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Featured 2026 Journal Article Emergence of distinct Streptococcus pyogenes emm1 and emm12 lineages in ChinaYou, Yuanhai, Yu, Dingle, Yang, Chao, Peng, Xiaomin, Xie, Ouli, Chang, Hesheng, Hua, Chunzhen, Zhao, Fei, Yan, Xiaomei, Zhang, Menghan, Ruan, Xinwei, Wells, Jasmine E. J., Brouwer, Stephan, Duitama González, Camila, Fang, Ming, Yu, Xiaojie, Sun, Lu, Wei, Xiaoyue, Liu, Jie, Zhang, Daitao, He, Lihua, Wang, Jiazheng, Sun, Chuyang, Zheng, Yuejie, Duchene, Sebastian, Zhou, Mingming, Sun, Lifang, Davies, Mark R., Walker, Mark J. ... Yang, Yonghong (2026). Emergence of distinct Streptococcus pyogenes emm1 and emm12 lineages in China. Nature Microbiology, 11 (5), 1245-1255. doi: 10.1038/s41564-026-02324-4 |
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Featured 2025 Journal Article An mRNA vaccine encoding five conserved Group A Streptococcus antigensHarbison-Price, Nichaela, Sebina, Ismail, Bolton, Rhiannon A., Finn, Meredith, Cork, Amanda J., Courtney, Isabel G., Hancock, Steven, Pelingon, Ruby, Richter, Johanna, Ericsson, Olivia, Green, Shannon, Cuellar, Celeste, Davis, Laura, Pullinger, Brody, Na, Jack, Elangovan, Gayathiri, De Oliveira, David M. P., Curren, Bodie F., Bickham, Nia, Aguirre, Miguel, Dold, Christina, Brouwer, Stephan, Plante, Obadiah, Belz, Gabrielle T. and Walker, Mark J. (2025). An mRNA vaccine encoding five conserved Group A Streptococcus antigens. Nature Communications, 16 (1) 5439, 1-14. doi: 10.1038/s41467-025-60580-0 |
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Featured 2023 Journal Article Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteriaMu, Andre, Klare, William P., Baines, Sarah L., Ignatius Pang, C. N., Guérillot, Romain, Harbison-Price, Nichaela, Keller, Nadia, Wilksch, Jonathan, Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Keller, Bernhard, Nijagal, Brunda, Tull, Dedreia, Dayalan, Saravanan, Chua, Hwa Huat Charlie, Skoneczny, Dominik, Koval, Jason, Hachani, Abderrahman, Shah, Anup D., Neha, Nitika, Jadhav, Snehal, Partridge, Sally R., Cork, Amanda J., Peters, Kate, Bertolla, Olivia, Brouwer, Stephan, Hancock, Steven J., Álvarez-Fraga, Laura, De Oliveira, David M. P. ... Walker, Mark J. (2023). Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria. Nature Communications, 14 (1) 1530, 1-21. doi: 10.1038/s41467-023-37200-w |
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Featured 2023 Journal Article Pathogenesis, epidemiology and control of Group A Streptococcus infectionBrouwer, Stephan, Rivera-Hernandez, Tania, Curren, Bodie F., Harbison-Price, Nichaela, De Oliveira, David M. P., Jespersen, Magnus G., Davies, Mark R. and Walker, Mark J. (2023). Pathogenesis, epidemiology and control of Group A Streptococcus infection. Nature Reviews Microbiology, 21 (7), 431-447. doi: 10.1038/s41579-023-00865-7 |
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Featured 2023 Journal Article Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeADavies, Mark R., Keller, Nadia, Brouwer, Stephan, Jespersen, Magnus G., Cork, Amanda J., Hayes, Andrew J., Pitt, Miranda E., De Oliveira, David M. P., Harbison-Price, Nichaela, Bertolla, Olivia M., Mediati, Daniel G., Curren, Bodie F., Taiaroa, George, Lacey, Jake A., Smith, Helen V., Fang, Ning-Xia, Coin, Lachlan J. M., Stevens, Kerrie, Tong, Steven Y. C., Sanderson-Smith, Martina, Tree, Jai J., Irwin, Adam D., Grimwood, Keith, Howden, Benjamin P., Jennison, Amy V. and Walker, Mark J. (2023). Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA. Nature Communications, 14 (1) 1051, 1-12. doi: 10.1038/s41467-023-36717-4 |
