2003 Journal Article Morphine-3-glucuronide's neuro-excitatory effects are mediated via indirect activation of N-methyl-D-aspartic acid receptors: Mechanistic studies in embryonic cultured hippocampal neuronesHemstapat, K., Monteith, G. R., Smith, D. and Smith, M. T. (2003). Morphine-3-glucuronide's neuro-excitatory effects are mediated via indirect activation of N-methyl-D-aspartic acid receptors: Mechanistic studies in embryonic cultured hippocampal neurones. Anesthesia & Analgesia, 97 (2), 494-505. doi: 10.1213/01.ANE.0000059225.40049.99 |
2003 Journal Article Managing diabetic neuropathySmith, M. T. (2003). Managing diabetic neuropathy. Australian Pharmacist, 22 (10), 782-787. |
2003 Journal Article The streptozotocin-diabetic rat as a model of the chronic complications of human diabetesWei, M., Ong, L., Smith, M. T., Ross, F. B., Schmid, K., Hoey, A., Burstow, D. J. and Brown, L. C. (2003). The streptozotocin-diabetic rat as a model of the chronic complications of human diabetes. Heart, Lung and Circulation, 2003 (12), 44-50. doi: 10.1046/j.1444-2892.2003.00160.x |
2003 Journal Article The neuroexcitatory morphine metabolite, morphine-3-glucuronide (M3G), is not neurotoxic in primary cultures of either hippocampal or cerebellar granule neuronesHemstapat, K., Smith, S. A., Monteith, G. R. and Smith, M. T. (2003). The neuroexcitatory morphine metabolite, morphine-3-glucuronide (M3G), is not neurotoxic in primary cultures of either hippocampal or cerebellar granule neurones. Pharmacology & Toxicology, 93 (4), 197-200. doi: 10.1034/j.1600-0773.2003.930408.x |
2002 Journal Article The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slices.Smith, M. T., Cabot, P. J., Ross, F. B., Robertson, A. D. and Lewis, R. J. (2002). The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slices.. Pain, 96 (1-2), 119-127. doi: 10.1016/S0304-3959(01)00436-5 |
2001 Journal Article Sex-related differences in antinociception and tolerance development following chronic intravenous infusion of morphine in the rat: modulatory role of testosterone via morphine clearanceSouth, Samantha M., Wright, Andrew W. E., Lau, Michael, Mather, Laurence E. and Smith, Maree T. (2001). Sex-related differences in antinociception and tolerance development following chronic intravenous infusion of morphine in the rat: modulatory role of testosterone via morphine clearance. Journal of Pharmacology and Experimental Therapeutics, 297 (1), 446-457. |
2001 Journal Article The role of morphine-6-glucuronide (M6G) in pain controlSmith, Maree T. and South, Samantha M. (2001). The role of morphine-6-glucuronide (M6G) in pain control. Pain Reviews, 8 (3-4), 171-191. doi: 10.1191/0968130201pr183ra |
2001 Journal Article Analgesic tolerance to opioidsSouth, S. M. and Smith, M. T. (2001). Analgesic tolerance to opioids. Pain: Clinical Updates, 9 (5), 1-4. |
2001 Journal Article Opioid analgesic prescribing and use - an audit of analgesic prescribing by general practitioners and The Multidisciplinary Pain Centre at Royal Brisbane HospitalNissen, L. M., Tett, S. E., Cramond, T., Williams, B. and Smith, M. T. (2001). Opioid analgesic prescribing and use - an audit of analgesic prescribing by general practitioners and The Multidisciplinary Pain Centre at Royal Brisbane Hospital. British Journal of Clinical Pharmacology, 52 (6), 693-698. doi: 10.1046/j.0306-5251.2001.01502.x |
2001 Journal Article Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronideWright, AWE, Mather, LE and Smith, MT (2001). Hydromorphone-3-glucuronide - A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide. Life Sciences, 69 (4), 409-420. doi: 10.1016/S0024-3205(01)01133-X |
2000 Journal Article Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in ratsRoss, Fraser B., Wallis, Steven C. and Smith, Maree T. (2000). Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats. Pain, 84 (2-3), 421-428. doi: 10.1016/S0304-3959(99)00230-4 |
2000 Journal Article Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti ratNielsen, C. K., Ross, F. B. and Smith, M. T. (2000). Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat. Journal of Pharmacology and Experimental Therapeutics, 295 (1), 91-99. |
2000 Journal Article Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolitesSmith, MT (2000). Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolites. Clinical and Experimental Pharmacology and Physiology, 27 (7), 524-528. doi: 10.1046/j.1440-1681.2000.03290.x |
2000 Journal Article Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in ratsSmith, M. T., Nielsen, C. K., Lim-Fraser, M. Y. C., Wright, A. W. E. and Lau, M. (2000). Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats. Drug Metabolism And Disposition, 28 (2), 236-244. |
1999 Journal Article Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronideHalliday, Andrew J., Bartlett, Selena E., Colditz, Paul and Smith, Maree T. (1999). Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronide. Life Sciences, 65 (2), 225-236. doi: 10.1016/S0024-3205(99)00239-8 |
1999 Journal Article Cerebrospinal fluid and plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide in patients before and after initiation of intracerebroventricular morphine for cancer pain managementSmith, M. T., Wright, A. W., Williams, B., Stuart, G. and Cramond, T. R. (1999). Cerebrospinal fluid and plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide in patients before and after initiation of intracerebroventricular morphine for cancer pain management. Anesthesia and analgesia, 88 (1), 109-116. doi: 10.1097/00000539-199901000-00021 |
1999 Journal Article Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritisKeates, HL, Cramond, T and Smith, MT (1999). Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis. Anesthesia and Analgesia, 89 (2), 409-415. doi: 10.1097/00000539-199908000-00030 |
1999 Journal Article Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritisKeates, Helen L., Cramond, Teresa and Smith, Maree T. (1999). Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis. Anesthesia and Analgesia, 89 (2), 409-415. |
1998 Journal Article The excitatory behavioral and antianalgesic pharmacology of normorphine- 3-glucuronide after intracerebroventricular administration to ratsSmith, Gregg D. and Smith, Maree T. (1998). The excitatory behavioral and antianalgesic pharmacology of normorphine- 3-glucuronide after intracerebroventricular administration to rats. Journal of Pharmacology and Experimental Therapeutics, 285 (3), 1157-1162. |
1998 Journal Article Hydromorphone-3-glucuronide: Biochemical synthesis and preliminary pharmacological evaluationWright, AWE, Nocente, ML and Smith, MT (1998). Hydromorphone-3-glucuronide: Biochemical synthesis and preliminary pharmacological evaluation. Life Sciences, 63 (5), 401-411. doi: 10.1016/S0024-3205(98)00288-4 |