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1998 Journal Article Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?Coles, M, Bicknell, W, Watson, AA, Fairlie, DP and Craik, DJ (1998). Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?. Biochemistry, 37 (31), 11064-11077. doi: 10.1021/bi972979f |
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1998 Journal Article Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching?Watson, AA, Fairlie, DP and Craik, DJ (1998). Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching?. Biochemistry, 37 (37), 12700-12706. doi: 10.1021/bi9810757 |
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1997 Journal Article Simple cis-epoxide-based inhibitors of HIV-1 proteaseAbell A.D., Hoult D.A., Bergman D.A. and Fairlie D.P. (1997). Simple cis-epoxide-based inhibitors of HIV-1 protease. Bioorganic & Medicinal Chemistry Letters, 7 (22), 2853-2856. doi: 10.1016/S0960-894X(97)10106-8 |
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1997 Journal Article Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cellsParsons, P. G., Hansen, C., Fairlie, D. P., West, M. L., Danoy, P. A. C., Sturm, R. A., Dunn, I. S., Pedley, J. and Ablett, E. M. (1997). Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cells. Biochemical Pharmacology, 53 (11), 1719-1724. doi: 10.1016/S0006-2952(97)00016-6 |
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1997 Journal Article Activation of thiourea bound through sulfur to pentaammineruthenium(III): Structure and reactivityFairlie, DP, Wickramasinghe, WA, Byriel, KA and Taube, H (1997). Activation of thiourea bound through sulfur to pentaammineruthenium(III): Structure and reactivity. Inorganic Chemistry, 36 (11), 2242-2243. doi: 10.1021/ic9611397 |
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1997 Journal Article Models for arginine-metal binding. Synthesis of guanidine and urea ligands through amination and hydration of a cyanamide ligand bound to platinum(II), osmium(III), and cobalt(III)Fairlie, David P., Jackson, W. Gregory, Skelton, Brian W., Wen, Huo, White, Allan H., Wickramasinghe, Wasantha A., Woon, Tai Chin and Taube, Henry (1997). Models for arginine-metal binding. Synthesis of guanidine and urea ligands through amination and hydration of a cyanamide ligand bound to platinum(II), osmium(III), and cobalt(III). Inorganic Chemistry, 36 (6), 1020-1028. doi: 10.1021/ic961138e |
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1997 Journal Article Oxygen versus nitrogen bonding of carboxamides to pentaammineruthenium(II/III)Fairlie, David P., Ilan, Yigal and Taube, Henry (1997). Oxygen versus nitrogen bonding of carboxamides to pentaammineruthenium(II/III). Inorganic Chemistry, 36 (6), 1029-1037. doi: 10.1021/ic9611406 |
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1997 Journal Article Biphasic response of the metallothionein promoter to ultraviolet radiation in human melanoma cellsHansen, C., Ablett, E., Green, A., Sturm, R. A., Dunn, I. S., Fairlie, D. P., West, M. L. and Parsons, P. G. (1997). Biphasic response of the metallothionein promoter to ultraviolet radiation in human melanoma cells. Photochemistry and Photobiology, 65 (3), 550-555. doi: 10.1111/j.1751-1097.1997.tb08603.x |
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1997 Journal Article Organization of amino acids using a metallotriazacyclononane templateWatson, AA, Willis, AC and Fairlie, DP (1997). Organization of amino acids using a metallotriazacyclononane template. Inorganic Chemistry, 36 (5), 752-&. doi: 10.1021/ic960867r |
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1997 Journal Article A novel strategy for the design of potent peptidomimetic inhibitors of proteolytic enzymes: Application to HIV-1 protease.Reid, R. C., Abbenante, G., March, D. R., Scanlon, M. and Fairlie, D. P. (1997). A novel strategy for the design of potent peptidomimetic inhibitors of proteolytic enzymes: Application to HIV-1 protease.. Abstracts of Papers of The American Chemical Society, 214, 177-MEDI. |
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1997 Journal Article Conformationally constrained cyclic mimetics of protein and peptide surfaces.Wong, A. K., Reid, R. C., Abbenante, J. and Fairlie, D. P. (1997). Conformationally constrained cyclic mimetics of protein and peptide surfaces.. Abstracts of Papers of The American Chemical Society, 214 (1), 388-ORGN. |
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1997 Journal Article Conformationally constrained small molecule antagonists of C5a.Wong, AK, Finch, AM, Pierens, GK, Taylor, SM and Fairlie, DP (1997). Conformationally constrained small molecule antagonists of C5a.. Abstracts of Papers of The American Chemical Society, 214, 9-MEDI. |
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1997 Journal Article The role of oxazoline and thiazole ring constraints in cyclic peptides of marine origin.Abbenante, G., Sokolenko, N. and Fairlie, D. P. (1997). The role of oxazoline and thiazole ring constraints in cyclic peptides of marine origin.. Abstracts of Papers of The American Chemical Society, 214, 389-ORGN. |
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1996 Journal Article Structure-activity relationships for macrocyclic peptidomimetic inhibitors of HIV-1 protease.Abbenante, G., Bergman, D. A., Brinkworth, R. I., March, D. R., Reid, R. C., Hunt, P. A., James, I. W., Dancer, R. J., Garnham, B., Stoermer, M. L. and Fairlie, D. P. (1996). Structure-activity relationships for macrocyclic peptidomimetic inhibitors of HIV-1 protease.. Bioorganic & Medicinal Chemistry Letters, 6 (21), 2531-2536. doi: 10.1016/0960-894X(96)00468-4 |
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1996 Journal Article Conformational control by thiazole and oxazoline rings in cyclic octapeptides of marine origin. Novel macrocyclic chair and boat conformationsAbbenante, G., Fairlie, D. P., Gahan, L. R., Hanson, G. R., Pierens, G. K. and van den Brenk, A. L. (1996). Conformational control by thiazole and oxazoline rings in cyclic octapeptides of marine origin. Novel macrocyclic chair and boat conformations. Journal of the American Chemical Society, 118 (43), 10384-10388. doi: 10.1021/ja962260f |
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1996 Journal Article A novel bicyclic enzyme inhibitor as a consensus peptidomimetic for the receptor-bound conformations of 12 peptidic inhibitors of HIV-1 proteaseReid, Robert C., March, Darren R., Dooley, Michael J., Bergman, Doug A., Abbenante, Giovanni and Fairlie, David P. (1996). A novel bicyclic enzyme inhibitor as a consensus peptidomimetic for the receptor-bound conformations of 12 peptidic inhibitors of HIV-1 protease. Journal of The American Chemical Society, 118 (36), 8511-8517. doi: 10.1021/ja960433v |
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1996 Journal Article Structure of a novel protonated oxadiazine: an unusual heterocycle from the cycloaddition of a ketone with nitrilesKennard, Colin H.L., Byriel, Karl A., Woon, Tai Chin and Fairlie, David P. (1996). Structure of a novel protonated oxadiazine: an unusual heterocycle from the cycloaddition of a ketone with nitriles. Chemical Communications (15), 1731-1732. doi: 10.1039/cc9960001731 |
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1996 Journal Article Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding modeMarch, D. R., Abbenante, G., Bergman, D. A., Brinkworth, R. I., Wickramasinghe, W., Begun, J., Martin, J. L. and Fairlie, D. P. (1996). Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode. Journal of The American Chemical Society, 118 (14), 3375-3379. doi: 10.1021/ja953790z |
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1996 Journal Article A novel potassium-binding hydrolysis product of ascidiacyclamide, a cyclic peptide isolated from the ascidian lissoclinum patellavan den Brenk, Anna L., Fairlie, David P., Gahan, Lawrence R., Hanson, Graeme R. and Hambley, Trevor W. (1996). A novel potassium-binding hydrolysis product of ascidiacyclamide, a cyclic peptide isolated from the ascidian lissoclinum patella. Inorganic Chemistry, 35 (5), 1095-1100. doi: 10.1021/ic9504755 |
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1996 Journal Article Non-peptide inhibitors of HIV-1 protease. Synthesis and structural evaluation of symmetric and non-symmetric naphthalenesulfonic acid analoguesWong M.F., Huang P.P., Brinkworth R.I., Yashiro M., Mohan P., Fairlie D.P., Baba M. and Verma S. (1996). Non-peptide inhibitors of HIV-1 protease. Synthesis and structural evaluation of symmetric and non-symmetric naphthalenesulfonic acid analogues. European Journal of Medicinal Chemistry, 31 (3), 249-255. doi: 10.1016/0223-5234(96)89141-0 |
