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2026 Journal Article Blood lactate as a prognostic biomarker for survival and weight loss in amyotrophic lateral sclerosis: an exploratory–validation studyNakamura, Ryutaro, Steyn, Frederik J., Kobashi, Shuhei, Ogawa, Nobuhiro, Kitamura, Akihiro, Yamakawa, Isamu, Henderson, Robert D., Ngo, Shyuan T. and Urushitani, Makoto (2026). Blood lactate as a prognostic biomarker for survival and weight loss in amyotrophic lateral sclerosis: an exploratory–validation study. Annals of Neurology, 99 (6), 1526-1535. doi: 10.1002/ana.78184 |
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2026 Journal Article Multimodal ultra-high-field MRI, clinical, cognitive, and genetic profiles across the ALS–FTD spectrumShaw, Thomas B., Al Najjar, Aiman, Barth, Markus, Bollmann, Steffen, Bourgeat, Pierrick, Chang, Jeryn, Dempsey-Jones, Harriet, Fazlollahi, Amir, Fripp, Jurgen, Garden, Natalie, Guo, Christine C., Henderson, Robert D., Kuan, Elaine, Lv, Jinglei, McCombe, Pamela A., Narayanan, Aswin, Ngo, Shyuan T., Nguyen, Vinh, O’Brien, Kieran, Robinson, Gail, Robinson, Simon, Salvado, Olivier, Stewart, Ashley, Steyn, Frederik J. and Bollmann, Saskia (2026). Multimodal ultra-high-field MRI, clinical, cognitive, and genetic profiles across the ALS–FTD spectrum. Scientific Data. doi: 10.1038/s41597-026-07461-3 |
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2026 Journal Article Gut microbiota and ALS: cause, consequence or correlation? - a systematic reviewChakraborty, Debarghya Kumar, Roy, Triparna, Ngo, Shyuan Thieu, Al-Chalabi, Ammar and Al Khleifat, Ahmad (2026). Gut microbiota and ALS: cause, consequence or correlation? - a systematic review. Frontiers in Neuroscience, 20 1774417. doi: 10.3389/fnins.2026.1774417 |
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2026 Journal Article White matter changes in reward circuits of amyotrophic lateral sclerosis: a fixel-based study of appetite lossChang, Jeryn, Lipscombe, Harry, Lv, Jinglei, McCombe, Pamela A., Henderson, Robert D., Ngo, Shyuan T., Steyn, Frederik J. and Shaw, Thomas B. (2026). White matter changes in reward circuits of amyotrophic lateral sclerosis: a fixel-based study of appetite loss. BMC Medicine, 24 (1) 295, 1. doi: 10.1186/s12916-026-04763-6 |
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2026 Journal Article Review of the pathology of muscle in amyotrophic lateral sclerosisKatz, Matthew, Robertson, Thomas, Ngo, Shyuan T., Yarlagadda, Sai, Henderson, Robert D., McCombe, Pamela A. and Noakes, Peter G. (2026). Review of the pathology of muscle in amyotrophic lateral sclerosis. International Journal of Molecular Sciences, 27 (6) 2802, 1-33. doi: 10.3390/ijms27062802 |
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2026 Journal Article Treating age-related loss of muscle mass and function: Where should we be focusing?Ham, Daniel J., Fry, Christopher S., Ruparelia, Avnika Ashok, Ngo, Shyuan T. and Lamon, Severine (2026). Treating age-related loss of muscle mass and function: Where should we be focusing?. Journal of Physiology-London JP289838. doi: 10.1113/JP289838 |
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2026 Journal Article Systemic immune-metabolic interactions in patients with amyotrophic lateral sclerosis: correlations of plasma cytokines with metabolic statusHowe, Stephanie L., Holdom, Cory J., McCombe, Pamela A., Henderson, Robert D., Steyn, Frederik J. and Ngo, Shyuan T. (2026). Systemic immune-metabolic interactions in patients with amyotrophic lateral sclerosis: correlations of plasma cytokines with metabolic status. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 1-11. doi: 10.1080/21678421.2026.2627902 |
