
Overview
Background
Professor Anders Cervin has a longstanding interest in sino-nasal disorders, endoscopic sinus surgery as well as endoscopic anterior skull base surgery. His research interests includes mucociliary function in the upper airways, the role of Nitric Oxide in chronic sinusitis, the use of macrolide antibiotics as a immune modulator in chronic sinusitis and health economic perspectives on sino-nasal disease. Recent research addresses the role of probiotics in airway infection and inflammation. He has authored several book chapters and over 50 peer reviewed articles.
Availability
- Honorary Professor Anders Cervin is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Chronic sinusitis
Alternative treatment with probiotics
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Otitis Media
Alternative treatment with probiotics
Research impacts
Treatment of Chronic Sinusits and Middle Ear Infections (Otitis Media) with Probiotics
Chronic rhinosinusitis (CRS) affects 8-10% of the western population, mainly middle-aged adults in the prime of their working life, and causes a significant reduction in quality of life. Although unproven the mainstay of treatment have been antibiotics, unfortunately with limited long-term success. Another difficult to treat infection, is recurrent middle ear infection, especially prevalent in Indigenous children. Our research group have focused on identifying friendly bacteria in the upper airways of indigenous children as well as adults with chronic sinusitis. The approach is unique as we are targeting what is maintaining health rather than what causes disease. Thus we have identified a number of bacterial strains that have the capability of interfering with the pathogenic bacteria commonn in chronic sinusitis as well as in recurrent ear disease. We are now in the process of setting up clinical trials to test the effect of friendly bacteria on bacterial colonisation in the ears and sinuses. Should it be successful, it would be a paradigm shift in the way we treat upper airway infections and reduce the need for antibiotics and help to reduce antibiotic resistance in the community.
Works
Search Professor Anders Cervin’s works on UQ eSpace
2015
Journal Article
Cellular and molecular mechanisms of chronic rhinosinusitis and potential therapeutic strategies: review on cytokines, nuclear factor kappa B and transforming growth factor beta
Phan, N.T., Cabot, P.J., Wallwork, B.D., Cervin, A.U. and Panizza, B.J. (2015). Cellular and molecular mechanisms of chronic rhinosinusitis and potential therapeutic strategies: review on cytokines, nuclear factor kappa B and transforming growth factor beta. Journal of Laryngology and Otology, 129 (S3), S2-S7. doi: 10.1017/S0022215115001322
2015
Journal Article
Reducing the number of rigid bronchoscopies performed in suspected foreign body aspiration cases via the use of chest computed tomography: is it safe? A literature review
Tuckett, P. and Cervin, A. (2015). Reducing the number of rigid bronchoscopies performed in suspected foreign body aspiration cases via the use of chest computed tomography: is it safe? A literature review. Journal of Laryngology and Otology, 129 (S1), S1-S7. doi: 10.1017/S0022215114002862
2014
Journal Article
Treatment with a topical glucocorticoid, budesonide, reduced the variability of rhinomanometric nasal airway resistance
Thulesius, Helle L., Cervin, Anders and Jessen, Max (2014). Treatment with a topical glucocorticoid, budesonide, reduced the variability of rhinomanometric nasal airway resistance. Rhinology, 52 (1), 19-24. doi: 10.4193/Rhino12.180
2014
Journal Article
Efficacy and safety of long-term antibiotics (macrolides) for the treatment of chronic rhinosinusitis
Cervin, Anders and Wallwork, Ben (2014). Efficacy and safety of long-term antibiotics (macrolides) for the treatment of chronic rhinosinusitis. Current Allergy and Asthma Reports, 14 (3) 416, 416.1-416.7. doi: 10.1007/s11882-013-0416-2
2012
Journal Article
Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis
Greiff, Lennart, Cervin, Anders, Ahlstrom-Emanuelsson, Cecilia, Almqvist, Gun, Andersson, Morgan, Dolata, Jan, Eriksson, Leif, Hogestatt, Edward, Kallen, Anders, Norlen, Per, Sjolin, Inga-Lisa and Widegren, Henrik (2012). Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis. Respiratory Research, 13 53, 53.1-53.10. doi: 10.1186/1465-9921-13-53
2012
Journal Article
Internationella riktlinjer för allergisk rinit har uppdaterats: Nu presenteras behandlingsalgoritm anpassad till svenska förhållanden
Cardell, Lars Olaf, Wickman, Magnus, Hellgren, Johan, Cervin, Anders, Stjärne, Pär, Holmström, Mats, Dahlén, Barbro, Bjermer, Leif and Dahlén, Sven-Erik (2012). Internationella riktlinjer för allergisk rinit har uppdaterats: Nu presenteras behandlingsalgoritm anpassad till svenska förhållanden. Lakartidningen, 109 (12), 622-624.
2012
Journal Article
European position paper on rhinosinusitis and nasal polyps 2012
Fokkens, Wytske J., Lund, Valerie J., Mullol, Joachim, Bachert, Claus, Alobid, Isam, Baroody, Fuad, Cohen, Noam, Cervin, Anders, Douglas, Richard, Gevaert, Philippe, Georgalas, Christos, Goossens, Herman, Harvey, Richard, Hellings, Peter, Hopkins, Claire, Jones, Nick, Joos, Guy, Kalogjera, Livije, Kern, Bob, Kowalski, Marek, Price, David, Riechelmann, Herbert, Schlosser, Rodney, Senior, Brent, Thomas, Mike, Toskala, Elina, Voegels, Richard, Wang, De Yun and Wormald, Peter John (2012). European position paper on rhinosinusitis and nasal polyps 2012. Rhinology, 50 (Supp. 3), 4-305.
2012
Journal Article
EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists
Fokkens, Wytske J., Lund, Valerie J., Mullol, Joachim, Bachert, Claus, Alobid, Isam, Baroody, Fuad, Cohen, Noam, Cervin, Anders, Douglas, Richard, Gevaert, Philippe, Georgalas, Christos, Goossens, Herman, Harvey, Richard, Hellings, Peter, Hopkins, Claire, Jones, Nick, Joos, Guy, Kalogjera, Livije, Kern, Bob, Kowalski, Marek, Price, David, Riechelmann, Herbert, Schlosser, Rodney, Senior, Brent, Thomas, Mike, Toskala, Elina, Voegels, Richard, Wang, De Yun and Wormald, Peter John (2012). EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology, 50 (1), 1-12. doi: 10.4193/rhino50e2
2012
Journal Article
The importance of side difference in nasal obstruction and rhinomanometry: a retrospective correlation of symptoms and rhinomanometry in 1000 patients
Thulesius, H. L., Cervin, A. and Jessen, M. (2012). The importance of side difference in nasal obstruction and rhinomanometry: a retrospective correlation of symptoms and rhinomanometry in 1000 patients. Clinical Otolaryngology, 37 (1), 17-22. doi: 10.1111/j.1749-4486.2011.02420.x
2011
Journal Article
NOD-like receptors in the human upper airways: a potential role in nasal polyposis
Mansson, A., Bogefors, J., Cervin, A., Uddman, R. and Cardell, L. O. (2011). NOD-like receptors in the human upper airways: a potential role in nasal polyposis. Allergy: European Journal of Allergy and Clinical Immunology, 66 (5), 621-628. doi: 10.1111/j.1398-9995.2010.02527.x
2011
Journal Article
Can we always trust rhinomanometry?
Thulesius, H. L., Cervin, A. and Jessen, M. (2011). Can we always trust rhinomanometry?. Rhinology, 49 (1), 46-52. doi: 10.4193/Rhino10.027
2010
Journal Article
Is it time to abandon chronic rhinosinusitis? (Or at least to introduce the term unexplained chronic rhinosinusitis)
Cervin, Anders (2010). Is it time to abandon chronic rhinosinusitis? (Or at least to introduce the term unexplained chronic rhinosinusitis). Rhinology, 48 (1), 123-124.
2010
Journal Article
Allergic rhinitis and the common cold - high cost to society
Hellgren, J., Cervin, A., Nordling, S., Bergman, A. and Cardell, L. O. (2010). Allergic rhinitis and the common cold - high cost to society. Allergy: European Journal of Allergy and Clinical Immunology, 65 (6), 776-783. doi: 10.1111/j.1398-9995.2009.02269.x
2009
Journal Article
Effects of long-term clarithromycin treatment on lavage-fluid markers of inflammation in chronic rhinosinusitis
Cervin, Anders, Wallwork, Ben, Mackay-Sim, Alan, Coman, William B. and Greiff, Lennart (2009). Effects of long-term clarithromycin treatment on lavage-fluid markers of inflammation in chronic rhinosinusitis. Clinical Physiology and Functional Imaging, 29 (2), 136-142. doi: 10.1111/j.1475-097X.2008.00848.x
2009
Journal Article
Genes regulating molecular and cellular functions in noninfectious nonallergic rhinitis
Cardell, L. O., Andersson, M., Cervin, A., Davidsson, A., Hellgren, J., Holmstrom, M., Lundblad, L., Stierna, P., Stjarne, P., Adner, M. and SRFA study group (2009). Genes regulating molecular and cellular functions in noninfectious nonallergic rhinitis. Allergy: European Journal of Allergy and Clinical Immunology, 64 (9), 1301-1308. doi: 10.1111/j.1398-9995.2009.02009.x
2007
Journal Article
Macrolide therapy of chronic rhinosinusitis
Cervin, Anders and Wallwork, Ben (2007). Macrolide therapy of chronic rhinosinusitis. Rhinology, 45 (4), 259-267.
2005
Journal Article
Anti-inflammatory effects of macrolide antibiotics in the treatment of chronic rhinosinusitis
Cervin A. and Wallwork B. (2005). Anti-inflammatory effects of macrolide antibiotics in the treatment of chronic rhinosinusitis. Otolaryngologic Clinics of North America, 38 (6), 1339-1350. doi: 10.1016/j.otc.2005.08.002
2004
Journal Article
Effect of clarithromycin on nuclear factor-kappa B and transforming growth factor-beta in chronic rhinosinusitis
Wallwork, Ben, Coman, William, Mackay-Sim, Alan and Cervin, Anders (2004). Effect of clarithromycin on nuclear factor-kappa B and transforming growth factor-beta in chronic rhinosinusitis. The Laryngoscope, 114 (2), 286-290. doi: 10.1097/00005537-200402000-00019
2003
Journal Article
Nasal septal perforations during treatment with topical nasal glucocorticosteroids are generally not associated with contact allergy to steroids
Cervin A., Hansson C., Greiff L. and Andersson M. (2003). Nasal septal perforations during treatment with topical nasal glucocorticosteroids are generally not associated with contact allergy to steroids. ORL, 65 (2), 103-105. doi: 10.1159/000070774
2002
Journal Article
One-year low-dose erythromycin treatment of persistent chronic sinusitis after sinus surgery: clinical outcome and effects on mucociliary parameters and nasal nitric oxide
Cervin, Anders, Kalm, Olof, Sandkull, Per and Lindberg, Sven (2002). One-year low-dose erythromycin treatment of persistent chronic sinusitis after sinus surgery: clinical outcome and effects on mucociliary parameters and nasal nitric oxide. Otolaryngology - Head and Neck Surgery, 126 (5), 481-489. doi: 10.1067/mhn.2002.124849
Supervision
Availability
- Honorary Professor Anders Cervin is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
Testing a sinonasal microbiome transplant as a therapy for Chronic Rhinosinusitis by randomised controlled trial
Principal Advisor
Other advisors: Dr Diane Maresco-Pennisi
Completed supervision
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2021
Doctor Philosophy
The microbiome of otitis media and development of a probiotic to prevent otitis media in Indigenous Australian children
Principal Advisor
Other advisors: Dr Seweryn Bialasiewicz
Media
Enquiries
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- sinusitis
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