
Overview
Background
Professor Anders Cervin has a longstanding interest in sino-nasal disorders, endoscopic sinus surgery as well as endoscopic anterior skull base surgery. His research interests includes mucociliary function in the upper airways, the role of Nitric Oxide in chronic sinusitis, the use of macrolide antibiotics as a immune modulator in chronic sinusitis and health economic perspectives on sino-nasal disease. Recent research addresses the role of probiotics in airway infection and inflammation. He has authored several book chapters and over 50 peer reviewed articles.
Availability
- Honorary Professor Anders Cervin is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Chronic sinusitis
Alternative treatment with probiotics
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Otitis Media
Alternative treatment with probiotics
Research impacts
Treatment of Chronic Sinusits and Middle Ear Infections (Otitis Media) with Probiotics
Chronic rhinosinusitis (CRS) affects 8-10% of the western population, mainly middle-aged adults in the prime of their working life, and causes a significant reduction in quality of life. Although unproven the mainstay of treatment have been antibiotics, unfortunately with limited long-term success. Another difficult to treat infection, is recurrent middle ear infection, especially prevalent in Indigenous children. Our research group have focused on identifying friendly bacteria in the upper airways of indigenous children as well as adults with chronic sinusitis. The approach is unique as we are targeting what is maintaining health rather than what causes disease. Thus we have identified a number of bacterial strains that have the capability of interfering with the pathogenic bacteria commonn in chronic sinusitis as well as in recurrent ear disease. We are now in the process of setting up clinical trials to test the effect of friendly bacteria on bacterial colonisation in the ears and sinuses. Should it be successful, it would be a paradigm shift in the way we treat upper airway infections and reduce the need for antibiotics and help to reduce antibiotic resistance in the community.
Works
Search Professor Anders Cervin’s works on UQ eSpace
2002
Journal Article
Acute exudative inflammation and nasally exhaled nitric oxide are two independent phenomena
Cervin, Anders, Greiff, Lennart, Lindberg, Sven and Andersson, Morgan (2002). Acute exudative inflammation and nasally exhaled nitric oxide are two independent phenomena. ORL, 64 (1), 26-31. doi: 10.1159/000049264
2002
Journal Article
The paranasal sinuses as reservoirs for nitric oxide
Andersson J.A., Cervin A., Lindberg S., Uddman R. and Cardell L.O. (2002). The paranasal sinuses as reservoirs for nitric oxide. Acta Oto-Laryngologica, 122 (8), 861-865. doi: 10.1080/003655402/000028053
2002
Journal Article
A decrease in maxillary sinus pressure, as seen in upper airway allergy or infection, results in an increase in upper airway nitric oxide levels
Andersson, Jens A., Cervin, Anders, Lindberg, Sven, Uddman, Rolf and Cardell, Lars Olaf (2002). A decrease in maxillary sinus pressure, as seen in upper airway allergy or infection, results in an increase in upper airway nitric oxide levels. Acta Oto-Laryngologica, 122 (5), 520-523. doi: 10.1080/00016480260092336
2001
Journal Article
The effect of intranasal budesonide spray on mucosal blood flow measured with Laser Doppler flowmetry
Cervin, A, Akerlund, A, Greiff, L and Andersson, M (2001). The effect of intranasal budesonide spray on mucosal blood flow measured with Laser Doppler flowmetry. Rhinology, 39 (1), 13-16.
2001
Journal Article
Evaluation of surgery for acromegaly: role of intraoperative growth hormone measurement?
Valdemarsson, S., Ljunggren, S., Cervin, A., Svensson, C., Isaksson, A., Nordstrom, C. -H. and Siesjo, P. (2001). Evaluation of surgery for acromegaly: role of intraoperative growth hormone measurement?. Scandinavian Journal of Clinical and Laboratory Investigation, 61 (6), 459-470. doi: 10.1080/00365510152567103
2001
Journal Article
The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis
Cervin A. (2001). The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis. Acta Oto-Laryngologica, 121 (1), 83-92. doi: 10.1080/000164801300006326
1999
Journal Article
Functional effects of neuropeptide Y receptors on blood flow and nitric oxide levels in the human nose
Cervin, A, Onnerfalt, J, Edvinsson, L and Grundemar, L (1999). Functional effects of neuropeptide Y receptors on blood flow and nitric oxide levels in the human nose. American Journal of Respiratory and Critical Care Medicine, 160 (5), 1724-1728.
1999
Journal Article
Effects on the ciliated epithelium of protein D-producing and - nonproducing nontypeable Haemophilus influenzae in nasopharyngeal tissue cultures
Janson H., Carlen B., Cervin A., Forsgren A., Magnusdottir A.B., Lindberg S. and Runer T. (1999). Effects on the ciliated epithelium of protein D-producing and - nonproducing nontypeable Haemophilus influenzae in nasopharyngeal tissue cultures. Journal of Infectious Diseases, 180 (3), 737-746. doi: 10.1086/314921
1998
Journal Article
Nitric oxide is a regulator of mucociliary activity in the upper respiratory tract
Runer, T, Cervin, A, Lindberg, S and Uddman, R (1998). Nitric oxide is a regulator of mucociliary activity in the upper respiratory tract. Otolaryngology-Head and Neck Surgery, 119 (3), 278-287. doi: 10.1016/S0194-5998(98)70063-4
1998
Journal Article
Changes in mucociliary activity may be used to investigate the airway-irritating potency of volatile anaesthetics
Cervin, A and Lindberg, S (1998). Changes in mucociliary activity may be used to investigate the airway-irritating potency of volatile anaesthetics. British Journal of Anaesthesia, 80 (4), 475-480.
1998
Journal Article
The effect of selective phosphodiesterase inhibitors on mucociliary activity in the upper and lower airways in vitro
Cervin A. and Lindgren S. (1998). The effect of selective phosphodiesterase inhibitors on mucociliary activity in the upper and lower airways in vitro. Auris Nasus Larynx, 25 (3), 269-276. doi: 10.1016/S0385-8146(98)00010-8
1998
Conference Publication
Regulation of mucociliary activity in the upper airways by nitric oxide - Clinical implications
Lindberg, S, Carlen, B, Cervin, A, Cramnert, C and Runer, T (1998). Regulation of mucociliary activity in the upper airways by nitric oxide - Clinical implications. International Congress on Cilia, Mucus, and Mucociliary Interactions, in Honor of Professor Alex Silberberg, Jerusalem Israel, Feb 23-27, 1997. MARCEL DEKKER.
1997
Journal Article
Low levels of nasal nitric oxide (NO) correlate to impaired mucociliary function in the upper airways
Lindberg, S, Cervin, A and Runer, T (1997). Low levels of nasal nitric oxide (NO) correlate to impaired mucociliary function in the upper airways. Acta Oto-Laryngologica, 117 (5), 728-734. doi: 10.3109/00016489709113468
1997
Journal Article
Nitric oxide (NO) production in the upper airways is decreased in chronic sinusitis
Lindberg, S, Cervin, A and Runer, T (1997). Nitric oxide (NO) production in the upper airways is decreased in chronic sinusitis. Acta Oto-Laryngologica, 117 (1), 113-117. doi: 10.3109/00016489709118001
1996
Journal Article
Recordings of mucociliary activity in vivo: Benefit of fast Fourier transformation of the photoelectric signal
Lindberg, S, Cervin, A, Runer, T and Thomasson, L (1996). Recordings of mucociliary activity in vivo: Benefit of fast Fourier transformation of the photoelectric signal. Annals of Otology Rhinology and Laryngology, 105 (9), 734-745.
1996
Journal Article
Sinonasal T-cell lymphoma and Wegener's granulomatosis: Aspects in early differential diagnosis
Cervin, A, Dictor, M and Kalm, O (1996). Sinonasal T-cell lymphoma and Wegener's granulomatosis: Aspects in early differential diagnosis. American Journal of Rhinology, 10 (4), 239-246. doi: 10.2500/105065896782103126
1996
Journal Article
Sinonasal T-cell lymphoma in the differential diagnosis of lethal midline granuloma using in situ hybridization for Epstein-Barr virus RNA
Dictor, M, Cervin, A, Kalm, O and Rambech, E (1996). Sinonasal T-cell lymphoma in the differential diagnosis of lethal midline granuloma using in situ hybridization for Epstein-Barr virus RNA. Modern Pathology, 9 (1), 7-14.
1995
Journal Article
Effects of Halothane On Mucociliary Activity In-Vivo
Cervin, A, Lindberg, S and Mercke, U (1995). Effects of Halothane On Mucociliary Activity In-Vivo. Otolaryngology-Head and Neck Surgery, 112 (6), 714-722.
1995
Journal Article
Cyclic Adenosine-Monophosphate Stimulation of Mucociliary Activity in the Upper Airways In-Vivo
Cervin, A, Lindberg, S, Dolata, J and Mercke, U (1995). Cyclic Adenosine-Monophosphate Stimulation of Mucociliary Activity in the Upper Airways In-Vivo. Annals of Otology Rhinology and Laryngology, 104 (5), 388-393.
1992
Journal Article
Neuropeptide-Y in the Rabbit Maxillary Sinus Modulates Cholinergic Acceleration of Mucociliary Activity
Cervin, A, Lindberg, S, Mercke, U and Uddman, R (1992). Neuropeptide-Y in the Rabbit Maxillary Sinus Modulates Cholinergic Acceleration of Mucociliary Activity. Acta Oto-Laryngologica, 112 (5), 872-881. doi: 10.3109/00016489209137486
Supervision
Availability
- Honorary Professor Anders Cervin is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
Testing a sinonasal microbiome transplant as a therapy for Chronic Rhinosinusitis by randomised controlled trial
Principal Advisor
Other advisors: Dr Diane Maresco-Pennisi
Completed supervision
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2021
Doctor Philosophy
The microbiome of otitis media and development of a probiotic to prevent otitis media in Indigenous Australian children
Principal Advisor
Other advisors: Dr Seweryn Bialasiewicz
Media
Enquiries
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- sinusitis
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