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2020

Conference Publication

Determinants of Therapeutic Lag in Relapsing Multiple Sclerosis

Roos, I., Frascoli, F., Horakova, D., Havrdova, E. Kubala, Trojano, M., Izquierdo, G., Eichau, S., Patti, F., Prat, A., Girard, M., Duquette, P., Onofrj, M., Lugaresi, A., Grammond, P., Ozakbas, S., Sola, P., Ferraro, D., Bergamaschi, R., Cartechini, E., Sa, M. Jose, Boz, C., Grand'Maison, F., Lechner-Scott, J., Terzi, M., Granella, F., Alroughani, R., Iuliano, G., Hupperts, R., Spitaleri, D. ... Kalincik, T. (2020). Determinants of Therapeutic Lag in Relapsing Multiple Sclerosis. Conference of MS Research Australia, Melbourne, Australia, 31 October-1 November 2019. London, United Kingdom: Sage Publications.

Determinants of Therapeutic Lag in Relapsing Multiple Sclerosis

2020

Conference Publication

Low dose Rituximab in the treatment of myasthenia gravis

Chan, Fiona, Swayne, Andrew, Gillis, David, Wong, Richard, Walsh, Michael, Henderson, Robert, McCombe, Pamela and Blum, Stefan (2020). Low dose Rituximab in the treatment of myasthenia gravis. 18th Biennial Clinical Neurophysiology Workshop of the Australian and New Zealand Association of Neurologists, Gold Coast, QLD, Australia, 29 September–2 October 2019. E Park, Shannon, Ireland: Elsevier . doi: 10.1016/j.clinph.2019.11.034

Low dose Rituximab in the treatment of myasthenia gravis

2020

Conference Publication

Clinical experience with cladribine in patients with relapsing-remitting multiple sclerosis

Hodgkinson, S., Lizak, N., Butler, E., Lechner-Scott, J., Slee, M., McCombe, P., Shaw, C., Skibina, O., Vucic, S., Shuey, N., Barnett, M., Parratt, J., Butzkueven, H., Jack, D., Fabris, J., Kalincik, T. and Jokubaitis, V. G. (2020). Clinical experience with cladribine in patients with relapsing-remitting multiple sclerosis. Conference of the Pan-Asian-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (PACTRIMS), Singapore, Singapore, 13-15 November 2019. London, United Kingdom: Sage.

Clinical experience with cladribine in patients with relapsing-remitting multiple sclerosis

2020

Conference Publication

Alemtuzumab Improves Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in RRMS Patients Over 8 Years: CARE-MS I Follow-up (TOPAZ Study)

Hartung, H-P, Comi, G., Arnold, D. L., Boyko, A. N., Havrdova, E. K., Inshasi, J. S., McCombe, P., Nakamura, K., Oreja-Guevara, C., Pelletier, D., Pozzilli, C., Selmaj, K. W., Scott, T. F., Chung, L., Daizadeh, N., Afsar, S. and Van Wijmeersch, B. (2020). Alemtuzumab Improves Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in RRMS Patients Over 8 Years: CARE-MS I Follow-up (TOPAZ Study). In: Conference of the Pan Asian Committee for Treatment and Research in Multiple Sclerosis (PACTRIMS), Singapore, Singapore, (NP60-NP61). 13-15 November 2019.

Alemtuzumab Improves Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in RRMS Patients Over 8 Years: CARE-MS I Follow-up (TOPAZ Study)

2020

Conference Publication

Postpartum Relapse After First On-Study Pregnancy in RRMS Patients Treated With Alemtuzumab in the Phase 2 and 3 Clinical Development Program Over 8 Years

Celius, Elisabeth G., Oh, Jiwon, Achiron, Anat, Compston, D. Alastair S., Devonshire, Virginia, Hellwig, Kerstin, Hutton, George J., McCombe, Pamela, Moore, Marie, Simm, Renata Faria, Sousa, Livia, Vincent, Stephen G., Chung, Luke, Daizadeh, Nadia, Mitchell, Colin and Rog, David (2020). Postpartum Relapse After First On-Study Pregnancy in RRMS Patients Treated With Alemtuzumab in the Phase 2 and 3 Clinical Development Program Over 8 Years. Annual Meeting of the American Academy of Neurology, Toronto, Canada, 25 April - 1 May 2020. Philadelphia, PA United States: Lippincott Williams & Wilkins.

