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2025

Journal Article

Effects of transfusing older red blood cells on patient outcomes in critical illness: A retrospective cohort study

Obonyo, Nchafatso G., Sela, Declan P., White, Nicole, Tunbridge, Matthew, Sim, Beatrice, Rachakonda, Reema H., See Hoe, Louise E., Li Bassi, Gianluigi, Fanning, Jonathon P., Tung, John‐Paul, Suen, Jacky Y. and Fraser, John F. (2025). Effects of transfusing older red blood cells on patient outcomes in critical illness: A retrospective cohort study. Vox Sanguinis. doi: 10.1111/vox.70007

Effects of transfusing older red blood cells on patient outcomes in critical illness: A retrospective cohort study

2024

Journal Article

Early myocardial injury in children on doxorubicin for cancer chemotherapy: a cross-sectional study in a tertiary referral centre in Kenya

Kariuki, Nyambura, Kimani, Esther, Jowi, Christine, Wamalwa, Dalton, Suen, Jacky Y., Fraser, John F. and Obonyo, Nchafatso G. (2024). Early myocardial injury in children on doxorubicin for cancer chemotherapy: a cross-sectional study in a tertiary referral centre in Kenya. BMC Cardiovascular Disorders, 24 (1) 260, 1-9. doi: 10.1186/s12872-024-03922-y

Early myocardial injury in children on doxorubicin for cancer chemotherapy: a cross-sectional study in a tertiary referral centre in Kenya

2024

Journal Article

Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation

Karnik, Varun, Colombo, Sebastiano Maria, Rickards, Leah, Heinsar, Silver, See Hoe, Louise E., Wildi, Karin, Passmore, Margaret R., Bouquet, Mahe, Sato, Kei, Ainola, Carmen, Bartnikowski, Nicole, Wilson, Emily S., Hyslop, Kieran, Skeggs, Kris, Obonyo, Nchafatso G., McDonald, Charles, Livingstone, Samantha, Abbate, Gabriella, Haymet, Andrew, Jung, Jae-Seung, Sato, Noriko, James, Lynnette, Lloyd, Benjamin, White, Nicole, Palmieri, Chiara, Buckland, Mark, Suen, Jacky Y., McGiffin, David C., Fraser, John F. and Li Bassi, Gianluigi (2024). Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation. Intensive Care Medicine Experimental, 12 (1) 109. doi: 10.1186/s40635-024-00669-w

Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation

2024

Journal Article

An ovine septic shock model of live bacterial infusion

Obonyo, Nchafatso G., Raman, Sainath, Suen, Jacky Y., Peters, Kate M., Phan, Minh-Duy, Passmore, Margaret R., Bouquet, Mahe, Wilson, Emily S., Hyslop, Kieran, Palmieri, Chiara, White, Nicole, Sato, Kei, Farah, Samia M., Gandini, Lucia, Liu, Keibun, Fior, Gabriele, Heinsar, Silver, Ijuin, Shinichi, Kyun Ro, Sun, Abbate, Gabriella, Ainola, Carmen, Sato, Noriko, Lundon, Brooke, Portatadino, Sofia, Rachakonda, Reema H., Schneider, Bailey, Harley, Amanda, See Hoe, Louise E., Schembri, Mark A. ... Fraser, John F. (2024). An ovine septic shock model of live bacterial infusion. Intensive Care Medicine Experimental, 12 (1) 94, 1-20. doi: 10.1186/s40635-024-00684-x

An ovine septic shock model of live bacterial infusion

2024

Journal Article

Echocardiographic surrogate of left ventricular stroke work in a model of brain stem death donors

Sato, Kei, See Hoe, Louise, Chan, Jonathan, Obonyo, Nchafatso G., Wildi, Karin, Heinsar, Silver, Colombo, Sebastiano M., Ainola, Carmen, Abbate, Gabriella, Sato, Noriko, Passmore, Margaret R., Bouquet, Mahe, Wilson, Emily S., Hyslop, Kieran, Livingstone, Samantha, Haymet, Andrew, Jung, Jae‐Seung, Skeggs, Kris, Palmieri, Chiara, White, Nicole, Platts, David, Suen, Jacky Y., McGiffin, David C., Li Bassi, Gianluigi and Fraser, John F. (2024). Echocardiographic surrogate of left ventricular stroke work in a model of brain stem death donors. European Journal of Clinical Investigation, 54 (10) e14259, 1-11. doi: 10.1111/eci.14259

Echocardiographic surrogate of left ventricular stroke work in a model of brain stem death donors

2024

Journal Article

A novel echocardiographic parameter considering left ventricular afterload during V‐A ECMO support

Sato, Kei, Heinsar, Silver, Chan, Jonathan, Farah, Samia M., Wildi, Karin, Obonyo, Nchafatso G., Liu, Keibun, Ainola, Carmen, Sato, Noriko, Abbate, Gabriella, Wilson, Emily S., Bouquet, Mahé, Hyslop, Kieran, Passmore, Margaret R., Ijuin, Shinichi, Ro, Sun Kyun, Fior, Gabriele, Gandini, Lucia, Lundon, Brooke, Platts, David G., Suen, Jacky Y., Li Bassi, Gianluigi and Fraser, John F. (2024). A novel echocardiographic parameter considering left ventricular afterload during V‐A ECMO support. European Journal of Clinical Investigation, 54 (10) e14263, 1-11. doi: 10.1111/eci.14263

A novel echocardiographic parameter considering left ventricular afterload during V‐A ECMO support

2024

Journal Article

SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART)

Maitland, Kathryn, Hamaluba, Mainga, Obonyo, Nchafatso, Oguda, Emmanuel, Mogoka, Christabel, Williams, Thomas N., Chaponda, Mike, Miti, Sam, Kamavu, Luc Kambale, Jonathan Gwasupika, Jonathan, Connon, Roisin, Gibb, Diana M., Dondorp, Arjen, Day, Nick, White, Nick, Walker, A. Sarah, George, Elizabeth C. and Severe Malaria in African Children A Research and Trials (SMAART) consortium (2024). SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART). Wellcome Open Research, 8 484, 484. doi: 10.12688/wellcomeopenres.20111.2

SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART)

2024

Journal Article

Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study

Obonyo, Nchafatso. G., Dhanapathy, Vikash, White, Nicole, Sela, Declan P., Rachakonda, Reema H., Tunbridge, Matthew, Sim, Beatrice, Teo, Derek, Nadeem, Zohaib, See Hoe, Louise E., Bassi, Gianluigi Li, Fanning, Jonathon P., Tung, John-Paul, Suen, Jacky Y. and Fraser, John F. (2024). Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study. Journal of Cardiothoracic Surgery, 19 (1) 475. doi: 10.1186/s13019-024-02974-7

Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study

2024

Journal Article

Current trends and latest developments in echocardiographic assessment of right ventricular function: load dependency perspective

Nonaka, Hideaki, Rätsep, Indrek, Obonyo, Nchafatso G., Suen, Jacky Y., Fraser, John F. and Chan, Jonathan (2024). Current trends and latest developments in echocardiographic assessment of right ventricular function: load dependency perspective. Frontiers in Cardiovascular Medicine, 11 1365798, 1-15. doi: 10.3389/fcvm.2024.1365798

Current trends and latest developments in echocardiographic assessment of right ventricular function: load dependency perspective

2024

Journal Article

Joint EASPS-AAPS Conference in Tanzania 2023: a beginning of the pragmatic efforts to promote physiology education, research and practice in East Africa

Alagbonsi, Abdullateef Isiaka, Essop, Faadiel, Njelekela, Marina, Leminie, Abebaye Aragaw, Ojiambo, Robert, Malindisa, Evangelista Kenan, Alkizim, Faraj Omar, Ninsiima, Herbert Izo, Kediso, Teketel Eristu, Mashili, Fredirick L., Chillo, Omary, Ebrahim, Ashabilan A., Dionis, Ikunda, Ruhighira, Jacktan Josephat and Obonyo, Nchafatso Gikenyi (2024). Joint EASPS-AAPS Conference in Tanzania 2023: a beginning of the pragmatic efforts to promote physiology education, research and practice in East Africa. Advances in Physiology Education, 48 (3), 573-577. doi: 10.1152/advan.00091.2024

Joint EASPS-AAPS Conference in Tanzania 2023: a beginning of the pragmatic efforts to promote physiology education, research and practice in East Africa

2024

Journal Article

A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial)

Maitland, Kathryn, Obonyo, Nchafasto, Hamaluba, Mainga, Ogoda, Emmanuel, Mogaka, Christabel, Williams, Thomas N., Newton, Charles, Kariuki, Symon M., Gibb, Diana M., Walker, A. Sarah, Connon, Roisin and George, Elizabeth C. (2024). A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial). Wellcome Open Research, 9 281. doi: 10.12688/wellcomeopenres.21403.1

A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial)

2024

Journal Article

Comparative analysis of novel esophageal pressure monitoring catheters versus commercially available alternatives in a biomechanical model of the thoracic cavity

Abbate, Gabriella, Colombo, Sebastiano Maria, Semenzin, Clayton, Sato, Noriko, Liu, Keibun, Ainola, Carmen, Milani, Angelo, Fior, Gabriele, Obonyo, Nchafatso, White, Nicole, Chiumello, Davide, Pauls, Jo, Suen, Jacky Y., Fraser, John F. and Li Bassi, Gianluigi (2024). Comparative analysis of novel esophageal pressure monitoring catheters versus commercially available alternatives in a biomechanical model of the thoracic cavity. Scientific Reports, 14 (1) 9771, 1-12. doi: 10.1038/s41598-024-59790-1

Comparative analysis of novel esophageal pressure monitoring catheters versus commercially available alternatives in a biomechanical model of the thoracic cavity

2024

Journal Article

Improved microcirculation with pulsatile veno-arterial ECMO: an ovine model of cardiogenic shock

