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2018

Journal Article

Acetylsalicylic acid governs the effect of sorafenib in RAS- mutant cancers

Hammerlindl, Heinz, Ravindran Menon, Dinoop, Hammerlindl, Sabrina, Emran, Abdullah Al, Torrano, Joachim, Sproesser, Katrin, Thakkar, Divya, Xiao, Min, Atkinson, Victoria G., Gabrielli, Brian, Haass, Nikolas K., Herlyn, Meenhard, Krepler, Clemens and Schaider, Helmut (2018). Acetylsalicylic acid governs the effect of sorafenib in RAS- mutant cancers. Clinical Cancer Research, 24 (5), 1090-1102. doi: 10.1158/1078-0432.CCR-16-2118

Acetylsalicylic acid governs the effect of sorafenib in RAS- mutant cancers

2017

Journal Article

Dendritic mesoporous silica nanoparticles for pH-stimuli-responsive drug delivery of TNF-alpha

Kienzle, Arne, Kurch, Sven, Schloder, Janine, Berges, Carsten, Ose, Robert, Schupp, Jonathan, Tuettenberg, Andrea, Weiss, Henning, Schultze, Jennifer, Winzen, Svenja, Schinnerer, Meike, Koynov, Kaloian, Mezger, Markus, Haass, Nikolas K., Tremel, Wolfgang and Jonuleit, Helmut (2017). Dendritic mesoporous silica nanoparticles for pH-stimuli-responsive drug delivery of TNF-alpha. Advanced Healthcare Materials, 6 (13) 1700012, 1700012+. doi: 10.1002/adhm.201700012

Dendritic mesoporous silica nanoparticles for pH-stimuli-responsive drug delivery of TNF-alpha

2017

Journal Article

Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure

Smith, Michael P., Rowling, Emily J., Miskolczi, Zsofia, Ferguson, Jennifer, Spoerri, Loredana, Haass, Nikolas K., Sloss, Olivia, Mcentegart, Sophie, Arozarena, Imanol, von Kriegsheim, Alex, Rodriguez, Javier, Brunton, Holly, Kmarashev, Jivko, Levesque, Mitchell P., Dummer, Reinhard, Frederick, Dennie T., Andrews, Miles C., Cooper, Zachary A., Flaherty, Keith T., Wargo, Jennifer A. and Wellbrock, Claudia (2017). Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure. EMBO Molecular Medicine, 9 (8), 1011-1029. doi: 10.15252/emmm.201607156

Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure

2017

Journal Article

Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunities

Haass, Nikolas K. and Gabrielli, Brian (2017). Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunities. Experimental Dermatology, 26 (7), 649-655. doi: 10.1111/exd.13303

Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunities

2017

Journal Article

NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF

Fane, Mitchell E., Chhabra, Yash, Hollingsworth, David E. J., Simmons, Jacinta L., Spoerri, Loredana, Oh, Tae Gyu, Chauhan, Jagat, Chin, Toby, Harris, Lachlan, Harvey, Tracey J., Muscat, George E. O., Goding, Colin R., Sturm, Richard A., Haass, Nikolas K., Boyle, Glen M., Piper, Michael and Smith, Aaron G. (2017). NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF. EBioMedicine, 16, 63-75. doi: 10.1016/j.ebiom.2017.01.013

NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF

2016

Journal Article

JNK-ERK signalling in melanoma: rewired or entangled?

Haass, N. K. (2016). JNK-ERK signalling in melanoma: rewired or entangled?. British Journal of Dermatology, 175 (6), 1139-1140. doi: 10.1111/bjd.14903

JNK-ERK signalling in melanoma: rewired or entangled?

2016

Journal Article

Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer

Maadi, Hamid, Moshtaghian, Abdolvahab, Taha, Masoumeh Fakhr, Mowla, Seyed Javad, Kazeroonian, Asiye, Haass, Nikolas K. and Javeri, Arash (2016). Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer. International Journal of Biochemistry and Cell Biology, 81 (A), 121-132. doi: 10.1016/j.biocel.2016.11.004

Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer

2016

Journal Article

Zielgerichtete Melanomtherapie – Die Rolle der dynamischen Tumorheterogenität

Haass, Nikolas K. (2016). Zielgerichtete Melanomtherapie – Die Rolle der dynamischen Tumorheterogenität. Spectrum Dermatologie, 2016 (3), 14-17.

Zielgerichtete Melanomtherapie – Die Rolle der dynamischen Tumorheterogenität

2016

Journal Article

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

Skalamera, Dubravka, Dahmer-Heath, Mareike, Stevenson, Alexander J., Pinto, Cletus, Shah, Esha T., Daignault, Sheena M., Said, Nur Akmarina B. M., Davis, Melissa, Haass, Nikolas K., Williams, Elizabeth D., Hollier, Brett G., Thompson, Erik W., Gabrielli, Brian and Gonda, Thomas J. (2016). Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer. Oncotarget, 7 (38), 61000-61020. doi: 10.18632/oncotarget.11314

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

2016

Journal Article

Cell cycle phase-specific drug resistance as an escape mechanism of melanoma cells

Beaumont, Kimberley A., Hill, David S., Daignault, Sheena M., Lui, Goldie Y. L., Sharp, Danae M., Gabrielli, Brian, Weninger, Wolfgang and Haass, Nikolas K. (2016). Cell cycle phase-specific drug resistance as an escape mechanism of melanoma cells. Journal of Investigative Dermatology, 136 (7), 1479-1489. doi: 10.1016/j.jid.2016.02.805

