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2020

Journal Article

Antimicrobial resistance in ESKAPE pathogens

De Oliveira, David M. P., Forde, Brian M., Kidd, Timothy J., Harris, Patrick N. A., Schembri, Mark A., Beatson, Scott A., Paterson, David L. and Walker, Mark J. (2020). Antimicrobial resistance in ESKAPE pathogens. Clinical Microbiology Reviews, 33 (3) e00181-19, e00181-19. doi: 10.1128/cmr.00181-19

Antimicrobial resistance in ESKAPE pathogens

2020

Journal Article

Update on group A streptococcal vaccine development

Dale, James B. and Walker, Mark J. (2020). Update on group A streptococcal vaccine development. Current Opinion in Infectious Diseases, 33 (3), 244-250. doi: 10.1097/QCO.0000000000000644

Update on group A streptococcal vaccine development

2020

Journal Article

All major cholesterol-dependent cytolysins use glycans as cellular receptors

Shewell, Lucy K., Day, Christopher J., Jen, Freda E.-C., Haselhorst, Thomas, Atack, John M., Reijneveld, Josephine F., Everest-Dass, Arun, James, David B. A., Boguslawski, Kristina M., Brouwer, Stephan, Gillen, Christine M., Luo, Zhenyao, Kobe, Bostjan, Nizet, Victor, von Itzstein, Mark, Walker, Mark J., Paton, Adrienne W., Paton, James C., Torres, Victor J. and Jennings, Michael P. (2020). All major cholesterol-dependent cytolysins use glycans as cellular receptors. Science Advances, 6 (21) EAAZ4926, eaaz4926. doi: 10.1126/sciadv.aaz4926

All major cholesterol-dependent cytolysins use glycans as cellular receptors

2020

Journal Article

Multiple bactericidal mechanisms of the zinc ionophore PBT2

Harbison-Price, Nichaela, Ferguson, Scott A., Heikal, Adam, Taiaroa, George, Hards, Kiel, Nakatani, Yoshio, Rennison, David, Brimble, Margaret A., El-Deeb, Ibrahim M., Bohlmann, Lisa, McDevitt, Christopher A., von Itzstein, Mark, Walker, Mark J. and Cook, Gregory M. (2020). Multiple bactericidal mechanisms of the zinc ionophore PBT2. mSphere, 5 (2) e00157-20. doi: 10.1128/msphere.00157-20

Multiple bactericidal mechanisms of the zinc ionophore PBT2

2020

Journal Article

Vaccine-induced Th1-type response protects against invasive group A Streptococcus infection in the absence of opsonizing antibodies

Rivera-Hernandez, Tania, Rhyme, Mira Syahira, Cork, Amanda J., Jones, Scott, Segui-Perez, Celia, Brunner, Livia, Richter, Johanna, Petrovsky, Nikolai, Lawrenz, Maria, Goldblatt, David, Collin, Nicolas and Walker, Mark J. (2020). Vaccine-induced Th1-type response protects against invasive group A Streptococcus infection in the absence of opsonizing antibodies. mBio, 11 (2) e00122-20. doi: 10.1128/mbio.00122-20

Vaccine-induced Th1-type response protects against invasive group A Streptococcus infection in the absence of opsonizing antibodies

2020

Journal Article

Updated emm-typing protocol for Streptococcus pyogenes

Frost, H. R., Davies, M. R., Velusamy, S., Delforge, V., Erhart, A., Darboe, S., Steer, A., Walker, M. J., Beall, B., Botteaux, A. and Smeesters, P. R. (2020). Updated emm-typing protocol for Streptococcus pyogenes. Clinical Microbiology and Infection, 26 (7) 946.e5, 946.e5-946.e8. doi: 10.1016/j.cmi.2020.02.026

Updated emm-typing protocol for Streptococcus pyogenes

2020

Journal Article

Semisynthetic, self-adjuvanting vaccine development: efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccine

Xu, Zhenghui, Rivera-Hernandez, Tania, Chatterjee, Oishee, Walker, Mark J. and Moyle, Peter M. (2020). Semisynthetic, self-adjuvanting vaccine development: efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccine. Journal of Controlled Release, 317, 96-108. doi: 10.1016/j.jconrel.2019.11.018

Semisynthetic, self-adjuvanting vaccine development: efficient, site-specific sortase A-mediated conjugation of Toll-like receptor 2 ligand FSL-1 to recombinant protein antigens under native conditions and application to a model group A streptococcal vaccine

2020

Journal Article

Analysis of global collection of group A Streptococcus genomes reveals that the majority encode a trio of M and M-like proteins

Frost, Hannah R., Davies, Mark R., Delforge, Valérie, Lakhloufi, Dalila, Sanderson-Smith, Martina, Srinivasan, Velusamy, Steer, Andrew C., Walker, Mark J., Beall, Bernard, Botteaux, Anne and Smeesters, Pierre R. (2020). Analysis of global collection of group A Streptococcus genomes reveals that the majority encode a trio of M and M-like proteins. mSphere, 5 (1) e00806. doi: 10.1128/mSphere.00806-19

Analysis of global collection of group A Streptococcus genomes reveals that the majority encode a trio of M and M-like proteins

2020

Book Chapter

Investigation of Group A Streptococcal interactions with host glycan structures using high-throughput techniques: glycan microarray analysis using recombinant protein and whole cells

Indraratna, Anuk, De Oliveira, David M. P., Hartley-Tassell, Lauren E., Day, Christopher J., Walker, Mark J., Jennings, Michael P. and Sanderson-Smith, Martina L. (2020). Investigation of Group A Streptococcal interactions with host glycan structures using high-throughput techniques: glycan microarray analysis using recombinant protein and whole cells. Group A Streptococcus: methods and protocols. (pp. 145-151) edited by Thomas Proft and Jacelyn M. S. Loh. New York, NY USA: Springer Nature. doi: 10.1007/978-1-0716-0467-0_10

Investigation of Group A Streptococcal interactions with host glycan structures using high-throughput techniques: glycan microarray analysis using recombinant protein and whole cells

2020

Book Chapter

Genetic manipulation of Group A Streptococcus - gene deletion by allelic replacement

Barnett, Timothy C., Daw, Jessica N., Walker, Mark J. and Brouwer, Stephan (2020). Genetic manipulation of Group A Streptococcus - gene deletion by allelic replacement. Group A Streptococcus: methods and protocols. (pp. 59-69) edited by Thomas Proft and Jacelyn M. S. Loh. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0467-0_5

Genetic manipulation of Group A Streptococcus - gene deletion by allelic replacement

2020

Journal Article

Neisseria gonorrhoeae becomes susceptible to polymyxin B and colistin in the presence of PBT2

Jen, Freda E.-C., Everest-Dass, Arun V., El-Deeb, Ibrahim M., Singh, Sanjesh, Haselhorst, Thomas, Walker, Mark J., Von Itzstein, Mark and Jennings, Michael P. (2020). Neisseria gonorrhoeae becomes susceptible to polymyxin B and colistin in the presence of PBT2. ACS Infectious Diseases, 6 (1), 50-55. doi: 10.1021/acsinfecdis.9b00307

Neisseria gonorrhoeae becomes susceptible to polymyxin B and colistin in the presence of PBT2

2020

Book Chapter

Humanized plasminogen mouse model to Study Group A Streptococcus invasive disease

Rivera-Hernandez, Tania and Walker, Mark J. (2020). Humanized plasminogen mouse model to Study Group A Streptococcus invasive disease. Group A Streptococcus: methods and protocols. (pp. 309-316) edited by Thomas Proft and Jacelyn M. S. Loh. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-0467-0_24

Humanized plasminogen mouse model to Study Group A Streptococcus invasive disease

2019

Journal Article

Increased incidence of scarlet fever — China, 1999−2018

You, Yuanhai, Qin, Ying, Walker, Mark J., Feng, Luzhao and Zhang, Jianzhong (2019). Increased incidence of scarlet fever — China, 1999−2018. China CDC Weekly, 1 (5), 63-66. doi: 10.46234/ccdcw2019.019

Increased incidence of scarlet fever — China, 1999−2018

2019

Journal Article

Scarlet fever changes its spots

Brouwer, Stephan, Lacey, Jake A., You, Yuanhai, Davies, Mark R. and Walker, Mark J. (2019). Scarlet fever changes its spots. Lancet Infectious Diseases, 19 (11), 1154-1155. doi: 10.1016/S1473-3099(19)30494-3

