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1999 Journal Article Cu(II) potentiation of Alzheimer A beta neurotoxicity - Correlation with cell-free hydrogen peroxide production and metal reductionHuang, XD, Cuajungco, MP, Atwood, CS, Hartshorn, MA, Tyndall, JDA, Hanson, GR, Stokes, KC, Leopold, M, Multhaup, G, Goldstein, LE, Scarpa, RC, Saunders, AJ, Lim, J, Moir, RD, Glabe, C, Bowden, EF, Masters, CL, Fairlie, DP, Tanzi, RE and Bush, AI (1999). Cu(II) potentiation of Alzheimer A beta neurotoxicity - Correlation with cell-free hydrogen peroxide production and metal reduction. Journal of Biological Chemistry, 274 (52), 37111-37116. doi: 10.1074/jbc.274.52.37111 |
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1999 Journal Article Homology model of the dengue 2 virus NS3 protease: putative interactions with both substrate and NS2B cofactor.Brinkworth, R. I., Fairlie, D., Leung, D. and Young, P. R. (1999). Homology model of the dengue 2 virus NS3 protease: putative interactions with both substrate and NS2B cofactor.. Journal of General Virology, 80 (5), 1167-1177. doi: 10.1099/0022-1317-80-5-1167 |
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1999 Journal Article Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the ratShort, Anna, Wong, Allan K., Finch, Angela M., Haaima, Gerald, Shiels, Ian A., Fairlie, David P. and Taylor, Stephen M. (1999). Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the rat. British Journal of Pharmacology, 126 (2), 551-554. doi: 10.1038/sj.bjp.0702338 |
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1999 Journal Article Pharmacological characterization of antagonists of the C5a receptorPaczkowski, NJ, Finch, AM, Whitmore, JB, Short, AJ, Wong, AK, Monk, PN, Cain, SA, Fairlie, DP and Taylor, SM (1999). Pharmacological characterization of antagonists of the C5a receptor. British Journal of Pharmacology, 128 (10), 1461-1466. doi: 10.1038/sj.bjp.0702938 |
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1999 Journal Article Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate.Qiu, L., Kelso, M., Hansen, C., West, M. L., Fairlie, D. and Parsons, P. (1999). Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate.. British Journal of Cancer, 80 (8), 1252-1258. doi: 10.1038/sj.bjc.6690493 |
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1999 Journal Article The possible origin of free radicals from amyloid peptides in Alzheimer's diseaseBush, A. I., Huang, X. and Fairlie, D. (1999). The possible origin of free radicals from amyloid peptides in Alzheimer's disease. Neurobiology of Aging, 20 (3), 335-337. doi: 10.1016/S0197-4580(99)00058-5 |
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1999 Journal Article Con formational homogeneity in molecular recognition by proteolytic enzymesTyndall, J. and Fairlie, D. (1999). Con formational homogeneity in molecular recognition by proteolytic enzymes. Journal of Molecular Recognition, 12 (6), 363-370. doi: 10.1002/(SICI)1099-1352(199911/12)12:63.3.CO;2-D |
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1999 Journal Article Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5aFinch, A., Wong, A. K., Paczkowski, N. J., Wadi, S. K., Craik, D. J., Fairlie, D. and Taylor, S. M. (1999). Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a. Journal of Medicinal Chemistry, 42 (6), 1965-1974. doi: 10.1021/jm9806594 |
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1999 Journal Article Cu (II ) Potentiation of Alzheimer Ab NeurotoxicityHuang, X., Cuajungco, M. P., Atwood, C. S., Hartshorn, M. A., Tyndall, J. D., Hanson, G. R., Stokes, K. C., Leopold, M., Multhaup, G., Goldstein, L. E., Scarpa, R. C., Saunders, A. J., Lim, J., Moir, R. D., Glabe, C., Bowden, E. F., Masters, C. L., Fairlie, D., Tanzi, R. E. and Bush, A. I. (1999). Cu (II ) Potentiation of Alzheimer Ab Neurotoxicity. Jornal of Biological Chemistry, 274 (52), 37111-37116. |
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1999 Journal Article X-ray absorption spectroscopy of cadmium phytochelatin and model systemsPickering, I. J., Prince, R. C., George, G. N., Rauser, W. E., Wickramasinghe, W. A., Watson, A. A., Dameron, C., Dance, I. G., Fairlie, D. and Salt, D. E. (1999). X-ray absorption spectroscopy of cadmium phytochelatin and model systems. Biochimica Et Biophysica Acta, 1429 (2), 351-364. doi: 10.1016/S0167-4838(98)00242-8 |
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1999 Journal Article Development of C5a receptor antagonistsWong, A., Taylor, S. M. and Fairlie, D. (1999). Development of C5a receptor antagonists. Investigational Drugs, 2 (7), 686-693. |
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1999 Journal Article Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 proteaseMartin, J. L., Begun, J., Schindeler, A., Wickramasinghe, W. A., Alewood, D., Alewood, P. F., Bergman, D. A., Brinkworth, R. I., Abbenante, G., March, D. R., Reid, R. C., Fairlie, D. P. and Armstrong, Richard A. (1999). Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38 (25), 7978-7988. doi: 10.1021/bi990174x |
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1999 Journal Article Aqueous Dissolution of Alzheimer's Disease Ab Amyloid Deposits by Biometal DepletionCherny, R. A., Legg, J. T., McLean, C. A., Fairlie, D., Huang, X., Atwood, C.S., Beyreuther, K., Tanzi, R. E., Masters, C. L. and Bush, A. (1999). Aqueous Dissolution of Alzheimer's Disease Ab Amyloid Deposits by Biometal Depletion. Journal of Biological Chemistry, 274 (33), 23223-23228. doi: 10.1074/jbc.274.33.23223 |
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1999 Journal Article Interaction of zinc(II) with the cyclic octapeptides, cyclo[Ile(Oxn)-D-Val(Thz)](2) and ascidiacyclamide, a cyclic peptide from Lissoclinum patellaGrondahl, L., Sokolenko, N., Abbenante, G., Fairlie, D. P., Hanson, G. R. and Gahan, L. R. (1999). Interaction of zinc(II) with the cyclic octapeptides, cyclo[Ile(Oxn)-D-Val(Thz)](2) and ascidiacyclamide, a cyclic peptide from Lissoclinum patella. Journal of The Chemical Society-dalton Transactions (8), 1227-1234. doi: 10.1039/a808836e |
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1999 Journal Article Facile and steroselective condensation of acetone with ammonia ligands on cobalt ( III):structure of a N-bonded cyanate complex containing the 2-methyl-2-amino-4-imino-pentane ligandFairlie, D., Turner, M., Byriel, K., McKeon, J. A. and Jackson, G. W. (1999). Facile and steroselective condensation of acetone with ammonia ligands on cobalt ( III):structure of a N-bonded cyanate complex containing the 2-methyl-2-amino-4-imino-pentane ligand. Inorganica Chimica Acta, 290 (2), 133-138. doi: 10.1016/S0020-1693(99)00110-3 |
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1999 Journal Article Cyclooligomerization of Thiazole-Containing Tetrapeptides. Symmetrical Macrocycles with up to 76 Amino AcidsSokolenko, N., Abbenante, G., Scanlon, M. J., Jones, A., Gahan, L. R., Hanson, G. R. and Fairlie, D. P. (1999). Cyclooligomerization of Thiazole-Containing Tetrapeptides. Symmetrical Macrocycles with up to 76 Amino Acids. Journal of the American Chemical Society, 121 (11), 2603-2604. doi: 10.1021/ja983354n |
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1998 Journal Article Template assembled synthetic proteins (TASPS). Are template size, shape, and directionality important in formation of four-helix bundles?Wong A.K., Jacobsen M.P., Winzor D.J. and Fairlie D.P. (1998). Template assembled synthetic proteins (TASPS). Are template size, shape, and directionality important in formation of four-helix bundles?. Journal of the American Chemical Society, 120 (16), 3836-3841. doi: 10.1021/ja971951o |
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1998 Journal Article Small molecular probes for G-protein-coupled C5a receptors: Conformationally constrained antagonists derived from the C terminus of the human plasma protein C5aWong, AK, Finch, AM, Pierens, GK, Craik, DJ, Taylor, SM and Fairlie, DP (1998). Small molecular probes for G-protein-coupled C5a receptors: Conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a. Journal of Medicinal Chemistry, 41 (18), 3417-3425. doi: 10.1021/jm9800651 |
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1998 Journal Article Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?Coles, M, Bicknell, W, Watson, AA, Fairlie, DP and Craik, DJ (1998). Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?. Biochemistry, 37 (31), 11064-11077. doi: 10.1021/bi972979f |
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1998 Journal Article Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching?Watson, AA, Fairlie, DP and Craik, DJ (1998). Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching?. Biochemistry, 37 (37), 12700-12706. doi: 10.1021/bi9810757 |
