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2026 Journal Article Early-stage multi-cancer detection through a plasma extracellular vesicle protein signatureLobb, Richard J., Zhou, Quan, Fielding, David, Visan, Kekoolani S., Wuethrich, Alain, Wang, Jing, Hu, Youran, Norris, Emma L., Hastie, Marcus L., Everitt, Sarah, Parris, Brielle, Aoude, Lauren G., Bonazzi, Vanessa F., Nixon, Elizabeth, Mooi, Jennifer, Koo, Kevin M., O'Byrne, Kenneth, Kulasinghe, Arutha, Bowman, Rayleen V., Yang, Ian A., Corcoran, Niall M., Hovens, Christopher M., MacManus, Michael, Gorman, Jeffrey J., Day, Bryan W., Hartel, Gunter, Whiteman, David C., Tebbutt, Niall, Mariadason, John M. ... Möller, Andreas (2026). Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature. Cell Reports Medicine, 7 (4) 102694, 1-20. doi: 10.1016/j.xcrm.2026.102694 |
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2026 Journal Article Multifactor authentication in extracellular vesicle analysis: methods and approaches to address the heterogeneity problemZhou, Quan, Lobb, Richard J., Wuethrich, Alain and Trau, Matt (2026). Multifactor authentication in extracellular vesicle analysis: methods and approaches to address the heterogeneity problem. Nature Methods. doi: 10.1038/s41592-026-03068-z |
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2026 Journal Article Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetesCao, Yuanzhao, Redd, Meredith A., Outhwaite, Jennifer E., Mizikovsky, Dalia, Shim, Woo Jun, Fang, Chen, Vedelago, Courtney, Tan, Clarissa, Wu, Zhixuan, Daygon, Dara, Stark, Terra, Palfreyman, Robin, Chiu, Han Sheng, Thomas, Ulrich, Dragicevic, Elena, Sng, Julian D. J., Saez, Natalie J., Barrett, Helen L., Dorey, Emily S., King, Glenn F., Wuethrich, Alain, Trau, Matt, Shah, Sonia, Short, Kirsty R. and Palpant, Nathan J. (2026). Glycaemic variability underlies myocyte dysfunction and myocardial injury risk in diabetes. Nature Communications. doi: 10.1038/s41467-026-71809-x |
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2026 Journal Article Nanobiosensors and Artificial Intelligence Strategies for Glycan Profiling in Cancer Progression: A Critical ReviewKhamis, Ramlah, Wu, Yuao, Sina, Abu Ali Ibn, Trau, Matt and Wuethrich, Alain (2026). Nanobiosensors and Artificial Intelligence Strategies for Glycan Profiling in Cancer Progression: A Critical Review. ACS Sensors acssensors.5c04911. doi: 10.1021/acssensors.5c04911 |
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2026 Other Outputs Multi-omics dataset of TGF-β-induced EMT in breast cancerZhang, Zhen, Ahmed, Emtiaz, Constantin, Nicholas, Lu, Jennifer, Portelli, Stephanie, Ascher, David, Korbie, Darren, Wuethrich, Alain, Sina, Abu and Trau, Matt (2026). Multi-omics dataset of TGF-β-induced EMT in breast cancer. The University of Queensland. (Dataset) doi: 10.48610/954d1e6 |
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2026 Journal Article Programmable dual‐targeting nano bioconjugates: a universal bioconjugation strategy to enhance single molecule proteomic assaysFarokhinejad, Fahimeh, Anderson, Will, Niu, Xueming, Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2026). Programmable dual‐targeting nano bioconjugates: a universal bioconjugation strategy to enhance single molecule proteomic assays. Small Methods, 10 (7) e01235, 1-13. doi: 10.1002/smtd.202501235 |
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2025 Journal Article Ultrasensitive multiplex detection of lung cancer EV-associated immune checkpoints using a mesoporous gold enhanced SERS biosensorAhmed, Emtiaz, Masud, Mostafa Kamal, Wuethrich, Alain, Edwardraja, Selvakumar, Dey, Shuvashis, Hasan, Mahedi, Hossain, Md. Shahriar A., Yamauchi, Yusuke, Trau, Matt and Sina, Abu Ali Ibn (2025). Ultrasensitive multiplex detection of lung cancer EV-associated immune checkpoints using a mesoporous gold enhanced SERS biosensor. Nanoscale, 17 (48), 28143-28154. doi: 10.1039/d5nr03653d |
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2025 Journal Article A digital single‐molecule nanocavity assay to monitor phosphoprotein circuits in single‐cellMiao, Xinzhe, Shanmugasundaram, Karthik, Vedelago, Courtney, Naei, Vahid Yaghoubi, Kulasinghe, Arutha, Lobb, Richard, Trau, Matt and Wuethrich, Alain (2025). A digital single‐molecule nanocavity assay to monitor phosphoprotein circuits in single‐cell. Advanced Materials Technologies, 11 (7) e02611. doi: 10.1002/admt.202502611 |
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2025 Journal Article Single extracellular vesicle profiling to define brain specific traumatic brain injury induced neuro‐inflammationZhang, Zhen, Lobb, Richard J., Lane, Rebecca E., To, Xuan Vinh, Niu, Xueming, Antaw, Fiach, Pietrogrande, Giovanni, Winter, Craig, Wuethrich, Alain, Nasrallah, Fatima and Trau, Matt (2025). Single extracellular vesicle profiling to define brain specific traumatic brain injury induced neuro‐inflammation. Small Methods, 9 (7) 2401931, 1-9. doi: 10.1002/smtd.202401931 |
