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2023

Journal Article

Biogas upgrading using Clostridium autoethanogenum for value-added products

Heffernan, James K., Lai, Chun-Yu, Gonzalez-Garcia, R. Axayacatl, Nielsen, Lars Keld, Guo, Jianhua and Marcellin, Esteban (2023). Biogas upgrading using Clostridium autoethanogenum for value-added products. Chemical Engineering Journal, 452 (Part 1) 138950, 1-7. doi: 10.1016/j.cej.2022.138950

Biogas upgrading using Clostridium autoethanogenum for value-added products

2022

Journal Article

Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease

Lee, Richard G., Balasubramaniam, Shanti, Stentenbach, Maike, Kralj, Tom, McCubbin, Tim, Padman, Benjamin, Smith, Janine, Riley, Lisa G., Priyadarshi, Archana, Peng, Liuyu, Nuske, Madison R., Webster, Richard, Peacock, Ken, Roberts, Philip, Stark, Zornitza, Lemire, Gabrielle, Ito, Yoko A., Boycott, Kym M., Geraghty, Michael T., Klinken, Jan Bert, Ferdinandusse, Sacha, Zhou, Ying, Walsh, Rebecca, Marcellin, Esteban, Thorburn, David R., Rosciolli, Tony, Fletcher, Janice, Rackham, Oliver, Vaz, Frédéric M. ... Care4Rare Canada Consortium (2022). Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease. Human Molecular Genetics, 31 (21), 3597-3612. doi: 10.1093/hmg/ddac040

Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease

2022

Journal Article

Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing

Gunter, Helen M., Youlten, Scott E., Madala, Bindu Swapna, Reis, Andre L. M., Stevanovski, Igor, Wong, Ted, Kummerfield, Sarah K., Deveson, Ira W., Santini, Nadia S., Marcellin, Esteban and Mercer, Tim R. (2022). Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing. Nature Communications, 13 (1) 6437, 1-11. doi: 10.1038/s41467-022-34028-8

Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing

2022

Journal Article

RNA-seq sample preparation kits strongly affect transcriptome profiles of a gas-fermenting bacterium

de Lima, Lorena Azevedo, Reinmets, Kristina, Nielsen, Lars Keld, Marcellin, Esteban, Harris, Audrey, Köpke, Michael and Valgepea, Kaspar (2022). RNA-seq sample preparation kits strongly affect transcriptome profiles of a gas-fermenting bacterium. Microbiology Spectrum, 10 (4), 1-7. doi: 10.1128/spectrum.02303-22

RNA-seq sample preparation kits strongly affect transcriptome profiles of a gas-fermenting bacterium

2022

Journal Article

Knockout of Dicer-2 in the Sf9 cell line enhances the replication of Spodoptera frugiperda rhabdovirus and conditionally increases baculovirus replication

de Malmanche, Henry, Hussain, Mazhar, Marcellin, Esteban, Reid, Steve and Asgari, Sassan (2022). Knockout of Dicer-2 in the Sf9 cell line enhances the replication of Spodoptera frugiperda rhabdovirus and conditionally increases baculovirus replication. Journal of General Virology, 103 (8) 001779, 1-18. doi: 10.1099/jgv.0.001779

Knockout of Dicer-2 in the Sf9 cell line enhances the replication of Spodoptera frugiperda rhabdovirus and conditionally increases baculovirus replication

2022

Journal Article

Role of the substrate on Ni inhibition in biological sulfate reduction

Liu, Yun, Vaughan, James, Southam, Gordon, Serrano, Antonio, Gao, Han, Palfreyman, Robin, Marcellin, Esteban and Villa-Gomez, Denys K. (2022). Role of the substrate on Ni inhibition in biological sulfate reduction. Journal of Environmental Management, 316 115216, 115216. doi: 10.1016/j.jenvman.2022.115216

Role of the substrate on Ni inhibition in biological sulfate reduction

2022

Journal Article

Recycling carbon for sustainable protein production using gas fermentation

Marcellin, Esteban, Angenent, Largus T., Nielsen, Lars K. and Molitor, Bastian (2022). Recycling carbon for sustainable protein production using gas fermentation. Current Opinion in Biotechnology, 76 102723, 102723. doi: 10.1016/j.copbio.2022.102723