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2026 Journal Article Examining the impact and role of lipid classes on the risk of amyotrophic lateral sclerosis (ALS) onset: a systematic review and GRADE analysis of the evidenceSewell-Green, Amber R., Kuiper, Merle, Holdom, Cory J., Beelen, Anita, Ngo, Shyuan T., Steyn, Frederik J. and Matthews-Rensch, Kylie L. (2026). Examining the impact and role of lipid classes on the risk of amyotrophic lateral sclerosis (ALS) onset: a systematic review and GRADE analysis of the evidence. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 27 (3-4), 370-382. doi: 10.1080/21678421.2025.2574685 |
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2026 Journal Article Lower-limb biomechanics in motor neuron disease: a joint-level perspective of gait disruptionHoldom, Cory J., Williamson, James L., O’Reilly, Georgia, Henderson, Robert D., Neville, Sally, Ngo, Shyuan T., Dick, Taylor J. M. and Steyn, Frederik J. (2026). Lower-limb biomechanics in motor neuron disease: a joint-level perspective of gait disruption. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 27 (1-2), 44-54. doi: 10.1080/21678421.2025.2523945 |
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2025 Journal Article BLOC1S1 depletion via splice-switching oligonucleotides improves mitochondrial respiration and rescues ALS phenotypesHor, Jin-Hui, Ow, Jin Rong, Ng, Winanto, Ramasamy, Boominathan, Tabaglio, Tommaso, Lim, Kimberly Ngee Hui, Bin Muzakar, Muhammad Ikhsan, Lim, Valerie Jing Wen, Gurrampati, Rajasekhar Reddy, Rajarethinam, Ravisankar, Ngo, Shyuan T., Ramadass, Venkataramanan, Lakshmanan, Manikandan, Ling, Shuo-Chien, Wee, Keng Boon and Ng, Shi-Yan (2025). BLOC1S1 depletion via splice-switching oligonucleotides improves mitochondrial respiration and rescues ALS phenotypes. Molecular Therapy, 34 (3), 1672-1683. doi: 10.1016/j.ymthe.2025.12.026 |
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2025 Conference Publication NaV-igating motor neurodegeneration: voltage-gated sodium channels are major drivers of hyperexcitability-induced neuropathology and therapeutic targets in amyotrophic lateral sclerosisKotapati, Charan, Kanhjan, Refik, Jiang, Leanne, Ngo, Shyuan and Cardoso, Fernanda C (2025). NaV-igating motor neurodegeneration: voltage-gated sodium channels are major drivers of hyperexcitability-induced neuropathology and therapeutic targets in amyotrophic lateral sclerosis. Cellular and Molecular Advances in Neurodegeneration, Hobart, TAS, Australia, 4-5 December 2025. |
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2025 Journal Article Long-term fixation impact on archived human nervous tissues for sequencing-based transcriptomicsHowe, Stephanie, McCann, Heather, Xiong, Zherui, Nguyen, Quan, Steyn, Frederik J., Ngo, Shyuan T. and Chang, Jeryn (2025). Long-term fixation impact on archived human nervous tissues for sequencing-based transcriptomics. Brain Communications, 7 (6) fcaf428, fcaf428. doi: 10.1093/braincomms/fcaf428 |
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2025 Journal Article Epigenetic profiles of tissue informative CpGs inform ALS disease status and progressionCaggiano, Christa, Morselli, Marco, Qian, Xiaoyu, Celona, Barbara, Thompson, Michael J., Wani, Shivangi, Tosevska, Anela, Taraszka, Kodi, Heuer, Galen, Ngo, Shyuan T., Steyn, Frederick J., Nestor, Peter J., Wallace, Leanne, Mccombe, Pamela, Heggie, Susan, Thorpe, Kathryn, Mcelligott, Caitlin, English, Gemyka, Henders, Anjali, Henderson, Robert, Lomen-Hoerth, Catherine, Wray, Naomi R., Mcrae, Allan F., Pellegrini, Matteo, Garton, Fleur C. and Zaitlen, Noah (2025). Epigenetic profiles of tissue informative CpGs inform ALS disease status and progression. Genome Medicine, 17 (1) 115, 1-20. doi: 10.1186/s13073-025-01542-5 |
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2025 Conference Publication The impact of blood lipid classes on risk of amyotrophic lateral sclerosis: a systematic review and grade analysisSewell-Green, A., Kuiper, M., Beelan, A., Steyn, F., Ngo, S. and Matthews-Rensch, K. (2025). The impact of blood lipid classes on risk of amyotrophic lateral sclerosis: a systematic review and grade analysis. Unknown, Unknown, Unknown. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.clnesp.2025.07.267 |
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2025 Conference Publication Evaluating the impact of weight loss and accuracy of energy equations in Australians with amyotrophic lateral sclerosisSewell-Green, A., Capstick, R., Matthews-Rensch, K., Ngo, S., Henderson, R. and Steyn, F. (2025). Evaluating the impact of weight loss and accuracy of energy equations in Australians with amyotrophic lateral sclerosis. Unknown, Unknown, Unknown. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.clnesp.2025.07.788 |
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2025 Conference Publication In vivo axonal transport of mitochondria and signalling endosomes is impaired in fast α-μοτοr neurons in MND miceTosolini, Andrew P., Ngo, Shyuan T. and Schiavo, Giampietro (2025). In vivo axonal transport of mitochondria and signalling endosomes is impaired in fast α-μοτοr neurons in MND mice. PACTALS Congress 2025, Melbourne, VIC, Australia, 7-9 September 2025. |
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2025 Journal Article Segmentation of the human tongue musculature using MRI: Field guide and validation in motor neuron diseaseShaw, Thomas B., Ribeiro, Fernanda L., Zhu, Xiangyun, Aiken, Patrick, Bollmann, Saskia, Bollmann, Steffen, Chang, Jeryn, Chidley, Kali, Dempsey-Jones, Harriet, Eftekhari, Zeinab, Gillespie, Jennifer, Henderson, Robert D., Kiernan, Matthew C., Ktena, Ira, McCombe, Pamela A., Ngo, Shyuan T., Taubert, Shana T., Whelan, Brooke-Mai, Ye, Xincheng, Steyn, Frederik J., Tu, Sicong and Barth, Markus (2025). Segmentation of the human tongue musculature using MRI: Field guide and validation in motor neuron disease. Computers in Biology and Medicine, 196 (Part B) 110824, 1-13. doi: 10.1016/j.compbiomed.2025.110824 |
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2025 Journal Article Deciphering hypothalamic pathology in ALS: insights into non-motor symptoms and disease progressionChang, Jeryn, Teo, Annissa H., Shaw, Thomas B., Dupuis, Luc, Ngo, Shyuan T. and Steyn, Frederik J. (2025). Deciphering hypothalamic pathology in ALS: insights into non-motor symptoms and disease progression. eBioMedicine, 118 105845, 1-13. doi: 10.1016/j.ebiom.2025.105845 |
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2025 Journal Article Identification of passive wrist-worn accelerometry outcomes for improved disease monitoring and trial design in motor neuron diseaseHoldom, Cory J., Pilkar, Rakesh, Guo, Christine C., Eijk, Ruben P.A van, Sethi, Nadia, Henderson, Robert D., Ngo, Shyuan T. and Steyn, Frederik J. (2025). Identification of passive wrist-worn accelerometry outcomes for improved disease monitoring and trial design in motor neuron disease. eBioMedicine, 117 105779, 1-14. doi: 10.1016/j.ebiom.2025.105779 |
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2025 Journal Article Assessment of the “MND-Prism” smartphone application as a tool for self-managementNeville, Sally, Ziser, Laura, Henders, Anjali, Milne, Jane, Ngo, Shyuan T., Packer, Rebecca and Steyn, Frederik J. (2025). Assessment of the “MND-Prism” smartphone application as a tool for self-management. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 26 (7-8), 1-10. doi: 10.1080/21678421.2025.2511119 |