Cell cycle phase-specific drug resistance as an escape mechanism of melanoma cells

2016

Journal Article

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB

Giles, Keith M., Brown, Rikki A. M., Ganda, Clarissa, Podgorny, Melissa J., Candy, Patrick A., Wintle, Larissa C., Richardson, Kirsty L., Kalinowski, Felicity C., Stuart, Lisa M., Epis, Michael R., Haass, Nikolas K., Herlyn, Meenhard and Leedman, Peter J. (2016). microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB. Oncotarget, 7 (22), 31663-31680. doi: 10.18632/oncotarget.9421

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB

2016

Journal Article

In vivo overexpression of Emi1 promotes chromosome instability and tumorigenesis

Vaidyanathan, Srividya, Cato, Kathleen, Tang, Lu, Pavey, Sandra, Haass, Nikolas K., Gabrielli, Brian G. and Duijf, Pascal H. G. (2016). In vivo overexpression of Emi1 promotes chromosome instability and tumorigenesis. Oncogene, 35 (41), 5446-5455. doi: 10.1038/onc.2016.94

In vivo overexpression of Emi1 promotes chromosome instability and tumorigenesis

2015

Journal Article

Imaging- and flow cytometry-based analysis of cell position and the cell cycle in 3d melanoma spheroids

Beaumont, Kimberley A., Anfosso, Andrea, Ahmed, Farzana, Weninger, Wolfgang and Haass, Nikolas K. (2015). Imaging- and flow cytometry-based analysis of cell position and the cell cycle in 3d melanoma spheroids. Journal of Visualized Experiments, 106 (e53486) e53486, e53486. doi: 10.3791/53486

Imaging- and flow cytometry-based analysis of cell position and the cell cycle in 3d melanoma spheroids

2015

Journal Article

Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS

Ke, Yazi D., van Hummel, Annika, Stevens, Claire H., Gladbach, Amadeus, Ippati, Stefania, Bi, Mian, Lee, Wei S., Kruger, Sarah, van der Hoven, Julia, Volkerling, Alexander, Bongers, Andre, Halliday, Glenda, Haass, Nikolas K., Kiernan, Matthew, Delerue, Fabien and Ittner, Lars M. (2015). Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS. Acta Neuropathologica, 130 (5), 661-678. doi: 10.1007/s00401-015-1486-0

Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS

2015

Journal Article

A stress-induced early innate response causes multidrug tolerance in melanoma

Ravindran Menon, D., Das, S., Krepler, C., Vultur, A., Rinner, B., Schauer, S., Kashofer, K., Wagner, K., Zhang, G., Bonyadi Rad, E., Haass, N. K., Soyer, H. P., Gabrielli, B., Somasundaram, R., Hoefler, G., Herlyn, M. and Schaider, H. (2015). A stress-induced early innate response causes multidrug tolerance in melanoma. Oncogene, 34 (34), 4448-4459. doi: 10.1038/onc.2014.372

A stress-induced early innate response causes multidrug tolerance in melanoma

2015

Journal Article

Corrigendum: a stress-induced early innate response causes multidrug tolerance in melanoma (vol 34, pg 4448, 2015)

Menon, D. Ravindran, Das, S., Krepler, C., Vultur, A., Rinner, B., Schauer, S., Kashofer, K., Wagner, K., Zhang, G., Rad, E. Bonyadi, Haass, N. K., Soyer, H. P., Gabrielli, B., Somasundaram, R., Hoefler, G., Herlyn, M. and Schaider, H. (2015). Corrigendum: a stress-induced early innate response causes multidrug tolerance in melanoma (vol 34, pg 4448, 2015). Oncogene, 34 (34), 4545-4545. doi: 10.1038/onc.2014.432

Corrigendum: a stress-induced early innate response causes multidrug tolerance in melanoma (vol 34, pg 4448, 2015)

2015

Journal Article

Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?

Haass, Nikolas K. (2015). Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?. Melanoma Management, 2 (2), 93-95. doi: 10.2217/MMT.15.1

Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?

2015

Journal Article

Friends or foes: IL-10 and TGF-beta in melanoma

Tikoo, Shweta and Haass, Nikolas K. (2015). Friends or foes: IL-10 and TGF-beta in melanoma. Experimental Dermatology, 24 (4), 254-255. doi: 10.1111/exd.12661

Friends or foes: IL-10 and TGF-beta in melanoma

2015

Journal Article

Expression of Bcl-xL and Mcl-1 in the Nonmelanoma Skin Cancers of Renal Transplant Recipients

Burke, Michael T., Morais, Christudas, Oliver, Kimberley A., Lambie, Duncan L. J., Gobe, Glenda C., Carroll, Robert P., Staatz, Christine E., Sinnya, Sudipta, Soyer, H. Peter, Winterford, Clay, Haass, Nikolas K., Campbell, Scott B. and Isbel, Nicole M. (2015). Expression of Bcl-xL and Mcl-1 in the Nonmelanoma Skin Cancers of Renal Transplant Recipients. American Journal of Clinical Pathology, 143 (4), 514-526. doi: 10.1309/AJCPQNB5WA3PLQBK

Expression of Bcl-xL and Mcl-1 in the Nonmelanoma Skin Cancers of Renal Transplant Recipients

2015

Journal Article

Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.

Haass, Nikolas K., Nassif, Najah and McGowan, Eileen M. (2015). Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.. BioMed Research International, 2015 165105, 165105.1-165105.9. doi: 10.1155/2015/165105

Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.