Scarlet fever changes its spots

2019

Journal Article

Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection

Ly, Diane, Donahue, Deborah, Walker, Mark J., Ploplis, Victoria A., McArthur, Jason D., Ranson, Marie, Castellino, Francis J. and Sanderson-Smith, Martina L. (2019). Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection. Microbes and Infection, 21 (8-9), 412-417. doi: 10.1016/j.micinf.2019.04.004

Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection

2019

Journal Article

The serotype-specific role of regulator of cov polymorphisms in the pathogenesis of invasive group a streptococcal infections

Brouwer, Stephan and Walker, Mark J. (2019). The serotype-specific role of regulator of cov polymorphisms in the pathogenesis of invasive group a streptococcal infections. American Journal of Pathology, 189 (10), 1913-1915. doi: 10.1016/j.ajpath.2019.07.005

The serotype-specific role of regulator of cov polymorphisms in the pathogenesis of invasive group a streptococcal infections

2019

Journal Article

Human glycan expression patterns influence Group A streptococcal colonization of epithelial cells

De Oliveira, David M. P., Everest-Dass, Arun, Hartley-Tassell, Lauren, Day, Christopher J., Indraratna, Anuk, Brouwer, Stephan, Cleary, Ailish, Kautto, Liisa, Gorman, Jody, Packer, Nicolle H., Jennings, Michael P., Walker, Mark J. and Sanderson-Smith, Martina L. (2019). Human glycan expression patterns influence Group A streptococcal colonization of epithelial cells. FASEB Journal, 33 (10), 10808-10818. doi: 10.1096/fj.201900559R

Human glycan expression patterns influence Group A streptococcal colonization of epithelial cells

2019

Journal Article

Author correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

Davies, Mark R., McIntyre, Liam, Mutreja, Ankur, Lacey, Jake A., Lees, John A., Towers, Rebecca J., Duchêne, Sebastián, Smeesters, Pierre R., Frost, Hannah R., Price, David J., Holden, Matthew T. G., David, Sophia, Giffard, Philip M., Worthing, Kate A., Seale, Anna C., Berkley, James A., Harris, Simon R., Rivera-Hernandez, Tania, Berking, Olga, Cork, Amanda J., Torres, Rosângela S. L. A., Lithgow, Trevor, Strugnell, Richard A., Bergmann, Rene, Nitsche-Schmitz, Patric, Chhatwal, Gusharan S., Bentley, Stephen D., Fraser, John D., Moreland, Nicole J. ... Walker, Mark J. (2019). Author correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics. Nature Genetics, 51 (8), 1295-1295. doi: 10.1038/s41588-019-0482-z

Author correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

2019

Journal Article

Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study

Osowicki, Joshua, Azzopardi, Kristy I., Baker, Ciara, Waddington, Claire S., Pandey, Manisha, Schuster, Tibor, Grobler, Anneke, Cheng, Allen C., Pollard, Andrew J., McCarthy, James S., Good, Michael F., Walker, Mark J., Dale, James B., Batzloff, Michael R., Carapetis, Jonathan R., Smeesters, Pierre R. and Steer, Andrew C. (2019). Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study. Vaccine, 37 (26), 3485-3494. doi: 10.1016/j.vaccine.2019.03.059

Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study

2019

Journal Article

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

Davies, Mark R., McIntyre, Liam, Mutreja, Ankur, Lacey, Jake A., Lees, John A., Towers, Rebecca J., Duchêne, Sebastián, Smeesters, Pierre R., Frost, Hannah R., Price, David J., Holden, Matthew T. G., David, Sophia, Giffard, Philip M., Worthing, Kate A., Seale, Anna C., Berkley, James A., Harris, Simon R., Rivera-Hernandez, Tania, Berking, Olga, Cork, Amanda J., Torres, Rosângela S. L. A., Lithgow, Trevor, Strugnell, Richard A., Bergmann, Rene, Nitsche-Schmitz, Patric, Chhatwal, Gusharan S., Bentley, Stephen D., Fraser, John D., Moreland, Nicole J. ... Walker, Mark J. (2019). Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics. Nature Genetics, 51 (6), 1035-1043. doi: 10.1038/s41588-019-0417-8

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics