Synthesis, Biological Interactions and Toxicity Studies of Precisely Engineered Nanoparticles (2008-2010)

This project brings together interdisciplinary expertise to examine how nanoparticles interact with biological systems. The project aims to synthesise precisely engineered nanoparticles, to characterise their physicochemical properties, and to examine their biological interaction and toxicity. We will analyse how size and surface properties define binding and uptake of nanoparticles into tissues, as well as their distribution in vivo. Importantly, this project will provide essential insight into the characteristics of nanomaterials that lead to adverse reactions and toxicity. The outcomes will benefit the development of nanotechnology by providing information to predict and possibly prevent unwanted nanoparticle effects.