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2024 Journal Article A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissueShanmugasundaram, Karthik B., Ahmed, Emtiaz, Miao, Xinzhe, Kulasinghe, Arutha, Fletcher, James A., Monkman, James, Mainwaring, Paul, Masud, Mostafa Kamal, Park, Hyeongyu, Hossain, Md Shahriar A., Yamauchi, Yusuke, Sina, Abu A. I., O’Byrne, Kenneth, Wuethrich, Alain and Trau, Matt (2024). A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue. ACS Sensors, 9 (6), 3009-3016. doi: 10.1021/acssensors.4c00192 |
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2024 Journal Article Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profilesNiu, Xueming, Zhang, Zhen, Zhou, Quan, Wuethrich, Alain, Lobb, Richard and Trau, Matt (2024). Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profiles. Proteomics, 24 (11) 2300094, e2300094. doi: 10.1002/pmic.202300094 |
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2024 Journal Article Molecular Stratification and Treatment Monitoring of Lung Cancer Using a Small Extracellular Vesicle-Activated Nanocavity ArchitectureLi, Junrong, Li, Meiqin, Wuethrich, Alain, Guan, Rui, Zhao, Lihui, Hu, Cong, Trau, Matt and Sun, Yao (2024). Molecular Stratification and Treatment Monitoring of Lung Cancer Using a Small Extracellular Vesicle-Activated Nanocavity Architecture. Analytical Chemistry, 96 (19), 7651-7660. doi: 10.1021/acs.analchem.4c00558 |
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2024 Journal Article High Accuracy of Clinical Verification of Electrohydrodynamic-Driven Nanobox-on-Mirror Platform for Molecular Identification of Respiratory VirusesLi, Junrong, Guan, Rui, Wuethrich, Alain, Yan, Mingzhe, Cheng, Jing, Liu, Guorong, Zhan, Jianbo, Trau, Matt and Sun, Yao (2024). High Accuracy of Clinical Verification of Electrohydrodynamic-Driven Nanobox-on-Mirror Platform for Molecular Identification of Respiratory Viruses. Analytical Chemistry, 96 (11), 4495-4504. doi: 10.1021/acs.analchem.3c05120 |
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2024 Journal Article Special issue Methods: Nano-/bio-interface and biomedical applicationsLi, Li and Wuethrich, Alain (2024). Special issue Methods: Nano-/bio-interface and biomedical applications. Methods, 223, 146-147. doi: 10.1016/j.ymeth.2024.02.001 |
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2024 Journal Article Digital platforms enabling single-molecule analysis for cancer detectionLi, Junrong, Zhang, Zhen, Trau, Matt and Wuethrich, Alain (2024). Digital platforms enabling single-molecule analysis for cancer detection. TrAC Trends in Analytical Chemistry, 171 117502, 117502. doi: 10.1016/j.trac.2023.117502 |
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2024 Journal Article Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypesZhou, Quan, Wang, Jing, Zhang, Zhen, Wuethrich, Alain, Lobb, Richard J. and Trau, Matt (2024). Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes. Biosensors and Bioelectronics, 244 115819, 1-10. doi: 10.1016/j.bios.2023.115819 |
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2024 Journal Article A perspective about the potential use of nanotechnology to monitor immune correlates of the clinical course of major mood disordersWuethrich, Alain, Crouse, Jacob J., Vedelago, Courtney, Zhang, Yiwen, Farokhinejad, Fahimeh, Hickie, Ian B. and Trau, Matt (2024). A perspective about the potential use of nanotechnology to monitor immune correlates of the clinical course of major mood disorders. Research Directions: Depression, 1 e20. doi: 10.1017/dep.2024.3 |
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2024 Journal Article Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancerZhou, Quan, Niu, Xueming, Zhang, Zhen, O'Byrne, Kenneth, Kulasinghe, Arutha, Fielding, David, Möller, Andreas, Wuethrich, Alain, Lobb, Richard J. and Trau, Matt (2024). Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancer. Advanced Science, 11 (33) 2401818, e2401818. doi: 10.1002/advs.202401818 |
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2023 Journal Article Multiplex SERS-lectin-immunoassay for esophageal adenocarcinoma screeningKhamis, Ramlah, Shanmugasundaram, Karthik B., Zhou, Quan, Lu, Jennifer, Zhang, Zhen, Hill, Michelle M., Sina, Abu Ali Ibn, Trau, Matt and Wuethrich, Alain (2023). Multiplex SERS-lectin-immunoassay for esophageal adenocarcinoma screening. ACS Applied Nano Materials, 6 (21), 20190-20197. doi: 10.1021/acsanm.3c03987 |
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2023 Journal Article Erratum: Correction: Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung diseases (Nanoscale horizons (2023) 8 6 (746-758))Yuan, Liwen, Chen, Yanpin, Ke, Longfeng, Zhou, Quan, Chen, Jiayou, Fan, Min, Wuethrich, Alain, Trau, Matt and Wang, Jing (2023). Erratum: Correction: Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung diseases (Nanoscale horizons (2023) 8 6 (746-758)). Nanoscale horizons, 8 (9), 1288-1289. doi: 10.1039/d3nh90028b |
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2023 Journal Article A microfluidic liquid biopsy platform to monitor protein biomarker heterogeneity in single circulating therapy‐resistance cancer cellAhmed, Emtiaz, Shanmugasundaram, Karthik Balaji, Li, Junrong, Behren, Andreas, Lobb, Richard, Möller, Andreas, Wuethrich, Alain, Dey, Shuvashis, Sina, Abu Ali Ibn and Trau, Matt (2023). A microfluidic liquid biopsy platform to monitor protein biomarker heterogeneity in single circulating therapy‐resistance cancer cell. Advanced Sensor Research, 2 (12) ARTN 2300059. doi: 10.1002/adsr.202300059 |
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2023 Journal Article A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragmentsLi, Junrong, Howard, Christopher B., Dey, Shuvashis, Lowry, Kym, Whiley, David M., Puttick, Simon, Rose, Stephen, Lobb, Richard J., Wuethrich, Alain, Edwardraja, Selvakumar and Trau, Matt (2023). A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragments. Nature Nanotechnology, 18 (10), 1222-1229. doi: 10.1038/s41565-023-01415-1 |
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2023 Journal Article Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung diseaseYuan, Liwen, Chen, Yanping, Ke, Longfeng, Zhou, Quan, Chen, Jiayou, Fan, Min, Wuethrich, Alain, Trau, Matt and Wang, Jing (2023). Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung disease. Nanoscale Horizons, 8 (6), 746-758. doi: 10.1039/d2nh00570k |
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2023 Journal Article Liquid biopsy snapshots of key phosphoproteomic pathways in lung cancer patients for diagnosis and therapy monitoringAhmed, Mostak, Wuethrich, Alain, Constantin, Nicolas, Shanmugasundaram, Karthik Balaji, Mainwaring, Paul, Kulasinghe, Arutha, O’Leary, Connor, O’Byrne, Ken, Sina, Abu Ali Ibn, Carrascosa, Laura G. and Trau, Matt (2023). Liquid biopsy snapshots of key phosphoproteomic pathways in lung cancer patients for diagnosis and therapy monitoring. Analytical Chemistry, 95 (22), 8522-8532. doi: 10.1021/acs.analchem.3c00519 |
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2023 Journal Article A multiplexed SERS microassay for accurate detection of SARS-CoV-2 and variants of concernVedelago, Courtney, Li, Junrong, Lowry, Kym, Howard, Christopher, Wuethrich, Alain and Trau, Matt (2023). A multiplexed SERS microassay for accurate detection of SARS-CoV-2 and variants of concern. ACS Sensors, 8 (4), 1648-1657. doi: 10.1021/acssensors.2c02782 |
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2023 Journal Article Nurturing the marriages of urinary liquid biopsies and nano‐diagnostics for precision urinalysis of prostate cancerLiao, Caizhi, Wu, Zhihao, Lin, Chan, Chen, Xiaofeng, Zou, Yaqun, Zhao, Wan, Li, Xin, Huang, Guangqi, Xu, Baisheng, Briganti, Giovanni E., Qi, Yan, Wang, Xianshu, Zeng, Tao, Wuethrich, Alain and Zou, Hongzhi (2023). Nurturing the marriages of urinary liquid biopsies and nano‐diagnostics for precision urinalysis of prostate cancer. Smart Medicine, 2 (1), 1-30. doi: 10.1002/smmd.20220020 |
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2023 Journal Article Digital decoding of single extracellular vesicle phenotype differentiates early malignant and benign lung lesionsLi, Junrong, Sina, Abu A. I., Antaw, Fiach, Fielding, David, Möller, Andreas, Lobb, Richard, Wuethrich, Alain and Trau, Matt (2023). Digital decoding of single extracellular vesicle phenotype differentiates early malignant and benign lung lesions. Advanced Science, 10 (1) 2204207, e2204207. doi: 10.1002/advs.202204207 |
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2023 Journal Article Status quo of extracellular vesicle isolation and detection methods for clinical utilityVisan, Kekoolani S., Wu, Li-Ying, Voss, Sarah, Wuethrich, Alain and Möller, Andreas (2023). Status quo of extracellular vesicle isolation and detection methods for clinical utility. Seminars in Cancer Biology, 88, 157-171. doi: 10.1016/j.semcancer.2022.12.008 |
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2022 Journal Article SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapyLi, Junrong, Wuethrich, Alain, Zhang, Zhen, Wang, Jing, Lin, Lynlee L., Behren, Andreas, Wang, Yuling and Trau, Matt (2022). SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy. Analytical Chemistry, 94 (42), 14573-14582. doi: 10.1021/acs.analchem.2c02398 |
