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2024 Journal Article Sensitive label free imaging of 3D cell models with minimal toxicity using confocal reflectanceTaylor, Michael A., Choi, Jung Un Ally, Muthuswamy, Shiva, Martinez, Marco A. Enriquez, Lauko, Jan, Kijas, Amanda W. and Rowan, Alan E. (2024). Sensitive label free imaging of 3D cell models with minimal toxicity using confocal reflectance. Biomaterials Science, 12 (22), 5722-5727. doi: 10.1039/d4bm00304g |
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2024 Journal Article The potential of sugarcane waste-derived cellulose fibres as haemostatic agentsMalone, Siobhan, Yegappan, Ramanathan, Kijas, Amanda, Gemmell, Anna, Rowan, Alan, Rajah, Divya, Kim, Minjun, Lauko, Jan and Amiralian, Nasim (2024). The potential of sugarcane waste-derived cellulose fibres as haemostatic agents. Polymers, 16 (12) 1654. doi: 10.3390/polym16121654 |
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2023 Journal Article Entry and exit of extracellular vesicles to and from the blood circulationIannotta, Dalila, A, Amruta, Kijas, Amanda W., Rowan, Alan E. and Wolfram, Joy (2023). Entry and exit of extracellular vesicles to and from the blood circulation. Nature Nanotechnology, 19 (1), 137-20. doi: 10.1038/s41565-023-01522-z |
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2023 Journal Article Snake venom-defined fibrin architecture dictates fibroblast survival and differentiationWang, Zhao, Lauko, Jan, Kijas, Amanda W., Gilbert, Elliot P., Turunen, Petri, Yegappan, Ramanathan, Zou, Dongxiu, Mata, Jitendra and Rowan, Alan E. (2023). Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation. Nature Communications, 14 (1) 1029, 1-16. doi: 10.1038/s41467-023-36437-9 |
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2022 Journal Article Snake venom hydrogels as a rapid hemostatic agent for uncontrolled bleedingYegappan, Ramanathan, Lauko, Jan, Wang, Zhao, Lavin, Martin F., Kijas, Amanda W. and Rowan, Alan E. (2022). Snake venom hydrogels as a rapid hemostatic agent for uncontrolled bleeding. Advanced Healthcare Materials, 11 (15) 2200574, 2200574. doi: 10.1002/adhm.202200574 |
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2022 Journal Article The Mechanosensory Role of Osteocytes and Implications for Bone Health and Disease StatesChoi, Jung Un Ally, Kijas, Amanda W., Lauko, Jan and Rowan, Alan E. (2022). The Mechanosensory Role of Osteocytes and Implications for Bone Health and Disease States. Frontiers in Cell and Developmental Biology, 9 770143, 770143. doi: 10.3389/fcell.2021.770143 |
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2021 Journal Article Heterodyne Brillouin microscopy for biomechanical imagingTaylor, Michael A., Kijas, Amanda W., Wang, Zhao, Lauko, Jan and Rowan, Alan E. (2021). Heterodyne Brillouin microscopy for biomechanical imaging. Biomedical Optics Express, 12 (10) 6259, 6259-6268. doi: 10.1364/boe.435869 |
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2020 Journal Article Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responsesOvchinnikov, Dmitry A., Withey, Sarah L., Leeson, Hannah C., Lei, U. Wang, Sundarrajan, Ashmitha, Junday, Keerat, Pewarchuk, Michelle, Yeo, Abrey J., Kijas, Amanda W., Lavin, Martin F. and Wolvetang, Ernst J. (2020). Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responses. Human Molecular Genetics, 29 (6), 990-1001. doi: 10.1093/hmg/ddaa023 |
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2020 Journal Article Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophoreLim, Yi Chieh, Ensbey, Kathleen S., Offenhäuser, Carolin, D'souza, Rochelle C. J., Cullen, Jason K., Stringer, Brett W., Quek, Hazel, Bruce, Zara C., Kijas, Amanda, Cianfanelli, Valentina, Mahboubi, Bijan, Smith, Fiona, Jeffree, Rosalind L., Wiesmüeller, Lisa, Wiegmans, Adrian P., Bain, Amanda, Lombard, Fanny J., Roberts, Tara L., Khanna, Kum Kum, Lavin, Martin F., Kim, Baek, Hamerlik, Petra, Johns, Terrance G., Coster, Mark J., Boyd, Andrew W. and Day, Bryan W. (2020). Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore. Neuro-Oncology, 22 (2), 216-228. doi: 10.1093/neuonc/noz159 |
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2016 Journal Article Therapeutic targets and investigated treatments for Ataxia-TelangiectasiaLavin, Martin F., Yeo, Abrey J., Kijas, Amanda W., Wolvetang, Ernst, Sly, Peter D., Wainwright, Claire and Sinclair, Kate (2016). Therapeutic targets and investigated treatments for Ataxia-Telangiectasia. Expert Opinion on Orphan Drugs, 4 (12), 1263-1276. doi: 10.1080/21678707.2016.1254618 |
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2015 Journal Article ATM-dependent phosphorylation of all three members of the MRN complex: from sensor to adaptorLavin, Martin F., Kozlov, Sergei, Gatei, Magtouf and Kijas, Amanda W. (2015). ATM-dependent phosphorylation of all three members of the MRN complex: from sensor to adaptor. Biomolecules, 5 (4) A31, 2877-2902. doi: 10.3390/biom5042877 |
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2015 Journal Article ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1Kijas, Amanda W., Lim, Yi Chieh, Bolderson, Emma, Cerosaletti, Karen, Gatei, Magtouf, Jakob, Burkhard, Tobias, Frank, Taucher-Scholz, Gisela, Gueven, Nuri, Oakley, Greg, Concannon, Patrick, Wolvetang, Ernst, Khanna, Kum Kum, Wiesmuller, Lisa and Lavin, Martin F. (2015). ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1. Nucleic Acids Research, 43 (17), 8352-8367. doi: 10.1093/nar/gkv754 |
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2014 Journal Article RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stressGatei, Magtouf, Kijas, Amanda W., Biard, Denis, Dork, Thilo and Lavin, Martin F. (2014). RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress. Human Molecular Genetics, 23 (16) ddu141, 4232-4248. doi: 10.1093/hmg/ddu141 |
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2013 Journal Article A patient-derived olfactory stem cell disease model for ataxia-telangiectasiaStewart, Romal, Kozlov, Sergei, Matigian, Nicholas, Wali, Gautam, Gatei, Magtouf, Sutharsan, Ratneswary, Bellette, Bernadette, Kijas, Amanda Wraith, Cochrane, Julie, Coulthard, Mark, Perry, Chris, Sinclair, Kate, Mackay-Sim, Alan and Lavin, Martin F. (2013). A patient-derived olfactory stem cell disease model for ataxia-telangiectasia. Human Molecular Genetics, 22 (12), 2495-2509. doi: 10.1093/hmg/ddt101 |
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2012 Journal Article A role for homologous recombination and abnormal cell-cycle progression in radioresistance of glioma-initiating cellsLim, Yi Chieh, Roberts, Tara L., Day, Bryan W., Harding, Angus, Kozlov, Sergei, Kijas, Amanda W., Ensbey, Kathleen S., Walker, David G. and Lavin, Martin F. (2012). A role for homologous recombination and abnormal cell-cycle progression in radioresistance of glioma-initiating cells. Molecular Cancer Therapeutics, 11 (9), 1863-1872. doi: 10.1158/1535-7163.MCT-11-1044 |
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2011 Journal Article ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle controlGatei, Magtouf, Jakob, Burkhard, Chen, Philip, Kijas, Amanda W., Becherel, Olivier J., Gueven, Nuri, Birrell, Geoff, Lee, Ji-Hoon, Paull, Tanya T., Lerenthal, Yaniv, Fazry, Shazrul, Taucher-Scholtz, Gisela, Kalb, Reinhard, Schindler, Detlev, Waltes, Regina, Doerk, Thilo and Lavin, Martin F. (2011). ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control. Journal of Biological Chemistry, 286 (36), 31542-31556. doi: 10.1074/jbc.M111.258152 |
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2011 Journal Article Autophosphorylation and ATM activation: Additional sites add to the complexityKozlov, Sergei V., Graham, Mark E., Jakob, Burkhard, Tobias, Frank, Kijas, Amanda W., Tanuji, Marcel, Chen, Philip, Robinson, Phillip J., Taucher-Scholz, Gisela, Suzuki, Keiji, So, Sairai, Chen, David and Lavin, Martin F. (2011). Autophosphorylation and ATM activation: Additional sites add to the complexity. The Journal of Biological Chemistry, 286 (11), 9107-9119. doi: 10.1074/jbc.M110.204065 |
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2010 Journal Article CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage responseBecherel, Olivier J., Jakob, Burkhard, Cherry, Amy L., Gueven, Nuri, Fusser, Markus, Kijas, Amanda W., Peng, Cheng, Katyal, Sachin, McKinnon, Peter J., Chen, Junjie, Epe, Bernd, Smerdon, Stephen J., Taucher-Scholz, Gisela and Lavin, Martin F. (2010). CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response. Nucleic Acids Research, 38 (5) gkp1149, 1489-1503. doi: 10.1093/nar/gkp1149 |
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2009 Journal Article Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder.Waltes, R, Kalb, R, Gatei, M, Kijas, AW, Stumm, M, Sobeck, A, Wieland, B, Varon, R, Lerenthal Y, Lavin, Martin F., Schindler, D and Dörk, T (2009). Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder.. American Journal of Human Genetics, 84 (5), 605-616. doi: 10.1016/j.ajhg.2009.04.010 |
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2007 Journal Article A subgroup of spinocerebellar ataxias defective in DNA damage responsesGueven, N., Chen, P., Nakamura, J., Becherel, O.J., Kijas, A.W., Grattan-Smith, P. and Lavin, M.F. (2007). A subgroup of spinocerebellar ataxias defective in DNA damage responses. Neuroscience, 145 (4), 1418-1425. doi: 10.1016/j.neuroscience.2006.12.010 |
