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2015

Journal Article

Endosome escape strategies for improving the efficacy of oligonucleotide delivery systems

Wan, Yu, Moyle, Peter M and Toth, Istvan (2015). Endosome escape strategies for improving the efficacy of oligonucleotide delivery systems. Current Medicinal Chemistry, 22 (29), 3326-3346. doi: 10.2174/0929867322666150825162941

Endosome escape strategies for improving the efficacy of oligonucleotide delivery systems

2015

Journal Article

Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons

Rosli, Nurlina, Christie, Michelle, Moyle, Peter M. and Toth, Istvan (2015). Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons. Bioorganic & Medicinal Chemistry, 23 (10), 2470-2479. doi: 10.1016/j.bmc.2015.03.058

Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons

2014

Journal Article

Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity

Zaman, Mehfuz, Chandrudu, Saranya, Giddam, Ashwini K., Reiman, Jennifer, Skwarczynski, Mariusz, McPhun, Virginia, Moyle, Peter M., Batzloff, Michael R., Good, Michael F. and Toth, Istvan (2014). Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity. Nanomedicine, 9 (17), 2613-2624. doi: 10.2217/NNM.14.190

Group A Streptococcal vaccine candidate: contribution of epitope to size, antigen presenting cell interaction and immunogenicity

2014

Journal Article

The contribution of non-human primate models to the development of human vaccines

Rivera-Hernandez, Tania, Carnathan, Diane G., Moyle, Peter M., Toth, Istvan, West, Nicholas P., Young, Paul L., Silvestri, Guido and Walker, Mark J. (2014). The contribution of non-human primate models to the development of human vaccines. Discovery Medicine, 18 (101), 313-322.

The contribution of non-human primate models to the development of human vaccines

2014

Journal Article

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

Ahmad Fuaad, Abdullah A. H., Jia, Zhongfan, Hartas, Jon, Ziora, Zyta M., Lin, I-Chun, Moyle, Peter M., Batzloff, Michael R., Good, Michael F., Monteiro, Michael J., Skwarczynski, Mariusz and Toth, Istvan (2014). Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine. Nanomedicine, 9 (1), 35-43. doi: 10.2217/NNM.13.7

Polymer–peptide hybrids as a highly immunogenic single-dose nanovaccine

2013

Journal Article

Synthesis and characterization of luteinizing hormone-releasing hormone (LHRH)-functionalized mini-dendrimers

Rafiee, Amirreza, Mansfeld, Friederike M., Moyle, Peter M. and Toth, Istvan (2013). Synthesis and characterization of luteinizing hormone-releasing hormone (LHRH)-functionalized mini-dendrimers. International Journal of Chemistry, 3 (1), 51-57. doi: 10.4236/ijoc.2013.31006

Synthesis and characterization of luteinizing hormone-releasing hormone (LHRH)-functionalized mini-dendrimers

2011

Journal Article

Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products

Simerska, Pavla, Moyle, Peter M. and Toth, Istvan (2011). Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products. Medicinal Research Reviews, 31 (4), 520-547. doi: 10.1002/med.20191

Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products

2009

Journal Article

Oral vaccine delivery - New strategies and technologies

Simerska, Pavla, Moyle, Peter M., Olive, Colleen and Toth, Istvan (2009). Oral vaccine delivery - New strategies and technologies. Current Drug Delivery, 6 (4), 347-358. doi: 10.2174/156720109789000537

Oral vaccine delivery - New strategies and technologies

2008

Journal Article

Development of a liposaccharide-based delivery system and its application to the design of Group A streptococcal vaccines

Simerska, Pavla, Abdel-Aal, Abu-Baker M., Fujita, Yoshio, Moyle, Peter M., McGeary, Ross P., Batzloff, Michael R., Olive, Colleen, Good, Michael F. and Toth, Istvan (2008). Development of a liposaccharide-based delivery system and its application to the design of Group A streptococcal vaccines. Journal of Medicinal Chemistry, 51 (5), 1447-1452. doi: 10.1021/jm701410p

Development of a liposaccharide-based delivery system and its application to the design of Group A streptococcal vaccines

2008

Journal Article

Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group A streptococcal vaccine candidates

Abdel-Aal, Abu-Baker M., Batzloff, Michael R., Fujita, Yoshio, Barozzi, Nadia, Faria, Andres, Simerska, Pavla, Moyle, Peter M., Good, Michael F. and Toth, Istvan (2008). Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group A streptococcal vaccine candidates. Journal of Medicinal Chemistry, 51 (1), 167-172. doi: 10.1021/jm701091d

Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group A streptococcal vaccine candidates

2008

Journal Article

Self-adjuvanting lipopeptide vaccines

Moyle, P.M. and Toth, I. (2008). Self-adjuvanting lipopeptide vaccines. Current Medicinal Chemistry, 15 (5), 506-516. doi: 10.2174/092986708783503249

Self-adjuvanting lipopeptide vaccines

2007

Journal Article

Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide System

Olive, C., Moyle, P. and Toth, I. (2007). Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide System. Current Medicinal Chemistry, 14 (28), 2976-2988. doi: 10.2174/092986707782794069

Towards the Development of a Broadly Protective Group A Streptococcal Vaccine Based on the Lipid-Core Peptide System

2007

Journal Article

A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines

Moyle, PM, Hari, Y, Huang, N, Olive, C, Good, MF and Toth, I (2007). A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines. Tetrahedron Letters, 48 (29), 4965-4967. doi: 10.1016/j.tetlet.2007.05.129

A technique for the synthesis of highly-pure, mono-epitopic, multi-valent lipid core peptide vaccines

2007

Journal Article

Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines

Moyle, Peter M., Olive, Colleen, Ho, Mei-Fong, Pandey, Manisha, Dyer, Joanne, Suhrbier, Andreas, Fujita, Yoshio and Toth, Istvan (2007). Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. Journal of Medicinal Chemistry, 50 (19), 4721-4727. doi: 10.1021/jm070287b

Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines

2006

Journal Article

Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation

Moyle, P. M., Olive, C., Ho, M. F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation. Journal of Organic Chemistry, 71 (18), 6846-6850. doi: 10.1021/jo060960p

Method for the Synthesis of Multi-Epitopic Streptococcus pyogenes Lipopeptide Vaccines Using Native Chemical Ligation

2006

Journal Article

The lipid core peptide system in vaccine delivery

Toth, Istvan, Moyle, Peter, Karpati, Levente, Horvath, Aniko, Olive, Colleen and Good, Michael (2006). The lipid core peptide system in vaccine delivery. International Congress Series, 1289, 307-310. doi: 10.1016/j.ics.2005.11.057

The lipid core peptide system in vaccine delivery

2006

Journal Article

Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine

Moyle, P. M., Olive, C., Ho, M.-F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine. International Congress Series, 1289, 324-328. doi: 10.1016/j.ics.2005.11.084

Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine

2006

Journal Article

Method for the synthesis of highly pure vaccines using the lipid core peptide system

Moyle, P. M., Olive, C., Good, M. F. and Toth, I. (2006). Method for the synthesis of highly pure vaccines using the lipid core peptide system. Journal of Peptide Science, 12 (12), 800-807. doi: 10.1002/psc.815

Method for the synthesis of highly pure vaccines using the lipid core peptide system

2006

Journal Article

Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A Streptococcal vaccine, and subsequent immunological evaluation

Moyle, P. M., Olive, C., Ho, M. F., Good, M. F. and Toth, I. (2006). Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A Streptococcal vaccine, and subsequent immunological evaluation. Journal of Medicinal Chemistry, 49 (21), 6364-6370. doi: 10.1021/jm060475m

Synthesis of a highly pure lipid core peptide based self-adjuvanting triepitopic group A Streptococcal vaccine, and subsequent immunological evaluation

2004

Journal Article

Mucosal immunization: Adjuvants and delivery systems

Moyle, P.M., McGeary, R. P., Blanchfield, J. T. and Toth, I. (2004). Mucosal immunization: Adjuvants and delivery systems. Current Drug Delivery, 1 (4), 385-396. doi: 10.2174/1567201043334588

Mucosal immunization: Adjuvants and delivery systems