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Featured 2020 Journal Article Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenesBrouwer, Stephan, Barnett, Timothy C., Ly, Diane, Kasper, Katherine J., De Oliveira, David M. P., Rivera-Hernandez, Tania, Cork, Amanda J., McIntyre, Liam, Jespersen, Magnus G., Richter, Johanna, Schulz, Benjamin L., Dougan, Gordon, Nizet, Victor, Yuen, Kwok-Yung, You, Yuanhai, McCormick, John K., Sanderson-Smith, Martina L., Davies, Mark R. and Walker, Mark J. (2020). Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes. Nature Communications, 11 (1) 5018, 5018. doi: 10.1038/s41467-020-18700-5 |
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Featured 2020 Journal Article Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsisDe Oliveira, David M. P., Bohlmann, Lisa, Conroy, Trent, Jen, Freda E.-C., Everest-Dass, Arun, Hansford, Karl A., Bolisetti, Raghu, El-Deeb, Ibrahim M., Forde, Brian M., Phan, Minh-Duy, Lacey, Jake A., Tan, Aimee, Rivera-Hernandez, Tania, Brouwer, Stephan, Keller, Nadia, Kidd, Timothy J., Cork, Amanda J., Bauer, Michelle J., Cook, Gregory M., Davies, Mark R., Beatson, Scott A., Paterson, David L., McEwan, Alastair G., Li, Jian, Schembri, Mark A., Blaskovich, Mark A. T., Jennings, Michael P., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2020). Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis. Science Translational Medicine, 12 (570) abb3791, eabb3791. doi: 10.1126/scitranslmed.abb3791 |
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Featured 2019 Journal Article Scarlet fever changes its spotsBrouwer, Stephan, Lacey, Jake A., You, Yuanhai, Davies, Mark R. and Walker, Mark J. (2019). Scarlet fever changes its spots. Lancet Infectious Diseases, 19 (11), 1154-1155. doi: 10.1016/S1473-3099(19)30494-3 |
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Featured 2019 Journal Article Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomicsDavies, Mark R., McIntyre, Liam, Mutreja, Ankur, Lacey, Jake A., Lees, John A., Towers, Rebecca J., Duchêne, Sebastián, Smeesters, Pierre R., Frost, Hannah R., Price, David J., Holden, Matthew T. G., David, Sophia, Giffard, Philip M., Worthing, Kate A., Seale, Anna C., Berkley, James A., Harris, Simon R., Rivera-Hernandez, Tania, Berking, Olga, Cork, Amanda J., Torres, Rosângela S. L. A., Lithgow, Trevor, Strugnell, Richard A., Bergmann, Rene, Nitsche-Schmitz, Patric, Chhatwal, Gusharan S., Bentley, Stephen D., Fraser, John D., Moreland, Nicole J. ... Walker, Mark J. (2019). Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics. Nature Genetics, 51 (6), 1035-1043. doi: 10.1038/s41588-019-0417-8 |
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Featured 2018 Journal Article Scarlet fever makes a comebackWalker, Mark J. and Brouwer, Stephan (2018). Scarlet fever makes a comeback. The Lancet Infectious Diseases, 18 (2), 128-129. doi: 10.1016/S1473-3099(17)30694-1 |
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Featured 2015 Journal Article Emergence of scarlet fever Streptococcus pyogenes emm12 clones in Hong Kong is associated with toxin acquisition and multidrug resistanceDavies, Mark R., Holden, Matthew T., Coupland, Paul, Chen, Jonathan H. K., Venturini, Carola, Barnett, Timothy C., Ben Zakour, Nouri L., Tse, Herman, Dougan, Gordon, Yuen, Kwok-Yung and Walker, Mark J. (2015). Emergence of scarlet fever Streptococcus pyogenes emm12 clones in Hong Kong is associated with toxin acquisition and multidrug resistance. Nature Genetics, 47 (1), 84-87+. doi: 10.1038/ng.3147 |
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Featured 2013 Journal Article The globally disseminated M1T1 clone of Group A Streptococcus evades autophagy for intracellular replicationBarnett, Timothy C., Liebl, David, Seymour, Lisa M., Gillen, Christine M., Lim, Jin Yan, LaRock, Christopher N., Davies, Mark R., Schulz, Benjamin L., Nizet, Victor, Teasdale, Rohan D. and Walker, Mark J. (2013). The globally disseminated M1T1 clone of Group A Streptococcus evades autophagy for intracellular replication. Cell Host and Microbe, 14 (6), 675-682. doi: 10.1016/j.chom.2013.11.003 |
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Featured 2012 Journal Article Outsmarting outbreaksWalker, Mark J. and Beatson, Scott A. (2012). Outsmarting outbreaks. Science, 338 (6111), 1161-1162. doi: 10.1126/science.1232327 |
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Featured 2011 Journal Article Molecular insight into invasive group A streptococcal diseaseCole, Jason N., Barnett, Timothy C., Nizet, Victor and Walker, Mark J. (2011). Molecular insight into invasive group A streptococcal disease. Nature Reviews Microbiology, 9 (10), 724-736. doi: 10.1038/nrmicro2648 |
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Featured 2007 Journal Article DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infectionWalker, Mark J., Hollands, Andrew, Sanderson-Smith, Martina L., Cole, Jason N., Kirk, Joshua K., Henningham, Anna, McArthur, Jason D., Dinkla, Katrin, Aziz, Ramy K., Kansal, Rita G., Simpson, Amelia J., Buchanan, John T., Chhatwal, Gursharan S., Kotb, Malak and Nizet, Malak (2007). DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection. Nature Medicine, 13 (8), 981-985. doi: 10.1038/nm1612 |
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2026 Journal Article Current progress in developing mRNA-lipid nanoparticle vaccines against human bacterial pathogensPullinger, Brody, Harbison-Price, Nichaela, Sebina, Ismail, Na, Jack, Belz, Gabrielle T. and Walker, Mark J. (2026). Current progress in developing mRNA-lipid nanoparticle vaccines against human bacterial pathogens. Clinical Microbiology Reviews e00138-26, e0013826-e0013826. doi: 10.1128/cmr.00138-26 |
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2026 Journal Article Newly identified antimicrobial activity of an 8-hydroxyquinoline-based ionophore against multidrug-resistant Enterococcus faecium and Staphylococcus aureusLi, Gen, El-Deeb, Ibrahim M., Whyte, Hayden G., Blaskovich, Mark A. T., Walker, Mark J., von Itzstein, Mark and De Oliveira, David M. P. (2026). Newly identified antimicrobial activity of an 8-hydroxyquinoline-based ionophore against multidrug-resistant Enterococcus faecium and Staphylococcus aureus. Journal of Antimicrobial Chemotherapy, 81 (7). doi: 10.1093/jac/dkag186 |
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2026 Journal Article Overcoming methicillin resistance in Staphylococcus aureus via metal ion disruption of bacterial metabolismMacbeth, Ella K., Todd Rose, Francesca, Cheung, Chen-Yi, Harbison-Price, Nichaela, De Oliveira, David M. P., Whyte, Hayden G., Walker, Mark J., Hussein, Maytham, Velkov, Tony, Neville, Stephanie L., McDevitt, Christopher A., Monk, Ian R., Ferguson, Scott A. and Cook, Gregory M. (2026). Overcoming methicillin resistance in Staphylococcus aureus via metal ion disruption of bacterial metabolism. npj Antimicrobials and Resistance. doi: 10.1038/s44259-026-00233-4 |
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2026 Journal Article Molecular characterization of covRS mutations in M1UK Streptococcus pyogenesPritchard, Jarrad, Proctor, Emma-Jayne, Wang, Jiawa, Johnston, Nikolas P., Hayes, Andrew, McCorkell, Georgia, Yu, Haibo, Tree, Jai, Davies, Mark R., Walker, Mark J., Sluyter, Ronald, Brouwer, Stephan and Sanderson-Smith, Martina L. (2026). Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes. Febs Open Bio. doi: 10.1002/2211-5463.70275 |
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2026 Journal Article Preclinical Pharmacokinetics and Pharmacodynamics of Antibiotic AdjuvantsPham, Viet Tin, De Oliveira, David M. P., Kuo, Andy, Walker, Mark J. and Smith, Maree T. (2026). Preclinical Pharmacokinetics and Pharmacodynamics of Antibiotic Adjuvants. ACS Infectious Diseases, 12 (6) acsinfecdis.5c01065, 1794-1818. doi: 10.1021/acsinfecdis.5c01065 |
