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An integrated nano-bioengineered chip for enhanced molecular evolution (2022-2025)

Abstract

This project aims to develop a novel molecular evolution platform technology for the rapid selection of high value target binding molecules from diverse molecular libraries using an electrically activated nanofluidic chip coated with target. Significant outcomes from the project is the controlled selection of target binding molecules that is not possible with current methods and improved understanding of nanoforce driven molecular collisions on nano-bioengineered surfaces. This provides significant benefits, creating new knowledge in nanomaterials and advanced manufacturing of nanofabricated devices, creating commercial interest and positioning Australia at the forefront of molecular discovery technology, a highly valuable global market.

Experts

Professor Matt Trau

ARC Laureate Fellow and Senior Group Leader
Australian Institute for Bioengineering and Nanotechnology
Professor and ARC Laureate Fellow
School of Chemistry and Molecular Biosciences
Faculty of Science
Matt Trau
Matt Trau

Dr Selvakumar Edwardraja

Research Fellow
Australian Institute for Bioengineering and Nanotechnology
Selvakumar Edwardraja
Selvakumar Edwardraja

Dr Christopher Howard

Advance Qld Industry Res Fellow
Australian Institute for Bioengineering and Nanotechnology
Christopher Howard
Christopher Howard