
Overview
Background
Profile Summary
Dr Sandro Porceddu is an internationally recognised radiation oncologist and a leading authority in head and neck and skin cancer. With over 20 years experience in medicine his areas of clinical expertise include head and neck cancer, skin cancer, sarcoma and lymphoma. He is currently a senior radiation oncologist and Director of radiation oncology research at the Princess Alexandra Hospital, Brisbane, Professor of Medicine, University of Queensland and Associate Editor for the International Head and Neck journal, Oral Oncology.
Dr Porceddu is a nationally and internationally recognised cancer advocate through his involvement in high-level committees, engagement with key policymakers, community education and media roles.
Career Summary
Professor Porceddu completed his medical degree at Monash University before undertaking his residency at Monash Medical Centre, Melbourne. He commenced his specialist training in radiation oncology at the Peter MacCallum Cancer Centre in 1996 and was made Fellow of the Royal Australian and New Zealand College of Radiologists, Faculty of Radiation Oncology in 2000. After working as a consultant radiation oncologist at PeterMac for several years he moved to the Princess Alexandra Hospital in 2004.
Professional Committees and Organisations
Professor Porceddu has been the President of the Clinical Oncology Society of Australia (COSA), the peak organisation for cancer-related health professionals, and the Trans Tasman Radiation Oncology Group (TROG), one of the largest cancer collaborative trials group in Australia/New Zealand. He has served on numerous national and international professional and academic committees including the board of the Cancer Council of Australia, the National Cancer Expert Reference Group for the Commonwealth and the International Union for the Control of Cancer (UICC) TNM Expert Advisory Panel.
Currently, he is the Chair of the Cancer Council Queensland Co-operative Oncology Group, a committee that provides over $1.2M per annum to support clinical research throughout Queensland and is on the board of the of the Head and Neck Cancer InterGroup (HNCIG), a group of leading world cancer experts dedicated to promoting the global harmonisation of head and neck cancer research and treatment.
Academic Highlights
Professor Porceddu runs an active clinical research program with over 150 peer-review articles, book chapters, published abstracts, invited reviews and commentaries. He has received invitations to speak at major international conferences such as the American Society of Clinical Oncology (ASCO) meeting and publish in prestigious journals such as the Lancet Oncology and Journal of Clinical Oncology.
Awards
Trans Tasman Radiation Oncology Group Outstanding Contribution
American Head and Neck Society Chris O’Brien Travelling Scholar
Pre-eminent status by Queensland Health
Rouse Fellowship, Royal Australian and New Zealand College of Radiologists
Teaching
Dr Porceddu has had a life-long commitment to teaching and is a supervisor and mentor to Doctor of Philosophy and Master of Philosophy candidates, Clinical Research Fellows, MBBS Honours students, resident, registrars and other allied health professionals.
Availability
- Professor Sandro Porceddu is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Science, Monash University
- Bachelor of Medicine and Surgery and Medical Science, Monash University
- Doctoral Diploma of Medicine, The University of Queensland
Research impacts
Dr Porceddu’s has been investigating methods to reduce the morbidity of treatment, improve cure rates and quality of life for cancer patients. He runs an active head and neck/skin cancer research program and is the principal investigator of numerous trials including an NHMRC-supported Randomised Phase III trial on head and neck skin cancer (POST TROG 05.01). In line with his research goals he has been examining the integration of radiation therapy and new technologies in the management of head and neck cancer and has received his Doctorate of Medicine (MD) on this topic with UQ. His current research on Positron Emission Tomography in the management of the neck following chemo-radiotherapy has been internationally recognised and incorporated into the USA National Comprehensive Cancer Network (NCCN) guidelines. He has been the recipient of over $3.91M in competitive funding, including one recently closed and two open NHMRC grants.
Works
Search Professor Sandro Porceddu’s works on UQ eSpace
2022
Journal Article
Patient- and Clinician-Reported Outcomes in Human Papillomavirus-Associated Tonsillar Carcinoma Treated With Unilateral and Bilateral Intensity Modulated Radiation Therapy–A Substudy From TROG12.01
McDowell, Lachlan, Rischin, Danny, King, Madeleine, Kenny, Lizbeth, Porceddu, Sandro, Wratten, Christopher, Macann, Andrew, Jackson, James E., Bressel, Mathias, Fua, Tsien, Lin, Charles, Liu, Chen and Corry, June (2022). Patient- and Clinician-Reported Outcomes in Human Papillomavirus-Associated Tonsillar Carcinoma Treated With Unilateral and Bilateral Intensity Modulated Radiation Therapy–A Substudy From TROG12.01. International Journal of Radiation Oncology Biology Physics, 115 (1), 174-188. doi: 10.1016/j.ijrobp.2022.08.006
2022
Journal Article
Prognostic stratification of HPV-associated oropharyngeal cancer based on CD103+ immune cell abundance in patients treated on TROG 12.01 and De-ESCALaTE randomized trials
Rischin, D., Mehanna, H., Young, R. J., Bressel, M., Dunn, J., Corry, J., Soni, P., Fulton-Lieuw, T., Iqbal, G., Kenny, L., Porceddu, S., Wratten, C., Robinson, M., Solomon, B. J. and on behalf of theTrans-Tasman Radiation Oncology Group and the De-ESCALaTE HPV Trial Group (2022). Prognostic stratification of HPV-associated oropharyngeal cancer based on CD103+ immune cell abundance in patients treated on TROG 12.01 and De-ESCALaTE randomized trials. Annals of Oncology, 33 (8), 804-813. doi: 10.1016/j.annonc.2022.04.074
2021
Journal Article
Complete response to PD-1 blockade following EBV-specific T-cell therapy in metastatic nasopharyngeal carcinoma
Smith, Corey, McGrath, Margaret, Neller, Michelle A., Matthews, Katherine K., Crooks, Pauline, Le Texier, Laetitia, Panizza, Benedict, Porceddu, Sandro and Khanna, Rajiv (2021). Complete response to PD-1 blockade following EBV-specific T-cell therapy in metastatic nasopharyngeal carcinoma. npj Precision Oncology, 5 (1) 24, 24. doi: 10.1038/s41698-021-00162-7
2021
Journal Article
Randomized trial of radiation therapy with weekly cisplatin or cetuximab in low-risk HPV-associated oropharyngeal cancer (TROG 12.01) – A Trans-Tasman Radiation Oncology Group Study
Rischin, Danny, King, Madeleine, Kenny, Lizbeth, Porceddu, Sandro, Wratten, Christopher, Macann, Andrew, Jackson, James E., Bressel, Mathias, Herschtal, Alan, Fisher, Richard, Fua, Tsien, Lin, Charles, Liu, Chen, Hughes, Brett G.M., McGrath, Margaret, McDowell, Lachlan and Corry, June (2021). Randomized trial of radiation therapy with weekly cisplatin or cetuximab in low-risk HPV-associated oropharyngeal cancer (TROG 12.01) – A Trans-Tasman Radiation Oncology Group Study. International Journal of Radiation: Oncology - Biology - Physics, 111 (4), 876-886. doi: 10.1016/j.ijrobp.2021.04.015
2021
Journal Article
Clinician perspectives on the factors influencing prognostic stratification by the American Joint Commission on Cancer Head and Neck Cutaneous Squamous Cell Carcinoma Staging
Watts, Francesca, Palme, Carsten E., Porceddu, Sandro, Sundaresan, Purnima, Clark, Jonathan R. and Gupta, Ruta (2021). Clinician perspectives on the factors influencing prognostic stratification by the American Joint Commission on Cancer Head and Neck Cutaneous Squamous Cell Carcinoma Staging. Surgery, 170 (5), 1467-1473. doi: 10.1016/j.surg.2021.04.019
2021
Journal Article
Malignancies requiring temporal bone resection: an Australian single‐institution experience
Schachtel, Michael J. C., Gandhi, Mitesh, Bowman, James J., Erian, Christopher, Porceddu, Sandro V. and Panizza, Benedict J. (2021). Malignancies requiring temporal bone resection: an Australian single‐institution experience. ANZ Journal of Surgery, 91 (7-8) ans.16931, 1462-1471. doi: 10.1111/ans.16931
2021
Journal Article
Exploring the interplay between radiotherapy dose and physiological changes in the swallowing mechanism in patients undergoing (chemo)radiotherapy for oropharynx cancer
Hutchison, Alana R., Wishart, Laurelie R., Brown, Bena, Ward, Elizabeth C., Hargrave, Catriona, Brown, Elizabeth and Porceddu, Sandro (2021). Exploring the interplay between radiotherapy dose and physiological changes in the swallowing mechanism in patients undergoing (chemo)radiotherapy for oropharynx cancer. Dysphagia, 37 (3), 567-577. doi: 10.1007/s00455-021-10307-2
2021
Journal Article
The hidden curve behind COVID-19 outbreak: the impact of delay in treatment initiation in cancer patients and how to mitigate the additional risk of dying—the head and neck cancer model
Matos, Leandro L., Forster, Carlos Henrique Q., Marta, Gustavo N., Castro Junior, Gilberto, Ridge, John A., Hirata, Daisy, Miranda-Filho, Adalberto, Hosny, Ali, Sanabria, Alvaro, Gregoire, Vincent, Patel, Snehal G., Fagan, Johannes J., D’Cruz, Anil K., Licitra, Lisa, Mehanna, Hisham, Hao, Sheng-Po, Psyrri, Amanda, Porceddu, Sandro, Galloway, Thomas J., Golusinski, Wojciech, Lee, Nancy Y., Shiguemori, Elcio H., Matieli, José Elias, Shiguemori, Ana Paula A. C., Diamantino, Letícia R., Schiaveto, Luiz Felipe, Leão, Lysia, Castro, Ana F., Carvalho, André Lopes and Kowalski, Luiz Paulo (2021). The hidden curve behind COVID-19 outbreak: the impact of delay in treatment initiation in cancer patients and how to mitigate the additional risk of dying—the head and neck cancer model. Cancer Causes and Control, 32 (5), 459-471. doi: 10.1007/s10552-021-01411-7
2021
Journal Article
The importance of smoking status at diagnosis in human papillomavirus-associated oropharyngeal cancer
Liu, Howard Yu-hao, Daniels, Christopher P., Trada, Yuvnik, Bernard, Anne, You, Kyung Ha, Brown, Elizabeth, Foote, Matthew, McGrath, Margaret, Ladwa, Rahul, Panizza, Benedict James and Porceddu, Sandro Virgilio (2021). The importance of smoking status at diagnosis in human papillomavirus-associated oropharyngeal cancer. Head and Neck, 43 (5), 1440-1450. doi: 10.1002/hed.26612
2021
Journal Article
Indications and limits of postoperative radiotherapy for skin malignancies
Daniels, Christopher P., Liu, Howard Y-H and Porceddu, Sandro V. (2021). Indications and limits of postoperative radiotherapy for skin malignancies. Current opinion in otolaryngology & head and neck surgery, 29 (2), 100-106. doi: 10.1097/MOO.0000000000000696
2021
Journal Article
Failure rate in the untreated contralateral node negative neck of small lateralized oral cavity cancers: a multi-institutional collaborative study
Liu, Howard Yu-hao, Tam, Laura, Woody, Neil M., Caudell, Jimmy, Reddy, Chandana A., Ghanem, Ahmed, Schymick, Matthew, Joshi, Nikhil, Geiger, Jessica, Lamarre, Eric, Burkey, Brian, Adelstein, David, Dunlap, Neal, Siddiqui, Farzan, Koyfman, Shlomo and Porceddu, Sandro Virgilio (2021). Failure rate in the untreated contralateral node negative neck of small lateralized oral cavity cancers: a multi-institutional collaborative study. Oral Oncology, 115 105190, 105190. doi: 10.1016/j.oraloncology.2021.105190
2020
Journal Article
Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer
Dhawan, Andrew, Scott, Jacob, Sundaresan, Purnima, Veness, Michael, Porceddu, Sandro, Hau, Eric, Harris, Adrian L., Buffa, Francesca M. and Gee, Harriet E. (2020). Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer. Scientific Reports, 10 (1) 10226, 1-10. doi: 10.1038/s41598-020-66983-x
2020
Journal Article
Number of nodal metastases and the American Joint Committee on cancer staging of head and neck cutaneous squamous cell carcinoma: a multicenter study
Ebrahimi, Ardalan, Gupta, Ruta, Luk, Peter, Low, Tsu-Hui (Hubert), McDowell, Lachlan, Magarey, Matthew J.R., Smith, Paul N., Perriman, Diana M., Schulte, Klaus-Martin, Veness, Michael, Porceddu, Sandro V. and Clark, Jonathan R. (2020). Number of nodal metastases and the American Joint Committee on cancer staging of head and neck cutaneous squamous cell carcinoma: a multicenter study. Oral Oncology, 111 104855, 104855. doi: 10.1016/j.oraloncology.2020.104855
2020
Journal Article
Therapeutic implications of immune-profiling and EGFR expression in salivary gland carcinoma
Guazzo, Emily, Cooper, Caroline, Wilkinson, Lisa, Feng, Sophie, King, Brigid, Simpson, Fiona, Porceddu, Sandro, Panizza, Benedict and Coward, Jermaine I G (2020). Therapeutic implications of immune-profiling and EGFR expression in salivary gland carcinoma. Head and neck, 43 (3) hed.26529, 768-777. doi: 10.1002/hed.26529
2020
Journal Article
Validation of local p16 testing for determination of human papilloma virus status eligibility on a low risk oropharyngeal cancer trial – A Trans-Tasman Radiation Oncology Group study
Young, Richard J., Solomon, Benjamin, Corry, June, Angel, Christopher, Kenny, Lizbeth, Porceddu, Sandro, Wratten, Christopher, Macann, Andrew, Jackson, James E., Herschtal, Alan and Rischin, Danny (2020). Validation of local p16 testing for determination of human papilloma virus status eligibility on a low risk oropharyngeal cancer trial – A Trans-Tasman Radiation Oncology Group study. Oral Oncology, 110 104988, 104988. doi: 10.1016/j.oraloncology.2020.104988
2020
Journal Article
The declining role of post-treatment neck dissection in human papillomavirus-associated oropharyngeal cancer
Daniels, Christopher P., Liu, Howard Yu-hao, Bernard, Anne, Williams, Christopher, Foote, Matthew C., Ladwa, Rahul, McGrath, Margaret, Panizza, Benedict James and Porceddu, Sandro Virgilio (2020). The declining role of post-treatment neck dissection in human papillomavirus-associated oropharyngeal cancer. Radiotherapy and Oncology, 151, 242-248. doi: 10.1016/j.radonc.2020.08.004
2020
Journal Article
Practice recommendations for risk-adapted head and neck cancer radiotherapy during the COVID-19 pandemic: An ASTRO-ESTRO consensus statement
Thomson, David J., Palma, David, Guckenberger, Matthias, Balermpas, Panagiotis, Beitler, Jonathan J., Blanchard, Pierre, Brizel, David, Budach, Wilfred, Caudell, Jimmy, Corry, June, Corvo, Renzo, Evans, Mererid, Garden, Adam S., Giralt, Jordi, Gregoire, Vincent, Harari, Paul M., Harrington, Kevin, Hitchcock, Ying J., Johansen, Jorgen, Kaanders, Johannes, Koyfman, Shlomo, Langendijk, J. A., Le, Quynh-Thu, Lee, Nancy, Margalit, Danielle, Mierzwa, Michelle, Porceddu, Sandro, Soong, Yoke Lim, Sun, Ying ... Yom, Sue S. (2020). Practice recommendations for risk-adapted head and neck cancer radiotherapy during the COVID-19 pandemic: An ASTRO-ESTRO consensus statement. Radiotherapy and Oncology, 151, 314-321. doi: 10.1016/j.radonc.2020.04.019
2020
Journal Article
A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC)
Chandra, J., Woo, W. P., Finlayson, N., Liu, H. Y., McGrath, M., Ladwa, R., Brauer, M., Xu, Y., Hanson, S., Panizza, B., Frazer, I. H. and Porceddu, Sandro V. (2020). A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC). Cancer Immunology, Immunotherapy, 70 (3), 743-753. doi: 10.1007/s00262-020-02720-7
2020
Journal Article
De-Escalation After DE-ESCALATE and RTOG 1016: A Head and Neck Cancer InterGroup Framework for Future De-Escalation Studies
Mehanna, Hisham, Rischin, Danny, Wong, Stuart J., Gregoire, Vincent, Ferris, Robert, Waldron, John, Le, Quynh-Thu, Forster, Martin, Gillison, Maura, Laskar, Sarbani, Tahara, Makoto, Psyrri, Amanda, Vermorken, Jan and Porceddu, Sandro (2020). De-Escalation After DE-ESCALATE and RTOG 1016: A Head and Neck Cancer InterGroup Framework for Future De-Escalation Studies. Journal of Clinical Oncology, 38 (22), 2552-2557. doi: 10.1200/JCO.20.00056
2020
Journal Article
Adapting Head and Neck Cancer Management in the Time of COVID-19
Mehanna, Hisham, Gillison, Maura, Lee, Anne W.M., von Zeidler, Sandra V., Porceddu, Sandro and on behalf ofthe Head and Neck International Group (HNCIG) (2020). Adapting Head and Neck Cancer Management in the Time of COVID-19. International Journal of Radiation Oncology Biology Physics, 107 (4), 628-630. doi: 10.1016/j.ijrobp.2020.04.017
Funding
Past funding
Supervision
Availability
- Professor Sandro Porceddu is:
- Available for supervision
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Supervision history
Completed supervision
-
2017
Master Philosophy
Pre-radiotherapy dental extractions and osteoradionecrosis: a retrospective analysis and cross-sectional study on quality of life
Associate Advisor
-
2012
Doctor Philosophy
Swallowing, nutrition, and patient-rated functional outcomes in head and neck cancer patients treated with altered fractionation radiotherapy
Associate Advisor
Other advisors: Professor Elizabeth Ward
Media
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