Professor

Barbara Leggett

Email: 
Phone: 
+61 7 3362 0170

Availability

Professor Barbara Leggett is:
Available for supervision

Fields of research

Biological Sciences Psychology Sports science and exercise

Qualifications

  • Bachelor (Honours) of Medicine Surgery, The University of Queensland
  • Doctoral Diploma of Medicine, The University of Queensland
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • Royal College of Physicians, Royal College of Physicians

Search Professor Barbara Leggett’s works on UQ eSpace

170 works between 1990 and 2024
All (170) Journal Article (124) Book Chapter (1) Conference Publication (45)

41 - 60 of 170 works

2016

Journal Article

Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma

Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, McKeone, Diane, Pearson, Sally-Ann, Leggett, Barbara and Whitehall, Vicki (2016). Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma. Gut, 66 (1), 97-106. doi: 10.1136/gutjnl-2015-310456

Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma

2016

Journal Article

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis

Bond, Catherine E., McKeone, Diane M., Kalimutho, Murugan, Bettington, Mark L., Pearson, Sally-Ann, Dumenil, Troy D., Wockner, Leesa F., Burge, Matthew, Leggett, Barbara A. and Whitehall, Vicki L. J. (2016). RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis. Oncotarget, 7 (43), 70589-70600. doi: 10.18632/oncotarget.12130

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis

2016

Journal Article

Serrated tubulovillous adenoma of the large intestine

Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, Mckeone, Diane, Pearson, Sally-Ann, Klein, Kerenaftali, Leggett, Barbara and Whitehall, Vicki (2016). Serrated tubulovillous adenoma of the large intestine. Histopathology, 68 (4), 578-587. doi: 10.1111/his.12788

Serrated tubulovillous adenoma of the large intestine

2015

Journal Article

Aspirin, Ibuprofen, and the Risk for Colorectal Cancer in Lynch Syndrome

Ouakrim, Driss Ait, Dashti, Seyedeh Ghazaleh, Chau, Rowena, Buchanan, Daniel D., Clendenning, Mark, Rosty, Christophe, Winship, Ingrid M., Young, Joanne P., Giles, Graham G., Leggett, Barbara, Macrae, Finlay A., Ahnen, Dennis J., Casey, Graham, Gallinger, Steven, Haile, Robert W., Le Marchand, Loic, Thibodeau, Stephen N., Lindor, Noralane M., Newcomb, Polly A., Potter, John D., Baron, John A., Hopper, John L., Jenkins, Mark A. and Win, Aung Ko (2015). Aspirin, Ibuprofen, and the Risk for Colorectal Cancer in Lynch Syndrome. Journal of the National Cancer Institute, 107 (9) djv170. doi: 10.1093/jnci/djv170

Aspirin, Ibuprofen, and the Risk for Colorectal Cancer in Lynch Syndrome

2015

Journal Article

A clinicopathological and molecular analysis of 200 traditional serrated adenomas

Bettington, Mark L., Walker, Neal I., Rosty, Christophe, Brown, Ian S., Clouston, Andrew D., McKeone, Diane M., Pearson, Sally Ann, Klein, Kerenaftali, Leggett, Barbara A. and Whitehall, Vicki L. (2015). A clinicopathological and molecular analysis of 200 traditional serrated adenomas. Modern Pathology, 28 (3), 414-427. doi: 10.1038/modpathol.2014.122

A clinicopathological and molecular analysis of 200 traditional serrated adenomas

2015

Journal Article

Methylation and expression of the tumour suppressor, PRDM5, in colorectal cancer and polyp subgroups

Bond, Catherine E., Bettington, Mark L., Pearson, Sally-Ann, McKeone, Diane M., Leggett, Barbara A. and Whitehall, Vicki (2015). Methylation and expression of the tumour suppressor, PRDM5, in colorectal cancer and polyp subgroups. BMC Cancer, 15 (1) 20, 20. doi: 10.1186/s12885-015-1011-9

Methylation and expression of the tumour suppressor, PRDM5, in colorectal cancer and polyp subgroups

2015

Journal Article

Colorectal cancer screening

Leggett, B.A. and Hewett, D.G. (2015). Colorectal cancer screening. Internal Medicine Journal, 45 (1), 6-15. doi: 10.1111/imj.12636

Colorectal cancer screening

2015

Conference Publication

Wnt and MAPK signalling in colorectal cancer morphology

Fernando, W., Mckeone, D., Bettington, M., Pearson, S., Leggett, B. and Whitehall, V. (2015). Wnt and MAPK signalling in colorectal cancer morphology. Gastro 2015 GESA‐AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, QLD Australia, 28-September-1 October 2015. HOBOKEN: WILEY-BLACKWELL.

Wnt and MAPK signalling in colorectal cancer morphology

2015

Conference Publication

A clinicopathological and molecular analysis of 107 sessile serrated adenomas with dysplasia

Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, Pearson, Sally-Ann, McKeone, Diane, Leggett, Barbara and Whitehall, Vicki (2015). A clinicopathological and molecular analysis of 107 sessile serrated adenomas with dysplasia. 104th Annual Meeting of the United States and Canadian Academy of Pathology, Boston, United States, 21-27 March, 2015. London, United Kingdom: Nature Publishing Group. doi: 10.1038/labinvest.2015.11

A clinicopathological and molecular analysis of 107 sessile serrated adenomas with dysplasia

2015

Conference Publication

Effects of the porcupine inhibitor, LGK974, on RNF43 mutant and wild type colorectal cancer cell lines

Bond, C., Kalimutho, M., Bettington, M., Pearson, S., Leggett, B. and Whitehall, V. (2015). Effects of the porcupine inhibitor, LGK974, on RNF43 mutant and wild type colorectal cancer cell lines. Abstracts of Gastro 2015 GESA‐AGW and WGO International Congress, Gastroenterological Society of Australia Australian Gastroenterology Week 2015 | World Congress of Gastroenterology, Brisbane, QLD, Australia, 28 September‐2 October 2015. Richmond, VIC, Australia: John Wiley & Sons.

Effects of the porcupine inhibitor, LGK974, on RNF43 mutant and wild type colorectal cancer cell lines

2015

Journal Article

Remoteness, race and social disadvantage: Disparities in hepatocellular carcinoma incidence and survival in Queensland, Australia

Clark, Paul J., Stuart, Katherine A., Leggett, Barbara A., Crawford, Darrell H., Boyd, Peter, Fawcett, Jonathan, Whiteman, David C. and Baade, Peter D. (2015). Remoteness, race and social disadvantage: Disparities in hepatocellular carcinoma incidence and survival in Queensland, Australia. Liver International, 35 (12), 2584-2594. doi: 10.1111/liv.12853

Remoteness, race and social disadvantage: Disparities in hepatocellular carcinoma incidence and survival in Queensland, Australia

2014

Journal Article

Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype

Whitehall, V. L. J., Dumenil, T. D., McKeone, D. M., Bond, C. E., Bettington, M. L., Buttenshaw, R. L., Bowdler, L., Montgomery, G. W., Wockner, L. F. and Leggett, B. A. (2014). Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype. Epigenetics, 9 (11), 1454-1460. doi: 10.4161/15592294.2014.971624

Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype

2014

Journal Article

Genome-wide DNA methylation analysis of formalin-fixed paraffin embedded colorectal cancer tissue

Dumenil, Troy D., Wockner, Leesa F., Bettington, Mark, Mckeone, Diane M., Klein, Kerenaftali, Bowdler, Lisa M., Montgomery, Grant W., Leggett, Barbara A. and Whitehall, Vicki L. J. (2014). Genome-wide DNA methylation analysis of formalin-fixed paraffin embedded colorectal cancer tissue. Genes Chromosomes and Cancer, 53 (7), 537-548. doi: 10.1002/gcc.22164

Genome-wide DNA methylation analysis of formalin-fixed paraffin embedded colorectal cancer tissue

2014

Journal Article

The CIMP phenotype in BRAF mutant serrated polyps from a prospective colonoscopy patient cohort

Fernando, Winnie C., Miranda, Mariska S., Worthley, Daniel L., Togashi, Kazutomo, Watters, Dianne J., Leggett, Barbara A. and Spring, Kevin J. (2014). The CIMP phenotype in BRAF mutant serrated polyps from a prospective colonoscopy patient cohort. Gastroenterology Research and Practice, 2014 (8) 374926, 1084-1091. doi: 10.1155/2014/374926

The CIMP phenotype in BRAF mutant serrated polyps from a prospective colonoscopy patient cohort

