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2016 Journal Article Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosisFogarty, Matthew J., Klenowski, Paul M., Lee, John D., Drieberg-Thompson, Joy R., Bartlett, Selena E., Ngo, Shyuan T., Hilliard, Massimo A., Bellingham, Mark C. and Noakes, Peter G. (2016). Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosis. Scientific Reports, 6 (1) 37968, 37968. doi: 10.1038/srep37968 |
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2016 Journal Article The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: in vitro and in vivo studiesCarrasco-Pozo, Catalina, Tan, Kah Ni, Reyes-Farias, Marjorie, De La Jara, Nicole, Ngo, Shyuan Thieu, Garcia-Diaz, Diego Fernando, Llanos, Paola, Cires, Maria Jose and Borges, Karin (2016). The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: in vitro and in vivo studies. Redox Biology, 9, 229-243. doi: 10.1016/j.redox.2016.08.007 |
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2016 Journal Article Altered metabolic homeostasis in amyotrophic lateral sclerosis: mechanisms of energy imbalance and contribution to disease progressionIoannides, Z. A., Ngo, S. T., Henderson, R. D., McCombe, P. A. and Steyn, F. J. (2016). Altered metabolic homeostasis in amyotrophic lateral sclerosis: mechanisms of energy imbalance and contribution to disease progression. Neurodegenerative Diseases, 15 (5-6), 382-397. doi: 10.1159/000446502 |
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2016 Journal Article Triheptanoin protects motor neurons and delays the onset of motor symptoms in a mouse model of amyotrophic lateral sclerosisTefera, Tesfaye W., Wong, Yide, Barkl-Luke, Mallory E., Ngo, Shyuan T., Thomas, Nicola K., McDonald, Tanya S. and Borges, Karin (2016). Triheptanoin protects motor neurons and delays the onset of motor symptoms in a mouse model of amyotrophic lateral sclerosis. Plos One, 11 (8) e0161816, e0161816. doi: 10.1371/journal.pone.0161816 |
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2016 Journal Article Development of a high-throughput method for real-time assessment of cellular metabolism in intact long skeletal muscle fibre bundlesLi, Rui, Steyn, Frederik J., Stout, Michael B., Lee, Kevin, Cully, Tanya R., Calderon, Juan C. and Ngo, Shuyan T. (2016). Development of a high-throughput method for real-time assessment of cellular metabolism in intact long skeletal muscle fibre bundles. The Journal of Physiology, 594 (24), 7197-7213. doi: 10.1113/JP272988 |
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2015 Journal Article Effect of deletion of ghrelin-o-acyltransferase on the pulsatile release of growth hormone in miceXie, T. Y., Ngo, S. T., Veldhuis, J. D., Jeffery, P. L., Chopin, L. K., Tschop, M., Waters, M. J., Tolle, V., Epelbaum, J., Chen, C. and Steyn, F. J. (2015). Effect of deletion of ghrelin-o-acyltransferase on the pulsatile release of growth hormone in mice. Journal of Neuroendocrinology, 27 (12), 872-886. doi: 10.1111/jne.12327 |
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2015 Journal Article Altered expression of metabolic proteins and adipokines in patients with amyotrophic lateral sclerosisNgo, S. T., Steyn, F. J., Huang, L., Mantovani, S., Pfluger, C. M. M., Woodruff, T. M., O'Sullivan, J. D., Henderson, R. D. and McCombe, P. A. (2015). Altered expression of metabolic proteins and adipokines in patients with amyotrophic lateral sclerosis. Journal of the Neurological Sciences, 357 (1-2), 22-27. doi: 10.1016/j.jns.2015.06.053 |
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2015 Journal Article The interplay between metabolic homeostasis and neurodegeneration: insights into the neurometabolic nature of amyotrophic lateral sclerosisNgo, S. T. and Steyn, F. J. (2015). The interplay between metabolic homeostasis and neurodegeneration: insights into the neurometabolic nature of amyotrophic lateral sclerosis. Cell Regeneration, 4 (5) 5, 1-14. doi: 10.1186/s13619-015-0019-6 |
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2015 Journal Article A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosisPalamiuc, Lavinia, Schlagowski, Anna, Ngo, Shyuan T., Vernay, Aurelia, Dirrig-Grosch, Sylvie, Henriques, Alexandre, Boutillier, Anne-Laurence, Zoll, Joffrey, Echaniz-Laguna, Andoni, Loeffler, Jean-Philippe and René, Frédérique (2015). A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis. EMBO Molecular Medicine, 7 (5), 526-546. doi: 10.15252/emmm.201404433 |
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2014 Journal Article Gender differences in autoimmune diseaseNgo, S. T., Steyn, F. J. and McCombe, P. A. (2014). Gender differences in autoimmune disease. Frontiers in Neuroendocrinology, 35 (3), 347-369. doi: 10.1016/j.yfrne.2014.04.004 |
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2014 Journal Article Body mass index and dietary intervention: Implications for prognosis of amyotrophic lateral sclerosisNgo, S.T., Steyn, F.J. and McCombe, P.A. (2014). Body mass index and dietary intervention: Implications for prognosis of amyotrophic lateral sclerosis. Journal of the Neurological Sciences, 340 (1-2), 5-12. doi: 10.1016/j.jns.2014.02.035 |
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2013 Journal Article Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis miceSteyn, F. J., Lee, Kevin, Fogarty, M. J., Veldhuis, J. D., McCombe, P. A,, Bellingham, M. C., Ngo, S. T. and Chen, C (2013). Growth hormone secretion is correlated with neuromuscular innervation rather than motor neuron number in early-symptomatic male amyotrophic lateral sclerosis mice. Endocrinology, 154 (12), 4695-4706. doi: 10.1210/en.2013-1570 |
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2013 Journal Article Increased adiposity and insulin correlates with the progressive suppression of pulsatile GH secretion during weight gainSteyn, F. J., Xie, T. Y., Huang, L., Ngo, S. T., Veldhuis, J. D., Waters, M. J. and Chen, C. (2013). Increased adiposity and insulin correlates with the progressive suppression of pulsatile GH secretion during weight gain. Journal of Endocrinology, 218 (2), 233-244. doi: 10.1530/JOE-13-0084 |
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2012 Journal Article The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) miceNgo, S. T., Baumann, F., Ridall, P. G., Pettitt, A. N., Henderson, R. D., Bellingham, M. C. and McCombe, P. A. (2012). The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice. Clinical Neurophysiology, 123 (10), 2080-2091. doi: 10.1016/j.clinph.2012.01.028 |
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2012 Journal Article The decline in pulsatile GH secretion throughout early adulthood in mice is exacerbated by dietary-induced weight gainHuang, L., Steyn, F. J., Tan, H. Y., Xie, T. Y., Veldhuis, J. D., Ngo, S. T. and Chen, C. (2012). The decline in pulsatile GH secretion throughout early adulthood in mice is exacerbated by dietary-induced weight gain. Endocrinology, 153 (9), 4380-4388. doi: 10.1210/en.2012-1178 |
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2012 Journal Article Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylationNgo, Shyuan T., Cole, Rebecca N., Sunn, Nana, Phillips, William D. and Noakes, Peter G. (2012). Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation. Journal of Cell Science, 125 (6), 1531-1543. doi: 10.1242/jcs.095109 |
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2012 Journal Article Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosisSteyn, F. J., Ngo, S. T, Lee, J. D., Leong, J. W., Buckley, A. J., Veldhuis, J. D., McCombe, P. A., Chen, C. and Bellingham, M. C. (2012). Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis. Endocrinology, 153 (8), 3735-3746. doi: 10.1210/en.2011-2171 |
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2011 Journal Article Development of a method for the determination of pulsatile growth hormone secretion in miceSteyn, F. J., Huang, L., Ngo, S. T., Leong, J. W., Tan, H. Y., Xie, T. Y., Parlow, A. F., Veldhuis, J. D., Waters, M. J. and Chen, C. (2011). Development of a method for the determination of pulsatile growth hormone secretion in mice. Endocrinology, 152 (8), 3165-3171. doi: 10.1210/en.2011-0253 |
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2011 Journal Article Muscle Specific Kinase: Organiser of synaptic membrane domainsGhazanfari, Nazanin, Fernandez, Kristine J., Murata, Yui, Morsch, Marco, Ngo, Shyuan T., Reddel, Stephen W., Noakes, Peter G. and Phillips, William D. (2011). Muscle Specific Kinase: Organiser of synaptic membrane domains. The International Journal of Biochemistry and Cell Biology, 43 (3), 295-298. doi: 10.1016/j.biocel.2010.10.008 |
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2010 Journal Article Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in miceCole, R. N., Ghazanfari, N., Ngo, S. T., Gervasio, O. L., Reddel, S. W. and Phillips, W. D. (2010). Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice. Journal of Physiology, 588 (17), 3217-3229. doi: 10.1113/jphysiol.2010.190298 |
