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2021 Journal Article Rapid initiation of cell cycle reentry processes protects neurons from amyloid-β toxicityIppati, Stefania, Deng, Yuanyuan, van der Hoven, Julia, Heu, Celine, van Hummel, Annika, Chua, Sook Wern, Paric, Esmeralda, Chan, Gabriella, Feiten, Astrid, Fath, Thomas, Ke, Yazi D., Haass, Nikolas K. and Ittner, Lars M. (2021). Rapid initiation of cell cycle reentry processes protects neurons from amyloid-β toxicity. Proceedings of the National Academy of Sciences, 118 (12) e2011876118, e2011876118. doi: 10.1073/pnas.2011876118 |
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2021 Journal Article Mathematical model of tumour spheroid experiments with real-time cell cycle imagingJin, Wang, Spoerri, Loredana, Haass, Nikolas K. and Simpson, Matthew J. (2021). Mathematical model of tumour spheroid experiments with real-time cell cycle imaging. Bulletin of Mathematical Biology, 83 (5) 44, 1-23. doi: 10.1007/s11538-021-00878-4 |
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2021 Journal Article A novel mathematical model of heterogeneous cell proliferationVittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2021). A novel mathematical model of heterogeneous cell proliferation. Journal of Mathematical Biology, 82 (5) 34, 34. doi: 10.1007/s00285-021-01580-8 |
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2020 Journal Article Editorial: recent developments in therapies and diagnostic tools for melanoma and non-melanoma skin cancerFujimura, Taku, Fujisawa, Yasuhiro, Otsuka, Atsushi and Haass, Nikolas K. (2020). Editorial: recent developments in therapies and diagnostic tools for melanoma and non-melanoma skin cancer. Frontiers in Medicine, 7 613152, 613152. doi: 10.3389/fmed.2020.613152 |
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2020 Journal Article Abrogation of RAB27A expression transiently affects melanoma cell proliferationGuo, Dajiang, Beaumont, Kimberley A., Sharp, Danae M., Lui, Goldie Y. L., Weninger, Wolfgang, Haass, Nikolas K. and Tikoo, Shweta (2020). Abrogation of RAB27A expression transiently affects melanoma cell proliferation. Pigment Cell and Melanoma Research, 33 (6), 889-894. doi: 10.1111/pcmr.12903 |
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2020 Journal Article Examining go-or-grow using fluorescent cell-cycle indicators and cell-cycle-inhibiting drugsVittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2020). Examining go-or-grow using fluorescent cell-cycle indicators and cell-cycle-inhibiting drugs. Biophysical journal, 118 (6), 1243-1247. doi: 10.1016/j.bpj.2020.01.036 |
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2019 Journal Article Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferationVittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2019). Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferation. Journal of The Royal Society Interface, 16 (157) 20190382, 20190382. doi: 10.1098/rsif.2019.0382 |
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2019 Journal Article Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabineOo, Zay Yar, Proctor, Martina, Stevenson, Alexander J., Nazareth, Deborah, Fernando, Madushan, Daignault, Sheena M., Lanagan, Catherine, Walpole, Sebastian, Bonazzi, Vanessa, Škalamera, Dubravka, Snell, Cameron, Haass, Nikolas K., Larsen, Jill E. and Gabrielli, Brian (2019). Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine. Molecular Oncology, 13 (7) 1878-0261.12497, 1503-1518. doi: 10.1002/1878-0261.12497 |
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2019 Journal Article RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomesGuo, Dajiang, Lui, Goldie Y. L., Lai, Siew Li, Wilmott, James S., Tikoo, Shweta, Jackett, Louise A., Quek, Camelia, Brown, Darren L., Sharp, Danae M., Kwan, Rain Y. Q., Chacon, Diego, Wong, Jason H., Beck, Dominik, van Geldermalsen, Michelle, Holst, Jeff, Thompson, John F., Mann, Graham J., Scolyer, Richard A., Stow, Jennifer L., Weninger, Wolfgang, Haass, Nikolas K. and Beaumont, Kimberley A. (2019). RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. International Journal of Cancer, 144 (12), 3070-3085. doi: 10.1002/ijc.32064 |
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2019 Journal Article RAB27A-mediated melanoma exosomes: promoters of invasion and metastasisGuo, Dajiang, Tikoo, Shweta and Haass, Nikolas K. (2019). RAB27A-mediated melanoma exosomes: promoters of invasion and metastasis. Translational Cancer Research, 8 (3), 732-735. doi: 10.21037/tcr.2019.04.25 |
