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Professor Sandro Porceddu
Professor

Sandro Porceddu

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Overview

Background

Profile Summary

Dr Sandro Porceddu is an internationally recognised radiation oncologist and a leading authority in head and neck and skin cancer. With over 20 years experience in medicine his areas of clinical expertise include head and neck cancer, skin cancer, sarcoma and lymphoma. He is currently a senior radiation oncologist and Director of radiation oncology research at the Princess Alexandra Hospital, Brisbane, Professor of Medicine, University of Queensland and Associate Editor for the International Head and Neck journal, Oral Oncology.

Dr Porceddu is a nationally and internationally recognised cancer advocate through his involvement in high-level committees, engagement with key policymakers, community education and media roles.

Career Summary

Professor Porceddu completed his medical degree at Monash University before undertaking his residency at Monash Medical Centre, Melbourne. He commenced his specialist training in radiation oncology at the Peter MacCallum Cancer Centre in 1996 and was made Fellow of the Royal Australian and New Zealand College of Radiologists, Faculty of Radiation Oncology in 2000. After working as a consultant radiation oncologist at PeterMac for several years he moved to the Princess Alexandra Hospital in 2004.

Professional Committees and Organisations

Professor Porceddu has been the President of the Clinical Oncology Society of Australia (COSA), the peak organisation for cancer-related health professionals, and the Trans Tasman Radiation Oncology Group (TROG), one of the largest cancer collaborative trials group in Australia/New Zealand. He has served on numerous national and international professional and academic committees including the board of the Cancer Council of Australia, the National Cancer Expert Reference Group for the Commonwealth and the International Union for the Control of Cancer (UICC) TNM Expert Advisory Panel.

Currently, he is the Chair of the Cancer Council Queensland Co-operative Oncology Group, a committee that provides over $1.2M per annum to support clinical research throughout Queensland and is on the board of the of the Head and Neck Cancer InterGroup (HNCIG), a group of leading world cancer experts dedicated to promoting the global harmonisation of head and neck cancer research and treatment.

Academic Highlights

Professor Porceddu runs an active clinical research program with over 150 peer-review articles, book chapters, published abstracts, invited reviews and commentaries. He has received invitations to speak at major international conferences such as the American Society of Clinical Oncology (ASCO) meeting and publish in prestigious journals such as the Lancet Oncology and Journal of Clinical Oncology.

Awards

Trans Tasman Radiation Oncology Group Outstanding Contribution

American Head and Neck Society Chris O’Brien Travelling Scholar

Pre-eminent status by Queensland Health

Rouse Fellowship, Royal Australian and New Zealand College of Radiologists

Teaching

Dr Porceddu has had a life-long commitment to teaching and is a supervisor and mentor to Doctor of Philosophy and Master of Philosophy candidates, Clinical Research Fellows, MBBS Honours students, resident, registrars and other allied health professionals.

Availability

Professor Sandro Porceddu is:
Available for supervision

Qualifications

  • Bachelor of Science, Monash University
  • Bachelor of Medicine and Surgery and Medical Science, Monash University
  • Doctoral Diploma of Medicine, The University of Queensland

Research impacts

Dr Porceddu’s has been investigating methods to reduce the morbidity of treatment, improve cure rates and quality of life for cancer patients. He runs an active head and neck/skin cancer research program and is the principal investigator of numerous trials including an NHMRC-supported Randomised Phase III trial on head and neck skin cancer (POST TROG 05.01). In line with his research goals he has been examining the integration of radiation therapy and new technologies in the management of head and neck cancer and has received his Doctorate of Medicine (MD) on this topic with UQ. His current research on Positron Emission Tomography in the management of the neck following chemo-radiotherapy has been internationally recognised and incorporated into the USA National Comprehensive Cancer Network (NCCN) guidelines. He has been the recipient of over $3.91M in competitive funding, including one recently closed and two open NHMRC grants.