Recycling carbon for sustainable protein production using gas fermentation

2022

Journal Article

Engineering death resistance in CHO cells for improved perfusion culture

MacDonald, Michael A., Nöbel, Matthias, Martínez, Verónica S., Baker, Kym, Shave, Evan, Gray, Peter P., Mahler, Stephen, Munro, Trent, Nielsen, Lars K. and Marcellin, Esteban (2022). Engineering death resistance in CHO cells for improved perfusion culture. mAbs, 14 (1) e2083465, 1-13. doi: 10.1080/19420862.2022.2083465

Engineering death resistance in CHO cells for improved perfusion culture

2022

Journal Article

Analytical tools for unravelling the metabolism of gas-fermenting Clostridia

Heffernan, James K., Mahamkali, Vishnu, Valgepea, Kaspar, Marcellin, Esteban and Nielsen, Lars K. (2022). Analytical tools for unravelling the metabolism of gas-fermenting Clostridia. Current Opinion in Biotechnology, 75 102700, 102700. doi: 10.1016/j.copbio.2022.102700

Analytical tools for unravelling the metabolism of gas-fermenting Clostridia

2022

Journal Article

Response of the anaerobic methanotrophic archaeon candidatus “methanoperedens nitroreducens” to the long-term ferrihydrite amendment

Cai, Chen, Ni, Gaofeng, Xia, Jun, Zhang, Xueqin, Zheng, Yue, He, Bingqing, Marcellin, Esteban, Li, Weiwei, Pu, Jiaoyang, Yuan, Zhiguo and Hu, Shihu (2022). Response of the anaerobic methanotrophic archaeon candidatus “methanoperedens nitroreducens” to the long-term ferrihydrite amendment. Frontiers in Microbiology, 13 799859, 799859. doi: 10.3389/fmicb.2022.799859

Response of the anaerobic methanotrophic archaeon candidatus “methanoperedens nitroreducens” to the long-term ferrihydrite amendment

2022

Journal Article

Recent advances in the production of recombinant factor IX: bioprocessing and cell engineering

Beauglehole, Aiden C, Roche Recinos, Dinora, Pegg, Cassandra L, Lee, Yih Yean, Turnbull, Victor, Herrmann, Susann, Marcellin, Esteban, Howard, Christopher B and Schulz, Benjamin L (2022). Recent advances in the production of recombinant factor IX: bioprocessing and cell engineering. Critical Reviews in Biotechnology, 43 (3), 1-19. doi: 10.1080/07388551.2022.2036691

Recent advances in the production of recombinant factor IX: bioprocessing and cell engineering

2022

Journal Article

Faster growth enhances low carbon fuel and chemical production through gas fermentation

de Lima, Lorena Azevedo, Ingelman, Henri, Brahmbhatt, Kush, Reinmets, Kristina, Barry, Craig, Harris, Audrey, Marcellin, Esteban, Köpke, Michael and Valgepea, Kaspar (2022). Faster growth enhances low carbon fuel and chemical production through gas fermentation. Frontiers in Bioengineering and Biotechnology, 10 879578. doi: 10.3389/fbioe.2022.879578

Faster growth enhances low carbon fuel and chemical production through gas fermentation

2022

Journal Article

Knockout of Sf‐Caspase‐1 generates apoptosis‐resistant Sf9 cell lines: implications for baculovirus expression

Malmanche, Henry, Marcellin, Esteban and Reid, Steven (2022). Knockout of Sf‐Caspase‐1 generates apoptosis‐resistant Sf9 cell lines: implications for baculovirus expression. Biotechnology Journal, 17 (7) 2100532, 2100532. doi: 10.1002/biot.202100532

Knockout of Sf‐Caspase‐1 generates apoptosis‐resistant Sf9 cell lines: implications for baculovirus expression

2022

Journal Article

Absolute proteome quantification in the gas-fermenting acetogen Clostridium autoethanogenum

Valgepea, Kaspar, Talbo, Gert, Takemori, Nobuaki, Takemori, Ayako, Ludwig, Christina, Mahamkali, Vishnuvardhan, Mueller, Alexander P., Tappel, Ryan, Köpke, Michael, Simpson, Séan Dennis, Nielsen, Lars Keld and Marcellin, Esteban (2022). Absolute proteome quantification in the gas-fermenting acetogen Clostridium autoethanogenum. mSystems, 7 (2), 1. doi: 10.1128/msystems.00026-22

Absolute proteome quantification in the gas-fermenting acetogen Clostridium autoethanogenum

2022

Journal Article

A genome-scale metabolic model of Methanoperedens nitroreducens: assessing bioenergetics and thermodynamic feasibility

He, Bingqing, Cai, Chen, McCubbin, Tim, Muriel, Jorge Carrasco, Sonnenschein, Nikolaus, Hu, Shihu, Yuan, Zhiguo and Marcellin, Esteban (2022). A genome-scale metabolic model of Methanoperedens nitroreducens: assessing bioenergetics and thermodynamic feasibility. Metabolites, 12 (4) 314, 314. doi: 10.3390/metabo12040314

A genome-scale metabolic model of Methanoperedens nitroreducens: assessing bioenergetics and thermodynamic feasibility

2022

Journal Article

Modelling apoptosis resistance in CHO cells with CRISPR‐mediated knock‐outs of Bak1, Bax, and Bok

MacDonald, Michael A., Barry, Craig, Groves, Teddy, Martínez, Verónica S., Gray, Peter P., Baker, Kym, Shave, Evan, Mahler, Stephen, Munro, Trent, Marcellin, Esteban and Nielsen, Lars K. (2022). Modelling apoptosis resistance in CHO cells with CRISPR‐mediated knock‐outs of Bak1, Bax, and Bok. Biotechnology and Bioengineering, 119 (6), 1380-1391. doi: 10.1002/bit.28062

Modelling apoptosis resistance in CHO cells with CRISPR‐mediated knock‐outs of Bak1, Bax, and Bok

2022

Journal Article

Multi-omic characterisation of Streptomyces hygroscopicus NRRL 30439: detailed assessment of its secondary metabolic potential

Barry, Craig P., Gillane, Rosemary, Talbo, Gert H., Plan, Manual, Palfreyman, Robin, Haber-Stuk, Andrea K., Power, John, Nielsen, Lars K. and Marcellin, Esteban (2022). Multi-omic characterisation of Streptomyces hygroscopicus NRRL 30439: detailed assessment of its secondary metabolic potential. Molecular Omics, 18 (3), 226-236. doi: 10.1039/d1mo00150g

Multi-omic characterisation of Streptomyces hygroscopicus NRRL 30439: detailed assessment of its secondary metabolic potential

2022

Journal Article

Advances in systems metabolic engineering of autotrophic carbon oxide-fixing biocatalysts towards a circular economy

Pavan, Marilene, Reinmets, Kristina, Garg, Shivani, Mueller, Alexander P., Marcellin, Esteban, Köpke, Michael and Valgepea, Kaspar (2022). Advances in systems metabolic engineering of autotrophic carbon oxide-fixing biocatalysts towards a circular economy. Metabolic Engineering, 71, 117-141. doi: 10.1016/j.ymben.2022.01.015

Advances in systems metabolic engineering of autotrophic carbon oxide-fixing biocatalysts towards a circular economy

2021

Journal Article

High methanol‐to‐formate ratios induce butanol production in Eubacterium limosum

Wood, Jamin C., Marcellin, Esteban, Plan, Manuel R. and Virdis, Bernardino (2021). High methanol‐to‐formate ratios induce butanol production in Eubacterium limosum. Microbial Biotechnology, 15 (5), 1542-1549. doi: 10.1111/1751-7915.13963

High methanol‐to‐formate ratios induce butanol production in Eubacterium limosum

2021

Journal Article

Strategies to improve viability of a circular carbon bioeconomy – A techno-economic review of microbial electrosynthesis and gas fermentation

Wood, Jamin C., Grové, Johannes, Marcellin, Esteban, Heffernan, James K., Hu, Shihu, Yuan, Zhiguo and Virdis, Bernardino (2021). Strategies to improve viability of a circular carbon bioeconomy – A techno-economic review of microbial electrosynthesis and gas fermentation. Water Research, 201 117306, 1-14. doi: 10.1016/j.watres.2021.117306

Strategies to improve viability of a circular carbon bioeconomy – A techno-economic review of microbial electrosynthesis and gas fermentation