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2014

Journal Article

Targeting angiotensin II type 2 receptor pathways to treat neuropathic pain and inflammatory pain

Smith, Maree T. and Muralidharan, Arjun (2014). Targeting angiotensin II type 2 receptor pathways to treat neuropathic pain and inflammatory pain. Expert Opinion On Therapeutic Targets, 19 (1), 25-35. doi: 10.1517/14728222.2014.957673

Targeting angiotensin II type 2 receptor pathways to treat neuropathic pain and inflammatory pain

2014

Journal Article

Comparative studies using the Morris water maze to assess spatial memory deficits in two transgenic mouse models Of Alzheimer's disease

Edwards, Stephen R., Hamlin, Adam S., Marks, Nicola, Coulson, Elizabeth J. and Smith, Maree T. (2014). Comparative studies using the Morris water maze to assess spatial memory deficits in two transgenic mouse models Of Alzheimer's disease. Clinical and Experimental Pharmacology and Physiology, 41 (10), 798-806. doi: 10.1111/1440-1681.12277

Comparative studies using the Morris water maze to assess spatial memory deficits in two transgenic mouse models Of Alzheimer's disease

2014

Journal Article

Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review

Kuo, Andy and Smith, Maree T. (2014). Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review. Journal of Neuroscience Methods, 233, 166-171. doi: 10.1016/j.jneumeth.2014.06.006

Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review

2014

Journal Article

Endomorphin analogues with mixed mu-opioid (MOP) receptor agonism/delta-opioid (DOP) receptor antagonism and lacking beta-arrestin2 recruitment activity

Cai, Jun, Song, Bowen, Cai, Yunxin, Ma, Yu, Lam, Ai-leen, Magiera, Julia, Sekar, Sunder, Wyse, Bruce D., Ambo, Akihiro, Sasaki, Yusuke, Lazarus, Lawrence H., Smith, Maree T. and Li, Tingyou (2014). Endomorphin analogues with mixed mu-opioid (MOP) receptor agonism/delta-opioid (DOP) receptor antagonism and lacking beta-arrestin2 recruitment activity. Biorganic and Medicinal Chemistry, 22 (7), 2208-2219. doi: 10.1016/j.bmc.2014.02.015

Endomorphin analogues with mixed mu-opioid (MOP) receptor agonism/delta-opioid (DOP) receptor antagonism and lacking beta-arrestin2 recruitment activity

2014

Journal Article

Analgesic efficacy of small-molecule angiotensin II type 2 receptor antagonists in a rat model of antiretroviral toxic polyneuropathy

Smith, Maree T., Lau, Tanya, Wallace, Victoria C. J., Wyse, Bruce D. and Rice, Andrew S. C. (2014). Analgesic efficacy of small-molecule angiotensin II type 2 receptor antagonists in a rat model of antiretroviral toxic polyneuropathy. Behavioural Pharmacology, 25 (2), 137-146. doi: 10.1097/FBP.0000000000000025

Analgesic efficacy of small-molecule angiotensin II type 2 receptor antagonists in a rat model of antiretroviral toxic polyneuropathy

2014

Journal Article

In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile

Kuo, A., Wyse, B. D., Meutermans, W. and Smith, M. T. (2014). In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile. British Journal of Pharmacology, Accepted Article (2), 1-48. doi: 10.1111/bph.12696

In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile

2014

Journal Article

Analgesic efficacy and mode of action of a selective small molecule angiotensin II type 2 receptor antagonist in a rat model of prostate cancer-induced bone pain

Muralidharan, Arjun, Wyse, Bruce D. and Smith, Maree T. (2014). Analgesic efficacy and mode of action of a selective small molecule angiotensin II type 2 receptor antagonist in a rat model of prostate cancer-induced bone pain. Pain Medicine, 15 (1), 93-110. doi: 10.1111/pme.12258

Analgesic efficacy and mode of action of a selective small molecule angiotensin II type 2 receptor antagonist in a rat model of prostate cancer-induced bone pain

2014

Journal Article

Current developments in MRI for assessing rodent models of multiple sclerosis

Alomair, Othman I., Smith, Maree T., Brereton, Ian M., Galloway, Graham J. and Kurniawan, Nyoman D. (2014). Current developments in MRI for assessing rodent models of multiple sclerosis. Future Neurology, 9 (4), 487-511. doi: 10.2217/FNL.14.33

Current developments in MRI for assessing rodent models of multiple sclerosis

2013

Journal Article

Pathobiology of cancer chemotherapy-induced peripheral neuropathy (CIPN)

Han, Yaqin and Smith, Maree T. (2013). Pathobiology of cancer chemotherapy-induced peripheral neuropathy (CIPN). Frontiers in Pharmacology, 4 Article 156, 1-16. doi: 10.3389/fphar.2013.00156

Pathobiology of cancer chemotherapy-induced peripheral neuropathy (CIPN)

2013

Journal Article

Multiple sclerosis-induced neuropathic pain: pharmacological management and pathophysiological insights from rodent EAE models

Khan, Nemat and Smith, Maree T. (2013). Multiple sclerosis-induced neuropathic pain: pharmacological management and pathophysiological insights from rodent EAE models. Inflammopharmacology, 22 (1), 1-22. doi: 10.1007/s10787-013-0195-3

Multiple sclerosis-induced neuropathic pain: pharmacological management and pathophysiological insights from rodent EAE models

2013

Journal Article

Comment On "protective Arms of the Renin-Angiotensin System in Neurological Disease"

Smith, Maree T. and Muralidharan, Arjun (2013). Comment On "protective Arms of the Renin-Angiotensin System in Neurological Disease". Clinical and Experimental Pharmacology and Physiology, 40 (11), 838-838. doi: 10.1111/1440-1681.12169

Comment On "protective Arms of the Renin-Angiotensin System in Neurological Disease"

2013

Journal Article

Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments

Muralidharan, Arjun and Smith, Maree T. (2013). Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments. Inflammopharmacology, 21 (5), 339-363. doi: 10.1007/s10787-013-0183-7

Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments

2013

Journal Article

A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia

Smith, Maree T., Woodruff, Trent M., Wyse, Bruce D., Muralidharan, Arjun and Walther, Thomas (2013). A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia. Pain Medicine, 14 (10), 1557-1568. doi: 10.1111/pme.12157

A small molecule angiotensin II type 2 receptor (AT2R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 Mitogen-Activated Protein Kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia

2013

Journal Article

Small molecule angiotensin II type 2 receptor (AT2R) antagonists as novel analgesics for neuropathic pain: comparative pharmacokinetics, radioligand binding, and efficacy in rats

Smith, Maree T., Wyse, Bruce D. and Edwards, Stephen R. (2013). Small molecule angiotensin II type 2 receptor (AT2R) antagonists as novel analgesics for neuropathic pain: comparative pharmacokinetics, radioligand binding, and efficacy in rats. Pain Medicine, 14 (5), 692-705. doi: 10.1111/pme.12063

Small molecule angiotensin II type 2 receptor (AT2R) antagonists as novel analgesics for neuropathic pain: comparative pharmacokinetics, radioligand binding, and efficacy in rats

2013

Journal Article

Peripherally acting novel lipo-endomorphin-1 peptides in neuropathic pain without producing constipation

Varamini, Pegah, Goh, Wei Huang, Mansfeld, Friederike M., Blanchfield, Joanne T., Wyse, Bruce D., Smith, Maree T. and Toth, Istvan (2013). Peripherally acting novel lipo-endomorphin-1 peptides in neuropathic pain without producing constipation. Bioorganic & Medicinal Chemistry, 21 (7), 1898-1904. doi: 10.1016/j.bmc.2013.01.044

Peripherally acting novel lipo-endomorphin-1 peptides in neuropathic pain without producing constipation

2013

Journal Article

The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

Shekar, Kiran, Roberts, Jason A., Smith, Maree T., Fung, Yoke L. and Fraser, John F. (2013). The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation. BMC Anesthesiology, 13 (1) 7, 7.1-7.10. doi: 10.1186/1471-2253-13-7

The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

2013

Journal Article

Optimization and characterization of a rat model of prostate cancer-induced bone pain using behavioural, pharmacological, radiological, histological and immunohistochemical methods

Muralidharan, Arjun, Wyse, Bruce D. and Smith, Maree T. (2013). Optimization and characterization of a rat model of prostate cancer-induced bone pain using behavioural, pharmacological, radiological, histological and immunohistochemical methods. Pharmacology Biochemistry and Behavior, 106, 33-46. doi: 10.1016/j.pbb.2013.02.020

Optimization and characterization of a rat model of prostate cancer-induced bone pain using behavioural, pharmacological, radiological, histological and immunohistochemical methods

2012

Journal Article

The erythropoietin-derived peptide ARA290 reverses mechanical allodynia in the neuritis model

Pulman, K. G. T., Smith, M., Mengozzi, M., Ghezzi, P. and Dilley, A. (2012). The erythropoietin-derived peptide ARA290 reverses mechanical allodynia in the neuritis model. Neuroscience, 233, 174-183. doi: 10.1016/j.neuroscience.2012.12.022

The erythropoietin-derived peptide ARA290 reverses mechanical allodynia in the neuritis model

2012

Journal Article

ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMO

Shekar, Kiran, Roberts, Jason A., Welsh, Susan, Buscher, Hergen, Rudham, Sam, Burrows, Fay, Ghassabian, Sussan, Wallis, Steven C., Levkovich, Bianca, Pellegrino, Vin, McGuiness, Shay, Parke, Rachael, Gilder, Eileen, Barnett, Adrian G., Walsham, James, Mullany, Daniel V., Fung, Yoke L., Smith, Maree T. and Fraser, John F. (2012). ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMO. BMC Anesthesiology, 12 (1) 29, 29.1-29.9. doi: 10.1186/1471-2253-12-29

ASAP ECMO: antibiotic, sedative and analgesic pharmacokinetics during extracorporeal membrane oxygenation: a multi-centre study to optimise drug therapy during ECMO

2012

Journal Article

Sedation during extracorporeal membrane oxygenation-why more is less

Shekar, K., Roberts, J. A., Ghassabian, S., Mullany, D. V., Ziegenfuss, M., Smith, M. T., Fung, Y. L. and Fraser, J. F. (2012). Sedation during extracorporeal membrane oxygenation-why more is less. Anaesthesia and Intensive Care, 40 (6), 1067-1069.

Sedation during extracorporeal membrane oxygenation-why more is less