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2012

Journal Article

SBAL: A practical tool to generate and edit structure-based amino acid sequence alignments

Wang, Conan K., Broder, Ursula, Weeratunga, Saroja K., Gasser, Robin B., Loukas, Alex and Hofmann, Andreas (2012). SBAL: A practical tool to generate and edit structure-based amino acid sequence alignments. Bioinformatics, 28 (7) bts035, 1026-1027. doi: 10.1093/bioinformatics/bts035

SBAL: A practical tool to generate and edit structure-based amino acid sequence alignments

2012

Journal Article

Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration

Xavier, Charles-Peter, Rastetter, Raphael H., Blomacher, Margit, Stumpf, Maria, Himmel, Mirko, Morgan, Reginald O., Fernandez, Maria-Pilar, Wang, Conan, Osman, Asiah, Miyata, Yoshihiko, Gjerset, Ruth A., Eichinger, Ludwig, Hofmann, Andreas, Linder, Stefan, Noegel, Angelika A. and Clemen, Christoph S. (2012). Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration. Scientific Reports, 2 (1) 241. doi: 10.1038/srep00241

Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration

2011

Journal Article

DMAN: a java tool for analysis of multi-well differential scanning fluorimetry experiments

Wang, Conan K., Weeratunga, Saroja K., Pacheco, Chris M. and Hofmann, Andreas (2011). DMAN: a java tool for analysis of multi-well differential scanning fluorimetry experiments. Bioinformatics, 28 (3) btr664, 439-440. doi: 10.1093/bioinformatics/btr664

DMAN: a java tool for analysis of multi-well differential scanning fluorimetry experiments

2011

Journal Article

Promiscuity of carbonic anhydrase II: Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors

Lopez, Marie, Vu. Hoan, Wang, Conan K., Wolf, Maarten G., Groenhof, Gerrit, Innocentis, Alessio, Supuran, Claudiu T. and Poulsen, Sally-Ann (2011). Promiscuity of carbonic anhydrase II: Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. Journal of The American Chemical Society, 133 (45), 18452-18462. doi: 10.1021/ja207855c

Promiscuity of carbonic anhydrase II: Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors

2011

Journal Article

Divalent cations and Redox conditions regulate the molecular structure and function of visinin-like protein-1

Wang, Conan K., Simon, Anne, Jessen, Christian M., Oliveira, Cristiano L. P., Mack, Lynsey, Braunewell, Karl-Heinz, Ames, James B., Pedersen, Jan Skov and Hofmann, Andreas (2011). Divalent cations and Redox conditions regulate the molecular structure and function of visinin-like protein-1. PLoS One, 6 (11) e26793, e26793.1-e26793.10. doi: 10.1371/journal.pone.0026793

Divalent cations and Redox conditions regulate the molecular structure and function of visinin-like protein-1

2011

Journal Article

Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm

Willis, Charlene, Wang, Conan K., Osman, Asiah, Simon, Anne, Pickering, Darren, Mulvenna, Jason, Riboldi-Tunicliffe, Alan, Jones, Malcolm K., Loukas, Alex and Hofmann, Andreas (2011). Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm. PLoS One, 6 (10) e25369, e25369.1-e25369.10. doi: 10.1371/journal.pone.0025369

Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm

2011

Journal Article

The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

Wang, Conan K. L., Clark, Richard J., Harvey, Peta J., Rosengren, K. Johan, Cemazar, Masa and Craik, David J. (2011). The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry, 50 (19), 4077-4086. doi: 10.1021/bi2004153

The role of conserved Glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant

2011

Journal Article

Atypical (RIO) protein kinases from Haemonchus contortus-promise as new targets for nematocidal drugs

Campbell, Bronwyn E., Boag, Peter R., Hofmann, Andreas, Cantacessi, Cinzia, Wang, Conan K., Taylor, Paul, Hu, Min, Sindhu, Zia-ud-Din, Loukas, Alex, Sternberg, Paul W. and Gasser, Robin B. (2011). Atypical (RIO) protein kinases from Haemonchus contortus-promise as new targets for nematocidal drugs. Biotechnology Advances, 29 (3), 338-350. doi: 10.1016/j.biotechadv.2011.01.006

Atypical (RIO) protein kinases from Haemonchus contortus-promise as new targets for nematocidal drugs

2010

Journal Article

Isolation and characterization of Bioactive Cyclotides from Viola labrilorica

Tang, Jun, Wang, Conan K., Pan, Xulin, Yan, He, Zeng, Guangzhi, Xu, Wenyan, He, Wenjun, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2010). Isolation and characterization of Bioactive Cyclotides from Viola labrilorica. Helvetica Chimica Acta, 93 (11), 2287-2295. doi: 10.1002/hlca.201000115

Isolation and characterization of Bioactive Cyclotides from Viola labrilorica

2010

Journal Article

Merging structural biology with chemical biology: Structural Chemistry at Eskitis

Hofmann, Andreas, Wang, Con, Osman, Asiah and Camp, David (2010). Merging structural biology with chemical biology: Structural Chemistry at Eskitis. Structural Chemistry, 21 (5), 1117-1129. doi: 10.1007/s11224-010-9654-2

Merging structural biology with chemical biology: Structural Chemistry at Eskitis

2010

Journal Article

Isolation and characterization of cytotoxic cyclotides from Viola tricolor

Tang, Jun, Wang, Conan K., Pan, Xulin, Yan, He, Zeng, Guangzhi, Xu, Wenyan, He, Wenjun, Daly, Norelle L., Craik, David J. and Tan, Ninghua (2010). Isolation and characterization of cytotoxic cyclotides from Viola tricolor. Peptides, 31 (8), 1434-1440. doi: 10.1016/j.peptides.2010.05.004

Isolation and characterization of cytotoxic cyclotides from Viola tricolor

2010

Journal Article

Extensions of PDZ domains as important structural and functional elements

Wang, Conan K., Pan, Lifeng, Chen, Jia and Zhang, Mingjie (2010). Extensions of PDZ domains as important structural and functional elements. Protein & Cell, 1 (8), 737-751. doi: 10.1007/s13238-010-0099-6

Extensions of PDZ domains as important structural and functional elements

2010

Journal Article

Cyclotides are a component of the innate defense of Oldenlandia affinis

Mylne, Joshua S, Wang, Conan K, van der Weerden, Nicole L and Craik, David J (2010). Cyclotides are a component of the innate defense of Oldenlandia affinis. Biopolymers, 94 (5), 635-646. doi: 10.1002/bip.21419

Cyclotides are a component of the innate defense of Oldenlandia affinis

2009

Journal Article

Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes

Wang, C. K., Colgrave, M. L., Ireland, D. C., Kaas, Q and Craik, D. J. (2009). Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes. Biophysical Journal, 97 (5), 1471-1481. doi: 10.1016/j.bpj.2009.06.032

Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes

2009

Journal Article

Isolation and characterization of peptides from momordica cochinchinensis seeds

Chan, L. Y., Wang, C. K., Major, J. M., Greenwood, K. P., Lewis, R. J., Craik, D. J. and Daly, N. L. (2009). Isolation and characterization of peptides from momordica cochinchinensis seeds. JOURNAL OF NATURAL PRODUCTS, 72 (8), 1453-1458. doi: 10.1021/np900174n

Isolation and characterization of peptides from momordica cochinchinensis seeds

2009

Journal Article

Combined x-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold

Wang, C. K., Hu, S. H., Martin, J. L., Sjogren, T, Hajdu, J, Bohlin, L, Claeson, P, Goransson, U, Rosengren, K. J., Tang, J, Tan, N. H. and Craik, D. J. (2009). Combined x-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold. Journal of Biological Chemistry, 284 (16), 10672-10683. doi: 10.1074/jbc.M900021200

Combined x-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold

2008

Journal Article

NMRDyn: a program for NMR relaxation studies of protein association

Wang, Conan K., Schirra, Horst Joachim and Craik, David J. (2008). NMRDyn: a program for NMR relaxation studies of protein association. PLoS One, 3 (11) e3820, e3820-1-e3820-7. doi: 10.1371/journal.pone.0003820

NMRDyn: a program for NMR relaxation studies of protein association

2008

Journal Article

CyBase: a database of cyclic protein sequences and structures, with application in protein discovery and engineering

Wang, C. K., Kaas, Q., Chiche, L. and Craik, D. J. (2008). CyBase: a database of cyclic protein sequences and structures, with application in protein discovery and engineering. Nucleic Acids Research, 36 (SUPPL. 1), D206-D210. doi: 10.1093/nar/gkm953

CyBase: a database of cyclic protein sequences and structures, with application in protein discovery and engineering

2008

Journal Article

The anthelmintic activity of the cyclotides: Natural variants with enhanced activity

Colgrave, Michelle L., Kotze, Andrew C., Ireland, David C., Wang, Conan K. and Craik, David J. (2008). The anthelmintic activity of the cyclotides: Natural variants with enhanced activity. ChemBioChem, 9 (12), 1939-1945. doi: 10.1002/cbic.200800174

The anthelmintic activity of the cyclotides: Natural variants with enhanced activity

2008

Journal Article

Distribution and evolution of circular miniproteins in flowering plants

Gruber, Christian W., Elliott, Alysha G., Ireland, David C., Delprete, Piero G., Dessein, Steven, Goransson, Ulf, Trabi, Manuela, Wang, Conan K., Kinghorn, Andrew B., Robbrecht, Elmar and Craik, David J. (2008). Distribution and evolution of circular miniproteins in flowering plants. The Plant Cell, 20 (9), 2471-2483. doi: 10.1105/tpc.108.062331

Distribution and evolution of circular miniproteins in flowering plants