Overview
Availability
- Professor Barbara Leggett is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Medicine Surgery, The University of Queensland
- Doctoral Diploma of Medicine, The University of Queensland
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
- Royal College of Physicians, Royal College of Physicians
Works
Search Professor Barbara Leggett’s works on UQ eSpace
2024
Journal Article
Alcohol does not impact chronic hepatitis C treatment outcomes but increases risk for progressive liver disease: Findings from a prospective multicentre Australian study (OPERA-C)
Clark, Paul J, Valery, Patricia C, Strasser, Simone I, Weltman, Martin, Thompson, Alex, Levy, Miriam T, Leggett, Barbara, Zekry, Amany, Rong, Julian, Sinclair, Marie, George, Jacob, Sievert, William, MacQuillan, Gerry, Tse, Edmund, Nicoll, Amanda, Wade, Amanda, Cheng, Wendy and Roberts, Stuart K (2024). Alcohol does not impact chronic hepatitis C treatment outcomes but increases risk for progressive liver disease: Findings from a prospective multicentre Australian study (OPERA-C). Drug and Alcohol Review, 43 (6), 1559-1572. doi: 10.1111/dar.13914
2024
Journal Article
Rising hospital admissions for alcohol-related cirrhosis and the impact of sex and comorbidity – a data linkage study
Sarraf, B., Skoien, R., Hartel, G., O'Beirne, J., Clark, P. J., Collins, L., Leggett, B., Powell, E. E. and Valery, P. C. (2024). Rising hospital admissions for alcohol-related cirrhosis and the impact of sex and comorbidity – a data linkage study. Public Health, 232, 178-187. doi: 10.1016/j.puhe.2024.04.030
2024
Journal Article
Spontaneous remission of Cronkhite-Canada syndrome without immunosuppressive medication in the context of decompensated cirrhosis: A case report
Deacon, Anthony J., Hoey, Paris, Grimpen, Florian, Francis, Leo, Brown, Ian and Leggett, Barbara (2024). Spontaneous remission of Cronkhite-Canada syndrome without immunosuppressive medication in the context of decompensated cirrhosis: A case report. Clinical Case Reports, 12 (6) e8985, e8985. doi: 10.1002/ccr3.8985
2024
Journal Article
High prevalence of diabetes among young First Nations Peoples with metabolic dysfunction-associated steatotic liver disease: a population-based study in Australia
Valery, Patricia C., Roche, Shruti, Brown, Catherine, O’Beirne, James, Hartel, Gunter, Leggett, Barbara, Skoien, Richard and Powell, Elizabeth E. (2024). High prevalence of diabetes among young First Nations Peoples with metabolic dysfunction-associated steatotic liver disease: a population-based study in Australia. International Journal for Equity in Health, 23 (1) 84, 1-11. doi: 10.1186/s12939-024-02153-z
2024
Journal Article
Efficacy, safety, and pharmacokinetics of capsid assembly modulator linvencorvir plus standard of care in chronic hepatitis B patients
Hou, Jinlin, Gane, Edward, Balabanska, Rozalina, Zhang, Wenhong, Zhang, Jiming, Lim, Tien Huey, Xie, Qing, Yeh, Chau-Ting, Yang, Sheng-Shun, Liang, Xieer, Komolmit, Piyawat, Leerapun, Apinya, Xue, Zenghui, Chen, Ethan, Zhang, Yuchen, Xie, Qiaoqiao, Chang, Ting-Tsung, Hu, Tsung-Hui, Lim, Seng Gee, Chuang, Wan-Long, Leggett, Barbara, Bo, Qingyan, Zhou, Xue, Triyatni, Miriam, Zhang, Wen and Yuen, Man-Fung (2024). Efficacy, safety, and pharmacokinetics of capsid assembly modulator linvencorvir plus standard of care in chronic hepatitis B patients. Clinical and Molecular Hepatology, 30 (2), 191-205. doi: 10.3350/cmh.2023.0422
2024
Journal Article
Broadening and strengthening the health providers caring for patients with chronic hepatitis C may improve continuity of care