Works

Search Professor Sandro Porceddu’s works on UQ eSpace

175 works between 1999 and 2025

1 - 20 of 175 works

2025

Journal Article

Predictors of distant metastatic recurrence in head and neck cutaneous squamous cell carcinoma with lymph node metastases treated with curative intent: A multicenter study

Ebrahimi, Ardalan, Gupta, Ruta, Mcdowell, Lachlan, Magarey, Matthew J. R., Smith, Paul N., Schulte, Klaus-Martin, Perriman, Diana M., Veness, Michael, Porceddu, Sandro, Low, Tsu-Hui Hubert, Fowler, Allan and Clark, Jonathan R. (2025). Predictors of distant metastatic recurrence in head and neck cutaneous squamous cell carcinoma with lymph node metastases treated with curative intent: A multicenter study. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck, 47 (1), 254-262. doi: 10.1002/hed.27912

Predictors of distant metastatic recurrence in head and neck cutaneous squamous cell carcinoma with lymph node metastases treated with curative intent: A multicenter study

2024

Journal Article

Geospatial analyses demonstrate variation of cutaneous T-cell lymphomas across Australia, providing insights into possible causes

Campbell, Belinda A., Baade, Peter D., Dasgupta, Paramita, Cameron, Jessica K., Porceddu, Sandro V., Prince, H. Miles and Thursky, Karin (2024). Geospatial analyses demonstrate variation of cutaneous T-cell lymphomas across Australia, providing insights into possible causes. British Journal of Dermatology ljae476. doi: 10.1093/bjd/ljae476

Geospatial analyses demonstrate variation of cutaneous T-cell lymphomas across Australia, providing insights into possible causes

2024

Journal Article

Determinants of Prognosis in Head and Neck Cutaneous Squamous Cell Carcinoma With Nodal Metastases

Ebrahimi, Ardalan, Gupta, Ruta, McDowell, Lachlan, Magarey, Matthew J. R., Smith, Paul N., Schulte, Klaus-Martin, Perriman, Diana M., Veness, Michael, Porceddu, Sandro, Low, Tsu-Hui Hubert, Fowler, Allan and Clark, Jonathan R. (2024). Determinants of Prognosis in Head and Neck Cutaneous Squamous Cell Carcinoma With Nodal Metastases. Jama Otolaryngology-Head & Neck Surgery, 150 (11), e1-e9. doi: 10.1001/jamaoto.2024.3103

Determinants of Prognosis in Head and Neck Cutaneous Squamous Cell Carcinoma With Nodal Metastases

2024

Conference Publication

A phase 1 clinical trial of DB-020 intratympanic injections administered prior to high-dose cisplatin chemotherapy to reduce ototoxicity

Panizza, Benedict J., O'Leary, Stephen John, Hart, Christopher David, Diwakarla, Chandra Sai, Barnett, Catherine, Lapuerta, Pablo, Lee, John, Raines, Shane, Quigley, Tera, Wolff, Heather M., Keilty, John, Ladwa, Rahul, Porceddu, Sandro V., McGrath, Margaret, Seetharamu, Nagashree, Fua, Tsien and Rischin, Danny (2024). A phase 1 clinical trial of DB-020 intratympanic injections administered prior to high-dose cisplatin chemotherapy to reduce ototoxicity. 2024 ASCO Annual Meeting, Chicago, IL United States, 31 May - 4 June 2024. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2024.42.16_suppl.6100

A phase 1 clinical trial of DB-020 intratympanic injections administered prior to high-dose cisplatin chemotherapy to reduce ototoxicity

2024

Journal Article

Human papillomavirus associated oropharyngeal cancer now the most common mucosal head and neck cancer in Queensland

Porceddu, Sandro, Negrello, Theresa, Rawson, Neal, Dunn, Nathan, Batstone, Martin, Collins, Michael, Dowthwaite, Sam, Hughes, Brett G. M., Kenny, Liz, Ladwa, Rahul, Panizza, Ben and Cossio, Danica (2024). Human papillomavirus associated oropharyngeal cancer now the most common mucosal head and neck cancer in Queensland. Journal of Medical Imaging and Radiation Oncology, 68 (4), 472-480. doi: 10.1111/1754-9485.13643

Human papillomavirus associated oropharyngeal cancer now the most common mucosal head and neck cancer in Queensland

2024

Journal Article

Characterising B cell expression and prognostic significance in human papillomavirus positive oropharyngeal cancer

Young, Richard J., Angel, Christopher, Bressel, Mathias, Pizzolla, Angela, Thai, Alesha A., Porceddu, Sandro V., Liu, Howard, Idrizi, Rejhan, Metta, Jana, Lim, Annette M., Solomon, Benjamin J. and Rischin, Danny (2024). Characterising B cell expression and prognostic significance in human papillomavirus positive oropharyngeal cancer. Oral Oncology, 150 106687. doi: 10.1016/j.oraloncology.2024.106687

Characterising B cell expression and prognostic significance in human papillomavirus positive oropharyngeal cancer

2023

Conference Publication

High-plex spatial profiling of cutaneous squamous cell carcinoma to identify biomarkers associated with clinical outcomes: The cMIC study

Ladwa, R., Monkman, J., Sadeghirad, H., Cooper, C., Belz, G., Bowman, J., Schaider, H., Liu, H., Kulasinghe, A. and Porceddu, S. (2023). High-plex spatial profiling of cutaneous squamous cell carcinoma to identify biomarkers associated with clinical outcomes: The cMIC study. ESMO Congress 2023, Madrid, Spain, 20-24 October 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.annonc.2023.09.2278

High-plex spatial profiling of cutaneous squamous cell carcinoma to identify biomarkers associated with clinical outcomes: The cMIC study

2023

Journal Article

Patient-Reported Symptom Severity, Health-Related Quality of Life, and Emotional Distress Trajectories During and After Radiation Therapy for Human Papillomavirus–Associated Oropharyngeal Cancer: A TROG 12.01 Secondary Analysis

McDowell, Lachlan, Bressel, Mathias, King, Madeleine T., Corry, June, Kenny, Lizbeth, Porceddu, Sandro, Wratten, Christopher, Macann, Andrew, Jackson, James E. and Rischin, Danny (2023). Patient-Reported Symptom Severity, Health-Related Quality of Life, and Emotional Distress Trajectories During and After Radiation Therapy for Human Papillomavirus–Associated Oropharyngeal Cancer: A TROG 12.01 Secondary Analysis. International Journal of Radiation Oncology Biology Physics, 116 (5), 1110-1125. doi: 10.1016/j.ijrobp.2023.02.041

Patient-Reported Symptom Severity, Health-Related Quality of Life, and Emotional Distress Trajectories During and After Radiation Therapy for Human Papillomavirus–Associated Oropharyngeal Cancer: A TROG 12.01 Secondary Analysis

2023

Conference Publication

A proteomic signature associated with prognosis in HPV-related locally advanced oropharyngeal squamous cell carcinoma (LA-OPSCC)

Liu, Jia (Jenny), Jackson, Christopher, Anees, Asim, Noor, Zainab, Williams, Steven, Porceddu, Sandro, Liu, Howard, Ladwa, Rahul, Whitfield, Joseph, Reddel, Roger R., Zhong, Qing, Panizza, Benedict J. and Robinson, Phillip J (2023). A proteomic signature associated with prognosis in HPV-related locally advanced oropharyngeal squamous cell carcinoma (LA-OPSCC). 2023 ASCO Annual Meeting, Chicago, IL United States, 2-6 June 2023. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2023.41.16_suppl.6055

A proteomic signature associated with prognosis in HPV-related locally advanced oropharyngeal squamous cell carcinoma (LA-OPSCC)

2023

Journal Article

The Current Treatment Landscape of Cutaneous Squamous Cell Carcinoma

Chong, Chia Yuen, Goh, Michelle S., Porceddu, Sandro V., Rischin, Danny and Lim, Annette M. (2023). The Current Treatment Landscape of Cutaneous Squamous Cell Carcinoma. American Journal of Clinical Dermatology, 24 (1), 25-40. doi: 10.1007/s40257-022-00742-8

The Current Treatment Landscape of Cutaneous Squamous Cell Carcinoma

2023

Book Chapter

Regional radiotherapy in head and neck non-melanoma skin cancer 

Smith, Justin and Porceddu, Sandro V. (2023). Regional radiotherapy in head and neck non-melanoma skin cancer . Radiotherapy in skin cancer: a practical guide on indications and techniques. (pp. 145-152) edited by Kurian Jones Joseph, Michael J. Veness, Elizabeth Barnes and Agata Rembielak. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-44316-9_14

Regional radiotherapy in head and neck non-melanoma skin cancer 

2022

Journal Article

HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer

Mehdi, Ahmed M., Zhou, Chenhao, Turrell, Gavin, Walpole, Euan, Porceddu, Sandro, Frazer, Ian H. and Chandra, Janin (2022). HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer. Cancer Gene Therapy, 30 (4), 1-12. doi: 10.1038/s41417-022-00577-9

HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer

2022

Conference Publication

High-dimensional spatial phenotyping of cutaneous squamous cell carcinoma from immune-competent and immunocompromised patients

Kulasinghe, Arutha, Jhaveri, Niyati, Klymyshyn, Dmytro, Cheikh, Bassem Ben, Ladwa, Rahul, Liu, Howard, Cooper, Caroline, Belz, Gabrielle, Porceddu, Sandro and Braubach, Oliver (2022). High-dimensional spatial phenotyping of cutaneous squamous cell carcinoma from immune-competent and immunocompromised patients. SITC 37th Annual Meeting (SITC 2022), Boston, MA United States, 8–12 November 2022. London, United Kingdom: BMJ Group. doi: 10.1136/jitc-2022-sitc2022.0079

High-dimensional spatial phenotyping of cutaneous squamous cell carcinoma from immune-competent and immunocompromised patients

2022

Journal Article

Evolution of head and neck cutaneous squamous cell carcinoma nodal staging — an Australian perspective

Hurrell, Michael J. L., Low, Tsu-Hui, Ebrahimi, Ardalan, Veness, Michael, Ashford, Bruce, Porceddu, Sandro and Clark, Jonathan R. (2022). Evolution of head and neck cutaneous squamous cell carcinoma nodal staging — an Australian perspective. Cancers, 14 (20) 5101, 1-15. doi: 10.3390/cancers14205101

Evolution of head and neck cutaneous squamous cell carcinoma nodal staging — an Australian perspective

2022

Journal Article

A prospective observational cohort study examining the development of head and neck lymphedema from the time of diagnosis

Pigott, Amanda, Brown, Bena, White, Nicole, McPhail, Steven, Porceddu, Sandro, Liu, Howard, Jeans, Claire, Panizza, Ben and Nixon, Jodie (2022). A prospective observational cohort study examining the development of head and neck lymphedema from the time of diagnosis. Asia-Pacific Journal of Clinical Oncology, 19 (4), 473-481. doi: 10.1111/ajco.13843

A prospective observational cohort study examining the development of head and neck lymphedema from the time of diagnosis

2022

Journal Article

Epidemiology and treatment outcomes of cutaneous squamous cell carcinoma extending to the temporal bone

Schachtel, Michael J. C., Gandhi, Mitesh, Bowman, James J., Porceddu, Sandro V. and Panizza, Benedict J. (2022). Epidemiology and treatment outcomes of cutaneous squamous cell carcinoma extending to the temporal bone. Head and Neck, 44 (12), 2727-2743. doi: 10.1002/hed.27185

Epidemiology and treatment outcomes of cutaneous squamous cell carcinoma extending to the temporal bone

2022

Journal Article

Immunotherapy for the treatment of perineural spread in cutaneous head and neck squamous cell carcinoma: time to rethink treatment paradigms

Nightingale, James, Gandhi, Mitesh, Helena, Jonathan, Bowman, James, McGrath, Margaret, Coward, Jermaine, Porceddu, Sandro, Ladwa, Rahul and Panizza, Benedict (2022). Immunotherapy for the treatment of perineural spread in cutaneous head and neck squamous cell carcinoma: time to rethink treatment paradigms. Head and Neck, 44 (5), 1099-1105. doi: 10.1002/hed.27005

Immunotherapy for the treatment of perineural spread in cutaneous head and neck squamous cell carcinoma: time to rethink treatment paradigms

2022

Journal Article

Influence of Treatment Package Time on outcomes in High-Risk Oral Cavity Carcinoma in patients receiving Adjuvant Radiation and Concurrent Systemic Therapy: A Multi-Institutional Oral Cavity Collaborative study

Ghanem, Ahmed I., Woody, Neil M., Schymick, Mathew A., Joshi, Nikhil P., Geiger, Jessica L., Jillian Tsai, Chiaojung, Dunlap, Neal E., Liu, Howard Y., Burkey, Brian B., Lamarre, Eric D., Ku, Jamie A., Scharpf, Joseph, Caudell, Jimmy J., Porceddu, Sandro V., Lee, Nancy Y., Adelstein, David J., Koyfman, Shlomo A. and Siddiqui, Farzan (2022). Influence of Treatment Package Time on outcomes in High-Risk Oral Cavity Carcinoma in patients receiving Adjuvant Radiation and Concurrent Systemic Therapy: A Multi-Institutional Oral Cavity Collaborative study. Oral Oncology, 126 105781, 1-7. doi: 10.1016/j.oraloncology.2022.105781

Influence of Treatment Package Time on outcomes in High-Risk Oral Cavity Carcinoma in patients receiving Adjuvant Radiation and Concurrent Systemic Therapy: A Multi-Institutional Oral Cavity Collaborative study

2022

Journal Article

Facial nerve perineural spread from cutaneous squamous cell carcinoma of the head and neck: a single institution analysis of epidemiology, treatment, survival outcomes, and prognostic factors

Schachtel, Michael J. C., Gandhi, Mitesh, Bowman, James J., Porceddu, Sandro V. and Panizza, Benedict J. (2022). Facial nerve perineural spread from cutaneous squamous cell carcinoma of the head and neck: a single institution analysis of epidemiology, treatment, survival outcomes, and prognostic factors. Head and Neck, 44 (5), 1223-1236. doi: 10.1002/hed.27017

Facial nerve perineural spread from cutaneous squamous cell carcinoma of the head and neck: a single institution analysis of epidemiology, treatment, survival outcomes, and prognostic factors

2022

Journal Article

Prognostic stratification of HPV-associated oropharyngeal cancer based on CD103+ immune cell abundance in patients treated on TROG 12.01 and De-ESCALaTE randomized trials

Rischin, D., Mehanna, H., Young, R. J., Bressel, M., Dunn, J., Corry, J., Soni, P., Fulton-Lieuw, T., Iqbal, G., Kenny, L., Porceddu, S., Wratten, C., Robinson, M., Solomon, B. J. and on behalf of theTrans-Tasman Radiation Oncology Group and the De-ESCALaTE HPV Trial Group (2022). Prognostic stratification of HPV-associated oropharyngeal cancer based on CD103+ immune cell abundance in patients treated on TROG 12.01 and De-ESCALaTE randomized trials. Annals of Oncology, 33 (8), 804-813. doi: 10.1016/j.annonc.2022.04.074

Prognostic stratification of HPV-associated oropharyngeal cancer based on CD103+ immune cell abundance in patients treated on TROG 12.01 and De-ESCALaTE randomized trials

Funding

Past funding

  • 2019 - 2020
    Head and neck lymphoedema treatment: An examination and development of current standards of care
    PA Research Foundation
    Open grant
  • 2013 - 2016
    Can a computerised home therapy program provide an effective and cost-efficient model for delivering intensive swallowing therapy? An RTC of an innovative service model...
    Princess Alexandra Hospital
    Open grant
  • 2013 - 2015
    The role of epidermal growth factor receptor trafficking in tumor progression and patient therapy resistance
    Cancer Council Queensland
    Open grant
  • 2007 - 2011
    Post-operative concurrent chemo-radiotherapy versus post-operative radiotheray in high-risk cutaneous squamous cell carcinoma of the head and neck
    Queensland Health Smart Health Research Grant
    Open grant

Supervision

Availability

Professor Sandro Porceddu is:
Available for supervision

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Media

Enquiries

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communications@uq.edu.au