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2021

Journal Article

The value of open-source clinical science in pandemic response: lessons from ISARIC

Abbas, Ali, Abdukahil, Sheryl Ann, Abdulkadir, Nurul Najmee, Abe, Ryuzo, Abel, Laurent, Absil, Lara, Acharya, Subhash, Acker, Andrew, Adachi, Shingo, Adam, Elisabeth, Adrião, Diana, Ageel, Saleh Al, Ahmed, Shakeel, Ain, Quratul, Ainscough, Kate, Aisa, Tharwat, Ait Hssain, Ali, Ait Tamlihat, Younes, Akimoto, Takako, Akmal, Ernita, Al Qasim, Eman, Alalqam, Razi, Alam, Tanvir, Al-dabbous, Tala, Alegesan, Senthilkumar, Alegre, Cynthia, Alessi, Marta, Alex, Beatrice, Alexandre, Kévin ... ISARIC Clinical Characterisation Group (2021). The value of open-source clinical science in pandemic response: lessons from ISARIC. The Lancet Infectious Diseases, 21 (12), 1623-1624. doi: 10.1016/S1473-3099(21)00565-X

The value of open-source clinical science in pandemic response: lessons from ISARIC

2021

Journal Article

Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort

ISARIC Clinical Characterisation Group, Hall, Matthew D., Baruch, Joaquín, Carson, Gail, Citarella, Barbara Wanjiru, Dagens, Andrew, Dankwa, Emmanuelle A., Donnelly, Christl A., Dunning, Jake, Escher, Martina, Kartsonaki, Christiana, Merson, Laura, Pritchard, Mark, Wei, Jia, Horby, Peter W., Rojek, Amanda, Olliaro, Piero L., Li Bassi, Gianluigi, Shrapnel, Sally, Suen, Jacky and Forsyth, Simon J. (2021). Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort. eLife, 10 e70970, 1-30. doi: 10.7554/elife.70970

Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort

2021

Journal Article

Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study

Li Bassi, Gianluigi, Suen, Jacky Y., White, Nicole, Dalton, Heidi J., Fanning, Jonathon, Corley, Amanda, Shrapnel, Sally, Hinton, Samuel, Forsyth, Simon, Parsons, Rex, Laffey, John G., Fan, Eddy, Bartlett, Robert, Brodie, Daniel, Burrell, Aidan, Chiumello, Davide, Elhazmi, Alyaa, Grasselli, Giacomo, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Marwali, Eva, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Panigada, Mauro, Pelosi, Paolo, Torres, Antoni, Ng, Pauline Yeung ... Obonyo, Nchafatso (2021). Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study. Critical Care Explorations, 3 (11) e0567, e0567. doi: 10.1097/cce.0000000000000567

Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study

2021

Journal Article

Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model

Walweel, K., Boon, A. C., See Hoe, L. E., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Colombo, S. M., Bartnikowski, N. J., Bouquet, M., Wells, M. A., Black, D. M., Pimenta, L. P., Stevenson, A. K., Bisht, K., Skeggs, K., Marshall, L., Prabhu, A., James, L. N., Platts, D. G., Macdonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2021). Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model. Biomedical Journal, 45 (5), 776-787. doi: 10.1016/j.bj.2021.10.007

Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model

2021

Journal Article

An innovative ovine model of severe cardiopulmonary failure supported by veno-arterial extracorporeal membrane oxygenation

Heinsar, Silver, Jung, Jae-Seung, Colombo, Sebastiano Maria, Rozencwajg, Sacha, Wildi, Karin, Sato, Kei, Ainola, Carmen, Wang, Xiaomeng, Abbate, Gabriella, Sato, Noriko, Dyer, Wayne Bruce, Livingstone, Samantha Annie, Pimenta, Leticia Pretti, Bartnikowski, Nicole, Bouquet, Mahe Jeannine Patricia, Passmore, Margaret, Vidal, Bruno, Palmieri, Chiara, Reid, Janice D., Haqqani, Haris M., McGuire, Daniel, Wilson, Emily Susan, Rätsep, Indrek, Lorusso, Roberto, Suen, Jacky Y., Li Bassi, Gianluigi and Fraser, John F. (2021). An innovative ovine model of severe cardiopulmonary failure supported by veno-arterial extracorporeal membrane oxygenation. Scientific Reports, 11 (1) 20458, 1-11. doi: 10.1038/s41598-021-00087-y

An innovative ovine model of severe cardiopulmonary failure supported by veno-arterial extracorporeal membrane oxygenation

2021

Journal Article

Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study

Millar, Jonathan E., Wildi, Karin, Bartnikowski, Nicole, Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Ki, Katrina K., See Hoe, Louise E., Obonyo, Nchafatso G., Neyton, Lucile, Pedersen, Sanne, Rozencwajg, Sacha, Baillie, J. Kenneth, Li Bassi, Gianluigi, Suen, Jacky Y., McAuley, Daniel F. and Fraser, John F. (2021). Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study. Physiological Reports, 9 (19) e15048, e15048. doi: 10.14814/phy2.15048

Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study

2021

Journal Article

Design and rationale of a prospective international follow-up study on intensive care survivors of COVID-19: The long-term impact in intensive care survivors of coronavirus disease-19-AFTERCOR

Wildi, Karin, Li Bassi, Gianluigi, Barnett, Adrian, Panigada, Mauro, Colombo, Sebastiano M., Bandera, Alessandra, Muscatello, Antonio, McNicholas, Bairbre, Laffey, John G., Battaglini, Denise, Robba, Chiara, Torres, Antoni, Motos, Ana, Luna, Carlos M., Rainieri, Fernando, Hodgson, Carol, Burrell, Aidan J. C., Buscher, Hergen, Dalton, Heidi, Cho, Sung-Min, Choi, Huimahn Alex, Thomson, David, Suen, Jacky and Fraser, John F. (2021). Design and rationale of a prospective international follow-up study on intensive care survivors of COVID-19: The long-term impact in intensive care survivors of coronavirus disease-19-AFTERCOR. Frontiers in Medicine, 8 738086, 738086. doi: 10.3389/fmed.2021.738086

Design and rationale of a prospective international follow-up study on intensive care survivors of COVID-19: The long-term impact in intensive care survivors of coronavirus disease-19-AFTERCOR

2021

Journal Article

Anti-thrombogenic surface coatings for extracorporeal membrane oxygenation: a narrative review

Zhang, Meili, Pauls, Jo P., Bartnikowski, Nicole, Haymet, Andrew B., Chan, Chris H. H., Suen, Jacky Y., Schneider, Bailey, Ki, Katrina K., Whittaker, Andrew K., Dargusch, Matthew S. and Fraser, John F. (2021). Anti-thrombogenic surface coatings for extracorporeal membrane oxygenation: a narrative review. ACS Biomaterials Science and Engineering, 7 (9), 4402-4419. doi: 10.1021/acsbiomaterials.1c00758

Anti-thrombogenic surface coatings for extracorporeal membrane oxygenation: a narrative review

2021

Journal Article

Coagulation dysfunction in acute respiratory distress syndrome and its potential impact in inflammatory subphenotypes

Livingstone, Samantha A., Wildi, Karin S., Dalton, Heidi J., Usman, Asad, Ki, Katrina K., Passmore, Margaret R., Li Bassi, Gianluigi, Suen, Jacky Y. and Fraser, John F. (2021). Coagulation dysfunction in acute respiratory distress syndrome and its potential impact in inflammatory subphenotypes. Frontiers in Medicine, 8 723217, 723217. doi: 10.3389/fmed.2021.723217

Coagulation dysfunction in acute respiratory distress syndrome and its potential impact in inflammatory subphenotypes

2021

Journal Article

Neurological manifestations of coronavirus disease 2019: a comprehensive review and meta-analysis of the first 6 months of pandemic reporting

Huth, Samuel F., Cho, Sung-Min, Robba, Chiara, Highton, David, Battaglini, Denise, Bellapart, Judith, Suen, Jacky Y., Li Bassi, Gianluigi, Taccone, Fabio Silvio, Arora, Rakesh C., Whitman, Glenn, Fraser, John F. and Fanning, Jonathon P. (2021). Neurological manifestations of coronavirus disease 2019: a comprehensive review and meta-analysis of the first 6 months of pandemic reporting. Frontiers in Neurology, 12 664599, 664599. doi: 10.3389/fneur.2021.664599

Neurological manifestations of coronavirus disease 2019: a comprehensive review and meta-analysis of the first 6 months of pandemic reporting

2021

Journal Article

Ischemic and hemorrhagic stroke among critically ill patients with coronavirus disease 2019: an International Multicenter Coronavirus Disease 2019 Critical Care Consortium study

Cho, Sung-Min, Premraj, Lavienraj, Fanning, Jonathon, Huth, Samuel, Barnett, Adrian, Whitman, Glenn, Arora, Rakesh C., Battaglini, Denise, Porto, Diego Bastos, Choi, HuiMahn, Suen, Jacky, Bassi, Gianluigi Li, Fraser, John F., Robba, Chiara and Griffee, Matthew (2021). Ischemic and hemorrhagic stroke among critically ill patients with coronavirus disease 2019: an International Multicenter Coronavirus Disease 2019 Critical Care Consortium study. Critical Care Medicine, 49 (12), E1223-E1233. doi: 10.1097/CCM.0000000000005209

Ischemic and hemorrhagic stroke among critically ill patients with coronavirus disease 2019: an International Multicenter Coronavirus Disease 2019 Critical Care Consortium study

2021

Journal Article

Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death

Wells, Matthew A., See Hoe, Louise E., Molenaar, Peter, Pedersen, Sanne, Obonyo, Nchafatso G., McDonald, Charles I., Mo, Weilan, Bouquet, Mahè, Hyslop, Kieran, Passmore, Margaret R., Bartnikowski, Nicole, Suen, Jacky Y., Peart, Jason N., McGiffin, David C., Fraser, John F. and on behalf of the Dead Heart Project (2021). Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death. Pharmacological Research, 169 105631, 1-12. doi: 10.1016/j.phrs.2021.105631

Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death

2021

Journal Article

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

ISARIC Clinical Characterisation Group, Li Bassi, Gianluigi, Scarsbrook, Joshua, Shrapnel, Sally, Suen, Jacky and Forsyth, Simon J. (2021). COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study. Infection, 49 (5), 889-905. doi: 10.1007/s15010-021-01599-5

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

2021

Journal Article

Ethical factors determining ECMO allocation during the COVID-19 pandemic

Dao, Bernadine, Savulescu, Julian, Suen, Jacky Y., Fraser, John F. and Wilkinson, Dominic J. C. (2021). Ethical factors determining ECMO allocation during the COVID-19 pandemic. BMC Medical Ethics, 22 (1) 70, 1-12. doi: 10.1186/s12910-021-00638-y

Ethical factors determining ECMO allocation during the COVID-19 pandemic

2021

Journal Article

Extracorporeal membrane oxygenation-induced hemolysis: an in vitro study to appraise causative factors

Chan, Chris Hoi Houng, Ki, Katrina K., Zhang, Meili, Asnicar, Cooper, Cho, Hwajin, Ainola, Carmen, Bouquet, Mahe, Heinsar, Silver, Pauls, Jo Philipp, Li Bassi, Gianluigi, Suen, Jacky and Fraser, John F. (2021). Extracorporeal membrane oxygenation-induced hemolysis: an in vitro study to appraise causative factors. Membranes, 11 (5) 313, 313. doi: 10.3390/membranes11050313

Extracorporeal membrane oxygenation-induced hemolysis: an in vitro study to appraise causative factors

2021

Journal Article

Studying the Endothelial Glycocalyx : What Is Missing?

Haymet, Andrew B., Bartnikowski, Nicole, Wood, Emily S., Vallely, Michael P., McBride, Angela, Yacoub, Sophie, Biering, Scott B., Harris, Eva, Suen, Jacky Y. and Fraser, John F. (2021). Studying the Endothelial Glycocalyx : What Is Missing?. Frontiers in Cardiovascular Medicine, 8 647086, 1-13. doi: 10.3389/fcvm.2021.647086

Studying the Endothelial Glycocalyx : What Is Missing?

2021

Journal Article

Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines

Morais, Christudas, Rajandram, Retnagowri, Blakeney, Jade S., Iyer, Abishek, Suen, Jacky Y., Johnson, David W., Gobe, Glenda C., Fairlie, David P. and Vesey, David A. (2021). Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines. PLoS One, 16 (3) e0248983, e0248983. doi: 10.1371/journal.pone.0248983

Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines

2021

Journal Article

Peritransplant cardio-metabolic and mitochondrial function: the missing piece in donor heart dysfunction and graft failure

Wells, Matthew A., See Hoe, Louise E., Heather, Lisa C., Molenaar, Peter, Suen, Jacky Y., Peart, Jason, McGiffin, David and Fraser, John F. (2021). Peritransplant cardio-metabolic and mitochondrial function: the missing piece in donor heart dysfunction and graft failure. Transplantation, 105 (3), 496-508. doi: 10.1097/tp.0000000000003368

Peritransplant cardio-metabolic and mitochondrial function: the missing piece in donor heart dysfunction and graft failure

2021

Journal Article

Correction to: the discovery of biological subphenotypes in ARDS: a novel approach to targeted medicine?

Wildi, Karin, Livingstone, Samantha, Palmieri, Chiara, LiBassi, Gianluigi, Suen, Jacky and Fraser, John (2021). Correction to: the discovery of biological subphenotypes in ARDS: a novel approach to targeted medicine?. Journal of Intensive Care, 9 (1) 22, 22. doi: 10.1186/s40560-021-00534-y

Correction to: the discovery of biological subphenotypes in ARDS: a novel approach to targeted medicine?

2021

Journal Article

Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: a propensity score analysis

Li Bassi, Gianluigi, Gibbons, Kristen, Suen, Jacky Y., Dalton, Heidi J., White, Nicole, Corley, Amanda, Hinton, Samuel, Forsyth, Simon, Laffey, John G., Brodie, Daniel, Burrell, Aidan, Fan, Eddy, Bartlett, Robert, Torres, Antoni, Chiumello, Davide, Elhazmi, Alyaa, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Murthy, Srinivas, Nichol, Alistair, Ng, Pauline Yeung, Ogino, Mark, Panigada, Mauro, Pesenti, Antonio and Fraser, John F. (2021). Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: a propensity score analysis. SSRN Electronic Journal. doi: 10.2139/ssrn.3773555

Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: a propensity score analysis