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2024 Journal Article The effect of a dominant kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy on brain development and neuropathologyStables, Jennifer, Pal, Reiss, Bradford, Barry M., Carter-Cusack, Dylan, Taylor, Isis, Pridans, Clare, Khan, Nemat, Woodruff, Trent M., Irvine, Katharine M., Summers, Kim M., Mabbott, Neil A. and Hume, David A. (2024). The effect of a dominant kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy on brain development and neuropathology. Neurobiology of Disease, 203 106743, 106743. doi: 10.1016/j.nbd.2024.106743 |
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2024 Journal Article Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarctionRedd, Meredith A, Yoshikawa, Yusuke, Khan, Nemat, Waqar, Maleeha, Saez, Natalie J, Outhwaite, Jennifer E, Russell, Jake S, Hanna, Amy D, Chiu, Han S, Er, Sing Yan, Butcher, Neville J, Mardon, Karine, Fraser, John F, Smythe, Mark L, Rash, Lachlan D, Thomas, Walter G, King, Glenn F, Reichelt, Melissa E and Palpant, Nathan J (2024). Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction. European Heart Journal, 45 (17), 1571-1574. doi: 10.1093/eurheartj/ehad793 |
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2024 Journal Article Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsisKhan, Nemat, Kumar, Vinod, Li, Pengcheng, RAPIDS Study Group, Raman, Sainath (RSG member), Sharp, Natalie (RSG member), Irwin, Adam (RSG member), Phillips, Natalie (RSG member), George, Shane (RSG member), Grimwood, Keith (RSG member), Snelling, Peter (RSG member), Chavan, Arjun (RSG member), Hempenstall, Allison (RSG member), Gibbons, Kristen (RSG member), Le Marsney, Renate (RSG member), Blumenthal, Antje (RSG member), Ganesamoorthy, Devika (RSG member), Coin, Lachlan (RSG member), Schlapbach, Luregn J., Boyd, Andrew W., Coulthard, Mark G. and Woodruff, Trent M. (2024). Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis. Science Translational Medicine, 16 (744) eadg5768, 1-15. doi: 10.1126/scitranslmed.adg5768 |
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2024 Journal Article Transient binocular vision loss and pain insensitivity in Klippel–Feil syndrome: a case reportUllah, Zeeshan, Zafar, Ayesha, Ishaq, Hira, Umar, Zainab, Khan, Amir, Badar, Yaseen, Din, Nizamud, Khan, Muhammad Fawad, McCombe, Pamela and Khan, Nemat (2024). Transient binocular vision loss and pain insensitivity in Klippel–Feil syndrome: a case report. Journal of Medical Case Reports, 18 (1) 137, 1-6. doi: 10.1186/s13256-024-04374-w |
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2023 Journal Article Multi-parametric MR for detection of pathological changes in CNS of mouse model of multiple sclerosis in vivoAlthobity, Abdullah A., Khan, Nemat, Sandrock, Cheyenne J., Woodruff, Trent M, Cowin, Gary J., Brereton, Ian M. and Kurniawan, Nyoman D. (2023). Multi-parametric MR for detection of pathological changes in CNS of mouse model of multiple sclerosis in vivo. NMR in Biomedicine, 36 (10) e4964, e4964. doi: 10.1002/nbm.4964 |
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2022 Journal Article Carbohydrate polymer-based targeted pharmaceutical formulations for colorectal cancer: systematic review of the literatureFarhaj, Samia, Agbotui, Theodora L., Nirwan, Jorabar Singh, Mahmood, Qaisar, Yousaf, Abid Mehmood, Hussain, Talib, Shahzad, Yasser, Khan, Nemat, Conway, Barbara R. and Ghori, Muhammad Usman (2022). Carbohydrate polymer-based targeted pharmaceutical formulations for colorectal cancer: systematic review of the literature. Polysaccharides, 3 (4), 692-714. doi: 10.3390/polysaccharides3040040 |
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2022 Journal Article Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic painKong, Dehui, Saqer, Alaa A., Carpinelli de Jesus, Matheus, Khan, Nemat, Jones, Alun, Blanchfield, Joanne T., Smith, Maree T. and Williams, Craig M. (2022). Design, synthesis and evaluation of alpha lipoic acid derivatives to treat multiple sclerosis-associated central neuropathic pain. Bioorganic and Medicinal Chemistry, 69 116889, 1-10. doi: 10.1016/j.bmc.2022.116889 |
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2022 Journal Article β-Glucan receptors on IL-4 activated macrophages are required for hookworm larvae recognition and trappingBouchery, Tiffany, Volpe, Beatrice, Doolan, Rory, Coakley, Gillian, Moyat, Mati, Esser-von Bieren, Julia, Wickramasinghe, Lakshanie C, Hibbs, Margaret L, Sotillo, Javier, Camberis, Mali, Le Gros, Graham, Khan, Nemat, Williams, David and Harris, Nicola L (2022). β-Glucan receptors on IL-4 activated macrophages are required for hookworm larvae recognition and trapping. Immunology and Cell Biology, 100 (4), 223-234. doi: 10.1111/imcb.12536 |
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2021 Journal Article Post-COVID opsoclonus myoclonus syndrome: a case report from PakistanIshaq, Hira, Durrani, Talha, Umar, Zainab, Khan, Nemat, McCombe, Pamela and Ul Haq, Mian Ayaz (2021). Post-COVID opsoclonus myoclonus syndrome: a case report from Pakistan. Frontiers in Neurology, 12 672524, 672524. doi: 10.3389/fneur.2021.672524 |
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2021 Journal Article Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methodsPark, Thomas S.W., Khan, Nemat, Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2021). Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods. Clinical and Experimental Pharmacology and Physiology, 48 (1) 1440-1681.13402, 96-106. doi: 10.1111/1440-1681.13402 |
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2020 Journal Article Comparative studies of glial fibrillary acidic protein and brain‐derived neurotrophic factor expression in two transgenic mouse models of Alzheimer’s diseaseEdwards, Stephen R., Khan, Nemat, Coulson, Elizabeth J. and Smith, Maree T. (2020). Comparative studies of glial fibrillary acidic protein and brain‐derived neurotrophic factor expression in two transgenic mouse models of Alzheimer’s disease. Clinical and Experimental Pharmacology and Physiology, 47 (10) 1440-1681.13363, 1740-1750. doi: 10.1111/1440-1681.13363 |
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2019 Journal Article J-2156, a somatostatin receptor type 4 agonist, alleviates mechanical hyperalgesia in a rat model of chronic low back painPark, Thomas S.W., Khan, Nemat, Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2019). J-2156, a somatostatin receptor type 4 agonist, alleviates mechanical hyperalgesia in a rat model of chronic low back pain. Biomedicine and Pharmacotherapy, 117 109056, 109056. doi: 10.1016/j.biopha.2019.109056 |
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2018 Journal Article The somatostatin receptor-4 agonist J-2156 alleviates mechanical hypersensitivity in a rat model of breast cancer induced bone painShenoy, Priyank A., Kuo, Andy, Khan, Nemat, Gorham, Louise, Nicholson, Janet, Corradini, Laura, Vetter, Irina and Smith, Maree T. (2018). The somatostatin receptor-4 agonist J-2156 alleviates mechanical hypersensitivity in a rat model of breast cancer induced bone pain. Frontiers in Pharmacology, 9 (MAY) 495, 495. doi: 10.3389/fphar.2018.00495 |
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2017 Journal Article Attenuation of the Infiltration of Angiotensin II Expressing CD3(+) T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia - A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT(2)) Receptor AntagonistKhan, Nemat, Muralidharan, Arjun and Smith, Maree T. (2017). Attenuation of the Infiltration of Angiotensin II Expressing CD3(+) T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia - A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT(2)) Receptor Antagonist. Frontiers in Molecular Neuroscience, 10 389, 389. doi: 10.3389/fnmol.2017.00389 |
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2017 Journal Article Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic painKhan, Nemat, Kuo, Andy, Brockman, David A, Cooper, Matthew A and Smith, Maree T (2017). Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain. Inflammopharmacology, 26 (1), 77-86. doi: 10.1007/s10787-017-0401-9 |
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2015 Journal Article Neurotrophins and neuropathic pain: role in pathobiologyKhan, Nemat and Smith, Maree T. (2015). Neurotrophins and neuropathic pain: role in pathobiology. Molecules, 20 (6), 10657-10688. doi: 10.3390/molecules200610657 |
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2015 Journal Article Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signalling in the dorsal horn of the spinal cordKhan, Nemat, Gordon, Richard, Woodruff, Trent M. and Smith, Maree T. (2015). Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signalling in the dorsal horn of the spinal cord. Pharmacology Research and Perspectives, 3 (3) e00137, 1-16. doi: 10.1002/prp2.137 |
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2014 Journal Article Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methodsKhan, Nemat, Woodruff, Trent M. and Smith, Maree T. (2014). Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods. Pharmacology Biochemistry and Behavior, 126, 13-27. doi: 10.1016/j.pbb.2014.09.003 |
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2013 Journal Article Multiple sclerosis-induced neuropathic pain: pharmacological management and pathophysiological insights from rodent EAE modelsKhan, Nemat and Smith, Maree T. (2013). Multiple sclerosis-induced neuropathic pain: pharmacological management and pathophysiological insights from rodent EAE models. Inflammopharmacology, 22 (1), 1-22. doi: 10.1007/s10787-013-0195-3 |
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2012 Journal Article Molecular simulations of bergenin as a new urease inhibitorArfan, Mohammad, Amin, Hazrat, Khan, Inamullah, Shah, Muhammad Raza, Shah, Hamidullah, Khan, Amir Zada, Halimi, Syed Muhammad Ashhad, Khan, Nematullah, Kaleem, Waqar Ahmad, Qayum, Mughal, Shahidullah, Adnan and Khan, Muhammad Azam (2012). Molecular simulations of bergenin as a new urease inhibitor. Medicinal Chemistry Research, 21 (9), 2454-2457. doi: 10.1007/s00044-011-9762-6 |