Postpartum Relapse After First On-Study Pregnancy in RRMS Patients Treated With Alemtuzumab in the Phase 2 and 3 Clinical Development Program Over 8 Years

2020

Conference Publication

Efficacy Outcomes in RRMS Patients Who Switched From SC IFNB-1a in CARE-MS I and II to Alemtuzumab in the Extension Studies: 7-Year Follow-up

Pelletier, D., Arnold, D. L., Bass, A. D., Boyko, A. N., Broadley, S., Comi, G., McCombe, P., Montalban, X., Pozzilli, C., Rovira, A., Selmaj, K. W., Singer, B. A., Vermersch, P., Chung, L., Poole, E. and Wray, S. (2020). Efficacy Outcomes in RRMS Patients Who Switched From SC IFNB-1a in CARE-MS I and II to Alemtuzumab in the Extension Studies: 7-Year Follow-up. Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum, West Palm Beach, FL, United States, 27-29 February 2020. London, United Kingdom: Sage Publications.

Efficacy Outcomes in RRMS Patients Who Switched From SC IFNB-1a in CARE-MS I and II to Alemtuzumab in the Extension Studies: 7-Year Follow-up

2020

Conference Publication

Cladribine: a multicentre Long-term efficacy Biomarker Australian Study (CLOBAS)

L-Scott, J., Maltby, V., Lydon, A., Monif, M., Kilpatrick, T., Butzkueven, H., Taylor, B., McCombe, P., Hodgkinson, S., Fabis-Pedrini, M., Kermode, A., Barnett, M. and Kalincik, Tomas (2020). Cladribine: a multicentre Long-term efficacy Biomarker Australian Study (CLOBAS). Conference of the Pan Asian Committee for Treatment and Research in Multiple Sclerosis (PACTRIMS), Singapore, Singapore, 13-15 November 2019. London, United Kingdom: Sage.

Cladribine: a multicentre Long-term efficacy Biomarker Australian Study (CLOBAS)

2019

Conference Publication

Comparative effectiveness of natalizumab and fingolimod in different subgroups of patients with relapsing-remitting multiple sclerosis

Sharmin, S., Lefort, M., Andersen, J., Horakova, D., Havrdova, E. K., Alroughani, R., Izquierdo, G., Eichau, S., Ozakbas, S., Butzkueven, H., Patti, F., Onofrj, M., Lugaresi, A., Terzi, M., Grammond, P., Grand'Maison, F., Yamout, B., Prat, A., Girard, M., Duquette, P., Boz, C., Trojano, M., McCombe, P., Slee, M., Lechner-Scott, J., Turkoglu, R., Sola, P., Ferraro, D., Granella, F. ... Kalincik, T. (2019). Comparative effectiveness of natalizumab and fingolimod in different subgroups of patients with relapsing-remitting multiple sclerosis. 35th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm Sweden, Sep 11-13, 2019. LONDON: SAGE PUBLICATIONS LTD.

Comparative effectiveness of natalizumab and fingolimod in different subgroups of patients with relapsing-remitting multiple sclerosis

2019

Conference Publication

Personalizing treatment effect based on patient's baseline profile: a statistical modelling approach applied to randomized clinical trial and observational study data

Bovis, F., Kalincik, T., Lublin, F., Cutter, G., Malpas, C., Horakova, D., Havrdova, E. Kubala, Trojano, M., Prat, A., Girard, M., Duquette, P., Onofrj, M., Lugaresi, A., Izquierdo, G., Eichau, S., Patti, F., Terzi, M., Grammond, P., Bergamaschi, R., Sola, P., Ferraro, D., Ozakbas, S., Iuliano, G., Boz, C., Hupperts, R., Grand'Maison, F., Oreja-Guevara, C., Van Pesch, V., Cartechini, E. ... Sormani, M. P. (2019). Personalizing treatment effect based on patient's baseline profile: a statistical modelling approach applied to randomized clinical trial and observational study data. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications.

Personalizing treatment effect based on patient's baseline profile: a statistical modelling approach applied to randomized clinical trial and observational study data

2019

Conference Publication

Modifiers of the effectiveness of MS immunotherapies

Kalincik, T., Malpas, C., Sharmin, S., Horakova, D., Havrdova, E. K., Trojano, M., Izquierdo, G., Eichau, S., Onofrj, M., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Grammond, P., Grand'Maison, F., Sola, P., Ferraro, D., Shaygannejad, V., Alroughani, R., Hupperts, R., Terzi, M., Boz, C., Lechner-Scott, J., Cartechini, E., Van Pesch, V., Iuliano, G., Granella, F., Bergamaschi, R., Bolanos, R. F. ... Butzkueven, H. (2019). Modifiers of the effectiveness of MS immunotherapies. 35th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm Sweden, Sep 11-13, 2019. LONDON: SAGE PUBLICATIONS LTD.

Modifiers of the effectiveness of MS immunotherapies

2019

Conference Publication

Predicting long-term sustained disability progression in multiple sclerosis

Sharmin, S., Malpas, C., Horakova, D., Havrdova, E. K., Izquierdo, G., Eichau, S., Trojano, M., Prat, A., Girard, M., Duquette, P., Onofrj, M., Lugaresi, A., Grand'Maison, F., Grammond, P., Sola, P., Ferraro, D., Terzi, M., Hupperts, R., Alroughani, R., Boz, C., Shaygannejad, V., Van Pesch, V., Cartechini, E., Kappos, L., Lechner-Scott, J., Bergamaschi, R., Turkoglu, R., Solaro, C., Ramo-Tello, C. ... Kalincik, T. (2019). Predicting long-term sustained disability progression in multiple sclerosis. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications.

Predicting long-term sustained disability progression in multiple sclerosis

2019

Conference Publication

Introducing Machine Learning for full MS patient trajectories improves predictions for disability score progression

De Brouwer, E., Peeters, L., Becker, T., Altintas, A., Soysal, A., Van Wijmeersch, B., Boz, C., Oreja-Guevara, C., Gobbi, C., Solaro, C., Ramo, C., Spitaleri, D. L., Maimone, D., Aguera-Morales, E., Cartechini, E., Butler, E., Havrdova, E., Patti, F., Granella, F., Grand'Maison, F., Moore, F., Verheul, F., Iuliano, G., Butzkueven, H., Lechner-Scott, J., Kuhle, J., Sanchez Menoyo, J. L., Rojas, J. I., Prevost, J. ... Moreau, Y. (2019). Introducing Machine Learning for full MS patient trajectories improves predictions for disability score progression. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications.

Introducing Machine Learning for full MS patient trajectories improves predictions for disability score progression

2019

Conference Publication

Determinants of therapeutic lag in relapsing multiple sclerosis

Roos, I., Frascoli, F., Horakova, D., Havrdova, E. K., Trojano, M., Izquierdo, G., Eichau, S., Patti, F., Prat, A., Girard, M., Duquette, P., Onofr, M., Lugaresi, A., Grammond, P., Ozakbas, S., Sola, P., Ferraro, D., Bergamaschi, R., Cartechini, E., Sa, M. J., Boz, C., Grand'Maison, F., Lechner-Scott, J., Terzi, M., Granella, F., Alroughani, R., Iuliano, G., Hupperts, R., Spitaleri, D. ... Kalincik, T. (2019). Determinants of therapeutic lag in relapsing multiple sclerosis. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications.

Determinants of therapeutic lag in relapsing multiple sclerosis

2019

Conference Publication

Aggressive form of multiple sclerosis can be predicted early after disease onset

Malpas, C. B., Manouchehrinia, A., Sharmin, S., Roos, I., Horakova, D., Havrdova, E. K., Trojano, M., Izquierdo, G., Eichau, S., Bergamaschi, R., Sola, P., Ferraro, D., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Grammond, P., Grand'Maison, F., Ozakbas, S., Van Pesch, V., Granella, F., Hupperts, R., Pucci, E., Boz, C., Iuliano, G., Sidhom, Y., Gouider, R., Spitaleri, D., Butzkueven, H. ... Kalincik, T. (2019). Aggressive form of multiple sclerosis can be predicted early after disease onset. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications.

Aggressive form of multiple sclerosis can be predicted early after disease onset

2019

Conference Publication

Alemtuzumab improves clinical and MRI outcomes, including slowing of brain volume loss, in RRMS patients over 8 years: CARE-MS I follow-up (TOPAZ Study)

Comi, G., Arnold, D. L., Boyko, A. N., Hartung, H. -P., Havrdova, E. K., Inshasi, J. S., McCombe, P., Nakamura, K., Oreja-Guevara, C., Pelletier, D., Pozzilli, C., Selmaj, K. W., Scott, T. F., Chung, L., Daizadeh, N., Afsar, S. and Van Wijmeersch, B. (2019). Alemtuzumab improves clinical and MRI outcomes, including slowing of brain volume loss, in RRMS patients over 8 years: CARE-MS I follow-up (TOPAZ Study). 5th Congress of the European-Academy-of-Neurology (EAN), Oslo Norway, Jun 29-Jul 02, 2019. HOBOKEN: WILEY.

Alemtuzumab improves clinical and MRI outcomes, including slowing of brain volume loss, in RRMS patients over 8 years: CARE-MS I follow-up (TOPAZ Study)

2019

Conference Publication

Investigating the effect of teriflunomide on diffuse cortical grey matter volume loss in the phase 3 TOPIC study

Sprenger, T., Lebrun-Frenay, C., Vermersch, P., Park, M. S., Chinchilla, D., McCombe, P., Lincoln, J., Bergsland, N., Dwyer, M., Kappos, L., Cavalier, S., Roesch, N., Guce, M., Poole, E. and Zivadinov, R. (2019). Investigating the effect of teriflunomide on diffuse cortical grey matter volume loss in the phase 3 TOPIC study. 5th Congress of the European-Academy-of-Neurology (EAN), Oslo Norway, Jun 29-Jul 02, 2019. HOBOKEN: WILEY.

