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2024

Journal Article

The effect of a dominant kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy on brain development and neuropathology

Stables, Jennifer, Pal, Reiss, Bradford, Barry M., Carter-Cusack, Dylan, Taylor, Isis, Pridans, Clare, Khan, Nemat, Woodruff, Trent M., Irvine, Katharine M., Summers, Kim M., Mabbott, Neil A. and Hume, David A. (2024). The effect of a dominant kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy on brain development and neuropathology. Neurobiology of Disease, 203 106743, 106743. doi: 10.1016/j.nbd.2024.106743

The effect of a dominant kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy on brain development and neuropathology

2024

Conference Publication

Development of venom peptide inhibitors of acid-sensing ion channel 1 as novel therapeutics for multiple sclerosis

Rash, Lachlan, Waqar, Maleeha, Butcher, Neville and Khan, Nemat (2024). Development of venom peptide inhibitors of acid-sensing ion channel 1 as novel therapeutics for multiple sclerosis. Multiple Sclerosis Australia: Progress in MS Research Conference (MS), Perth, WA, Australia, 29 November-1 December 2023. London, United Kingdom: Sage Publications.

Development of venom peptide inhibitors of acid-sensing ion channel 1 as novel therapeutics for multiple sclerosis

2024

Conference Publication

Insights into the role of acid sensing ion channels in the pathophysiology of multiple sclerosis

Waqar, Maleeha, Khan, Nemat, Butcher, Neville and Rash, Lachlan (2024). Insights into the role of acid sensing ion channels in the pathophysiology of multiple sclerosis. Multiple Sclerosis Australia: Progress in MS Research Conference (MS), Perth, WA, Australia, 29 November-1 December 2023. London, United Kingdom: Sage Publications.

Insights into the role of acid sensing ion channels in the pathophysiology of multiple sclerosis

2024

Conference Publication

Understanding the role of acid sensing ion channels as targets of neuroprotection in the pathophysiology of multiple sclerosis

Waqar, Maleeha, Rash, Lachlan, Butcher, Neville and Khan, Nemat (2024). Understanding the role of acid sensing ion channels as targets of neuroprotection in the pathophysiology of multiple sclerosis. 40th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Copenhagen, Denmark, 18-20 September 2024. London, United Kingdom: Sage Publications. doi: 10.1177/13524585241269220

Understanding the role of acid sensing ion channels as targets of neuroprotection in the pathophysiology of multiple sclerosis

2024

Conference Publication

Developing novel acid-sensing ion channel inhibitor as a neuroprotective lead for multiple sclerosis

Khan, Nemat, Waqar, Maleeha, Butcher, Neville and Rash, Lachlan (2024). Developing novel acid-sensing ion channel inhibitor as a neuroprotective lead for multiple sclerosis. 40th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Copenhagen, Denmark, 18-20 September 2024. London, United Kingdom: Sage Publications. doi: 10.1177/13524585241269220

Developing novel acid-sensing ion channel inhibitor as a neuroprotective lead for multiple sclerosis

2024

Journal Article

Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction

Redd, Meredith A, Yoshikawa, Yusuke, Khan, Nemat, Waqar, Maleeha, Saez, Natalie J, Outhwaite, Jennifer E, Russell, Jake S, Hanna, Amy D, Chiu, Han S, Er, Sing Yan, Butcher, Neville J, Mardon, Karine, Fraser, John F, Smythe, Mark L, Rash, Lachlan D, Thomas, Walter G, King, Glenn F, Reichelt, Melissa E and Palpant, Nathan J (2024). Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction. European Heart Journal, 45 (17), 1571-1574. doi: 10.1093/eurheartj/ehad793

Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction

2024

Journal Article

Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis

Khan, Nemat, Kumar, Vinod, Li, Pengcheng, RAPIDS Study Group, Raman, Sainath (RSG member), Sharp, Natalie (RSG member), Irwin, Adam (RSG member), Phillips, Natalie (RSG member), George, Shane (RSG member), Grimwood, Keith (RSG member), Snelling, Peter (RSG member), Chavan, Arjun (RSG member), Hempenstall, Allison (RSG member), Gibbons, Kristen (RSG member), Le Marsney, Renate (RSG member), Blumenthal, Antje (RSG member), Ganesamoorthy, Devika (RSG member), Coin, Lachlan (RSG member), Schlapbach, Luregn J., Boyd, Andrew W., Coulthard, Mark G. and Woodruff, Trent M. (2024). Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis. Science Translational Medicine, 16 (744) eadg5768, 1-15. doi: 10.1126/scitranslmed.adg5768

Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis

2024

Journal Article

Transient binocular vision loss and pain insensitivity in Klippel–Feil syndrome: a case report

Ullah, Zeeshan, Zafar, Ayesha, Ishaq, Hira, Umar, Zainab, Khan, Amir, Badar, Yaseen, Din, Nizamud, Khan, Muhammad Fawad, McCombe, Pamela and Khan, Nemat (2024). Transient binocular vision loss and pain insensitivity in Klippel–Feil syndrome: a case report. Journal of Medical Case Reports, 18 (1) 137, 1-6. doi: 10.1186/s13256-024-04374-w

Transient binocular vision loss and pain insensitivity in Klippel–Feil syndrome: a case report

2024

Book Chapter

Targeting acid-sensing ion channels in disease

Senescall, Victor, Budusan, Elena, Knezic, Adriana, Waqar, Maleeha, Butcher, Neville, Khan, Nemat, McCarthy, Claudia, Widopp, Robert, Karatt-Vellat, Aneesh and Rash, Lachlan D. (2024). Targeting acid-sensing ion channels in disease. Ion channels as targets in drug discovery. (pp. 303-355) edited by Gary Stephens and Edward Stevens. Cham, Switzerland: Springer. doi: 10.1007/978-3-031-52197-3_10

Targeting acid-sensing ion channels in disease

2023

Journal Article

Multi-parametric MR for detection of pathological changes in CNS of mouse model of multiple sclerosis in vivo

Althobity, Abdullah A., Khan, Nemat, Sandrock, Cheyenne J., Woodruff, Trent M, Cowin, Gary J., Brereton, Ian M. and Kurniawan, Nyoman D. (2023). Multi-parametric MR for detection of pathological changes in CNS of mouse model of multiple sclerosis in vivo. NMR in Biomedicine, 36 (10) e4964, e4964. doi: 10.1002/nbm.4964

Multi-parametric MR for detection of pathological changes in CNS of mouse model of multiple sclerosis in vivo

2022

Journal Article

Carbohydrate polymer-based targeted pharmaceutical formulations for colorectal cancer: systematic review of the literature

Farhaj, Samia, Agbotui, Theodora L., Nirwan, Jorabar Singh, Mahmood, Qaisar, Yousaf, Abid Mehmood, Hussain, Talib, Shahzad, Yasser, Khan, Nemat, Conway, Barbara R. and Ghori, Muhammad Usman (2022). Carbohydrate polymer-based targeted pharmaceutical formulations for colorectal cancer: systematic review of the literature. Polysaccharides, 3 (4), 692-714. doi: 10.3390/polysaccharides3040040

Carbohydrate polymer-based targeted pharmaceutical formulations for colorectal cancer: systematic review of the literature

2022

Journal Article

Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain

Kong, Dehui, Saqer, Alaa A., Carpinelli de Jesus, Matheus, Khan, Nemat, Jones, Alun, Blanchfield, Joanne T., Smith, Maree T. and Williams, Craig M. (2022). Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain. Bioorganic and Medicinal Chemistry, 69 116889, 1-10. doi: 10.1016/j.bmc.2022.116889

Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain

2022

Journal Article

β-Glucan receptors on IL-4 activated macrophages are required for hookworm larvae recognition and trapping

Bouchery, Tiffany, Volpe, Beatrice, Doolan, Rory, Coakley, Gillian, Moyat, Mati, Esser-von Bieren, Julia, Wickramasinghe, Lakshanie C, Hibbs, Margaret L, Sotillo, Javier, Camberis, Mali, Le Gros, Graham, Khan, Nemat, Williams, David and Harris, Nicola L (2022). β-Glucan receptors on IL-4 activated macrophages are required for hookworm larvae recognition and trapping. Immunology and Cell Biology, 100 (4), 223-234. doi: 10.1111/imcb.12536

β-Glucan receptors on IL-4 activated macrophages are required for hookworm larvae recognition and trapping

2021

Journal Article

Post-COVID opsoclonus myoclonus syndrome: a case report from Pakistan

Ishaq, Hira, Durrani, Talha, Umar, Zainab, Khan, Nemat, McCombe, Pamela and Ul Haq, Mian Ayaz (2021). Post-COVID opsoclonus myoclonus syndrome: a case report from Pakistan. Frontiers in Neurology, 12 672524, 672524. doi: 10.3389/fneur.2021.672524

Post-COVID opsoclonus myoclonus syndrome: a case report from Pakistan

2021

Journal Article

Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods

Park, Thomas S.W., Khan, Nemat, Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2021). Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods. Clinical and Experimental Pharmacology and Physiology, 48 (1) 1440-1681.13402, 96-106. doi: 10.1111/1440-1681.13402

Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods

2020

Journal Article

Comparative studies of glial fibrillary acidic protein and brain‐derived neurotrophic factor expression in two transgenic mouse models of Alzheimer’s disease

Edwards, Stephen R., Khan, Nemat, Coulson, Elizabeth J. and Smith, Maree T. (2020). Comparative studies of glial fibrillary acidic protein and brain‐derived neurotrophic factor expression in two transgenic mouse models of Alzheimer’s disease. Clinical and Experimental Pharmacology and Physiology, 47 (10) 1440-1681.13363, 1740-1750. doi: 10.1111/1440-1681.13363

Comparative studies of glial fibrillary acidic protein and brain‐derived neurotrophic factor expression in two transgenic mouse models of Alzheimer’s disease

2019

Journal Article

J-2156, a somatostatin receptor type 4 agonist, alleviates mechanical hyperalgesia in a rat model of chronic low back pain

Park, Thomas S.W., Khan, Nemat, Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2019). J-2156, a somatostatin receptor type 4 agonist, alleviates mechanical hyperalgesia in a rat model of chronic low back pain. Biomedicine and Pharmacotherapy, 117 109056, 109056. doi: 10.1016/j.biopha.2019.109056

J-2156, a somatostatin receptor type 4 agonist, alleviates mechanical hyperalgesia in a rat model of chronic low back pain

2018

Journal Article

The somatostatin receptor-4 agonist J-2156 alleviates mechanical hypersensitivity in a rat model of breast cancer induced bone pain

Shenoy, Priyank A., Kuo, Andy, Khan, Nemat, Gorham, Louise, Nicholson, Janet, Corradini, Laura, Vetter, Irina and Smith, Maree T. (2018). The somatostatin receptor-4 agonist J-2156 alleviates mechanical hypersensitivity in a rat model of breast cancer induced bone pain. Frontiers in Pharmacology, 9 (MAY) 495, 495. doi: 10.3389/fphar.2018.00495

The somatostatin receptor-4 agonist J-2156 alleviates mechanical hypersensitivity in a rat model of breast cancer induced bone pain

2017

Journal Article

Attenuation of the Infiltration of Angiotensin II Expressing CD3(+) T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia - A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT(2)) Receptor Antagonist

Khan, Nemat, Muralidharan, Arjun and Smith, Maree T. (2017). Attenuation of the Infiltration of Angiotensin II Expressing CD3(+) T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia - A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT(2)) Receptor Antagonist. Frontiers in Molecular Neuroscience, 10 389, 389. doi: 10.3389/fnmol.2017.00389

Attenuation of the Infiltration of Angiotensin II Expressing CD3(+) T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia - A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT(2)) Receptor Antagonist

2017

Journal Article

Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain

Khan, Nemat, Kuo, Andy, Brockman, David A, Cooper, Matthew A and Smith, Maree T (2017). Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain. Inflammopharmacology, 26 (1), 77-86. doi: 10.1007/s10787-017-0401-9

Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain