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Honorary Professor Anders Cervin
Honorary Professor

Anders Cervin

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Overview

Background

Professor Anders Cervin has a longstanding interest in sino-nasal disorders, endoscopic sinus surgery as well as endoscopic anterior skull base surgery. His research interests includes mucociliary function in the upper airways, the role of Nitric Oxide in chronic sinusitis, the use of macrolide antibiotics as a immune modulator in chronic sinusitis and health economic perspectives on sino-nasal disease. Recent research addresses the role of probiotics in airway infection and inflammation. He has authored several book chapters and over 50 peer reviewed articles.

Availability

Honorary Professor Anders Cervin is:
Available for supervision
Media expert

Research interests

  • Chronic sinusitis

    Alternative treatment with probiotics

  • Otitis Media

    Alternative treatment with probiotics

Research impacts

Treatment of Chronic Sinusits and Middle Ear Infections (Otitis Media) with Probiotics

Chronic rhinosinusitis (CRS) affects 8-10% of the western population, mainly middle-aged adults in the prime of their working life, and causes a significant reduction in quality of life. Although unproven the mainstay of treatment have been antibiotics, unfortunately with limited long-term success. Another difficult to treat infection, is recurrent middle ear infection, especially prevalent in Indigenous children. Our research group have focused on identifying friendly bacteria in the upper airways of indigenous children as well as adults with chronic sinusitis. The approach is unique as we are targeting what is maintaining health rather than what causes disease. Thus we have identified a number of bacterial strains that have the capability of interfering with the pathogenic bacteria commonn in chronic sinusitis as well as in recurrent ear disease. We are now in the process of setting up clinical trials to test the effect of friendly bacteria on bacterial colonisation in the ears and sinuses. Should it be successful, it would be a paradigm shift in the way we treat upper airway infections and reduce the need for antibiotics and help to reduce antibiotic resistance in the community.

Works

Search Professor Anders Cervin’s works on UQ eSpace

85 works between 1988 and 2024

61 - 80 of 85 works

2002

Journal Article

The paranasal sinuses as reservoirs for nitric oxide

Andersson J.A., Cervin A., Lindberg S., Uddman R. and Cardell L.O. (2002). The paranasal sinuses as reservoirs for nitric oxide. Acta Oto-Laryngologica, 122 (8), 861-865. doi: 10.1080/003655402/000028053

The paranasal sinuses as reservoirs for nitric oxide

2002

Journal Article

A decrease in maxillary sinus pressure, as seen in upper airway allergy or infection, results in an increase in upper airway nitric oxide levels

Andersson, Jens A., Cervin, Anders, Lindberg, Sven, Uddman, Rolf and Cardell, Lars Olaf (2002). A decrease in maxillary sinus pressure, as seen in upper airway allergy or infection, results in an increase in upper airway nitric oxide levels. Acta Oto-Laryngologica, 122 (5), 520-523. doi: 10.1080/00016480260092336

A decrease in maxillary sinus pressure, as seen in upper airway allergy or infection, results in an increase in upper airway nitric oxide levels

2002

Journal Article

Acute exudative inflammation and nasally exhaled nitric oxide are two independent phenomena

Cervin, Anders, Greiff, Lennart, Lindberg, Sven and Andersson, Morgan (2002). Acute exudative inflammation and nasally exhaled nitric oxide are two independent phenomena. ORL, 64 (1), 26-31. doi: 10.1159/000049264

Acute exudative inflammation and nasally exhaled nitric oxide are two independent phenomena

2001

Journal Article

The effect of intranasal budesonide spray on mucosal blood flow measured with Laser Doppler flowmetry

Cervin, A, Akerlund, A, Greiff, L and Andersson, M (2001). The effect of intranasal budesonide spray on mucosal blood flow measured with Laser Doppler flowmetry. Rhinology, 39 (1), 13-16.

The effect of intranasal budesonide spray on mucosal blood flow measured with Laser Doppler flowmetry

2001

Journal Article

Evaluation of surgery for acromegaly: role of intraoperative growth hormone measurement?

Valdemarsson, S., Ljunggren, S., Cervin, A., Svensson, C., Isaksson, A., Nordstrom, C. -H. and Siesjo, P. (2001). Evaluation of surgery for acromegaly: role of intraoperative growth hormone measurement?. Scandinavian Journal of Clinical and Laboratory Investigation, 61 (6), 459-470. doi: 10.1080/00365510152567103

Evaluation of surgery for acromegaly: role of intraoperative growth hormone measurement?

2001

Journal Article

The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis

Cervin A. (2001). The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis. Acta Oto-Laryngologica, 121 (1), 83-92. doi: 10.1080/000164801300006326

The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis

1999

Journal Article

Functional effects of neuropeptide Y receptors on blood flow and nitric oxide levels in the human nose

Cervin, A, Onnerfalt, J, Edvinsson, L and Grundemar, L (1999). Functional effects of neuropeptide Y receptors on blood flow and nitric oxide levels in the human nose. American Journal of Respiratory and Critical Care Medicine, 160 (5), 1724-1728.

Functional effects of neuropeptide Y receptors on blood flow and nitric oxide levels in the human nose

1999

Journal Article

Effects on the ciliated epithelium of protein D-producing and - nonproducing nontypeable Haemophilus influenzae in nasopharyngeal tissue cultures

Janson H., Carlen B., Cervin A., Forsgren A., Magnusdottir A.B., Lindberg S. and Runer T. (1999). Effects on the ciliated epithelium of protein D-producing and - nonproducing nontypeable Haemophilus influenzae in nasopharyngeal tissue cultures. Journal of Infectious Diseases, 180 (3), 737-746. doi: 10.1086/314921

Effects on the ciliated epithelium of protein D-producing and - nonproducing nontypeable Haemophilus influenzae in nasopharyngeal tissue cultures

1998

Journal Article

Nitric oxide is a regulator of mucociliary activity in the upper respiratory tract

Runer, T, Cervin, A, Lindberg, S and Uddman, R (1998). Nitric oxide is a regulator of mucociliary activity in the upper respiratory tract. Otolaryngology-Head and Neck Surgery, 119 (3), 278-287. doi: 10.1016/S0194-5998(98)70063-4

Nitric oxide is a regulator of mucociliary activity in the upper respiratory tract

1998

Journal Article

Changes in mucociliary activity may be used to investigate the airway-irritating potency of volatile anaesthetics

Cervin, A and Lindberg, S (1998). Changes in mucociliary activity may be used to investigate the airway-irritating potency of volatile anaesthetics. British Journal of Anaesthesia, 80 (4), 475-480.

Changes in mucociliary activity may be used to investigate the airway-irritating potency of volatile anaesthetics

1998

Conference Publication

Regulation of mucociliary activity in the upper airways by nitric oxide - Clinical implications

Lindberg, S, Carlen, B, Cervin, A, Cramnert, C and Runer, T (1998). Regulation of mucociliary activity in the upper airways by nitric oxide - Clinical implications. International Congress on Cilia, Mucus, and Mucociliary Interactions, in Honor of Professor Alex Silberberg, Jerusalem Israel, Feb 23-27, 1997. MARCEL DEKKER.

Regulation of mucociliary activity in the upper airways by nitric oxide - Clinical implications

1998

Journal Article

The effect of selective phosphodiesterase inhibitors on mucociliary activity in the upper and lower airways in vitro

Cervin A. and Lindgren S. (1998). The effect of selective phosphodiesterase inhibitors on mucociliary activity in the upper and lower airways in vitro. Auris Nasus Larynx, 25 (3), 269-276. doi: 10.1016/S0385-8146(98)00010-8

The effect of selective phosphodiesterase inhibitors on mucociliary activity in the upper and lower airways in vitro

1997

Journal Article

Low levels of nasal nitric oxide (NO) correlate to impaired mucociliary function in the upper airways

Lindberg, S, Cervin, A and Runer, T (1997). Low levels of nasal nitric oxide (NO) correlate to impaired mucociliary function in the upper airways. Acta Oto-Laryngologica, 117 (5), 728-734. doi: 10.3109/00016489709113468

Low levels of nasal nitric oxide (NO) correlate to impaired mucociliary function in the upper airways

1997

Journal Article

Nitric oxide (NO) production in the upper airways is decreased in chronic sinusitis

Lindberg, S, Cervin, A and Runer, T (1997). Nitric oxide (NO) production in the upper airways is decreased in chronic sinusitis. Acta Oto-Laryngologica, 117 (1), 113-117. doi: 10.3109/00016489709118001

Nitric oxide (NO) production in the upper airways is decreased in chronic sinusitis

1996

Journal Article

Recordings of mucociliary activity in vivo: Benefit of fast Fourier transformation of the photoelectric signal

Lindberg, S, Cervin, A, Runer, T and Thomasson, L (1996). Recordings of mucociliary activity in vivo: Benefit of fast Fourier transformation of the photoelectric signal. Annals of Otology Rhinology and Laryngology, 105 (9), 734-745.

Recordings of mucociliary activity in vivo: Benefit of fast Fourier transformation of the photoelectric signal

1996

Journal Article

Sinonasal T-cell lymphoma and Wegener's granulomatosis: Aspects in early differential diagnosis

Cervin, A, Dictor, M and Kalm, O (1996). Sinonasal T-cell lymphoma and Wegener's granulomatosis: Aspects in early differential diagnosis. American Journal of Rhinology, 10 (4), 239-246. doi: 10.2500/105065896782103126

Sinonasal T-cell lymphoma and Wegener's granulomatosis: Aspects in early differential diagnosis

1996

Journal Article

Sinonasal T-cell lymphoma in the differential diagnosis of lethal midline granuloma using in situ hybridization for Epstein-Barr virus RNA

Dictor, M, Cervin, A, Kalm, O and Rambech, E (1996). Sinonasal T-cell lymphoma in the differential diagnosis of lethal midline granuloma using in situ hybridization for Epstein-Barr virus RNA. Modern Pathology, 9 (1), 7-14.

Sinonasal T-cell lymphoma in the differential diagnosis of lethal midline granuloma using in situ hybridization for Epstein-Barr virus RNA

1995

Journal Article

Effects of Halothane On Mucociliary Activity In-Vivo

Cervin, A, Lindberg, S and Mercke, U (1995). Effects of Halothane On Mucociliary Activity In-Vivo. Otolaryngology-Head and Neck Surgery, 112 (6), 714-722.

Effects of Halothane On Mucociliary Activity In-Vivo

1995

Journal Article

Cyclic Adenosine-Monophosphate Stimulation of Mucociliary Activity in the Upper Airways In-Vivo

Cervin, A, Lindberg, S, Dolata, J and Mercke, U (1995). Cyclic Adenosine-Monophosphate Stimulation of Mucociliary Activity in the Upper Airways In-Vivo. Annals of Otology Rhinology and Laryngology, 104 (5), 388-393.

Cyclic Adenosine-Monophosphate Stimulation of Mucociliary Activity in the Upper Airways In-Vivo

1992

Journal Article

Neuropeptide-Y in the Rabbit Maxillary Sinus Modulates Cholinergic Acceleration of Mucociliary Activity

Cervin, A, Lindberg, S, Mercke, U and Uddman, R (1992). Neuropeptide-Y in the Rabbit Maxillary Sinus Modulates Cholinergic Acceleration of Mucociliary Activity. Acta Oto-Laryngologica, 112 (5), 872-881. doi: 10.3109/00016489209137486

Neuropeptide-Y in the Rabbit Maxillary Sinus Modulates Cholinergic Acceleration of Mucociliary Activity

Funding

Current funding

  • 2021 - 2025
    Testing a sinonasal microbiome transplant as a therapy for Chronic Rhinosinusitis by randomised controlled trial
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant
  • 2020 - 2024
    Development of Phage Therapy to Combat Chronic Otitis Media in Indigenous Children
    NHMRC IDEAS Grants
    Open grant
  • 2017 - 2027
    Garnett Passe and Rodney Williams Memorial Foundation Chair in Otorhinolaryngology, Head and Neck Surgery
    Garnett Passe/Rodney Williams Memorial Foundation
    Open grant

Past funding

  • 2015 - 2019
    Microbiota of the human sinuses: Its role in health and disease
    Garnett Passe/Rodney Williams Memorial Foundation
    Open grant
  • 2015
    The role of the bacterial, fungal and viral sinus microbiome in chronic rhinosinusitis patients
    Royal Brisbane and Women's Hospital
    Open grant

Supervision

Availability

Honorary Professor Anders Cervin is:
Available for supervision

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Available projects

  • Probiotic treatment of Chronic Rhinosinusits

    The overall aim of the project is to improve quality of life in patients suffering from Chronic RhinoSinusitis (CRS). Specifically by manipulating mucosal immunology and reducing the load of microbial pathogens in CRS by topical administration of probiotic bacterial strains. You will work in a stimulating environment in close relationship with patients, ENT surgeons, microbiologists and other researchers. The project have international collaborators in the Netherlands and Sweden. The project is truly translational you will acquire skills in clinical trials (GCP), as well as gaining laboratory experience in microbiology and cytokine analysis.

Supervision history

Current supervision

  • Master Philosophy

    Testing a sinonasal microbiome transplant as a therapy for Chronic Rhinosinusitis by randomised controlled trial

    Principal Advisor

    Other advisors: Dr Diane Maresco-Pennisi

Completed supervision

Media

Enquiries

Contact Honorary Professor Anders Cervin directly for media enquiries about:

  • sinusitis

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