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2002 Journal Article Cleavage of hemoglobin by hookworm cathespin D aspartic proteases and its potential contribution to host specificityWilliamson, Angela L., Brindley, Paul J., Abbenante, Giovanni, Prociv, Paul, Berry, Colin, Girdwood, Karen, Pritchard, David I., Fairlie, David P., Hotez, Peter J., Dalton, John P. and Loukas, Alex C. (2002). Cleavage of hemoglobin by hookworm cathespin D aspartic proteases and its potential contribution to host specificity. The FASEB Journal, 16 (10), 1458-1460. doi: 10.1096/fj.02-0181fje |
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2002 Journal Article Protective effect of a new C5a receptor antagonist against Ischemia-reperfusion injury in the rat small intestineArumugam, Thiruma V., Shiels, Ian A., Woodruff, Trent M., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002). Protective effect of a new C5a receptor antagonist against Ischemia-reperfusion injury in the rat small intestine. Journal of Surgical Research, 103 (2), 260-267. doi: 10.1006/jsre.2002.6369 |
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2002 Journal Article Synthesis and structural properties of patellamide a derivatives and their copper(II) compoundsBernhardt, P. V., Comba, P., Fairlie, D. P., Gahan, L. R., Hanson, G. R. and Lotzbeyer, L. (2002). Synthesis and structural properties of patellamide a derivatives and their copper(II) compounds. Chemistry-a European Journal, 8 (7), 1527-1536. doi: 10.1002/1521-3765(20020402)8:73.3.CO;2-6 |
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2002 Journal Article Mimetics of the Peptide beta-StrandGlenn, Matthew P. and Fairlie, David P. (2002). Mimetics of the Peptide beta-Strand. Mini-Reviews in Medicinal Chemistry, 2 (5), 433-445. doi: 10.2174/1389557023405747 |
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2002 Journal Article Cyclic octapeptides containing thiazole. Effect of stereochemistry and degree of flexibility on calcium binding propertiesCusack, R. M., Grondahl, L., Fairlie, D. P., Gahan, L. R. and Hanson, G. R. (2002). Cyclic octapeptides containing thiazole. Effect of stereochemistry and degree of flexibility on calcium binding properties. Journal of The Chemical Society-perkin Transactions 2 (3), 556-563. doi: 10.1039/b109168a |
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2002 Journal Article Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solventsReid, RC, Kelso, MJ, Scanlon, MJ and Fairlie, DP (2002). Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents. Journal of The American Chemical Society, 124 (20), 5673-5683. doi: 10.1021/ja0256461 |
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2002 Journal Article Catalytically active Dengue virus NS3 protease forms aggregates that are separable by size exclusion chromatographyArakaki, T. L., Fang, N. X., Fairlie, D. P., Young, P. R. and Martin, J. L. (2002). Catalytically active Dengue virus NS3 protease forms aggregates that are separable by size exclusion chromatography. Protein Expression And Purification, 25 (2), 241-247. doi: 10.1016/S1046-5928(02)00005-0 |
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2002 Journal Article Deactivation of the chlorosulfonate ion coordinated to pentaamminecobalt(III)Fairlie, DP, Dutton, BH, Mckeon, JA and Jackson, WG (2002). Deactivation of the chlorosulfonate ion coordinated to pentaamminecobalt(III). Inorganic Reaction Mechanisms, 4 (3-4), 197-208. doi: 10.1080/1028662021000062626 |
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2002 Journal Article Mimetics of the peptide b-strandGlenn, M. P. and Fairlie, D. P. (2002). Mimetics of the peptide b-strand. Mini reviews in Medicinal Chemistry, 2, 433-445. |
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2002 Journal Article Mimetics of the peptide beta-strand.Glenn M.P. and Fairlie D.P. (2002). Mimetics of the peptide beta-strand.. Mini reviews in medicinal chemistry, 2 (5), 433-445. |
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2002 Journal Article Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazolesSingh, Y, Stoermer, MJ, Lucke, AJ, Glenn, MP and Fairlie, DP (2002). Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles. Organic Letters, 4 (20), 3367-3370. doi: 10.1021/ol026463m |
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2002 Journal Article Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist (vol 134, pg 1778, 2001)Strachan, Anna J., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002). Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist (vol 134, pg 1778, 2001). British Journal of Pharmacology, 135 (2), 579-580. doi: 10.1038/sj.bjp.0704531 |
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2002 Journal Article beta-strand mimicking macrocyclic amino acids: Templates for protease inhibitors with antiviral activityGlenn, MP, Pattenden, LK, Reid, RC, Tyssen, DP, Tyndall, JDA, Birch, CJ and Fairlie, DP (2002). beta-strand mimicking macrocyclic amino acids: Templates for protease inhibitors with antiviral activity. Journal of Medicinal Chemistry, 45 (2), 371-381. doi: 10.1021/jm010414i |
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2001 Journal Article Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitorsLeung, D., Schroder, K., White, H., Fang, N. X., Stoermer, M. J., Abbenante, G., Martin, J. L., Young, P. R. and Fairlie, D. P. (2001). Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors. Journal of Biological Chemistry, 276 (49), 45762-45771. doi: 10.1074/jbc.M107360200 |
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2001 Journal Article Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonistStrachan, Anna J., Shiels, Ian A., Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and R. A. North (2001). Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist. British Journal of Pharmacology, 134 (12), 1778-1786. doi: 10.1038/sj.bjp.0704417 |
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2001 Journal Article Protease inhibitorsFairlie, DP (2001). Protease inhibitors. Current Medicinal Chemistry, 8 (8), U2-U2. |
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2001 Journal Article Species dependence for binding of small molecule agonist and antagonists to the C5a receptor on polymorphonuclear leukocytesWoodruff, Trent M., Strachan, Anna J., Sanderson, Sam D., Monk, Peter N., Wong, Allan K., Fairlie, David P. and Taylor, Stephen M. (2001). Species dependence for binding of small molecule agonist and antagonists to the C5a receptor on polymorphonuclear leukocytes. Inflammation, 25 (3), 171-177. doi: 10.1023/A:1011036414353 |
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2001 Journal Article Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptorCain, S. A., Woodruff, T. M., Taylor, S. M., Fairlie, D. P., Sanderson, S. D. and Monk, P. N. (2001). Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor. Biochemical Pharmacology, 61 (12), 1571-1579. doi: 10.1016/S0006-2952(01)00608-6 |
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2001 Journal Article Macrocycles mimic the extended peptide conformation recognized by aspartic, serine, cysteine and metallo proteasesTyndall, JDA and Fairlie, DP (2001). Macrocycles mimic the extended peptide conformation recognized by aspartic, serine, cysteine and metallo proteases. Current Medicinal Chemistry, 8 (8), 893-907. doi: 10.2174/0929867013372715 |
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2001 Journal Article Novel Cylindrical, Conical, and Macrocyclic Peptides from the Cyclooligomerization of Functionalized Thiazole Amino AcidsSingh, Y., Sokolenko, N., Kelso, M. J., Gahan, L. R., Abbenante, G. and Fairlie, D. P. (2001). Novel Cylindrical, Conical, and Macrocyclic Peptides from the Cyclooligomerization of Functionalized Thiazole Amino Acids. Journal of the American Chemical Society, 123 (2), 333-334. doi: 10.1021/ja002666z |