2014

Journal Article

Microsatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability

Bond, Catherine E., Nancarrow, Derek J., Wockner, Leesa F., Wallace, Leanne, Montgomery, Grant W., Leggett, Barbara A. and Whitehall, Vicki L. J. (2014). Microsatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability. Plos One, 9 (3) e91739, e91739. doi: 10.1371/journal.pone.0091739

Microsatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability

2014

Journal Article

Copper removal strategies for Wilson's disease crisis in the ICU

Reynolds, H. V., Talekar, C. R., Bellapart, J., Leggett, B. A. and Boots, R. J. (2014). Copper removal strategies for Wilson's disease crisis in the ICU. Anaesthesia and Intensive Care, 42 (2), 253-257.

Copper removal strategies for Wilson's disease crisis in the ICU

2014

Conference Publication

Tubulovillous adenoma with prominent architectural serration - a clinicopathological and molecular appraisal of a new subtype of colorectal polyp

Bettington, M., Walker, N., Brown, I., Rosty, C., Clouston, A., Pearson, S-A, Mckeone, D., Leggett, B. and Whitehall, V. (2014). Tubulovillous adenoma with prominent architectural serration - a clinicopathological and molecular appraisal of a new subtype of colorectal polyp. Australian Gastroenterology Week 2014, Broadbeach, Australia, 22-24 October 2014. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12736_2

Tubulovillous adenoma with prominent architectural serration - a clinicopathological and molecular appraisal of a new subtype of colorectal polyp

2014

Conference Publication

Methylation and expression of the tumor suppressor, PRDM5, in colorectal cancer subgroups

Bond, C., Bettington, M., Pearson, S., Mckeone, D., Wockner, L., Leggett, B. and Whitehall, V. (2014). Methylation and expression of the tumor suppressor, PRDM5, in colorectal cancer subgroups. Australian Gastroenterology Week 2014, Broadbeach, QLD Australia, 22‐24 October 2014. HOBOKEN: WILEY-BLACKWELL.

Methylation and expression of the tumor suppressor, PRDM5, in colorectal cancer subgroups

2014

Conference Publication

Wnt signaling in an unselected series of colorectal carcinomas

Bettington, M., Bond, C., Brown, I., Walker, N., Rosty, C., Clouston, A., Pearson, S-A, Mckeone, D., Leggett, B. and Whitehall, V. (2014). Wnt signaling in an unselected series of colorectal carcinomas. Australian Gastroenterology Week 2014, Broadbeach, Australia, 22-24 October 2014. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.12736_2

Wnt signaling in an unselected series of colorectal carcinomas

2014

Conference Publication

Integrated genome wide DNA methylation and gene expression analysis identifies subgroups of colorectal cancer with distinct molecular and clinical features

Dumenil, T. D., Klein, K., Wockner, L. F., Mckeone, D. M., Bowdler, L. M., Montgomery, G. W., Leggett, B. A. and Whitehall, V. L. J. (2014). Integrated genome wide DNA methylation and gene expression analysis identifies subgroups of colorectal cancer with distinct molecular and clinical features. Australian Gastroenterology Week 2014, Broadbeach, QLD Australia, 22‐24 October 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.

Integrated genome wide DNA methylation and gene expression analysis identifies subgroups of colorectal cancer with distinct molecular and clinical features

Past funding

  • 2006 - 2007
    A Double-blind, randomized, placebo-controlled multi-center, Phase II parallel dose-ranging study to assess the antifibrotic activity of G1262570 in chronic hepatitis C subjects with hepatic fibrosis
    Glaxo Smith Kline Aust. Pty Ltd
    Open grant

Availability

Professor Barbara Leggett is:
Available for supervision

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Supervision history

Current supervision

  • Master Philosophy

    Yield of neoplastic lesions in a prospective Australian cohort undergoing colonoscopic surveillance in the context of high-quality colonoscopy

    Principal Advisor

  • Master Philosophy

    Yield of neoplastic lesions in a prospective Australian cohort undergoing colonoscopic surveillance in the context of high-quality colonoscopy

    Principal Advisor

  • Master Philosophy

    Yield of neoplastic lesions in a prospective Australian cohort undergoing colonoscopic surveillance in the context of high-quality colonoscopy

    Principal Advisor

Completed supervision

Enquiries

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