
Overview
Background
Professor Anders Cervin has a longstanding interest in sino-nasal disorders, endoscopic sinus surgery as well as endoscopic anterior skull base surgery. His research interests includes mucociliary function in the upper airways, the role of Nitric Oxide in chronic sinusitis, the use of macrolide antibiotics as a immune modulator in chronic sinusitis and health economic perspectives on sino-nasal disease. Recent research addresses the role of probiotics in airway infection and inflammation. He has authored several book chapters and over 50 peer reviewed articles.
Availability
- Honorary Professor Anders Cervin is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Chronic sinusitis
Alternative treatment with probiotics
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Otitis Media
Alternative treatment with probiotics
Research impacts
Treatment of Chronic Sinusits and Middle Ear Infections (Otitis Media) with Probiotics
Chronic rhinosinusitis (CRS) affects 8-10% of the western population, mainly middle-aged adults in the prime of their working life, and causes a significant reduction in quality of life. Although unproven the mainstay of treatment have been antibiotics, unfortunately with limited long-term success. Another difficult to treat infection, is recurrent middle ear infection, especially prevalent in Indigenous children. Our research group have focused on identifying friendly bacteria in the upper airways of indigenous children as well as adults with chronic sinusitis. The approach is unique as we are targeting what is maintaining health rather than what causes disease. Thus we have identified a number of bacterial strains that have the capability of interfering with the pathogenic bacteria commonn in chronic sinusitis as well as in recurrent ear disease. We are now in the process of setting up clinical trials to test the effect of friendly bacteria on bacterial colonisation in the ears and sinuses. Should it be successful, it would be a paradigm shift in the way we treat upper airway infections and reduce the need for antibiotics and help to reduce antibiotic resistance in the community.
Works
Search Professor Anders Cervin’s works on UQ eSpace
2019
Journal Article
Phase 1 clinical study to assess the safety of a novel drug delivery system providing long-term topical steroid therapy for chronic rhinosinusitis
Douglas, Richard G., Psaltis, Alkis J., Rimmer, Joanne, Kuruvilla, Tom, Cervin, Anders and Kuang, Yina (2019). Phase 1 clinical study to assess the safety of a novel drug delivery system providing long-term topical steroid therapy for chronic rhinosinusitis. International Forum of Allergy and Rhinology, 9 (4), 378-387. doi: 10.1002/alr.22288
2019
Journal Article
EPOS2020: development strategy and goals for the latest European Position Paper on Rhinosinusitis
Fokkens, Wytske, Desrosiers, Martin, Harvey, Richard, Hopkins, Claire, Mullol, Joaquim, Philpott, Carl, Alobid, Isam, Anselmo-Lima, Wilma Terezinha, Bachert, Claus, Baroody, Fuad, Bernal-Sprekelsen, Manuel, von Buchwald, Christian, Cervin, Anders, Cohen, Noam, Constantinidis, Jannis, De Gabory, Ludovic, Douglas, Richard, Gevaert, Philippe, Hafner, Anita, Hellings, Peter, Joos, Guy, Kalogjera, Livije, Kern, Rob, Knill, Andrew, Kocks, Janwillem, Landis, Basile Nicolas, Limpens, Jacqueline, Lebeer, Sarah, Lourenco, Olga ... Lund, Valerie (2019). EPOS2020: development strategy and goals for the latest European Position Paper on Rhinosinusitis. Rhinology, 57 (3), 162-168. doi: 10.4193/Rhin17.253
2019
Journal Article
Probiotics in the treatment of otitis media. The past, the present and the future
Coleman, Andrea and Cervin, Anders (2019). Probiotics in the treatment of otitis media. The past, the present and the future. International Journal of Pediatric Otorhinolaryngology, 116, 135-140. doi: 10.1016/j.ijporl.2018.10.023
2018
Journal Article
The unsolved problem of otitis media in indigenous populations: a systematic review of upper respiratory and middle ear microbiology in indigenous children with otitis media
Coleman, Andrea, Wood, Amanda, Bialasiewicz, Seweryn, Ware, Robert S., Marsh, Robyn L. and Cervin, Anders (2018). The unsolved problem of otitis media in indigenous populations: a systematic review of upper respiratory and middle ear microbiology in indigenous children with otitis media. Microbiome, 6 (1) 199, 199. doi: 10.1186/s40168-018-0577-2
2018
Journal Article
Disease burden and productivity cost of chronic rhinosinusitis patients referred to a tertiary centre in Australia
Liu, Timothy, Cooper, Thomas, Earnshaw, James and Cervin, Anders (2018). Disease burden and productivity cost of chronic rhinosinusitis patients referred to a tertiary centre in Australia. Australian Journal of Otolaryngology, 1, 5-5. doi: 10.21037/ajo.2018.01.03
2018
Journal Article
Long-term patient-related outcome measures of septoplasty: a systematic review
Tsang, Chi Lap Nicholas, Nguyen, Theresa , Sivesind, Torunn and Cervin, Anders (2018). Long-term patient-related outcome measures of septoplasty: a systematic review. European Archives of Oto-rhino-laryngology, 275 (5), 1-10. doi: 10.1007/s00405-018-4874-y
2018
Journal Article
The potential for topical probiotic treatment of chronic rhinosinusitis, a personal perspective
Cervin, Anders U. (2018). The potential for topical probiotic treatment of chronic rhinosinusitis, a personal perspective. Frontiers in Cellular and Infection Microbiology, 7 (JAN) 530, 530. doi: 10.3389/fcimb.2017.00530
2018
Journal Article
CHronic rhinosinusitis outcome MEasures (CHROME) – developing a core outcome set for trials of interventions in chronic rhinosinusitis
Hopkins, Claire, Hettige, Roland, Soni-Jaiswal, Archana, Lakhani, Raj, Carrie, Sean, Cervin, Anders, Douglas, Richard, Fokkens, Wytske, Harvey, Richard, Hellings, Peter, Leunig, Andreas, Lund, Valerie, Philpott, Carl, Smith, Tim, Wang, De-Yun and Rudmik, Luke (2018). CHronic rhinosinusitis outcome MEasures (CHROME) – developing a core outcome set for trials of interventions in chronic rhinosinusitis. Rhinology, 56 (1), 22-32. doi: 10.4193/Rhino17.247
2017
Journal Article
Clinical Efficacy of a Topical Lactic Acid Bacterial Microbiome in Chronic Rhinosinusitis: A Randomized Controlled Trial
Martensson, Anders, Abolhalaj, Milad, Lindstedt, Malin, Martensson, Anette, Olofsson, Tobias C., Vasquez, Alejandra, Greiff, Lennart and Cervin, Anders (2017). Clinical Efficacy of a Topical Lactic Acid Bacterial Microbiome in Chronic Rhinosinusitis: A Randomized Controlled Trial. Laryngoscope Investigative Otolaryngology, 2 (6), 410-416. doi: 10.1002/lio2.93
2017
Journal Article
Tonsillectomy or tonsillotomy? A systematic review for paediatric sleep-disordered breathing
Zhang, Lai-Ying, Zhong, Laurie, David, Michael and Cervin, Anders (2017). Tonsillectomy or tonsillotomy? A systematic review for paediatric sleep-disordered breathing. International Journal of Pediatric Otorhinolaryngology, 103, 41-50. doi: 10.1016/j.ijporl.2017.10.008
2017
Journal Article
The effects of nasal lavage with betamethasone cream post-endoscopic sinus surgery: Clinical trial
Dawson, Blake, Gutteridge, I., Cervin, A. and Robinson, D. (2017). The effects of nasal lavage with betamethasone cream post-endoscopic sinus surgery: Clinical trial. Journal of Laryngology and Otology, 132 (2), 143-149. doi: 10.1017/S0022215117001827
2017
Journal Article
Quality of Life and Work Capacity Are Unrelated to Approach or Complications After Pituitary Surgery
Uvelius, Erik, Castelo, Nazia, Kahlon, Babar, Svensson, Christer, Cervin, Anders, Höglund, Peter, Valdemarsson, Stig and Siesjö, Peter (2017). Quality of Life and Work Capacity Are Unrelated to Approach or Complications After Pituitary Surgery. World Neurosurgery, 108, 24-32. doi: 10.1016/j.wneu.2017.08.087
2016
Conference Publication
Rising incidence of head and neck mucosal melanoma in Australia
