsuke, Hossain, Md. Shahriar A., Yamauchi, Yusuke, Nam-Trung Nguyen, and Shiddiky, Muhammad J. A. (2018). Graphene-oxide-loaded superparamagnetic iron oxide nanoparticles for ultrasensitive electrocatalytic detection of MicroRNA. Chemelectrochem, 5 (17), 2488-2495. doi: 10.1002/celc.201800339
2018
Journal Article
Porous nanozymes: the peroxidase-mimetic activity of mesoporous iron oxide for the colorimetric and electrochemical detection of global DNA methylation
Bhattacharjee, Ripon, Tanaka, Shunsuke, Moriam, Sofia, Masud, Mostafa Kamal, Lin, Jianjian, Alshehri, Saad M., Ahamad, Tansir, Salunkhe, Rahul R., Nam-Trung Nguyen,, Yamauchi, Yusuke, Hossain, Md. Shahriar A. and Shiddiky, Muhammad J. A. (2018). Porous nanozymes: the peroxidase-mimetic activity of mesoporous iron oxide for the colorimetric and electrochemical detection of global DNA methylation. Journal of Materials Chemistry B, 6 (29), 4783-4791. doi: 10.1039/c8tb01132j
2018
Journal Article
Gold-loaded nanoporous ferric oxide nanocubes for electrocatalytic detection of microRNA at attomolar level
Islam, Md. Nazmul, Masud, Mostafa Kamal, Nam-Trung Nguyen,, Gopalan, Vinod, Alamri, Hatem R., Alothman, Zeid A., Al Hossain, Md. Shahriar, Yamauchi, Yusuke, Lam, Alfred K. and Shiddiky, Muhammad J. A. (2018). Gold-loaded nanoporous ferric oxide nanocubes for electrocatalytic detection of microRNA at attomolar level. Biosensors and Bioelectronics, 101, 275-281. doi: 10.1016/j.bios.2017.09.027
2017
Journal Article
A PCR-free electrochemical method for messenger RNA detection in cancer tissue samples
Islam, Md. Nazmul, Gopalan, Vinod, Hague, Md. Hakimul, Masud, Mostafa Kamal, Al Hossain, Shahriar, Yamauchi, Yusuke, Nam-Trung Nguyen,, Lam, Alfred King-Yin and Shiddiky, Muhammad J. A. (2017). A PCR-free electrochemical method for messenger RNA detection in cancer tissue samples. Biosensors and Bioelectronics, 98, 227-233. doi: 10.1016/j.bios.2017.06.051
2017
Journal Article
Correction: Gold-loaded nanoporous iron oxide nanocubes: a novel dispersible capture agent for tumor-associated autoantibody analysis in serum (vol 9, pg 8805, 2017)
Yadav, Sharda, Masud, Mostafa Kamal, Islam, Md. Nazmul, Gopalan, Vinod, Lam, Alfred King-yin, Tanaka, Shunsuke, Nam-Trung Nguyen, Al Hossain, Md. Shahriar, Li, Cuiling, Yamauchi, Yusuke and Shiddiky, Muhammad J. A. (2017). Correction: Gold-loaded nanoporous iron oxide nanocubes: a novel dispersible capture agent for tumor-associated autoantibody analysis in serum (vol 9, pg 8805, 2017). Nanoscale, 9 (36), 13829-13829. doi: 10.1039/c7nr90194a
2017
Journal Article
Electrochemical biosensing strategies for DNA methylation analysis
Hossain, Tanvir, Mahmudunnabi, Golam, Masud, Mostafa Kamal, Islam, Md. Nazmul, Ooi, Lezanne, Konstantinov, Konstantin, Al Hossain, Md Shahriar, Martinac, Boris, Alici, Gursel, Nguyen, Nam-Trung and Shiddiky, Muhammad J. A. (2017). Electrochemical biosensing strategies for DNA methylation analysis. Biosensors and Bioelectronics, 94, 63-73. doi: 10.1016/j.bios.2017.02.026
2017
Journal Article
Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA
Masud, Mostafa Kamal, Islam, Md. Nazmul, Haque, Md. Hakimul, Tanaka, Shunsuke, Gopalan, Vinod, Alici, Gursel, Nguyen, Nam-Trung, Lam, Alfred K., Hossain, Md. Shahriar A., Yamauchi, Yusuke and Shiddiky, Muhammad J. A. (2017). Gold-loaded nanoporous superparamagnetic nanocubes for catalytic signal amplification in detecting miRNA. Chemical Communications, 53 (58), 8231-8234. doi: 10.1039/c7cc04789d
2017
Journal Article
Quantification of gene-specific DNA methylation in oesophageal cancer via electrochemistry
Haque, Md. Hakimul, Gopalan, Vinod, Islam, Md. Nazmul, Masud, Mostafa Kamal, Bhattacharjee, Ripon, Al Hossain, Md. Shahriar, Nguyen, Nam-Trung, Lam, Alfred K. and Shiddiky, Muhammad J. A. (2017). Quantification of gene-specific DNA methylation in oesophageal cancer via electrochemistry. Analytica Chimica Acta, 976, 84-93. doi: 10.1016/j.aca.2017.04.034
2017
Journal Article
Gold-loaded nanoporous iron oxide nanocubes: a novel dispersible capture agent for tumor-associated autoantibody analysis in serum
Yadav, Sharda, Masud, Mostafa Kamal, Islam, Md. Nazmul, Gopalan, Vinod, Lam, Alfred King-yin, Tanaka, Shunsuke, Nguyen, Nam-Trung, Al Hossain, Md. Shahriar, Li, Cuiling, Yamauchi, Md. Yusuke and Shiddiky, Muhammad J. A. (2017). Gold-loaded nanoporous iron oxide nanocubes: a novel dispersible capture agent for tumor-associated autoantibody analysis in serum. Nanoscale, 9 (25), 8805-8814. doi: 10.1039/c7nr03006a
2017
Journal Article
RNA biomarkers: diagnostic and prognostic potentials and recent developments of electrochemical biosensors
Islam, Md Nazmul, Masud, Mostafa Kamal, Haque, Md Hakimul, Al Hossain, Md Shahriar, Yamauchi, Yusuke, Nam-Trung Nguyen, and Shiddiky, Muhammad J. A. (2017). RNA biomarkers: diagnostic and prognostic potentials and recent developments of electrochemical biosensors. Small Methods, 1 (7) 1700131, 1700131. doi: 10.1002/smtd.201700131
2016
Journal Article
Synthesis, characterization and catalytic activities of palladium(II) nitroaryl complexes
Huq, Mohammad Maududul, Robiur Rahman, Md., Naher, Masnun, Khan, Mohammad Mizanur Rahman, Masud, Mostafa Kamal, Hossain, Golam Mohammad Golzar, Zhu, Nianyong, Lo, Yih Hsing, Younus, Muhammad and Wong, Wai-Yeung (2016). Synthesis, characterization and catalytic activities of palladium(II) nitroaryl complexes. Journal of Inorganic and Organometallic Polymers and Materials, 26 (6), 1243-1252. doi: 10.1007/s10904-016-0434-3
Supervision
Availability
- Dr Mostafa Kamal Masud is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Nanodiagnostics for early detection and monitoring of ovarian cancer
Principal Advisor
Other advisors: Professor Yusuke Yamauchi, Associate Professor MD Shahriar Hossain
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Doctor Philosophy
Nanoarchitecture-integrated Iron Oxide-based Platform for Biosensing Applications
Associate Advisor
Other advisors: Professor Carlos Salomon Gallo, Associate Professor MD Shahriar Hossain, Dr Valentino Kaneti, Professor Yusuke Yamauchi
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Doctor Philosophy
Nanoarchitectured Multifunctional Porous Superparamagnetic Nanoparticles
Associate Advisor
Other advisors: Professor Carlos Salomon Gallo, Associate Professor MD Shahriar Hossain, Dr Valentino Kaneti, Professor Yusuke Yamauchi
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Doctor Philosophy
Nanoarchitectured Multifunctional Porous Superparamagnetic Nanoparticles
Associate Advisor
Other advisors: Professor Carlos Salomon Gallo, Associate Professor MD Shahriar Hossain, Dr Valentino Kaneti, Professor Yusuke Yamauchi
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Doctor Philosophy
Magneto Plasmonic Mesoporous nanostructures for the profiling of clinically relevant biomarkers
Associate Advisor
Other advisors: Professor Yusuke Yamauchi, Dr Valentino Kaneti, Associate Professor MD Shahriar Hossain
Completed supervision
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2024
Doctor Philosophy
Nanoarchitectured Mesoporous Gold-Alloy for microRNA Sensing
Associate Advisor
Other advisors: Professor Carlos Salomon Gallo, Professor Yusuke Yamauchi, Dr Valentino Kaneti, Associate Professor MD Shahriar Hossain
Media
Enquiries
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