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2019 Journal Article BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survivalLee, Erinna F., Harris, Tiffany J., Tran, Sharon, Evangelista, Marco, Arulananda, Surein, John, Thomas, Ramnac, Celeste, Hobbs, Chloe, Zhu, Haoran, Gunasingh, Gency, Segal, David, Behren, Andreas, Cebon, Jonathan, Dobrovic, Alexander, Mariadason, John M., Strasser, Andreas, Rohrbeck, Leona, Haass, Nikolas K., Herold, Marco J. and Fairlie, W. Douglas (2019). BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival. Cell Death & Disease, 10 (5) 342, 342. doi: 10.1038/s41419-019-1568-3 |
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2019 Journal Article Cover imageEmran, Abdullah Al, Chinna Chowdary, Brinda Reddy, Ahmed, Farzana, Hammerlindl, Heinz, Huefner, Antje, Haass, Nikolas K., Schuehly, Wolfgang and Schaider, Helmut (2019). Cover image. Cancer Medicine, 8 (3), i-i. doi: 10.1002/cam4.2129 |
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2019 Journal Article Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanomaEmran, Abdullah Al, Chinna Chowdary, Brinda Reddy, Ahmed, Farzana, Hammerlindl, Heinz, Huefner, Antje, Haass, Nikolas K., Schuehly, Wolfgang and Schaider, Helmut (2019). Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma. Cancer Medicine, 8 (3), 1186-1196. doi: 10.1002/cam4.1978 |
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2018 Journal Article Stochastic models of cell invasion with fluorescent cell cycle indicatorsSimpson, Matthew J., Jin, Wang, Vittadello, Sean T., Tambyah, Tamara A., Ryan, Jacob M., Gunasingh, Gency, Haass, Nikolas K. and McCue, Scott W. (2018). Stochastic models of cell invasion with fluorescent cell cycle indicators. Physica A: Statistical Mechanics and its Applications, 510, 375-386. doi: 10.1016/j.physa.2018.06.128 |
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2018 Journal Article The role of melanoma cell-stroma interaction in cell motility, invasion, and metastasisJu, Robert J., Stehbens, Samantha J. and Haass, Nikolas K. (2018). The role of melanoma cell-stroma interaction in cell motility, invasion, and metastasis. Frontiers in Medicine, 5 (NOV) 307, 1-9. doi: 10.3389/fmed.2018.00307 |
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2018 Journal Article FGFR2b activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancerStehbens, Samantha J., Ju, Robert J., Adams, Mark N., Perry, Samuel, Haass, Nikolas K., Bryant, David M. and Pollock, Pamela M. (2018). FGFR2b activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer. Journal of Cell Science, 131 (15) jcs.213678, 1-16. doi: 10.1242/jcs.213678 |
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2018 Journal Article Endogenous replication stress marks melanomas sensitive to CHEK1 inhibitors in vivoOo, Zay Yar, Stevenson, Alexander J., Proctor, Martina A., Daignault, Sheena M., Walpole, Sebastian, Lanagan, Catherine, Chen, James, Skalamera, Dubravka, Spoerri, Loredana, Ainger, Stephen, Sturm, Richard A, Haass, Nikolas K and Gabrielli, Brian (2018). Endogenous replication stress marks melanomas sensitive to CHEK1 inhibitors in vivo. Clinical Cancer Research, 24 (12), 2901-2912. doi: 10.1158/1078-0432.CCR-17-2701 |
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2018 Journal Article Microenvironment-driven dynamic heterogeneity and phenotypic plasticity as a mechanism of melanoma therapy resistanceAhmed, Farzana and Haass, Nikolas K. (2018). Microenvironment-driven dynamic heterogeneity and phenotypic plasticity as a mechanism of melanoma therapy resistance. Frontiers in Oncology, 8 (May) 173, 1-7. doi: 10.3389/fonc.2018.00173 |
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2018 Journal Article HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanomaGallagher, Stuart J., Gunatilake, Dilini, Beaumont, Kimberley A., Sharp, Danae M., Tiffen, Jessamy C., Heinemann, Anja, Weninger, Wolfgang, Haass, Nikolas K., Wilmott, James S., Madore, Jason, Ferguson, Peter M., Rizos, Helen and Hersey, Peter (2018). HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. International Journal of Cancer, 142 (9), 1926-1937. doi: 10.1002/ijc.31199 |
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2018 Journal Article Mathematical models for cell migration with real-time cell cycle dynamicsVittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K and Simpson, Matthew J (2018). Mathematical models for cell migration with real-time cell cycle dynamics. Biophysical Journal, 114 (5), 1241-1253. doi: 10.1016/j.bpj.2017.12.041 |
