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2023

Journal Article

Donor heart ischemic time can be extended to 8 hours using hypothermic machine perfusion in sheep

See Hoe, Louise E., Bassi, Gianluigi Li, Wildi, Karin, Passmore, Margaret R., Bouquet, Mahe, Sato, Kei, Heinsar, Silver, Ainola, Carmen, Bartnikowski, Nicole, Wilson, Emily S., Hyslop, Kieran, Skeggs, Kris, Obonyo, Nchafatso G., Shuker, Tristan, Bradbury, Lucy, Palmieri, Chiara, Pedersen, Sanne-Engkilde, McDonald, Charles, Colombo, Sebastiano M., Wells, Matthew A., Reid, Janice D., O'Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Haymet, Andrew, Jung, Jae-Seung, Sato, Noriko, James, Lynnette, He, Ting ... Fraser, John F. (2023). Donor heart ischemic time can be extended to 8 hours using hypothermic machine perfusion in sheep. The Journal of Heart and Lung Transplantation, 42 (8), 1015-1029. doi: 10.1016/j.healun.2023.03.020

Donor heart ischemic time can be extended to 8 hours using hypothermic machine perfusion in sheep

2023

Journal Article

Effects of transfusing older red blood cells and platelets on obstetric patient outcomes: a retrospective cohort study

Obonyo, Nchafatso G., Lu, Lawrence Y., White, Nicole M., Sela, Declan P., Rachakonda, Reema H., Teo, Derek, Tunbridge, Matthew, Sim, Beatrice, See Hoe, Louise E., Fanning, Jonathon P., Tung, John‐Paul, McKnoulty, Matthew, Bassi, Gianluigi Li, Suen, Jacky Y. and Fraser, John F. (2023). Effects of transfusing older red blood cells and platelets on obstetric patient outcomes: a retrospective cohort study. International Journal of Gynecology and Obstetrics, 164 (1), 184-191. doi: 10.1002/ijgo.14997

Effects of transfusing older red blood cells and platelets on obstetric patient outcomes: a retrospective cohort study

2023

Journal Article

Assessment and diagnosis of right ventricular failure—retrospection and future directions

Ro, Sun Kyun, Sato, Kei, Ijuin, Shinichi, Sela, Declan, Fior, Gabriele, Heinsar, Silver, Kim, Ji Young, Chan, Jonathan, Nonaka, Hideaki, Lin, Aaron C. W., Bassi, Gianluigi Li, Platts, David G., Obonyo, Nchafatso G., Suen, Jacky Y. and Fraser, John F. (2023). Assessment and diagnosis of right ventricular failure—retrospection and future directions. Frontiers in Cardiovascular Medicine, 10 1030864, 1-17. doi: 10.3389/fcvm.2023.1030864

Assessment and diagnosis of right ventricular failure—retrospection and future directions

2023

Journal Article

Interleukin-6 inhibitors in non-COVID-19 ARDS: analyzing the past to step into the post-COVID-19 era

Gandini, Lucia, Fior, Gabriele, Schibler, Andreas, Obonyo, Nchafatso G., Li Bassi, Gianluigi, Suen, Jacky Y. and Fraser, John F. (2023). Interleukin-6 inhibitors in non-COVID-19 ARDS: analyzing the past to step into the post-COVID-19 era. Critical Care, 27 (1) 124, 124. doi: 10.1186/s13054-023-04394-w

Interleukin-6 inhibitors in non-COVID-19 ARDS: analyzing the past to step into the post-COVID-19 era

2023

Journal Article

A novel speckle-tracking echocardiographic parameter considering left ventricular loading condition in cardiogenic shock during VA ECMO

Sato, Kei, Heinsar, Silver, Wildi, Karin Susanne, Obonyo, Nchafatso, LIU, KEIBUN, Farah, Samia, Ainola, Carmen, Sato, Noriko, Fior, Gabriele, Ro, Sun Kyun, Gandini, Lucia, Ijuin, Shinichi, Bouquet, Mahe, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Chan, Jonathan H., Platts, David, Suen, Jacky, Bassi, Gianluigi Li and Fraser, John (2023). A novel speckle-tracking echocardiographic parameter considering left ventricular loading condition in cardiogenic shock during VA ECMO. Journal of the American College of Cardiology, 81 (8) 1396, 1-1. doi: 10.1016/s0735-1097(23)01840-5

A novel speckle-tracking echocardiographic parameter considering left ventricular loading condition in cardiogenic shock during VA ECMO

2023

Journal Article

Hemorrhage, disseminated intravascular coagulopathy, and thrombosis complications among critically ill patients with COVID-19: an international COVID-19 critical care consortium study

Fanning, Jonathon P., Weaver, Natasha, Fanning, Robert B., Griffee, Matthew J., Cho, Sung-Min, Panigada, Mauro, Obonyo, Nchafatso G., Zaaqoq, Akram M., Rando, Hannah, Chia, Yew Woon, Fan, Bingwen Eugene, Sela, Declan, Chiumello, Davide, Coppola, Silvia, Labib, Ahmed, Whitman, Glenn J. R., Arora, Rakesh C., Kim, Bo S., Motos, Anna, Torres, Antoni, Barbé, Ferran, Grasselli, Giacomo, Zanella, Alberto, Etchill, Eric, Usman, Asad Ali, Feth, Maximilian, White, Nicole M., Suen, Jacky Y., Li Bassi, Gianluigi ... on behalf of the COVID-19 Critical Care Consortium (2023). Hemorrhage, disseminated intravascular coagulopathy, and thrombosis complications among critically ill patients with COVID-19: an international COVID-19 critical care consortium study. Critical Care Medicine, 51 (5), 619-631. doi: 10.1097/ccm.0000000000005798

Hemorrhage, disseminated intravascular coagulopathy, and thrombosis complications among critically ill patients with COVID-19: an international COVID-19 critical care consortium study

2023

Journal Article

Resuscitation Associated Endotheliopathy (PubMed)

Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation Associated Endotheliopathy (PubMed). searchRxiv, 2023. doi: 10.1079/searchrxiv.2023.00206

Resuscitation Associated Endotheliopathy (PubMed)

2022

Journal Article

A clinical and physiological prospective observational study on the management of pediatric shock in the post-fluid expansion as supportive therapy trial era

Obonyo, Nchafatso G., Olupot-Olupot, Peter, Mpoya, Ayub, Nteziyaremye, Julius, Chebet, Martin, Uyoga, Sophie, Muhindo, Rita, Fanning, Jonathon P., Shiino, Kenji, Chan, Jonathan, Fraser, John F. and Maitland, Kathryn (2022). A clinical and physiological prospective observational study on the management of pediatric shock in the post-fluid expansion as supportive therapy trial era. Pediatric Critical Care Medicine, 23 (7), 502-513. doi: 10.1097/pcc.0000000000002968

A clinical and physiological prospective observational study on the management of pediatric shock in the post-fluid expansion as supportive therapy trial era

2022

Journal Article

Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis

Li Bassi, Gianluigi, Gibbons, Kristen, Suen, Jacky Y., Dalton, Heidi J., White, Nicole, Corley, Amanda, Shrapnel, Sally, Hinton, Samuel, Forsyth, Simon, Laffey, John G., Fan, Eddy, Fanning, Jonathon P., Panigada, Mauro, Bartlett, Robert, Brodie, Daniel, Burrell, Aidan, Chiumello, Davide, Elhazmi, Alyaa, Esperatti, Mariano, Grasselli, Giacomo, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Marwali, Eva, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Ogino, Mark, Pelosi, Paolo ... The COVID-19 Critical Care Consortium (2022). Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis. Critical Care, 26 (1) 141, 141. doi: 10.1186/s13054-022-03983-5

Early short course of neuromuscular blocking agents in patients with COVID-19 ARDS: a propensity score analysis

2022

Journal Article

Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study

Urner, Martin, Barnett, Adrian G., Bassi, Gianluigi Li, Brodie, Daniel, Dalton, Heidi J., Ferguson, Niall D., Heinsar, Silver, Hodgson, Carol L., Peek, Giles, Shekar, Kiran, Suen, Jacky Y., Fraser, John F., Fan, Eddy, COVID-19 Critical Care Consortium Investigators and Obonyo, Nchafatso (2022). Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study. BMJ, 377 e068723, e068723. doi: 10.1136/bmj-2021-068723

Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study

2022

Journal Article

Exploration of the utility of speckle-tracking echocardiography during mechanical ventilation and mechanical circulatory support

Sato, Kei, Chan, Jonathan, Appadurai, Vinesh, Obonyo, Nchafatso, See Hoe, Louise, Suen, Jacky Y. and Fraser, John F. (2022). Exploration of the utility of speckle-tracking echocardiography during mechanical ventilation and mechanical circulatory support. Critical Care Explorations, 4 (4) e0666, 1-10. doi: 10.1097/CCE.0000000000000666

Exploration of the utility of speckle-tracking echocardiography during mechanical ventilation and mechanical circulatory support

2022

Journal Article

Impact of renin-angiotensin-aldosterone system inhibition on mortality in critically ill COVID-19 patients with pre-existing hypertension: a prospective cohort study

Sato, Kei, White, Nicole, Fanning, Jonathon P., Obonyo, Nchafatso, Yamashita, Michael H., Appadurai, Vinesh, Ciullo, Anna, May, Meryta, Worku, Elliott T., Helms, Leticia, Ohshimo, Shinichiro, Juzar, Dafsah A., Suen, Jacky Y., Bassi, Gianluigi Li, Fraser, John F., Arora, Rakesh C. and on behalf of COVID-19 Critical Care Consortium Investigators (2022). Impact of renin-angiotensin-aldosterone system inhibition on mortality in critically ill COVID-19 patients with pre-existing hypertension: a prospective cohort study. BMC Cardiovascular Disorders, 22 (1) 123, 123. doi: 10.1186/s12872-022-02565-1

Impact of renin-angiotensin-aldosterone system inhibition on mortality in critically ill COVID-19 patients with pre-existing hypertension: a prospective cohort study

2021

Journal Article

A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death

See Hoe, Louise E., Wildi, Karin, Obonyo, Nchafatso G., Bartnikowski, Nicole, McDonald, Charles, Sato, Kei, Heinsar, Silver, Engkilde-Pedersen, Sanne, Diab, Sara, Passmore, Margaret R., Wells, Matthew A., Boon, Ai-Ching, Esguerra, Arlanna, Platts, David G., James, Lynnette, Bouquet, Mahe, Hyslop, Kieran, Shuker, Tristan, Ainola, Carmen, Colombo, Sebastiano M., Wilson, Emily S., Millar, Jonathan E., Malfertheiner, Maximillian V., Reid, Janice D., O’Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Sato, Noriko, He, Ting ... Fraser, John F. (2021). A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death. Intensive Care Medicine Experimental, 9 (1) 60, 1-24. doi: 10.1186/s40635-021-00425-4

A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death

2021

Journal Article

Abstract 10482: Renin-Angiotensin-Aldosterone System Inhibition is Associated with Reduced In-Hospital Mortality in Critically Ill Covid-19 Patients with Pre-Existing Hypertension

Sato, Kei, White, Nicole, Fanning, Jonathon P, Obonyo, Nchafatso, Appadurai, Vinesh, Ciullo, Anna, May, Meryta, Worku, Elliott, Helms, Leticia, Ohshimo, Shinichiro, Yamashita, Michael, Suen, Jacky Y, Bassi, Gianluigi Li, Fraser, John F and ARORA, Rakesh C (2021). Abstract 10482: Renin-Angiotensin-Aldosterone System Inhibition is Associated with Reduced In-Hospital Mortality in Critically Ill Covid-19 Patients with Pre-Existing Hypertension. Circulation, 144 (Suppl_1). doi: 10.1161/circ.144.suppl_1.10482

Abstract 10482: Renin-Angiotensin-Aldosterone System Inhibition is Associated with Reduced In-Hospital Mortality in Critically Ill Covid-19 Patients with Pre-Existing Hypertension

2021

Journal Article

Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study

Li Bassi, Gianluigi, Suen, Jacky Y., White, Nicole, Dalton, Heidi J., Fanning, Jonathon, Corley, Amanda, Shrapnel, Sally, Hinton, Samuel, Forsyth, Simon, Parsons, Rex, Laffey, John G., Fan, Eddy, Bartlett, Robert, Brodie, Daniel, Burrell, Aidan, Chiumello, Davide, Elhazmi, Alyaa, Grasselli, Giacomo, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Marwali, Eva, Merson, Laura, Murthy, Srinivas, Nichol, Alistair, Panigada, Mauro, Pelosi, Paolo, Torres, Antoni, Ng, Pauline Yeung ... Obonyo, Nchafatso (2021). Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study. Critical Care Explorations, 3 (11) e0567, e0567. doi: 10.1097/cce.0000000000000567

Assessment of 28-day in-hospital mortality in mechanically ventilated patients with coronavirus disease 2019: an international cohort study

2021

Journal Article

Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model

Walweel, K., Boon, A. C., See Hoe, L. E., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Colombo, S. M., Bartnikowski, N. J., Bouquet, M., Wells, M. A., Black, D. M., Pimenta, L. P., Stevenson, A. K., Bisht, K., Skeggs, K., Marshall, L., Prabhu, A., James, L. N., Platts, D. G., Macdonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2021). Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model. Biomedical Journal, 45 (5), 776-787. doi: 10.1016/j.bj.2021.10.007

Brain stem death induces pro-inflammatory cytokine production and cardiac dysfunction in sheep model

2021

Journal Article

Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study

Millar, Jonathan E., Wildi, Karin, Bartnikowski, Nicole, Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Ki, Katrina K., See Hoe, Louise E., Obonyo, Nchafatso G., Neyton, Lucile, Pedersen, Sanne, Rozencwajg, Sacha, Baillie, J. Kenneth, Li Bassi, Gianluigi, Suen, Jacky Y., McAuley, Daniel F. and Fraser, John F. (2021). Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study. Physiological Reports, 9 (19) e15048, e15048. doi: 10.14814/phy2.15048

Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: an experimental ovine study

2021

Journal Article

Global infectious disease research collaborations in crises: building capacity and inclusivity through cooperation

Fanning, Jonathon P., Murthy, Srinivas, Obonyo, Nchafatso G., Baillie, J. Kenneth, Webb, Steve, Dalton, Heidi J. and Fraser, John F. (2021). Global infectious disease research collaborations in crises: building capacity and inclusivity through cooperation. Globalization and Health, 17 (1) 84, 1-6. doi: 10.1186/s12992-021-00731-2

Global infectious disease research collaborations in crises: building capacity and inclusivity through cooperation

2021

Journal Article

Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death

Wells, Matthew A., See Hoe, Louise E., Molenaar, Peter, Pedersen, Sanne, Obonyo, Nchafatso G., McDonald, Charles I., Mo, Weilan, Bouquet, Mahè, Hyslop, Kieran, Passmore, Margaret R., Bartnikowski, Nicole, Suen, Jacky Y., Peart, Jason N., McGiffin, David C., Fraser, John F. and on behalf of the Dead Heart Project (2021). Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death. Pharmacological Research, 169 105631, 1-12. doi: 10.1016/j.phrs.2021.105631

Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death

2021

Journal Article

An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients

Li Bassi, Gianluigi, Suen, Jacky Y, Dalton, Heidi J, White, Nicole, Shrapnel, Sally, Fanning, Jonathon P, Liquet, Benoit, Hinton, Samuel, Vuorinen, Aapeli, Booth, Gareth, Millar, Jonathan E, Forsyth, Simon, Panigada, Mauro, Laffey, John, Brodie, Daniel, Fan, Eddy, Torres, Antoni, Chiumello, Davide, Corley, Amanda, Elhazmi, Alyaa, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Murthy, Srinivas, Nichol, Alistair, Ng, Pauline Yeung, Ogino, Mark, Pesenti, Antonio, Trieu, Huynh Trung ... Obonyo, Gikenyi N. (2021). An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients. Critical Care, 25 (1) 199, 1-22. doi: 10.1186/s13054-021-03518-4

An appraisal of respiratory system compliance in mechanically ventilated covid-19 patients