Clark, Paul J., Valery, Patricia C., Strasser, Simone I., Weltman, Martin, Thompson, Alex, Levy, Miriam T., Leggett, Barbara, Zekry, Amany, Rong, Julian, Sinclair, Marie, George, Jacob, Bollipo, Steven, McGarity, Bruce, Sievert, William, MacQuillan, Gerry, Tse, Edmund, Nicoll, Amanda, Wade, Amanda, Cheng, Wendy and Roberts, Stuart K. (2024). Broadening and strengthening the health providers caring for patients with chronic hepatitis C may improve continuity of care. Journal of Gastroenterology and Hepatology, 39 (3), 568-575. doi: 10.1111/jgh.16440
2024
Journal Article
Lack of complete biochemical response in autoimmune hepatitis leads to adverse outcome: First report of the IAIHG retrospective registry
Slooter, Charlotte D., Van Den Brand, Floris F., Lleo, Ana, Colapietro, Francesca, Lenzi, Marco, Muratori, Paolo, Kerkar, Nanda, Dalekos, George N., Zachou, Kalliopi, Lucena, M. Isabel, Robles-Díaz, Mercedes, Di Zeo-Sánchez, Daniel E., Andrade, Raúl J., Montano-Loza, Aldo J., Lytvyak, Ellina, Lissenberg-Witte, Birgit I., Maisonneuve, Patrick, Bouma, Gerd, MacEdo, Guilherme, Liberal, Rodrigo, De Boer, Ynto S., Almasio, P., Alvarez, F., Andrade, R., Arikan, C., Assis, D., Bardou-Jacquet, E., Biewenga, M., Van Hoek, B. ... Kuijvenhoven, J. (2024). Lack of complete biochemical response in autoimmune hepatitis leads to adverse outcome: First report of the IAIHG retrospective registry. Hepatology, 79 (3), 538-550. doi: 10.1097/HEP.0000000000000589
2023
Journal Article
Improving palliative and supportive care in advanced cirrhosis: the HepatoCare model of integrated collaborative care
Kearney, Alison, Tiwari, Neha, Cullen, Olivia, Legg, Amy, Arbi, Ismail, Douglas, Carol, Leggett, Barbara, Fenech, Mary, Mina, Joanne, Hoey, Paris and Skoien, Richard (2023). Improving palliative and supportive care in advanced cirrhosis: the HepatoCare model of integrated collaborative care. Internal Medicine Journal, 53 (11), 1963-1971. doi: 10.1111/imj.16248
2023
Journal Article
Diabetes mellitus and the progression of non‐alcoholic fatty liver disease to decompensated cirrhosis: a retrospective cohort study
O'Beirne, James, Skoien, Richard, Leggett, Barbara A., Hartel, Gunter F., Gordon, Louisa G., Powell, Elizabeth E. and Valery, Patricia C. (2023). Diabetes mellitus and the progression of non‐alcoholic fatty liver disease to decompensated cirrhosis: a retrospective cohort study. Medical Journal of Australia, 219 (8), 358-365. doi: 10.5694/mja2.52104
2023
Journal Article
Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study
Hirschfield, Gideon M., Shiffman, Mitchell L., Gulamhusein, Aliya, Kowdley, Kris V., Vierling, John M., Levy, Cynthia, Kremer, Andreas E., Zigmond, Ehud, Andreone, Pietro, Gordon, Stuart C., Bowlus, Christopher L., Lawitz, Eric J., Aspinall, Richard J., Pratt, Daniel S., Raikhelson, Karina, Gonzalez-Huezo, Maria S., Heneghan, Michael A., Jeong, Sook-Hyang, Ladrón de Guevara, Alma L., Mayo, Marlyn J., Dalekos, George N., Drenth, Joost P H, Janczewska, Ewa, Leggett, Barbara A., Nevens, Frederik, Vargas, Victor, Zuckerman, Eli, Corpechot, Christophe, Fassio, Eduardo ... McWherter, Charles A. (2023). Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study. Hepatology, 78 (2), 397-415. doi: 10.1097/HEP.0000000000000395
2023
Journal Article
Post-colonoscopy cancer rate at a tertiary referral hospital in Australia: a data linkage analysis
Lamba, Mehul, Khaing, Myat Myat, Ma, Xiaomin, Ryan, Kimberley, Appleyard, Mark, Leggett, Barbara and Grimpen, Florian (2023). Post-colonoscopy cancer rate at a tertiary referral hospital in Australia: a data linkage analysis. Journal of Gastroenterology and Hepatology, 38 (5), 740-746. doi: 10.1111/jgh.16077
2022
Journal Article
Comparative analysis of Illumina Mouse Methylation BeadChip and reduced-representation bisulfite sequencing for routine DNA methylation analysis
Fennell, Lochlan J., Hartel, Gunter, McKeone, Diane M., Bond, Catherine E., Kane, Alexandra, Leggett, Barbara A., Patch, Ann-Marie and Whitehall, Vicki L.J. (2022). Comparative analysis of Illumina Mouse Methylation BeadChip and reduced-representation bisulfite sequencing for routine DNA methylation analysis. Cell Reports Methods, 2 (11) 100323, 1-14. doi: 10.1016/j.crmeth.2022.100323
2022
Journal Article
Clinicopathological correlates of dysplastic sessile serrated lesion: a prospective cohort study with a high detection rate
Lamba, Mehul, Brown, Ian, Bettington, Mark, Ryan, Kimberley, Hanigan, Katherine, Lasenby, Kay, Dixon, Alicia, Grimpen, Florian, Gan, Chun, Tutticci, Nicholas, Appleyard, Mark and Leggett, Barbara (2022). Clinicopathological correlates of dysplastic sessile serrated lesion: a prospective cohort study with a high detection rate. Gastro Hep Advances, 1 (3), 313-320. doi: 10.1016/j.gastha.2021.12.010
2021
Journal Article
Braf mutation induces rapid neoplastic transformation in the aged and aberrantly methylated intestinal epithelium
Fennell, Lochlan, Kane, Alexandra, Liu, Cheng, McKeone, Diane, Hartel, Gunter, Su, Chang, Bond, Catherine, Bettington, Mark, Leggett, Barbara and Whitehall, Vicki (2021). Braf mutation induces rapid neoplastic transformation in the aged and aberrantly methylated intestinal epithelium. Gut, 71 (6) 322166, 1127-1140. doi: 10.1136/gutjnl-2020-322166
2021
Journal Article
Association of Fusobacterium nucleatum with specific T-cell subsets in the colorectal carcinoma microenvironment
Borowsky, Jennifer, Haruki, Koichiro, Lau, Mai Chan, Costa, Andressa Dias, Vayrynen, Juha P., Ugai, Tomotaka, Arima, Kota, Da Silva, Annacarolina, Felt, Kristen D., Zhao, Melissa, Gurjao, Carino, Twombly, Tyler S., Fujiyoshi, Kenji, Vayrynen, Sara A., Hamada, Tsuyoshi, Mima, Kosuke, Bullman, Susan, Harrison, Tabitha A., Phipps, Amanda I., Peters, Ulrike, Ng, Kimmie, Meyerhardt, Jeffrey A., Song, Mingyang, Giovannucci, Edward L., Wu, Kana, Zhang, Xuehong, Freeman, Gordon J., Huttenhower, Curtis, Garrett, Wendy S. ... Ogino, Shuji (2021). Association of Fusobacterium nucleatum with specific T-cell subsets in the colorectal carcinoma microenvironment. Clinical Cancer Research, 27 (10), 2816-2826. doi: 10.1158/1078-0432.CCR-20-4009
2021
Conference Publication
Clinicopathological Correlates Of Dysplastic Change In Sessile Serrated Lesions
Lamba, Mehul, Ryan, Kimberley, Brown, Ian, Bettington, Mark, Hanigan, Katherine, Gan, Chun H., Grimpen, Florian, Appleyard, Mark and Leggett, Barbara (2021). Clinicopathological Correlates Of Dysplastic Change In Sessile Serrated Lesions. Digestive Disease Week (DDW) 2021, Online, 21-23 May 2021. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(21)02134-x
2021
Journal Article
Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia
Kane, Alexandra M., Liu, Cheng, Fennell, Lochlan J., McKeone, Diane M., Bond, Catherine E., Pollock, Pamela M., Young, Graeme, Leggett, Barbara A. and Whitehall, Vicki L. J. (2021). Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia. British Journal of Cancer, 124 (11), 1820-1827. doi: 10.1038/s41416-021-01339-4
2021
Journal Article
Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study
Kane, Alexandra M., Liu, Cheng, Akhter, Dewan T., McKeone, Diane M., Bell, Craig A., Thurecht, Kristofer J., Leggett, Barbara A. and Whitehall, Vicki L. J. (2021). Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study. Digestive Diseases and Sciences, 66 (12), 4326-4332. doi: 10.1007/s10620-020-06752-y
2020
Journal Article
Pathways to a cancer-free future: a protocol for modelled evaluations to minimise the future burden of colorectal cancer in Australia
Feletto, Eleonora, Lew, Jie-Bin, Worthington, Joachim, He, Emily, Caruana, Michael, Butler, Katherine, Hui, Harriet, Taylor, Natalie, Banks, Emily, Barclay, Karen, Broun, Kate, Butt, Alison, Carter, Rob, Cuff, Jeff, Dessaix, Anita, Ee, Hooi, Emery, Jon, Frayling, Ian M., Grogan, Paul, Holden, Carol, Horn, Christopher, Jenkins, Mark A., Kench, James G., Laaksonen, Maarit A., Leggett, Barbara, Mitchell, Gillian, Morris, Susan, Parkinson, Bonny, St John, D James ... Canfell, Karen (2020). Pathways to a cancer-free future: a protocol for modelled evaluations to minimise the future burden of colorectal cancer in Australia. BMJ Open, 10 (6) e036475, e036475. doi: 10.1136/bmjopen-2019-036475
2020
Journal Article
APC mutation marks an aggressive subtype of BRAF mutant colorectal cancers
Fennell, Lochlan J., Kane, Alexandra, Liu, Cheng, McKeone, Diane, Fernando, Winnie, Su, Chang, Bond, Catherine, Jamieson, Saara, Dumenil, Troy, Patch, Ann-Marie, Kazakoff, Stephen H., Pearson, John V., Waddell, Nicola, Leggett, Barbara and Whitehall, Vicki L. J (2020). APC mutation marks an aggressive subtype of BRAF mutant colorectal cancers. Cancers, 12 (5) 1171, 1-26. doi: 10.3390/cancers12051171
Funding
Past funding
Supervision
Availability
- Professor Barbara Leggett is:
- Available for supervision
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Supervision history
Current supervision
-
Master Philosophy
Yield of neoplastic lesions in a prospective Australian cohort undergoing colonoscopic surveillance in the context of high-quality colonoscopy
Principal Advisor
-
Master Philosophy
Yield of neoplastic lesions in a prospective Australian cohort undergoing colonoscopic surveillance in the context of high-quality colonoscopy
Principal Advisor
-
Master Philosophy
Yield of neoplastic lesions in a prospective Australian cohort undergoing colonoscopic surveillance in the context of high-quality colonoscopy
Principal Advisor
Completed supervision
-
2015
Doctor Philosophy
A clinicopathological and molecular categorisation of serrated colorectal polyps
Principal Advisor
Other advisors: Honorary Professor Vicki Whitehall
-
2010
Doctor Philosophy
DNA methylation throughout the human colorectum: Person, place and pathology
Principal Advisor
Other advisors: Honorary Professor Vicki Whitehall
-
2010
Doctor Philosophy
Communication Between Doctors and the Quality of Patient Care: An Intergroup Perspective
Principal Advisor
Other advisors: Honorary Professor Bernadette Watson
-
2008
Doctor Philosophy
Role of Bone Morphogenetic Protein 3 (BMP3) in Colorectal Carcinogenesis
Principal Advisor
Other advisors: Honorary Professor Vicki Whitehall
-
2006
Master Philosophy
COMPARISON OF ENDOSCOPIC ULTRASOUND AND COMPUTED TOMOGRAPHY FOR THE STAGING AND DETERMINATION OF RESECTABILITY OF PANCREATIC CANCER
Principal Advisor
-
2003
Doctor Philosophy
MOLECULAR GENETICS OF HEPATOCELLULAR CARCINOMA IN HEMOCHROMATOSIS
Principal Advisor
-
2003
Doctor Philosophy
MOLECULAR GENETICS OF HEPATOCELLULAR CARCINOMA
Principal Advisor
Other advisors: Associate Professor Graeme Macdonald
-
2003
Doctor Philosophy
ISOLATION AND CHARACTERISATION OF NOVEL GENES INVOLVED IN COLORECTAL CARCINOGENESIS
Principal Advisor
-
2023
Doctor Philosophy
Morphological and Molecular Characterisation of Colorectal Adenomas and Carcinomas
Associate Advisor
Other advisors: Honorary Professor Vicki Whitehall
-
2021
Doctor Philosophy
Age, DNA Methylation and the Malignant Potential of the Serrated Neoplasia Pathway
Associate Advisor
Other advisors: Honorary Professor Vicki Whitehall
-
2020
Doctor Philosophy
Molecular characterisation of serrated precursors in colorectal carcinoma
Associate Advisor
Other advisors: Honorary Professor Vicki Whitehall
-
2015
Doctor Philosophy
Characterization of BRAF Mutant, Microsatellite Stable Colorectal Cancers
Associate Advisor
Other advisors: Honorary Professor Vicki Whitehall
Media
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