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2025 Journal Article Multiplex cardiac biomarker profiling for precision coronary artery disease risk assessment using SERS with cubic core–satellite nanostructuresZhang, Tuotuo, Li, Bin, Wuethrich, Alain, Liu, Huixing, Zhou, Quan, Hu, Zhuoran, Wang, Huiling, Trau, Matt, Bao, Feng, Li, Jian, Sun, Yao and Li, Junrong (2025). Multiplex cardiac biomarker profiling for precision coronary artery disease risk assessment using SERS with cubic core–satellite nanostructures. Analytical Chemistry, 97 (27), 14750-14760. doi: 10.1021/acs.analchem.5c02349 |
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2025 Journal Article Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoringZhang, Zhen, Wang, Jing, Wuethrich, Alain and Trau, Matt (2025). Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoring. National Science Review, 12 (3) nwae452, 1-17. doi: 10.1093/nsr/nwae452 |
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2024 Journal Article Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte functionSinclair, Jane E., Vedelago, Courtney, Ryan, Feargal J., Carney, Meagan, Redd, Meredith A., Lynn, Miriam A., Grubor-Bauk, Branka, Cao, Yuanzhao, Henders, Anjali K., Chew, Keng Yih, Gilroy, Deborah, Greaves, Kim, Labzin, Larisa, Ziser, Laura, Ronacher, Katharina, Wallace, Leanne M., Zhang, Yiwen, Macauslane, Kyle, Ellis, Daniel J., Rao, Sudha, Burr, Lucy, Bain, Amanda, Karawita, Anjana, Schulz, Benjamin L., Li, Junrong, Lynn, David J., Palpant, Nathan, Wuethrich, Alain, Trau, Matt and Short, Kirsty R. (2024). Post-acute sequelae of SARS-CoV-2 cardiovascular symptoms are associated with trace-level cytokines that affect cardiomyocyte function. Nature Microbiology, 9 (12), 1-13. doi: 10.1038/s41564-024-01838-z |
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2024 Journal Article Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancerZhou, Quan, Niu, Xueming, Zhang, Zhen, O'Byrne, Kenneth, Kulasinghe, Arutha, Fielding, David, Möller, Andreas, Wuethrich, Alain, Lobb, Richard J. and Trau, Matt (2024). Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancer. Advanced Science, 11 (33) 2401818, 1-12. doi: 10.1002/advs.202401818 |
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2024 Journal Article A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissueShanmugasundaram, Karthik B., Ahmed, Emtiaz, Miao, Xinzhe, Kulasinghe, Arutha, Fletcher, James A., Monkman, James, Mainwaring, Paul, Masud, Mostafa Kamal, Park, Hyeongyu, Hossain, Md Shahriar A., Yamauchi, Yusuke, Sina, Abu A. I., O’Byrne, Kenneth, Wuethrich, Alain and Trau, Matt (2024). A mesoporous gold sensor unveils phospho PD-L1 in extracellular vesicles as a proxy for PD-L1 expression in lung cancer tissue. ACS Sensors, 9 (6), 3009-3016. doi: 10.1021/acssensors.4c00192 |
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2024 Journal Article Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profilesNiu, Xueming, Zhang, Zhen, Zhou, Quan, Wuethrich, Alain, Lobb, Richard and Trau, Matt (2024). Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profiles. Proteomics, 24 (11) 2300094, 1-13. doi: 10.1002/pmic.202300094 |
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2024 Journal Article Molecular stratification and treatment monitoring of lung cancer using a small extracellular vesicle-activated nanocavity architectureLi, Junrong, Li, Meiqin, Wuethrich, Alain, Guan, Rui, Zhao, Lihui, Hu, Cong, Trau, Matt and Sun, Yao (2024). Molecular stratification and treatment monitoring of lung cancer using a small extracellular vesicle-activated nanocavity architecture. Analytical Chemistry, 96 (19), 7651-7660. doi: 10.1021/acs.analchem.4c00558 |
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2024 Journal Article High accuracy of clinical verification of electrohydrodynamic-driven nanobox-on-mirror platform for molecular identification of respiratory virusesLi, Junrong, Guan, Rui, Wuethrich, Alain, Yan, Mingzhe, Cheng, Jing, Liu, Guorong, Zhan, Jianbo, Trau, Matt and Sun, Yao (2024). High accuracy of clinical verification of electrohydrodynamic-driven nanobox-on-mirror platform for molecular identification of respiratory viruses. Analytical Chemistry, 96 (11), 4495-4504. doi: 10.1021/acs.analchem.3c05120 |
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2024 Journal Article Special issue Methods: Nano-/bio-interface and biomedical applicationsLi, Li and Wuethrich, Alain (2024). Special issue Methods: Nano-/bio-interface and biomedical applications. Methods, 223, 146-147. doi: 10.1016/j.ymeth.2024.02.001 |
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2024 Journal Article Digital platforms enabling single-molecule analysis for cancer detectionLi, Junrong, Zhang, Zhen, Trau, Matt and Wuethrich, Alain (2024). Digital platforms enabling single-molecule analysis for cancer detection. TrAC Trends in Analytical Chemistry, 171 117502, 1-12. doi: 10.1016/j.trac.2023.117502 |
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2024 Journal Article Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypesZhou, Quan, Wang, Jing, Zhang, Zhen, Wuethrich, Alain, Lobb, Richard J. and Trau, Matt (2024). Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes. Biosensors and Bioelectronics, 244 115819, 1-10. doi: 10.1016/j.bios.2023.115819 |