Heinsar, Silver, Sato, Kei, Obonyo, Nchafatso, Farah, Samia M, Bouquet, Mahe, Passmore, Margaret R, Liu, Keibun, Ijunin, Shinichi, Ainola, Carmen, Li Bassi, Gianluigi, Suen, Jacky Y and Fraser, John F. (2024). Improved microcirculation with pulsatile veno-arterial ECMO: an ovine model of cardiogenic shock. American Journal of Respiratory and Critical Care Medicine, 209 (11), 1396-1399. doi: 10.1164/rccm.202402-0419le

Improved microcirculation with pulsatile veno-arterial ECMO: an ovine model of cardiogenic shock

2024

Journal Article

Catalysing global surgery: a meta-research study on factors affecting surgical research collaborations with Africa

Kirengo, Thomas O., Dossajee, Hussein, Onyango, Evans M., Rachakonda, Reema H., Schneider, Bailey, Sela, Declan P., Hosseinzadeh, Zahra, Nadeem, Zohaib and Obonyo, Nchafatso G. (2024). Catalysing global surgery: a meta-research study on factors affecting surgical research collaborations with Africa. Systematic Reviews, 13 (1) 89, 1-17. doi: 10.1186/s13643-024-02474-8

Catalysing global surgery: a meta-research study on factors affecting surgical research collaborations with Africa

2024

Journal Article

A novel speckle‐tracking echocardiography parameter assessing left ventricular afterload

Sato, Kei, Wildi, Karin, Chan, Jonathan, Palmieri, Chiara, Obonyo, Nchafatso G., Heinsar, Silver, Liu, Keibun, Livingstone, Samantha, Sato, Noriko, Ainola, Carmen, Abbate, Gabriella, Bouquet, Mahé, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Platts, David G., Suen, Jacky, Bassi, Gianluigi Li and Fraser, John F. (2024). A novel speckle‐tracking echocardiography parameter assessing left ventricular afterload. European Journal of Clinical Investigation, 54 (2) e14106, 1-12. doi: 10.1111/eci.14106

A novel speckle‐tracking echocardiography parameter assessing left ventricular afterload

2024

Journal Article

Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol

Olupot-Olupot, Peter, Aloroker, Florence, Mpoya, Ayub, Mnjalla, Hellen, Paasi, George, Nakuya, Margaret, Houston, Kirsty, Obonyo, Nchafatso, Hamaluba, Mainga, Evans, Jennifer A, Dewez, Manuel, Atti, Salifou, Guindo, Ousmane, Ouattara, San Maurice, Chara, Abdullahi, Sainna, Hadiza Alhaji, Amos, Omokore Oluseyi, Ogundipe, Oluwakemi, Sunyoto, Temmy, Coldiron, Matthew, LANGENDORF, Celine, SCHERRER, Marie-Francoise, PETRUCCI, Roberta, Connon, Roisin, George, Elizabeth C., Gibb, Diana M. and Maitland, Kathryn (2024). Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol. Wellcome Open Research, 6 160, 1-18. doi: 10.12688/wellcomeopenres.16885.2

Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol

2023

Journal Article

Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis

Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis. Systematic Reviews, 12 (1) 221, 1-17. doi: 10.1186/s13643-023-02385-0

Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis

2023

Journal Article

Cardiovascular Health Priorities in Sub-Saharan Africa

Obonyo, Nchafatso G. and Etyang, Anthony O. (2023). Cardiovascular Health Priorities in Sub-Saharan Africa. SN Comprehensive Clinical Medicine, 5 (1) 262. doi: 10.1007/s42399-023-01605-x

Cardiovascular Health Priorities in Sub-Saharan Africa

2023

Journal Article

The effects of nitric oxide on coagulation and inflammation in ex‐vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass

Malfertheiner, Maximilian V., Ashlen, Garrett, Margaret, Passmore, Haymet, Andrew B., Richard, Webb I., von Bahr, Viktor, Millar, Jonathan E., Schneider, Bailey A., Obonyo, Nchafatso G., Debra, Black, Mahe, Bouquet, Nicole, Bartnikowski, Suen, Jacky Y. and Fraser, John F. (2023). The effects of nitric oxide on coagulation and inflammation in ex‐vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass. Artificial Organs, 47 (10), 1581-1591. doi: 10.1111/aor.14608

The effects of nitric oxide on coagulation and inflammation in ex‐vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass

2023

Journal Article

SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART)

Maitland, Kathryn, Hamaluba, Mainga, Obonyo, Nchafatso, Oguda, Emmanuel, Mogoka, Christabel, Williams, Thomas N., Chaponda, Mike, Miti, Sam, Kamavu, Luc Kambale, Connon, Roisin, Gibb, Diana M., Dondorp, Arjen, Day, Nick, White, Nick, Walker, A. Sarah, George, Elizabeth C. and Severe Malaria in African Children A Research and Trials (SMAART) consortium (2023). SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART). Wellcome Open Research, 8, 484. doi: 10.12688/wellcomeopenres.20111.1

SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART)