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2021 Journal Article Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): a phase II randomised controlled trial: trial protocolMaitland, Kathryn, Olupot-Olupot, Peter, Aloroker, Florence, Mpoya, Ayub, Mnjalla, Hellen, Passi, George, Nakuya, Margaret, Houston, Kirsty, Obonyo, Nchafatso, Hamaluba, Mainga, Evans, Jennifer A, Connon, Roisin, George, Elizabeth C and Gibb, Diana M (2021). Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): a phase II randomised controlled trial: trial protocol. Wellcome Open Research, 6 160, 160. doi: 10.12688/wellcomeopenres.16885.1 |
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2020 Journal Article Characterising pre-clinical sub-phenotypic models of Acute Respiratory Distress Syndrome: an experimental ovine studyMillar, Jonathan E., Wildi, Karin, Bartnikowski, Nicole, Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Ki, Katrina K., See Hoe, Louise E., Obonyo, Nchafatso G., Neyton, Lucile, Pedersen, Sanne, Rozencwajg, Sacha, Baillie, J. Kenneth, Li Bassi, Gianluigi, Suen, Jacky Y, McAuley, Daniel F. and Fraser, John F. (2020). Characterising pre-clinical sub-phenotypic models of Acute Respiratory Distress Syndrome: an experimental ovine study. |
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2020 Journal Article Microvascular dysfunction in septic and dengue shock: pathophysiology and implications for clinical managementMcBride, Angela, Chanh, Ho Q., Fraser, John F., Yacoub, Sophie and Obonyo, Nchafatso G. (2020). Microvascular dysfunction in septic and dengue shock: pathophysiology and implications for clinical management. Global Cardiology Science and Practice, 2020 (2) e202029, e202029. doi: 10.21542/gcsp.2020.29 |
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2020 Journal Article Heart transplantation from brain dead donors: a systematic review of animal modelsSee Hoe, Louise E., Wells, Matthew A., Bartnikowski, Nicole, Obonyo, Nchafatso G., Millar, Jonathan E., Khoo, Aimee, Ki, Katrina K., Shuker, Tristan, Ferraioli, Alessandro, Colombo, Sebastiano M., Chan, Wandy, McGiffin, David C., Suen, Jacky Y. and Fraser, John F. (2020). Heart transplantation from brain dead donors: a systematic review of animal models. Transplantation, 104 (11), 2272-2289. doi: 10.1097/tp.0000000000003217 |
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2020 Journal Article Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion systemWalweel, K., Skeggs, K., Boon, A. C., See Hoe, L. E., Bouquet, M., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Wood, E. S., Reid, J., Colombo, S. M., Bartnikowski, N. J., Wells, M. A., Black, D., Pimenta, L. P., Stevenson, A. K., Bisht, K., Marshall, L., Prabhu, D. A., James, L., Platts, D. G., MacDonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2020). Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system. Journal of Biomedical Science, 27 (1) 96, 96. doi: 10.1186/s12929-020-00690-7 |
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2020 Journal Article Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheepMillar, Jonathan E., Bartnikowski, Nicole, Passmore, Margaret R., Obonyo, Nchafatso G, Malfertheiner, Maximillian V., von Bahr, Viktor, Redd, Meredith A., See Hoe, Louise, Ki, Katrina K., Pedersen, Sanne, Boyle, Andrew J., Baillie, J Kenneth, Shekar, Kiran, Palpant, Nathan, Suen, Jacky Y., Matthay, Michael A., McAuley, Daniel F., Fraser, John F. and Combining Extracorporeal Life Support and Cell Therapy in Critical Illness (CELTIC) investigators (2020). Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep. American Journal of Respiratory and Critical Care Medicine, 202 (3) rccm.201911-2143OC, 383-392. doi: 10.1164/rccm.201911-2143oc |
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2020 Journal Article Corrigendum: Sepsis: changing definitions, unchanging treatment (vol 6, 425, 2019)Obonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2020). Corrigendum: Sepsis: changing definitions, unchanging treatment (vol 6, 425, 2019). Frontiers in Pediatrics, 7 538, 538. doi: 10.3389/fped.2019.00538 |
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2019 Journal Article Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydrationHouston, Kirsty A., Gibb, Jack, Olupot-Olupot, Peter, Obonyo, Nchafatso, Mpoya, Ayub, Nakuya, Margaret, Muhindo, Rita, Uyoga, Sophie, Evans, Jennifer A., Connon, Roisin, Gibb, Diana M., George, Elizabeth C. and Maitland, Kathryn (2019). Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration. BMC Medicine, 17 (1) 122. doi: 10.1186/s12916-019-1356-z |
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2019 Journal Article Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shockPassmore, Margaret R., Obonyo, Nchafatso G., Byrne, Liam, Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Fung, Yoke L., Spanevello, Michelle M., Fauzi, Mohd H., Pedersen, Sanne E., Simonova, Gabriela, Anstey, Chris M., Shekar, Kiran, Tung, John-Paul, Maitland, Kathryn and Fraser, John F. (2019). Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock. Thrombosis Research, 176, 39-45. doi: 10.1016/j.thromres.2019.02.015 |
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2019 Journal Article Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical modelsMillar, Jonathan E., Bartnikowski, Nicole, von Bahr, Viktor, Malfertheiner, Maximilian V., Obonyo, Nchafatso G., Belliato, Mirko, Suen, Jacky Y., Combes, Alain, McAuley, Daniel F., Lorusso, Roberto and Fraser, John F. (2019). Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models. Intensive Care Medicine Experimental, 7 (1) 18, 18. doi: 10.1186/s40635-019-0232-7 |
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2019 Journal Article Assessment of myocardial function in Kenyan children with severe, acute malnutrition the Cardiac Physiology in Malnutrition (CAPMAL) StudyBrent, Bernadette, Obonyo, Nchafatso, Akech, Samuel, Shebbe, Mohammed, Mpoya, Ayub, Mturi, Neema, Berkley, James A., Tulloh, Robert M. R. and Maitland, Kathryn (2019). Assessment of myocardial function in Kenyan children with severe, acute malnutrition the Cardiac Physiology in Malnutrition (CAPMAL) Study. JAMA Network Open, 2 (3). doi: 10.1001/jamanetworkopen.2019.1054 |
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2019 Journal Article Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantationFanning, Jonathon P., Hoe, Louise E. See, Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky Y. and Fraser, John F. (2019). Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation. The American Journal of Cardiology, 123 (3), 434-439. doi: 10.1016/j.amjcard.2018.10.022 |
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2019 Journal Article Sepsis: changing definitions, unchanging treatmentObonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2019). Sepsis: changing definitions, unchanging treatment. Frontiers in Pediatrics, 6 (JAN) 425, 425. doi: 10.3389/fped.2018.00425 |
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2019 Journal Article Pre-clinical study protocol: Blood transfusion in endotoxaemic shockObonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005 |
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2018 Journal Article Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shockPassmore, Margaret R., Byrne, Liam, Obonyo, Nchafatso G., See Hoe, Louise E., Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Bisht, Kavita, Tung, John-Paul, Fauzi, Mohd H., Narula, Monica, Pedersen, Sanne E., Esguerra-Lallen, Arlanna, Simonova, Gabriela, Sultana, Annette, Anstey, Chris M., Shekar, Kiran, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2018). Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock. Respiratory Research, 19 (1) 231, 231. doi: 10.1186/s12931-018-0935-4 |
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2018 Journal Article Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemiaByrne, Liam, Obonyo, Nchafatso G., Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Pedersen, Sanne, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Van Haren, Frank, Anstey, Christopher M., Cullen, Louise, Tung, John-Paul, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia. American Journal of Respiratory and Critical Care Medicine, 198 (8), 1043-1054. doi: 10.1164/rccm.201801-0064OC |
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2018 Journal Article An ovine model of hyperdynamic endotoxemia and vital organ metabolismByrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904 |
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2017 Journal Article Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literatureMalfertheiner, M. V., Pimenta, L. P., Von Bahr, V., Millar, J. E., Obonyo, N. G., Suen, J. Y., Pellegrino, V. and Fraser, J. F. (2017). Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature. Critical Care and Resuscitation, 19, 45-52. |
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2017 Journal Article Gastroenteritis Aggressive Versus Slow Treatment For Rehydration (GASTRO). A pilot rehydration study for severe dehydration: WHO plan C versus slower rehydrationHouston, Kirsty A., Gibb, Jack G., Mpoya, Ayub, Obonyo, Nchafatso, Olupot-Olupot, Peter, Nakuya, Margeret, Evans, Jennifer A., George, Elizabeth C., Gibb, Diana M. and Maitland, Kathryn (2017). Gastroenteritis Aggressive Versus Slow Treatment For Rehydration (GASTRO). A pilot rehydration study for severe dehydration: WHO plan C versus slower rehydration. Wellcome Open Research, 2 62, 62. doi: 10.12688/wellcomeopenres.12261.1 |
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2017 Journal Article Left Ventricular Global Strain Analysis by Two-Dimensional Speckle-Tracking Echocardiography: The Learning CurveChan, Jonathan, Shiino, Kenji, Obonyo, Nchafatso G., Hanna, Joseph, Chamberlain, Robert, Small, Andrew, Scalia, Isabel G., Scalia, William, Yamada, Akira, Hamilton-Craig, Christian R., Scalia, Gregory M. and Zamorano, Jose Luis (2017). Left Ventricular Global Strain Analysis by Two-Dimensional Speckle-Tracking Echocardiography: The Learning Curve. Journal of the American Society of Echocardiography, 30 (11), 1081-1090. doi: 10.1016/j.echo.2017.06.010 |
