Overview
Background
As an evolutionary quantitative geneticist, I conduct research that aims to extend our understanding of how genetic variation determines the capacity of populations to adapt. Over the 20+ years of my research career, I have designed experiments in species ranging from freshwater fish to Drosophila fruit flies. My research group uses a combination of statistics and machine learning to answer questions about the nature of genetic variation in complex traits, like swimming speed, wing shape and sex pheromones. This fundamental knowledge underpins predictions of the rate at which individual traits within the complex, multi-trait phenotype of organisms can evolve. We are particularly interested in understanding how historical adaptation might affect the ability of populations to adapt to changing conditions now and into the future. I’m interested in bringing evolutionary quantitative genetic tools to answer questions about natural and manipulated evolution in non-model species, in complex natural environments. I am passionate about training researchers in genetics and statistics, foundational skills for a range of careers addressing both applied and fundamental questions. I teach these skills to undergraduate and coursework Masters students, as well as research students ranging from undergraduate projects, through Honours and PhD.
Availability
- Associate Professor Katrina McGuigan is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Works
Search Professor Katrina McGuigan’s works on UQ eSpace
Featured
2023
Journal Article
Using inbreeding to test the contribution of non-additive genetic effects to additive genetic variance: a case study in Drosophila serrata
Dugand, Robert J., Blows, Mark W. and McGuigan, Katrina (2023). Using inbreeding to test the contribution of non-additive genetic effects to additive genetic variance: a case study in Drosophila serrata. Proceedings of the Royal Society B: Biological Sciences, 290 (1995) 20222111, 1-10. doi: 10.1098/rspb.2022.2111
Featured
2022
Journal Article
Causes of variability in estimates of mutational variance from mutation accumulation experiments
Conradsen, Cara, Blows, Mark W and McGuigan, Katrina (2022). Causes of variability in estimates of mutational variance from mutation accumulation experiments. Genetics, 221 (2) iyac060, 1-14. doi: 10.1093/genetics/iyac060
Featured
2021
Journal Article
The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata
Dugand, Robert J., Aguirre, J. David, Hine, Emma, Blows, Mark W. and McGuigan, Katrina (2021). The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata. Proceedings of the National Academy of Sciences, 118 (31) e2026217118, 1-10. doi: 10.1073/pnas.2026217118
Featured
2021
Journal Article
How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?
McGuigan, Katrina, Hoffmann, Ary A. and Sgrò, Carla M. (2021). How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?. Philosophical Transactions of the Royal Society B: Biological Sciences, 376 (1826) 20200119, 1-10. doi: 10.1098/rstb.2020.0119
Featured
2014
Journal Article
Pleiotropic mutations are subject to strong stabilizing selection
McGuigan, Katrina, Collet, Julie M., Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2014). Pleiotropic mutations are subject to strong stabilizing selection. Genetics, 197 (3), 1051-1062. doi: 10.1534/genetics.114.165720
Featured
2014
Journal Article
The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata
McGuigan, Katrina, Collet, Julie M., McGraw, Elizabeth A., Ye, Yixin H., Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2014). The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata. Genetics, 196 (3), 911-921. doi: 10.1534/genetics.114.161232
Featured
2013
Journal Article
Joint allelic effects on fitness and metric traits
McGuigan, Katrina and Blows, Mark W. (2013). Joint allelic effects on fitness and metric traits. Evolution, 67 (4), 1131-1142. doi: 10.1111/j.1558-5646.2012.01833.x
Featured
2011
Journal Article
Cryptic genetic variation and body size evolution in threespine stickleback
McGuigan, Katrina, Nishimura, Nicole, Currey, Mark, Hurwit, Dan and Cresko, William A. (2011). Cryptic genetic variation and body size evolution in threespine stickleback. Evolution, 65 (4), 1203-1211. doi: 10.1111/j.1558-5646.2010.01195.x
Featured
2009
Journal Article
Evolutionary consequences of cryptic genetic variation
McGuigan, K.L. and Sgro, C.M. (2009). Evolutionary consequences of cryptic genetic variation. Trends in Ecology & Evolution, 24 (6), 305-311. doi: 10.1016/j.tree.2009.02.001
Featured
2003
Journal Article
Adaptation of rainbow fish to lake and stream habitats
McGuigan, Katrina, Franklin, Craig E., Moritz, Craig and Blows, Mark W. (2003). Adaptation of rainbow fish to lake and stream habitats. Evolution, 57 (1), 104-118. doi: 10.1554/0014-3820(2003)057[0104:AORFTL]2.0.CO;2
2024
Journal Article
Effects of spontaneous mutations on survival and reproduction of <i>Drosophila serrata</i> infected with Drosophila C virus
Mendel, Bonita M, Asselin, Angelique K, Johnson, Karyn N and McGuigan, Katrina (2024). Effects of spontaneous mutations on survival and reproduction of Drosophila serrata infected with Drosophila C virus. Evolution, 78 (10), 1661-1672. doi: 10.1093/evolut/qpae101
2024
Journal Article
Variability of morphology-performance relationships under acute exposure to different temperatures in three strains of zebrafish
Miller, Christina L, Dugand, Robert and McGuigan, Katrina (2024). Variability of morphology-performance relationships under acute exposure to different temperatures in three strains of zebrafish. Current Zoology. doi: 10.1093/cz/zoae032
2024
Other Outputs
Drosophila serrata MA immune function
McGuigan, Katrina (2024). Drosophila serrata MA immune function. The University of Queensland. (Dataset) doi: 10.48610/48d7c29
2023
Journal Article
Environmental dependence of mutational (co)variances of adaptive traits
Kannan, Ashvitha, Dugand, Robert J., Appleton, Nicholas C., Chenoweth, Stephen F., Sgrò, Carla M. and McGuigan, Katrina (2023). Environmental dependence of mutational (co)variances of adaptive traits. Evolution, 77 (11), 2341-2351. doi: 10.1093/evolut/qpad154
2023
Journal Article
The contribution of mutation to variation in temperature-dependent sprint speed in zebrafish, Danio rerio
Miller, Christina L., Sun, Derek, Thornton, Lauren H. and McGuigan, Katrina (2023). The contribution of mutation to variation in temperature-dependent sprint speed in zebrafish, Danio rerio. American Naturalist, 202 (4), 519-533. doi: 10.1086/726011
2023
Journal Article
Predicting the future
Walter, Greg M and McGuigan, Katrina (2023). Predicting the future. eLife, 12 e91450. doi: 10.7554/elife.91450
2023
Journal Article
Moving beyond heritability in the search for coral adaptive potential
Richards, Thomas J., McGuigan, Katrina, Aguirre, J. David, Humanes, Adriana, Bozec, Yves‐Marie, Mumby, Peter J. and Riginos, Cynthia (2023). Moving beyond heritability in the search for coral adaptive potential. Global Change Biology, 29 (14), 3869-3882. doi: 10.1111/gcb.16719
2023
Other Outputs
MxE_Drosophila serrata
McGuigan, Katrina and Dugand, Robert (2023). MxE_Drosophila serrata. The University of Queensland. (Dataset) doi: 10.48610/01993ca
2023
Other Outputs
Zebrafish Ucrit and Morphology
McGuigan, Katrina and Miller, Christina (2023). Zebrafish Ucrit and Morphology. The University of Queensland. (Dataset) doi: 10.48610/2a7ddb6
2022
Journal Article
Maintenance of quantitative genetic variance in complex, multitrait phenotypes: the contribution of rare, large effect variants in 2 Drosophila species
Hine, Emma, Runcie, Daniel E., Allen, Scott L., Wang, Yiguan, Chenoweth, Stephen F., Blows, Mark W. and McGuigan, Katrina (2022). Maintenance of quantitative genetic variance in complex, multitrait phenotypes: the contribution of rare, large effect variants in 2 Drosophila species. Genetics, 222 (2) iyac122, 1-17. doi: 10.1093/genetics/iyac122
Funding
Past funding
Supervision
Availability
- Associate Professor Katrina McGuigan is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Context dependence of new mutations: the role of ancestral alleles and sex.
Principal Advisor
Other advisors: Professor Steve Chenoweth, Dr Masato Yamamichi
-
Doctor Philosophy
Applications of novel models of multivariate trait evolution in marsupials
Associate Advisor
Other advisors: Associate Professor Lyn Cook, Dr Simone Blomberg
-
Doctor Philosophy
Applications of novel models of multivariate trait evolution in marsupials
Associate Advisor
Other advisors: Associate Professor Lyn Cook, Dr Simone Blomberg
-
Doctor Philosophy
Estimating disease susceptibility to fungal pathogen in animals
Associate Advisor
Other advisors: Associate Professor Celine Frere
-
Doctor Philosophy
Some like it hot: invasive species, hybridisation, and a warming world
Associate Advisor
Other advisors: Professor Cynthia Riginos
-
Doctor Philosophy
Unification of selection and inheritance informs adaptive potential for generations to come
Associate Advisor
Other advisors: Professor Mark Cooper, Dr Yang Liu
Completed supervision
-
2023
Doctor Philosophy
The contribution of new mutations to genetic variation of quantitative traits
Principal Advisor
Other advisors: Professor Mark Blows, Professor Steve Chenoweth
-
2023
Doctor Philosophy
Determining the Genetic and Mutational Contributions to a Complex, Environmentally Dependent, Phenotype
Principal Advisor
Other advisors: Professor Craig Franklin
-
2023
Doctor Philosophy
The Relationships Between Dietary Macronutrients and Ageing
Associate Advisor
Other advisors: Professor Steve Chenoweth
-
2021
Master Philosophy
The impacts of mutation and selection on sex-biased gene expression in Drosophila serrata
Associate Advisor
Other advisors: Professor Steve Chenoweth
-
2020
Doctor Philosophy
Seeing and responding to colour signals: an investigation using coral reef fish
Associate Advisor
Other advisors: Associate Professor Karen Cheney
-
2019
Doctor Philosophy
Dimensions of genotypic and phenotypic divergence in marine metapopulations: space, time, and ontogeny
Associate Advisor
Other advisors: Professor Cynthia Riginos
-
2017
Doctor Philosophy
Response to natural selection in Senecio Lautus
Associate Advisor
Other advisors: Professor Daniel Ortiz-Barrientos
-
2016
Doctor Philosophy
Stabilizing selection and the evolution of genetic variance in multivariate traits in Drosophila serrata
Associate Advisor
Other advisors: Professor Steve Chenoweth, Professor Mark Blows
-
2010
Doctor Philosophy
Mutation-selection balance and the evolution of genetic variance in multiple male sexually-selected pheromones of the vinegar fly Drosophila serrata
Associate Advisor
Other advisors: Professor Mark Blows
Media
Enquiries
For media enquiries about Associate Professor Katrina McGuigan's areas of expertise, story ideas and help finding experts, contact our Media team: