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2020

Journal Article

Semisynthetic, self-adjuvanting vaccine development: efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccine

Xu, Zhenghui, Rivera-Hernandez, Tania, Chatterjee, Oishee, Walker, Mark J. and Moyle, Peter M. (2020). Semisynthetic, self-adjuvanting vaccine development: efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccine. Journal of Controlled Release, 317, 96-108. doi: 10.1016/j.jconrel.2019.11.018

Semisynthetic, self-adjuvanting vaccine development: efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccine

2020

Journal Article

A self‐adjuvanting vaccine platform: optimization of site‐specific sortase a mediated conjugation of toll‐like receptor 2 ligands onto the carboxyl or amino terminus of recombinant protein antigens

Xu, Zhenghui and Moyle, Peter Michael (2020). A self‐adjuvanting vaccine platform: optimization of site‐specific sortase a mediated conjugation of toll‐like receptor 2 ligands onto the carboxyl or amino terminus of recombinant protein antigens. ChemPlusChem, 85 (1), 227-236. doi: 10.1002/cplu.201900687

A self‐adjuvanting vaccine platform: optimization of site‐specific sortase a mediated conjugation of toll‐like receptor 2 ligands onto the carboxyl or amino terminus of recombinant protein antigens

2019

Journal Article

Soil bacterial diffusible and volatile organic compounds inhibit Phytophthora capsici and promote plant growth

Syed-Ab-Rahman, Sharifah Farhana, Carvalhais, Lilia C., Chua, Elvis T., Chung, Fong Yi, Moyle, Peter M., Eltanahy, Eladl G. and Schenk, Peer M. (2019). Soil bacterial diffusible and volatile organic compounds inhibit Phytophthora capsici and promote plant growth. Science of the Total Environment, 692, 267-280. doi: 10.1016/j.scitotenv.2019.07.061

Soil bacterial diffusible and volatile organic compounds inhibit Phytophthora capsici and promote plant growth

2019

Journal Article

Peptide-based targeted polymeric nanoparticles for siRNA delivery

Hussein, Waleed M., Cheong, Yee S., Liu, Chang, Liu, Genan, Begum, Anjuman Ara, Attallah, Maria Adly, Moyle, Peter Michael, Torchilin, Vladimir, Smith, Roger and Toth, Istvan (2019). Peptide-based targeted polymeric nanoparticles for siRNA delivery. Nanotechnology, 30 (41) 415604, 415604. doi: 10.1088/1361-6528/ab313d

Peptide-based targeted polymeric nanoparticles for siRNA delivery

2019

Journal Article

Advances in targeted gene delivery

Begum, Anjuman A., Toth, Istvan, Hussein, Waleed M. and Moyle, Peter Michael (2019). Advances in targeted gene delivery. Current Drug Delivery, 16 (7), 588-608. doi: 10.2174/1567201816666190529072914

Advances in targeted gene delivery

2019

Journal Article

Gastrin-releasing peptide receptor-targeted hybrid peptide/phospholipid pDNA/siRNA delivery systems

Begum, Anjuman A., Toth, Istvan and Moyle, Peter M. (2019). Gastrin-releasing peptide receptor-targeted hybrid peptide/phospholipid pDNA/siRNA delivery systems. Nanomedicine, 14 (9), 1153-1171. doi: 10.2217/nnm-2018-0380

Gastrin-releasing peptide receptor-targeted hybrid peptide/phospholipid pDNA/siRNA delivery systems

2019

Journal Article

Glucagon-like peptide-1 receptor agonists and strategies to improve their efficiency

Alavi, Seyed Ebrahim, Cabot, Peter J. and Moyle, Peter M. (2019). Glucagon-like peptide-1 receptor agonists and strategies to improve their efficiency. Molecular Pharmaceutics, 16 (6) acs.molpharmaceut.9b00308, 2278-2295. doi: 10.1021/acs.molpharmaceut.9b00308

Glucagon-like peptide-1 receptor agonists and strategies to improve their efficiency

2019

Journal Article

Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology

Maqbool, Faheem, Moyle, Peter M., Thurecht, Kristofer J. and Falconer, James R. (2019). Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology. International Journal of Pharmaceutics, 563, 174-183. doi: 10.1016/j.ijpharm.2019.03.053

Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology

2019

Journal Article

An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model

Rivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2019). An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model. mBio, 10 (2) e00693-19. doi: 10.1128/mBio.00693-19

An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model

2019

Journal Article

Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing

Maqbool, Faheem, Moyle, Peter M., Tan, Madeleine S. A., Thurecht, Kristofer J. and Falconer, James R. (2019). Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing. Artificial Cells, Nanomedicine, and Biotechnology, 46 (sup3), 1-7. doi: 10.1080/21691401.2018.1536059

Preparation of albendazole-loaded liposomes by supercritical carbon dioxide processing

2018

Journal Article

Glucagon-like peptide-1 (GLP-1)-based therapeutics: current status and future opportunities beyond type 2 diabetes

Cheang, Jia Ying and Moyle, Peter Michael (2018). Glucagon-like peptide-1 (GLP-1)-based therapeutics: current status and future opportunities beyond type 2 diabetes. ChemMedChem, 13 (7), 662-671. doi: 10.1002/cmdc.201700781

Glucagon-like peptide-1 (GLP-1)-based therapeutics: current status and future opportunities beyond type 2 diabetes

2018

Journal Article

Bombesin/oligoarginine fusion peptides for gastrin releasing peptide receptor (GRPR) targeted gene delivery

Begum, Anjuman Ara, Wan, Yu, Toth, Istvan and Moyle, Peter M. (2018). Bombesin/oligoarginine fusion peptides for gastrin releasing peptide receptor (GRPR) targeted gene delivery. Bioorganic and Medicinal Chemistry, 26 (2), 516-526. doi: 10.1016/j.bmc.2017.12.013

Bombesin/oligoarginine fusion peptides for gastrin releasing peptide receptor (GRPR) targeted gene delivery

2017

Journal Article

Bioconjugation approaches to produce subunit vaccines composed of protein or peptide antigens and covalently attached toll-like receptor ligands

Xu, Zhenghui and Moyle, Peter Michael (2017). Bioconjugation approaches to produce subunit vaccines composed of protein or peptide antigens and covalently attached toll-like receptor ligands. Bioconjugate Chemistry, 29 (3), 572-586. doi: 10.1021/acs.bioconjchem.7b00478

Bioconjugation approaches to produce subunit vaccines composed of protein or peptide antigens and covalently attached toll-like receptor ligands

2017

Journal Article

Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells

Wan, Yu, Dai, Wei, Nevagi, Reshma J., Toth, Istvan and Moyle, Peter M. (2017). Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells. Acta Biomaterialia, 59, 257-268. doi: 10.1016/j.actbio.2017.06.032

Multifunctional peptide-lipid nanocomplexes for efficient targeted delivery of DNA and siRNA into breast cancer cells

2017

Journal Article

Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery.

Wan, Yu, Moyle, Peter M., Gn, Pei Z. and Toth, Istvan (2017). Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery.. Nanomedicine, 12 (4), 281-293. doi: 10.2217/nnm-2016-0354

Design and evaluation of a stearylated multicomponent peptide-siRNA nanocomplex for efficient cellular siRNA delivery.

2016

Journal Article

Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor

Begum, Anjuman Ara, Moyle, Peter M. and Toth, Istvan (2016). Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor. Bioorganic and Medicinal Chemistry, 24 (22), 5834-5841. doi: 10.1016/j.bmc.2016.09.039

Investigation of Bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor

2016

Journal Article

Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA delivery

Kamaruzaman, Khairul A., Moyle, Peter M. and Toth, Istvan (2016). Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA delivery. International Journal of Peptide Research and Therapeutics, 23 (1), 1-16. doi: 10.1007/s10989-016-9545-5

Peptide-based multicomponent oligonucleotide delivery systems: optimisation of poly-l-lysine dendrons for plasmid DNA delivery

2016

Journal Article

Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models

Rivera-Hernandez, Tania, Pandey, Manisha, Henningham, Anna, Cole, Jason, Choudhury, Biswa, Cork, Amanda J., Gillen, Christine M., Ghaffar, Khairunnisa Abdul, West, Nicholas P., Silvestri, Guido, Good, Michael F., Moyle, Peter M., Toth, Istvan, Nizet, Victor, Batzloff, Michael R. and Walker, Mark J. (2016). Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models. mBio, 7 (3) e00618-16, e00618-16.1-e00618-16.9. doi: 10.1128/mBio.00618-16

Differing efficacies of lead Group A Streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models

2016

Journal Article

Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity

Wan, Yu, Moyle, Peter M., Christie, Michelle P. and Toth, Istvan (2016). Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity. Nanomedicine, 11 (8), 907-919. doi: 10.2217/nnm.16.27

Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity

2016

Journal Article

Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines

Hussein, Waleed M., Liu, Tzu-Yu, Maruthayanar, Pirashanthini, Mukaida, Saori, Moyle, Peter M., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2016). Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines. Chemical Science, 7 (3), 2308-2321. doi: 10.1039/C5SC03859F

Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines