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Associate Professor Katrina McGuigan
Associate Professor

Katrina McGuigan

Email: 
Phone: 
+61 7 336 52855

Overview

Background

As an evolutionary quantitative geneticist, I conduct research that aims to extend our understanding of how genetic variation determines the capacity of populations to adapt. Over the 20+ years of my research career, I have designed experiments in species ranging from freshwater fish to Drosophila fruit flies. My research group uses a combination of statistics and machine learning to answer questions about the nature of genetic variation in complex traits, like swimming speed, wing shape and sex pheromones. This fundamental knowledge underpins predictions of the rate at which individual traits within the complex, multi-trait phenotype of organisms can evolve. We are particularly interested in understanding how historical adaptation might affect the ability of populations to adapt to changing conditions now and into the future. I’m interested in bringing evolutionary quantitative genetic tools to answer questions about natural and manipulated evolution in non-model species, in complex natural environments. I am passionate about training researchers in genetics and statistics, foundational skills for a range of careers addressing both applied and fundamental questions. I teach these skills to undergraduate and coursework Masters students, as well as research students ranging from undergraduate projects, through Honours and PhD.

Availability

Associate Professor Katrina McGuigan is:
Available for supervision

Fields of research

Qualifications

  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Works

Search Professor Katrina McGuigan’s works on UQ eSpace

71 works between 1998 and 2024

1 - 20 of 71 works

Featured

2023

Journal Article

Using inbreeding to test the contribution of non-additive genetic effects to additive genetic variance: a case study in Drosophila serrata

Dugand, Robert J., Blows, Mark W. and McGuigan, Katrina (2023). Using inbreeding to test the contribution of non-additive genetic effects to additive genetic variance: a case study in Drosophila serrata. Proceedings of the Royal Society B: Biological Sciences, 290 (1995) 20222111, 1-10. doi: 10.1098/rspb.2022.2111

Using inbreeding to test the contribution of non-additive genetic effects to additive genetic variance: a case study in Drosophila serrata

Featured

2022

Journal Article

Causes of variability in estimates of mutational variance from mutation accumulation experiments

Conradsen, Cara, Blows, Mark W and McGuigan, Katrina (2022). Causes of variability in estimates of mutational variance from mutation accumulation experiments. Genetics, 221 (2) iyac060, 1-14. doi: 10.1093/genetics/iyac060

Causes of variability in estimates of mutational variance from mutation accumulation experiments

Featured

2021

Journal Article

The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata

Dugand, Robert J., Aguirre, J. David, Hine, Emma, Blows, Mark W. and McGuigan, Katrina (2021). The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata. Proceedings of the National Academy of Sciences, 118 (31) e2026217118, 1-10. doi: 10.1073/pnas.2026217118

The contribution of mutation and selection to multivariate quantitative genetic variance in an outbred population of Drosophila serrata

Featured

2021

Journal Article

How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?

McGuigan, Katrina, Hoffmann, Ary A. and Sgrò, Carla M. (2021). How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?. Philosophical Transactions of the Royal Society B: Biological Sciences, 376 (1826) 20200119, 1-10. doi: 10.1098/rstb.2020.0119

How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?

Featured

2014

Journal Article

Pleiotropic mutations are subject to strong stabilizing selection

McGuigan, Katrina, Collet, Julie M., Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2014). Pleiotropic mutations are subject to strong stabilizing selection. Genetics, 197 (3), 1051-1062. doi: 10.1534/genetics.114.165720

Pleiotropic mutations are subject to strong stabilizing selection

Featured

2014

Journal Article

The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata

McGuigan, Katrina, Collet, Julie M., McGraw, Elizabeth A., Ye, Yixin H., Allen, Scott L., Chenoweth, Stephen F. and Blows, Mark W. (2014). The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata. Genetics, 196 (3), 911-921. doi: 10.1534/genetics.114.161232

The nature and extent of mutational pleiotropy in gene expression of male Drosophila serrata

Featured

2013

Journal Article

Joint allelic effects on fitness and metric traits

McGuigan, Katrina and Blows, Mark W. (2013). Joint allelic effects on fitness and metric traits. Evolution, 67 (4), 1131-1142. doi: 10.1111/j.1558-5646.2012.01833.x

Joint allelic effects on fitness and metric traits

Featured

2011

Journal Article

Cryptic genetic variation and body size evolution in threespine stickleback

McGuigan, Katrina, Nishimura, Nicole, Currey, Mark, Hurwit, Dan and Cresko, William A. (2011). Cryptic genetic variation and body size evolution in threespine stickleback. Evolution, 65 (4), 1203-1211. doi: 10.1111/j.1558-5646.2010.01195.x

Cryptic genetic variation and body size evolution in threespine stickleback

Featured

2009

Journal Article

Evolutionary consequences of cryptic genetic variation

McGuigan, K.L. and Sgro, C.M. (2009). Evolutionary consequences of cryptic genetic variation. Trends in Ecology & Evolution, 24 (6), 305-311. doi: 10.1016/j.tree.2009.02.001

Evolutionary consequences of cryptic genetic variation

Featured

2003

Journal Article

Adaptation of rainbow fish to lake and stream habitats

McGuigan, Katrina, Franklin, Craig E., Moritz, Craig and Blows, Mark W. (2003). Adaptation of rainbow fish to lake and stream habitats. Evolution, 57 (1), 104-118. doi: 10.1554/0014-3820(2003)057[0104:AORFTL]2.0.CO;2

Adaptation of rainbow fish to lake and stream habitats

2024

Journal Article

Effects of spontaneous mutations on survival and reproduction of <i>Drosophila serrata</i> infected with Drosophila C virus

Mendel, Bonita M, Asselin, Angelique K, Johnson, Karyn N and McGuigan, Katrina (2024). Effects of spontaneous mutations on survival and reproduction of Drosophila serrata infected with Drosophila C virus. Evolution, 78 (10), 1661-1672. doi: 10.1093/evolut/qpae101

Effects of spontaneous mutations on survival and reproduction of <i>Drosophila serrata</i> infected with Drosophila C virus

2024

Journal Article

Variability of morphology-performance relationships under acute exposure to different temperatures in three strains of zebrafish

Miller, Christina L, Dugand, Robert and McGuigan, Katrina (2024). Variability of morphology-performance relationships under acute exposure to different temperatures in three strains of zebrafish. Current Zoology. doi: 10.1093/cz/zoae032

Variability of morphology-performance relationships under acute exposure to different temperatures in three strains of zebrafish

2024

Other Outputs

Drosophila serrata MA immune function

McGuigan, Katrina (2024). Drosophila serrata MA immune function. The University of Queensland. (Dataset) doi: 10.48610/48d7c29

Drosophila serrata MA immune function

2023

Journal Article

Environmental dependence of mutational (co)variances of adaptive traits

Kannan, Ashvitha, Dugand, Robert J., Appleton, Nicholas C., Chenoweth, Stephen F., Sgrò, Carla M. and McGuigan, Katrina (2023). Environmental dependence of mutational (co)variances of adaptive traits. Evolution, 77 (11), 2341-2351. doi: 10.1093/evolut/qpad154

Environmental dependence of mutational (co)variances of adaptive traits

2023

Journal Article

The contribution of mutation to variation in temperature-dependent sprint speed in zebrafish, Danio rerio

Miller, Christina L., Sun, Derek, Thornton, Lauren H. and McGuigan, Katrina (2023). The contribution of mutation to variation in temperature-dependent sprint speed in zebrafish, Danio rerio. American Naturalist, 202 (4), 519-533. doi: 10.1086/726011

The contribution of mutation to variation in temperature-dependent sprint speed in zebrafish, Danio rerio

2023

Journal Article

Predicting the future

Walter, Greg M and McGuigan, Katrina (2023). Predicting the future. eLife, 12 e91450. doi: 10.7554/elife.91450

Predicting the future

2023

Journal Article

Moving beyond heritability in the search for coral adaptive potential

Richards, Thomas J., McGuigan, Katrina, Aguirre, J. David, Humanes, Adriana, Bozec, Yves‐Marie, Mumby, Peter J. and Riginos, Cynthia (2023). Moving beyond heritability in the search for coral adaptive potential. Global Change Biology, 29 (14), 3869-3882. doi: 10.1111/gcb.16719

Moving beyond heritability in the search for coral adaptive potential

2023

Other Outputs

MxE_Drosophila serrata

McGuigan, Katrina and Dugand, Robert (2023). MxE_Drosophila serrata. The University of Queensland. (Dataset) doi: 10.48610/01993ca

MxE_Drosophila serrata

2023

Other Outputs

Zebrafish Ucrit and Morphology

McGuigan, Katrina and Miller, Christina (2023). Zebrafish Ucrit and Morphology. The University of Queensland. (Dataset) doi: 10.48610/2a7ddb6

Zebrafish Ucrit and Morphology

2022

Journal Article

Maintenance of quantitative genetic variance in complex, multitrait phenotypes: the contribution of rare, large effect variants in 2 Drosophila species

Hine, Emma, Runcie, Daniel E., Allen, Scott L., Wang, Yiguan, Chenoweth, Stephen F., Blows, Mark W. and McGuigan, Katrina (2022). Maintenance of quantitative genetic variance in complex, multitrait phenotypes: the contribution of rare, large effect variants in 2 Drosophila species. Genetics, 222 (2) iyac122, 1-17. doi: 10.1093/genetics/iyac122

Maintenance of quantitative genetic variance in complex, multitrait phenotypes: the contribution of rare, large effect variants in 2 Drosophila species

Funding

Current funding

  • 2019 - 2024
    The nature of standing genetic variation
    ARC Discovery Projects
    Open grant

Past funding

  • 2018 - 2021
    Understanding rapid adaptation to new environments
    ARC Discovery Projects
    Open grant
  • 2016 - 2019
    Understanding the fitness consequences of new mutations
    UQ Fellowships
    Open grant
  • 2015 - 2017
    The contribution of pleiotropic mutation to genetic variation and evolution
    ARC Discovery Projects
    Open grant
  • 2012 - 2016
    Understanding phenotypes: Contributions from studying mutations in a model organism
    ARC Future Fellowships
    Open grant
  • 2005 - 2007
    Multivariate Quantitative Genetics And The Lek Paradox
    ARC Discovery Projects
    Open grant

Supervision

Availability

Associate Professor Katrina McGuigan is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

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