Overview
Background
Our lab aims to test fundamental hypotheses in genetics and evolutionary biology. Principally, we are interested the relationship between genotypic and phenotypic change during adaptive evolution. This line of inquiry requires an understanding of both the type of selection acting on traits as they evolve and ultimately the functional polymorphisms available for selection to act upon. We presently use both native and exotic species of Drosophila in our work but also undertake collaborative study in other organisms that represent examples of recurring ecological and evolutionary phenomena. We are equipped to use a broad range of techniques in our investigations including experimental evolution, field-based selection studies, quantitative genetics, molecular population genetics, genomics and advanced quantitative methods in statistics and computational biology. The broad range of techniques available to our group provides students with a unique opportunity to broaden their skill sets as they address fundamental questions.
Availability
- Professor Steve Chenoweth is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Griffith University
Research interests
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Sex-specific selection and its evolutionary consequences
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The evolution of sex-biased gene expression
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Quantitative genetics of the vectors of human infectious disease
Works
Search Professor Steve Chenoweth’s works on UQ eSpace
2024
Journal Article
The impacts of positive selection on genomic variation in <i>Drosophila serrata</i>: Insights from a deep learning approach
Wang, Yiguan, Allen, Scott L., Reddiex, Adam J. and Chenoweth, Stephen F. (2024). The impacts of positive selection on genomic variation in Drosophila serrata: Insights from a deep learning approach. Molecular Ecology. doi: 10.1111/mec.17499
2024
Other Outputs
Drosophila serrata genome scaffolding and annotation
Allen, Scott and Chenoweth, Steve (2024). Drosophila serrata genome scaffolding and annotation. The University of Queensland. (Dataset) doi: 10.48610/ce96855
2024
Journal Article
Misalignment of plastic and evolutionary responses of lifespan to novel carbohydrate diets
Narayan, Vikram P., Wasana, Nidarshani, Wilson, Alastair J. and Chenoweth, Stephen F. (2024). Misalignment of plastic and evolutionary responses of lifespan to novel carbohydrate diets. Royal Society Open Science, 11 (1) 231732, 231732. doi: 10.1098/rsos.231732
2023
Journal Article
Environmental dependence of mutational (co)variances of adaptive traits
Kannan, Ashvitha, Dugand, Robert J., Appleton, Nicholas C., Chenoweth, Stephen F., Sgrò, Carla M. and McGuigan, Katrina (2023). Environmental dependence of mutational (co)variances of adaptive traits. Evolution, 77 (11), 2341-2351. doi: 10.1093/evolut/qpad154
2023
Journal Article
Dengue and chikungunya virus loads in the mosquito Aedes aegypti are determined by distinct genetic architectures
Novelo, Mario, Dutra, Heverton LC, Metz, Hillery C., Jones, Matthew J., Sigle, Leah T., Frentiu, Francesca D., Allen, Scott L., Chenoweth, Stephen F. and McGraw, Elizabeth A. (2023). Dengue and chikungunya virus loads in the mosquito Aedes aegypti are determined by distinct genetic architectures. PLoS Pathogens, 19 (4) e1011307, e1011307. doi: 10.1371/journal.ppat.1011307
2022
Journal Article
Maintenance of quantitative genetic variance in complex, multitrait phenotypes: the contribution of rare, large effect variants in 2 Drosophila species
Hine, Emma, Runcie, Daniel E., Allen, Scott L., Wang, Yiguan, Chenoweth, Stephen F., Blows, Mark W. and McGuigan, Katrina (2022). Maintenance of quantitative genetic variance in complex, multitrait phenotypes: the contribution of rare, large effect variants in 2 Drosophila species. Genetics, 222 (2) iyac122, 1-17. doi: 10.1093/genetics/iyac122
2022
Journal Article
Natural variation at a single gene generates sexual antagonism across fitness components in Drosophila
Rusuwa, Bosco B., Chung, Henry, Allen, Scott L., Frentiu, Francesca D. and Chenoweth, Stephen F. (2022). Natural variation at a single gene generates sexual antagonism across fitness components in Drosophila. Current Biology, 32 (14), 3161-3169.e7. doi: 10.1016/j.cub.2022.05.038
2022
Journal Article
Genetic and social contributions to sex differences in lifespan in Drosophila serrata
Narayan, Vikram P., Wilson, Alastair J. and Chenoweth, Stephen F. (2022). Genetic and social contributions to sex differences in lifespan in Drosophila serrata. Journal of Evolutionary Biology, 35 (4), 657-663. doi: 10.1111/jeb.13992
2021
Other Outputs
R code and input files required to generate figures and tables for BSFG analysis of standing variance in two Drosophila datasets. This dataset is the current version and supercedes any earlier versions.
Hine, Emma, Runcie, Daniel E. , Allen, Scott L. , Wang, Yiguan , Chenoweth, Stephen F. , Blows, Mark W. and McGuigan, Katrina (2021). R code and input files required to generate figures and tables for BSFG analysis of standing variance in two Drosophila datasets. This dataset is the current version and supercedes any earlier versions.. The University of Queensland. (Dataset) doi: 10.48610/a3c5652
2021
Journal Article
Integrating genomics and multivariate evolutionary quantitative genetics: a case study of constraints on sexual selection in Drosophila serrata
Reddiex, Adam J. and Chenoweth, Stephen F. (2021). Integrating genomics and multivariate evolutionary quantitative genetics: a case study of constraints on sexual selection in Drosophila serrata. Proceedings of the Royal Society B: Biological Sciences, 288 (1960) 20211785, 20211785-197. doi: 10.1098/rspb.2021.1785
2021
Other Outputs
Enrichment analysis results for heritable common factors of Drosophila gene expression
Hine, Emma, Runcie, Daniel E., Allen, Scott L., Wang, Yiguan, Chenoweth, Stephen F., Blows, Mark W. and McGuigan, Katrina (2021). Enrichment analysis results for heritable common factors of Drosophila gene expression. The University of Queensland. (Dataset) doi: 10.48610/90441fc
2021
Journal Article
The impact of artificial selection for Wolbachia-mediated dengue virus blocking on phage WO
Dutra, Heverton L. C., Ford, Suzanne A., Allen, Scott L., Bordenstein, Sarah R., Chenoweth, Stephen F., Bordenstein, Seth R. and McGraw, Elizabeth A. (2021). The impact of artificial selection for Wolbachia-mediated dengue virus blocking on phage WO. PLoS Neglected Tropical Diseases, 15 (7) e0009637, e0009637. doi: 10.1371/journal.pntd.0009637
2021
Other Outputs
R code used to implement Bayesian sparse factor genetic analysis of Drosophila gene expression.
Hine, Emma, Runcie, Daniel E., Allen, Scott L., Wang, Yiguan, Chenoweth, Stephen F., Blows, Mark W. and McGuigan, Katrina (2021). R code used to implement Bayesian sparse factor genetic analysis of Drosophila gene expression.. The University of Queensland. (Dataset) doi: 10.48610/ec9b92c
2021
Other Outputs
Two Drosophila datasets used in the Bayesian sparse factor analysis of standing genetic variance in 3385 gene expression traits
Hine, Emma , Runcie, Daniel E., Allen, Scott L., Wang, Yiguan, Chenoweth, Stephen F. , Blows, Mark W. and McGuigan, Katrina (2021). Two Drosophila datasets used in the Bayesian sparse factor analysis of standing genetic variance in 3385 gene expression traits. The University of Queensland. (Dataset) doi: 10.48610/f3eede4
2020
Journal Article
Artificial selection finds new hypotheses for the mechanism of Wolbachia-mediated dengue blocking in mosquitoes
Ford, Suzanne A., Albert, Istvan, Allen, Scott L., Chenoweth, Stephen F., Jones, Matthew, Koh, Cassandra, Sebastian, Aswathy, Sigle, Leah T. and McGraw, Elizabeth A. (2020). Artificial selection finds new hypotheses for the mechanism of Wolbachia-mediated dengue blocking in mosquitoes. Frontiers in Microbiology, 11 1456, 1456. doi: 10.3389/fmicb.2020.01456
2019
Journal Article
Selection on Aedes aegypti alters Wolbachia-mediated dengue virus blocking and fitness
Ford, Suzanne A., Allen, Scott L., Ohm, Johanna R., Sigle, Leah T., Sebastian, Aswathy, Albert, Istvan, Chenoweth, Stephen F. and McGraw, Elizabeth A. (2019). Selection on Aedes aegypti alters Wolbachia-mediated dengue virus blocking and fitness. Nature Microbiology, 4 (11), 1832-1839. doi: 10.1038/s41564-019-0533-3
2019
Journal Article
The origin and maintenance of metabolic allometry in animals
White, Craig R., Marshall, Dustin J., Alton, Lesley A., Arnold, Pieter A., Beaman, Julian E., Bywater, Candice L., Condon, Catriona, Crispin, Taryn S., Janetzki, Aidan, Pirtle, Elia, Winwood-Smith, Hugh S., Angilletta, Michael J., Chenoweth, Stephen F., Franklin, Craig E., Halsey, Lewis G., Kearney, Michael R., Portugal, Steven J. and Ortiz-Barrientos, Daniel (2019). The origin and maintenance of metabolic allometry in animals. Nature Ecology and Evolution, 3 (4), 598-603. doi: 10.1038/s41559-019-0839-9
2019
Journal Article
Dominance reversals and the maintenance of genetic variation for fitness
Connallon, Tim and Chenoweth, Stephen F. (2019). Dominance reversals and the maintenance of genetic variation for fitness. Plos Biology, 17 (1) e3000118, e3000118. doi: 10.1371/journal.pbio.3000118
2019
Conference Publication
Using evolutionary approaches to dissect the genetic basis of Wolbachia-mediated blocking of dengue virus in Aedes aegypti
Ford, Suzanne, Allen, Scott, Sebastian, Aswathy, Albert, Istvan, Chenoweth, Stephen and McGraw, Elizabeth (2019). Using evolutionary approaches to dissect the genetic basis of Wolbachia-mediated blocking of dengue virus in Aedes aegypti. 68th Annual Meeting of the American Society for Tropical Medicine and Hygiene (ASTMH), National Harbor, MD, United States, 20 - 24 November 2019. Deerfield, IL, United States: American Society of Tropical Medicine and Hygiene. doi: 10.4269/ajtmh.abstract2019
2018
Journal Article
The transcriptional response of Aedes aegypti with variable extrinsic incubation periods for dengue virus
Koh, Cassandra, Allen, Scott L., Herbert, Rosemarie I., McGraw, Elizabeth A. and Chenoweth, Stephen F. (2018). The transcriptional response of Aedes aegypti with variable extrinsic incubation periods for dengue virus. Genome Biology and Evolution, 10 (12), 3141-3151. doi: 10.1093/gbe/evy230
Funding
Current funding
Supervision
Availability
- Professor Steve Chenoweth is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
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Doctor Philosophy
Context dependence of new mutations: the role of ancestral alleles and sex.
Associate Advisor
Other advisors: Dr Masato Yamamichi, Associate Professor Katrina McGuigan
Completed supervision
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2023
Doctor Philosophy
Evolutionary potential of Macronutrient Preferences of Drosophila serrata
Principal Advisor
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2023
Doctor Philosophy
The Relationships Between Dietary Macronutrients and Ageing
Principal Advisor
Other advisors: Associate Professor Katrina McGuigan
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2021
Doctor Philosophy
The impact of natural selection on genomic variation in natural and experimental populations of Drosophila serrata
Principal Advisor
Other advisors: Dr Scott Allen, Professor Daniel Ortiz-Barrientos
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2021
Master Philosophy
The impacts of mutation and selection on sex-biased gene expression in Drosophila serrata
Principal Advisor
Other advisors: Associate Professor Katrina McGuigan
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2019
Doctor Philosophy
Genomics of sexually selected traits in Drosophila serrata
Principal Advisor
Other advisors: Professor Daniel Ortiz-Barrientos
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2018
Doctor Philosophy
The evolution of sex-biased gene expression in Drosophila serrata
Principal Advisor
Other advisors: Professor Daniel Ortiz-Barrientos
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2015
Doctor Philosophy
The Genetic Architecture and Evolution of Continuous Reaction Norms: Dissecting the Thermal Performance Curve
Principal Advisor
Other advisors: Professor Robbie Wilson
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2013
Doctor Philosophy
Genetic Dissection of a Major Polymorphism Underlying Population Divergence in Sexually Selected Pheromones in Drosophila serrata
Principal Advisor
Other advisors: Professor Daniel Ortiz-Barrientos
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2023
Doctor Philosophy
The contribution of new mutations to genetic variation of quantitative traits
Associate Advisor
Other advisors: Professor Mark Blows, Associate Professor Katrina McGuigan
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2016
Doctor Philosophy
Stabilizing selection and the evolution of genetic variance in multivariate traits in Drosophila serrata
Associate Advisor
Other advisors: Associate Professor Katrina McGuigan, Professor Mark Blows
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2016
Doctor Philosophy
Genetics of phosphine resistance in the rice weevil Sitophilus oryzae (L.) (Coleoptera: Curculionidae)
Associate Advisor
Other advisors: Associate Professor Paul Ebert
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2015
Doctor Philosophy
Developing genomic resources for an emerging ecological model species Senecio lautus
Associate Advisor
Other advisors: Professor Daniel Ortiz-Barrientos
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2015
Doctor Philosophy
The genomic basis of parallel ecological speciation
Associate Advisor
Other advisors: Professor Daniel Ortiz-Barrientos
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2012
Doctor Philosophy
Phenotypic and genetic constraints on the reversible acclimation of thermal performance curves in the zebrafish, Danio rerio.
Associate Advisor
Other advisors: Professor Robbie Wilson
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2011
Doctor Philosophy
An investigation of the genetic components controlling reproduction, germline development and sex in Marsupenaeus japonicus (Bate).
Associate Advisor
Other advisors: Professor Bernard Degnan
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2008
Doctor Philosophy
Reinforcement and Sexual Selection: Interaction and Effect on Mate Recognition
Associate Advisor
Other advisors: Professor Mark Blows
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2008
Doctor Philosophy
Patterns of Genetic Regulation of Cuticular Hydrocarbons in Two Phylogenetically Distinct Drosophila Species: conserved mechanisms of ecological adaptation and sexual signalling
Associate Advisor
Other advisors: Professor Mark Blows
Media
Enquiries
Contact Professor Steve Chenoweth directly for media enquiries about:
- Drosophila
- Evolutionary Biology
- Genetic basis of behaviour
- Genetics - biology
- Population Genetics
- Sex-differences
- Statistical Genetics
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