Investigating the effect of teriflunomide on diffuse cortical grey matter volume loss in the phase 3 TOPIC study

2019

Conference Publication

Improved Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in Alemtuzumab-Treated RRMS Patients: 8-Year Follow-up of CARE-MS I (TOPAZ Study)

Pelletier, Daniel, Arnold, Douglas L., Boyko, Alexey N., Comi, Giancarlo, Hartung, Hans-Peter, Havrdova, Eva Kubala, Inshasi, Jihad Said, McCombe, Pamela, Nakamura, Kunio, Oreja-Guevara, Celia, Pozzilli, Carlo, Selmaj, Krzysztof W., Scott, Thomas F., Chung, Luke, Daizadeh, Nadia, Afsar, Salman and Van Wijmeersch, Bart (2019). Improved Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in Alemtuzumab-Treated RRMS Patients: 8-Year Follow-up of CARE-MS I (TOPAZ Study). 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia Pa, May 04-10, 2019. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Improved Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in Alemtuzumab-Treated RRMS Patients: 8-Year Follow-up of CARE-MS I (TOPAZ Study)

2019

Conference Publication

Improved Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in Alemtuzumab-Treated RRMS Patients: 8-Year Follow-up of CARE-MS I (TOPAZ Study)

Pelletier, Daniel, Arnold, Douglas L., Boyko, Alexey N., Comi, Giancarlo, Hartung, Hans-Peter, Havrdova, Eva Kubala, Inshasi, Jihad Said, McCombe, Pamela, Nakamura, Kunio, Oreja-Guevara, Celia, Pozzilli, Carlo, Selmaj, Krzysztof W., Scott, Thomas F., Chung, Luke, Daizadeh, Nadia, Afsar, Salman and Van Wijmeersch, Bart (2019). Improved Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in Alemtuzumab-Treated RRMS Patients: 8-Year Follow-up of CARE-MS I (TOPAZ Study). AAN 71st Annual Meeting, Philadelphia, PA United States, 4-10 May 2019. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.92.15_supplement.p3.2-037

Improved Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in Alemtuzumab-Treated RRMS Patients: 8-Year Follow-up of CARE-MS I (TOPAZ Study)

2019

Conference Publication

Clinical determinants and therapeutic modifiers of relapse and disability outcomes in neuromyelitis optica spectrum disorder

Kunchok, Amy, Malpas, Charles, Nytrova, Petra, Havrdova, Eva, Alroughani, Raed, Terzi, Murat, Yamout, Bassem, Hor, Jyh Yung, Karabudak, Rana, Boz, Cavit, Ozakbas, Serkan, Olascoaga Urtaza, Francisco Javier, Simo, Magdolna, Granella, Franco, Patti, Francesco, McCombe, Pamela, Csepany, Tunde, Singhal, Bhim, Bergamaschi, Roberto, Fragoso, Yara, Al-Harbi, Talal, Turkoglu, Recai, Lechner-Scott, Jeannette, Laureys, Guy, Oreja-Guevara, Celia, Pucci, Eugenio, Sola, Patrizia, Ferraro, Diana, Altintas, Ayse ... Kalincik, Tomas (2019). Clinical determinants and therapeutic modifiers of relapse and disability outcomes in neuromyelitis optica spectrum disorder. 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia, PA, United States, 4-10 May 2019. Philadelphia, PA, United States: Wolters Kluwer Health.

Clinical determinants and therapeutic modifiers of relapse and disability outcomes in neuromyelitis optica spectrum disorder

2019

Conference Publication

Investigating the Effect of Teriflunomide on Brain Volume Loss in the Phase 3 TOPIC Study

Sprenger, Till, Lebrun-Frenay, Christine, Vermersch, Patrick, Park, Min Su, Chinchilla, Dennis, McCombe, Pamela, Lincoln, John, Kappos, Ludwig, Bergsland, Niels, Dwyer, Michael, Cavalier, Steven, Roesch, Nora, Somera-Molina, Kathleen, Poole, Elizabeth and Zivadinov, Robert (2019). Investigating the Effect of Teriflunomide on Brain Volume Loss in the Phase 3 TOPIC Study. 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia Pa, May 04-10, 2019. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Investigating the Effect of Teriflunomide on Brain Volume Loss in the Phase 3 TOPIC Study