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2022 Journal Article Structure-activity relationship of lipid, cyclic peptide and antigen rearrangement of physically mixed vaccinesHuang, Wenbin, Madge, Harrison Y. R., Zhang, Jiahui, Gilmartin, Lachlan, Hussein, Waleed M., Khalil, Zeinab G., Koirala, Prashamsa, Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2022). Structure-activity relationship of lipid, cyclic peptide and antigen rearrangement of physically mixed vaccines. International Journal of Pharmaceutics, 617 121614, 1-12. doi: 10.1016/j.ijpharm.2022.121614 |
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2022 Journal Article Investigation of liposomal self-adjuvanting peptide epitopes derived from conserved blood-stage Plasmodium antigensIslam, Md. Tanjir, Ho, Mei-Fong, Nahar, Ummey J., Shalash, Ahmed O., Koirala, Prashamsa, Hussein, Waleed M., Stanisic, Danielle I., Good, Michael F., Skwarczynski, Mariusz and Toth, Istvan (2022). Investigation of liposomal self-adjuvanting peptide epitopes derived from conserved blood-stage Plasmodium antigens. PLoS One, 17 (3) e0264961, e0264961. doi: 10.1371/journal.pone.0264961 |
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2022 Journal Article Peptide-based nanovaccines in the treatment of cervical cancer: a review of recent advancesZhang, Jiahui, Fan, Jingyi, Skwarczynski, Mariusz, Stephenson, Rachel J, Toth, Istvan and Hussein, Waleed M (2022). Peptide-based nanovaccines in the treatment of cervical cancer: a review of recent advances. International Journal of Nanomedicine, 17, 869-900. doi: 10.2147/ijn.s269986 |
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2022 Journal Article Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcusMadge, Harrison Y. R., Huang, Wenbin, Gilmartin, Lachlan, Rigau-Planella, Berta, Hussein, Waleed M., Khalil, Zeinab G., Koirala, Prashamsa, Santiago, Viviene S., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2022). Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcus. Biomaterials Science, 10 (1), 281-293. doi: 10.1039/d1bm01333e |
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2021 Journal Article Hookworm infection: toward development of safe and effective peptide vaccinesShalash, Ahmed O., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2021). Hookworm infection: toward development of safe and effective peptide vaccines. Journal of Allergy and Clinical Immunology, 148 (6), 1394-1419.e6. doi: 10.1016/j.jaci.2021.10.013 |
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2021 Journal Article Histone deacetylase inhibitors: providing new insights and therapeutic avenues for unlocking human birthIlicic, Marina, Zakar, Tamas, Gregson, Amy, Hussein, Waleed M., Smith, Roger and Paul, Jonathan W. (2021). Histone deacetylase inhibitors: providing new insights and therapeutic avenues for unlocking human birth. Reproductive Sciences, 29 (11), 1-13. doi: 10.1007/s43032-021-00778-x |
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2021 Journal Article Development and evaluation of a cryopreserved whole-parasite vaccine in a rodent model of blood-stage malariaStanisic, Danielle I., Ho, Mei-Fong, Nevagi, Reshma, Cooper, Emily, Walton, Maddison, Islam, Md Tanjir, Hussein, Waleed M., Skwarczynski, Mariusz, Toth, Istvan and Good, Michael F. (2021). Development and evaluation of a cryopreserved whole-parasite vaccine in a rodent model of blood-stage malaria. mBio, 12 (5) e02657-21, e0265721. doi: 10.1128/mBio.02657-21 |
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2021 Journal Article Oral peptide vaccine against hookworm infection: correlation of antibody titers with protective efficacyShalash, Ahmed O., Becker, Luke, Yang, Jieru, Giacomin, Paul, Pearson, Mark, Hussein, Waleed M., Loukas, Alex, Skwarczynski, Mariusz and Toth, Istvan (2021). Oral peptide vaccine against hookworm infection: correlation of antibody titers with protective efficacy. Vaccines, 9 (9) 1034, 1034. doi: 10.3390/vaccines9091034 |
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2021 Journal Article Poly(hydrophobic amino acid) conjugates for the delivery of multiepitope vaccine against Group A StreptococcusAzuar, Armira, Shibu, Mohini A., Adilbish, Nomin, Marasini, Nirmal, Hung, Hong, Yang, Jieru, Luo, Yacheng, Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Poly(hydrophobic amino acid) conjugates for the delivery of multiepitope vaccine against Group A Streptococcus. Bioconjugate Chemistry, 32 (11) acs.bioconjchem.1c00333, 2307-2317. doi: 10.1021/acs.bioconjchem.1c00333 |
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2021 Journal Article Rational design of potent inhibitors of a metallohydrolase using a fragment-based approachFeder, Daniel, Mohd-Pahmi, Siti H., Hussein, Waleed M., Guddat, Luke W., McGeary, Ross P. and Schenk, Gerhard (2021). Rational design of potent inhibitors of a metallohydrolase using a fragment-based approach. ChemMedChem, 16 (21) cmdc.202100486, 3342-3359. doi: 10.1002/cmdc.202100486 |
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2021 Journal Article Key considerations for the development of safe and effective SARS‐CoV‐2 subunit vaccine: a peptide‐based vaccine alternativeShalash, Ahmed O., Hussein, Waleed M., Skwarczynski, Mariusz and Toth, Istvan (2021). Key considerations for the development of safe and effective SARS‐CoV‐2 subunit vaccine: a peptide‐based vaccine alternative. Advanced Science, 8 (16) 2100985, 1-35. doi: 10.1002/advs.202100985 |
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2021 Journal Article Pre-clinical evaluation of a whole-parasite vaccine to control human babesiosisAl-Nazal, Hanan A., Cooper, Emily, Ho, Mei Fong, Eskandari, Sharareh, Majam, Victoria, Giddam, Ashwini Kumar, Hussein, Waleed M., Islam, Md Tanjir, Skwarczynski, Mariusz, Toth, Istvan, Kumar, Sanjai, Zaid, Ali, Batzloff, Michael, Stanisic, Danielle I. and Good, Michael F. (2021). Pre-clinical evaluation of a whole-parasite vaccine to control human babesiosis. Cell Host and Microbe, 29 (6), 894-903. doi: 10.1016/j.chom.2021.04.008 |
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2021 Journal Article Polyethylenimine quantity and molecular weight influence its adjuvanting properties in liposomal peptide vaccinesDai, Charles C., Huang, Wenbin, Yang, Jieru, Hussein, Waleed M., Wang, Jingwen, Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2021). Polyethylenimine quantity and molecular weight influence its adjuvanting properties in liposomal peptide vaccines. Bioorganic and Medicinal Chemistry Letters, 40 127920, 1-7. doi: 10.1016/j.bmcl.2021.127920 |
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2021 Journal Article Cell-penetrating peptides-based liposomal delivery system enhanced immunogenicity of peptide-based vaccine against group A streptococcusYang, Jieru, Firdaus, Farrhana, Azuar, Armira, Khalil, Zeinab G., Marasini, Nirmal, Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Cell-penetrating peptides-based liposomal delivery system enhanced immunogenicity of peptide-based vaccine against group A streptococcus. Vaccines, 9 (5) 499, 499. doi: 10.3390/vaccines9050499 |
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2021 Journal Article Discovery of a pyrimidine-dione derivative with potent inhibitory activity against Mycobacterium tuberculosis ketol-acid reductoisomeraseLin, Xin, Kurz, Julia, Patel, Khushboo, Wun, Shun Jie, Hussein, Waleed, Lonhienne, Thierry, West, Nicholas P., McGeary, Ross P., Schenk, Gerhard and Guddat, Luke William (2021). Discovery of a pyrimidine-dione derivative with potent inhibitory activity against Mycobacterium tuberculosis ketol-acid reductoisomerase. Chemistry: A European Journal, 27 (9) chem.202004665, 3130-3141. doi: 10.1002/chem.202004665 |
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2021 Journal Article Immunogenicity assessment of cell wall carbohydrates of Group A Streptococcus via self-adjuvanted glyco-lipopeptidesKhatun, Farjana, Dai, Charles C., Rivera-Hernandez, Tania, Hussein, Waleed M., Khalil, Zeinab G., Capon, Robert J., Toth, Istvan and Stephenson, Rachel J. (2021). Immunogenicity assessment of cell wall carbohydrates of Group A Streptococcus via self-adjuvanted glyco-lipopeptides. ACS Infectious Diseases, 7 (2) acsinfecdis.0c00722, 390-405. doi: 10.1021/acsinfecdis.0c00722 |
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2021 Journal Article Poly(hydrophobic amino acid)-based self-adjuvanting nanoparticles for Group A Streptococcus vaccine deliveryAzuar, Armira, Li, Zhuoqing, Shibu, Mohini A., Zhao, Lili, Luo, Yacheng, Shalash, Ahmed O., Khalil, Zeinab G., Capon, Robert J., Hussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Poly(hydrophobic amino acid)-based self-adjuvanting nanoparticles for Group A Streptococcus vaccine delivery. Journal of Medicinal Chemistry, 64 (5) acs.jmedchem.0c01660, 2648-2658. doi: 10.1021/acs.jmedchem.0c01660 |
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2021 Journal Article Analogues of the herbicide, N-hydroxy-N-isopropyloxamate, inhibit Mycobacterium tuberculosis ketol-acid reductoisomerase and their prodrugs are promising anti-TB drug leadsKandale, Ajit, Patel, Khushboo, Hussein, Waleed M., Wun, Shun Jie, Zheng, Shan, Tan, Lendl, West, Nicholas P., Schenk, Gerhard, Guddat, Luke W. and McGeary, Ross P. (2021). Analogues of the herbicide, N-hydroxy-N-isopropyloxamate, inhibit Mycobacterium tuberculosis ketol-acid reductoisomerase and their prodrugs are promising anti-TB drug leads. Journal of Medicinal Chemistry, 64 (3) acs.jmedchem.0c01919, 1670-1684. doi: 10.1021/acs.jmedchem.0c01919 |
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2021 Book Chapter Peptide-Polymer Conjugation Via Copper-Catalyzed Alkyne-Azide 1,3-Dipolar CycloadditionHussein, Waleed M., Toth, Istvan and Skwarczynski, Mariusz (2021). Peptide-Polymer Conjugation Via Copper-Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition. Methods in Molecular Biology. (pp. 1-7) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-1617-8_1 |
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2021 Book Chapter PrefaceHussein, Waleed H., Stephenson, Rachel J. and Toth, Istvan (2021). Preface. Peptide conjugation: methods and protocols. (pp. v-v) New York, NY USA: Humana Press. |
