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2020

Journal Article

Analysis of global collection of group A Streptococcus genomes reveals that the majority encode a trio of M and M-like proteins

Frost, Hannah R., Davies, Mark R., Delforge, Valérie, Lakhloufi, Dalila, Sanderson-Smith, Martina, Srinivasan, Velusamy, Steer, Andrew C., Walker, Mark J., Beall, Bernard, Botteaux, Anne and Smeesters, Pierre R. (2020). Analysis of global collection of group A Streptococcus genomes reveals that the majority encode a trio of M and M-like proteins. mSphere, 5 (1) e00806. doi: 10.1128/mSphere.00806-19

Analysis of global collection of group A Streptococcus genomes reveals that the majority encode a trio of M and M-like proteins

2020

Journal Article

Neisseria gonorrhoeae becomes susceptible to polymyxin B and colistin in the presence of PBT2

Jen, Freda E.-C., Everest-Dass, Arun V., El-Deeb, Ibrahim M., Singh, Sanjesh, Haselhorst, Thomas, Walker, Mark J., Von Itzstein, Mark and Jennings, Michael P. (2020). Neisseria gonorrhoeae becomes susceptible to polymyxin B and colistin in the presence of PBT2. ACS Infectious Diseases, 6 (1), 50-55. doi: 10.1021/acsinfecdis.9b00307

Neisseria gonorrhoeae becomes susceptible to polymyxin B and colistin in the presence of PBT2

2019

Journal Article

Increased incidence of scarlet fever — China, 1999−2018

You, Yuanhai, Qin, Ying, Walker, Mark J., Feng, Luzhao and Zhang, Jianzhong (2019). Increased incidence of scarlet fever — China, 1999−2018. China CDC Weekly, 1 (5), 63-66. doi: 10.46234/ccdcw2019.019

Increased incidence of scarlet fever — China, 1999−2018

2019

Journal Article

Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection

Ly, Diane, Donahue, Deborah, Walker, Mark J., Ploplis, Victoria A., McArthur, Jason D., Ranson, Marie, Castellino, Francis J. and Sanderson-Smith, Martina L. (2019). Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection. Microbes and Infection, 21 (8-9), 412-417. doi: 10.1016/j.micinf.2019.04.004

Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection

2019

Journal Article

Scarlet fever changes its spots

Brouwer, Stephan, Lacey, Jake A., You, Yuanhai, Davies, Mark R. and Walker, Mark J. (2019). Scarlet fever changes its spots. Lancet Infectious Diseases, 19 (11), 1154-1155. doi: 10.1016/S1473-3099(19)30494-3

Scarlet fever changes its spots

2019

Journal Article

Human glycan expression patterns influence Group A streptococcal colonization of epithelial cells

De Oliveira, David M. P., Everest-Dass, Arun, Hartley-Tassell, Lauren, Day, Christopher J., Indraratna, Anuk, Brouwer, Stephan, Cleary, Ailish, Kautto, Liisa, Gorman, Jody, Packer, Nicolle H., Jennings, Michael P., Walker, Mark J. and Sanderson-Smith, Martina L. (2019). Human glycan expression patterns influence Group A streptococcal colonization of epithelial cells. FASEB Journal, 33 (10), 10808-10818. doi: 10.1096/fj.201900559R

Human glycan expression patterns influence Group A streptococcal colonization of epithelial cells

2019

Journal Article

The serotype-specific role of regulator of cov polymorphisms in the pathogenesis of invasive group a streptococcal infections

Brouwer, Stephan and Walker, Mark J. (2019). The serotype-specific role of regulator of cov polymorphisms in the pathogenesis of invasive group a streptococcal infections. American Journal of Pathology, 189 (10), 1913-1915. doi: 10.1016/j.ajpath.2019.07.005

The serotype-specific role of regulator of cov polymorphisms in the pathogenesis of invasive group a streptococcal infections

2019

Journal Article

Author correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

Davies, Mark R., McIntyre, Liam, Mutreja, Ankur, Lacey, Jake A., Lees, John A., Towers, Rebecca J., Duchêne, Sebastián, Smeesters, Pierre R., Frost, Hannah R., Price, David J., Holden, Matthew T. G., David, Sophia, Giffard, Philip M., Worthing, Kate A., Seale, Anna C., Berkley, James A., Harris, Simon R., Rivera-Hernandez, Tania, Berking, Olga, Cork, Amanda J., Torres, Rosângela S. L. A., Lithgow, Trevor, Strugnell, Richard A., Bergmann, Rene, Nitsche-Schmitz, Patric, Chhatwal, Gusharan S., Bentley, Stephen D., Fraser, John D., Moreland, Nicole J. ... Walker, Mark J. (2019). Author correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics. Nature Genetics, 51 (8), 1295-1295. doi: 10.1038/s41588-019-0482-z

Author correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

2019

Journal Article

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

Davies, Mark R., McIntyre, Liam, Mutreja, Ankur, Lacey, Jake A., Lees, John A., Towers, Rebecca J., Duchêne, Sebastián, Smeesters, Pierre R., Frost, Hannah R., Price, David J., Holden, Matthew T. G., David, Sophia, Giffard, Philip M., Worthing, Kate A., Seale, Anna C., Berkley, James A., Harris, Simon R., Rivera-Hernandez, Tania, Berking, Olga, Cork, Amanda J., Torres, Rosângela S. L. A., Lithgow, Trevor, Strugnell, Richard A., Bergmann, Rene, Nitsche-Schmitz, Patric, Chhatwal, Gusharan S., Bentley, Stephen D., Fraser, John D., Moreland, Nicole J. ... Walker, Mark J. (2019). Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics. Nature Genetics, 51 (6), 1035-1043. doi: 10.1038/s41588-019-0417-8

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

2019

Journal Article

Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study

Osowicki, Joshua, Azzopardi, Kristy I., Baker, Ciara, Waddington, Claire S., Pandey, Manisha, Schuster, Tibor, Grobler, Anneke, Cheng, Allen C., Pollard, Andrew J., McCarthy, James S., Good, Michael F., Walker, Mark J., Dale, James B., Batzloff, Michael R., Carapetis, Jonathan R., Smeesters, Pierre R. and Steer, Andrew C. (2019). Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study. Vaccine, 37 (26), 3485-3494. doi: 10.1016/j.vaccine.2019.03.059

Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study

2019

Journal Article

An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model

Rivera-Hernandez, Tania, Carnathan, Diane G., Jones, Scott, Cork, Amanda J., Davies, Mark R., Moyle, Peter M., Toth, Istvan, Batzloff, Michael R., McCarthy, James, Nizet, Victor, Goldblatt, David, Silvestri, Guido and Walker, Mark J. (2019). An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model. mBio, 10 (2) e00693-19. doi: 10.1128/mBio.00693-19

An experimental Group A Streptococcus vaccine that reduces pharyngitis and tonsillitis in a nonhuman primate model

2019

Journal Article

Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides

Edgar, Rebecca J., van Hensbergen, Vincent P., Ruda, Alessandro, Turner, Andrew G., Deng, Pan, Le Breton, Yoann, El-Sayed, Najib M., Belew, Ashton T., McIver, Kevin S., McEwan, Alastair G., Morris, Andrew J., Lambeau, Gérard, Walker, Mark J., Rush, Jeffrey S., Korotkov, Konstantin V., Widmalm, Göran, van Sorge, Nina M. and Korotkova, Natalia (2019). Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides. Nature Chemical Biology, 15 (5), 463-471. doi: 10.1038/s41589-019-0251-4

Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides

2019

Journal Article

Group A Streptococcus co-ordinates manganese import and iron efflux in response to hydrogen peroxide stress

Turner, Andrew G., Djoko, Karrera Y., Ong, Cheryl-Lynn Y., Barnett, Timothy C., Walker, Mark J. and McEwan, Alastair G. (2019). Group A Streptococcus co-ordinates manganese import and iron efflux in response to hydrogen peroxide stress. Biochemical Journal, 476 (3), 595-611. doi: 10.1042/BCJ20180902

Group A Streptococcus co-ordinates manganese import and iron efflux in response to hydrogen peroxide stress

2019

Journal Article

A controlled human infection model of Group A Streptococcus pharyngitis: which strain and why?

Osowicki, Joshua, Azzopardi, Kristy I., McIntyre, Liam, Rivera-Hernandez, Tania, Ong, Cheryl-Lynn Y., Baker, Ciara, Gillen, Christine M., Walker, Mark J., Smeesters, Pierre R., Davies, Mark R. and Steer, Andrew C. (2019). A controlled human infection model of Group A Streptococcus pharyngitis: which strain and why?. mSphere, 4 (1) e00647-18, e00647-18. doi: 10.1128/mSphere.00647-18

A controlled human infection model of Group A Streptococcus pharyngitis: which strain and why?

2019

Journal Article

Detection of epidemic scarlet fever group A Streptococcus in Australia

Walker, Mark J., Brouwer, Stephan, Forde, Brian M., Worthing, Kate A., McIntyre, Liam, Sundac, Lana, Maloney, Sam, Roberts, Leah W., Barnett, Timothy C., Richter, Johanna, Cork, Amanda J., Irwin, Adam D., You, Yuanhai, Zhang, Jianzhong, Dougan, Gordon, Yuen, K. Y., Nizet, Victor, Beatson, Scott A., Grimwood, Keith and Davies, Mark R. (2019). Detection of epidemic scarlet fever group A Streptococcus in Australia. Clinical Infectious Diseases, 69 (7), 1232-1234. doi: 10.1093/cid/ciz099

Detection of epidemic scarlet fever group A Streptococcus in Australia

2018

Journal Article

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18. doi: 10.1128/mbio.02391-18

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

2018

Journal Article

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18, 1-12. doi: 10.1128/mBio.02391-18

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

2018

Journal Article

Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection

Imai, Takashi, Matsumura, Takayuki, Mayer-Lambertz, Sabine, Wells, Christine A., Ishikawa, Eri, Butcher, Suzanne K., Barnett, Timothy C., Walker, Mark J., Imamura, Akihiro, Ishida, Hideharu, Ikebe, Tadayoshi, Miyamoto, Tomofumi, Ato, Manabu, Ohga, Shouichi, Lepenies, Bernd, van Sorge, Nina M. and Yamasaki, Sho (2018). Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection. Proceedings of the National Academy of Sciences of the United States of America, 115 (45), E10662-E10671. doi: 10.1073/pnas.1809100115

Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection

2018

Journal Article

Hypotheses for the resurgence of scarlet fever in China

You, Yuanhai, Davies, Mark R, Walker, Mark J and Zhang, Jianzhong (2018). Hypotheses for the resurgence of scarlet fever in China. The Lancet Infectious Diseases, 18 (9), 942-943. doi: 10.1016/S1473-3099(18)30470-5

Hypotheses for the resurgence of scarlet fever in China

2018

Journal Article

Microevolution of aquatic Streptococcus agalactiae ST-261 from Australia indicates dissemination via imported tilapia and ongoing adaptation to marine hosts or environment

Kawasaki, Minami, Delamare-Deboutteville, Jerome, Bowater, Rachel O, Walker, Mark J., Beatson, Scott, Ben Zakour, Nouri L. and Barnes, Andrew C. (2018). Microevolution of aquatic Streptococcus agalactiae ST-261 from Australia indicates dissemination via imported tilapia and ongoing adaptation to marine hosts or environment. Applied and Environmental Microbiology, 84 (16) e00859-18, AEM.00859-18. doi: 10.1128/aem.00859-18

Microevolution of aquatic Streptococcus agalactiae ST-261 from Australia indicates dissemination via imported tilapia and ongoing adaptation to marine hosts or environment