Youssef, D., Vasani, S., Marquess, J. and Cervin, A. (2016). Rising incidence of head and neck mucosal melanoma in Australia. 65th Annual Scientific Meeting of the Australian-Society-of-Otolaryngology-Head-and-Neck-Surgery, Sydney Australia, Mar 07-10, 2015. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/S0022215116009385
2016
Journal Article
Chronic rhinosinusitis: a microbiome in dysbiosis and the search for alternative treatment options
Bordin, Amanda, Sidjabat, Hanna E., Cottrell, Kyra and Cervin, Anders (2016). Chronic rhinosinusitis: a microbiome in dysbiosis and the search for alternative treatment options. Microbiology Australia, 37 (3), 149-152. doi: 10.1071/MA16051
2016
Journal Article
Melioidosis in a patient with chronic rhinosinusitis
Phillips, N. M., Cervin, A., Earnshaw, J. and Sidjabat, H. E. (2016). Melioidosis in a patient with chronic rhinosinusitis. Journal of Laryngology and Otology, 130 (S4), S60-S62. doi: 10.1017/S0022215116008276
2016
Journal Article
Effects of a honeybee lactic acid bacterial microbiome on human nasal symptoms, commensals, and biomarkers
Martensson, Anders, Greiff, Lennart, Lamei, Sepideh S., Lindstedt, Malin, Olofsson, Tobias C., Vasquez, Alejandra and Cervin, Anders (2016). Effects of a honeybee lactic acid bacterial microbiome on human nasal symptoms, commensals, and biomarkers. International Forum of Allergy and Rhinology, 6 (9), 956-963. doi: 10.1002/alr.21762
2016
Journal Article
Draft genome sequence of the oral commensal Streptococcus oralis 89a with interference activity against respiratory pathogens
Sidjabat, Hanna E, Grahn Hakansson, Eva and Cervin, Anders (2016). Draft genome sequence of the oral commensal Streptococcus oralis 89a with interference activity against respiratory pathogens. Genome Announcements, 4 (1) e01546-15, e01546-15. doi: 10.1128/genomeA.01546-15
2015
Journal Article
Healthcare provider contact for children with symptoms of sleep-disordered breathing: a population survey
Gudnadottir, G., Ehnhage, A., Bende, M., Andersson, M., Cervin, A., Cardell, L.O. and Hellgren, J. (2015). Healthcare provider contact for children with symptoms of sleep-disordered breathing: a population survey. Journal of Laryngology and Otology, 130 (3), 296-301. doi: 10.1017/S0022215115003370
2015
Journal Article
Biological effects and clinical efficacy of a topical Toll-like receptor 7 agonist in seasonal allergic rhinitis: a parallel group controlled phase IIa study
Greiff, Lennart, Ahlström-Emanuelsson, Cecilia, Alenäs, Mikaela, Almqvist, Gun, Andersson, Morgan, Cervin, Anders, Dolata, Jan, Lindgren, Sam, Mårtensson, Anders, Young, Barbara and Widegren, Henrik (2015). Biological effects and clinical efficacy of a topical Toll-like receptor 7 agonist in seasonal allergic rhinitis: a parallel group controlled phase IIa study. Inflammation Research, 64 (11), 903-915. doi: 10.1007/s00011-015-0873-2
2015
Journal Article
Draft Genome Sequences of Burkholderia pseudomallei and Staphylococcus aureus, Isolated from a Patient with Chronic Rhinosinusitis
Sidjabat, Hanna E., Cottrell, Kyra and Cervin, Anders (2015). Draft Genome Sequences of Burkholderia pseudomallei and Staphylococcus aureus, Isolated from a Patient with Chronic Rhinosinusitis. Genome Announcements, 3 (5) e01075-15. doi: 10.1128/genomeA.01075-15
Supervision
Availability
- Honorary Professor Anders Cervin is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
Testing a sinonasal microbiome transplant as a therapy for Chronic Rhinosinusitis by randomised controlled trial
Principal Advisor
Other advisors: Dr Diane Maresco-Pennisi
Completed supervision
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2021
Doctor Philosophy
The microbiome of otitis media and development of a probiotic to prevent otitis media in Indigenous Australian children
Principal Advisor
Other advisors: Dr Seweryn Bialasiewicz
Media
Enquiries
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- sinusitis
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