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Pioneering stable copper carbanions for new C-C bond forming paradigms (2021-2024)

Abstract

The stabilisation of highly reactive carbanions underpins advances in chemical synthesis of new compounds including polymers, agrichemicals and pharmaceuticals. This project aims to deliver an innovative chemical reactivity platform, underpinned by copper carbanion complexes accessed via synthetic electrochemistry. Carbanions are essential components of carbon-carbon bond forming reactions but their high reactivity can be problematic. Expected outcomes of this project are an understanding of why these novel copper compounds are stable and how they can be utilised as synthetic reagents. This should provide significant benefits in unlocking the synthetic potential of a new class of chemical compound that has until now remained unexplored.

Experts

Professor Paul Bernhardt

Professor
School of Chemistry and Molecular Biosciences
Faculty of Science
Paul Bernhardt
Paul Bernhardt

Professor Craig Williams

Professor
School of Chemistry and Molecular Biosciences
Faculty of Science
Craig Williams
Craig Williams