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The nature of standing genetic variation (2019-2024)

Abstract

This project aims to expand our understanding of the genetic variation underlying phenotypic differences among individuals. The nature of genetic variation has broad consequences across biology, from the detection of causal genetic variants to the adaptation of natural populations. This project will take a novel experimental approach to test several long-standing assumptions about the effects of new mutations on individual traits and their joint pleiotropic effect on fitness. By expanding our understanding of how mutation, selection and drift interact, this project could provide significant improvements in our understanding of the genetic basis of phenotypes, and our ability to predict phenotypic evolution.

Experts

Associate Professor Katrina McGuigan

Associate Professor and Deputy Head of School
School of the Environment
Faculty of Science
Katrina McGuigan
Katrina McGuigan

Professor Mark Blows

Provost and Senior Vice-President
Office of the Vice-Chancellor
Mark Blows
Mark Blows