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1998

Journal Article

Investigation of the antinociceptive efficacy and relative potency of extended duration injectable 3-acylmorphine-6-sulfate prodrugs in rats

Preechagoon, D, Smith, MT and Prankerd, RJ (1998). Investigation of the antinociceptive efficacy and relative potency of extended duration injectable 3-acylmorphine-6-sulfate prodrugs in rats. International Journal of Pharmaceutics, 163 (1-2), 191-201. doi: 10.1016/S0378-5173(97)00380-3

Investigation of the antinociceptive efficacy and relative potency of extended duration injectable 3-acylmorphine-6-sulfate prodrugs in rats

1998

Journal Article

The excitatory behavioral and antianalgesic pharmacology of normorphine-3-glucuronide after intracerebroventricular administration to rats

Smith, GD and Smith, MT (1998). The excitatory behavioral and antianalgesic pharmacology of normorphine-3-glucuronide after intracerebroventricular administration to rats. Journal of Pharmacology And Experimental Therapeutics, 285 (3), 1157-1162.

The excitatory behavioral and antianalgesic pharmacology of normorphine-3-glucuronide after intracerebroventricular administration to rats

1998

Journal Article

Hydromorphone-3-glucuronide: Biochemical synthesis and preliminary pharmacological evaluation

Wright, AWE, Nocente, ML and Smith, MT (1998). Hydromorphone-3-glucuronide: Biochemical synthesis and preliminary pharmacological evaluation. Life Sciences, 63 (5), 401-411. doi: 10.1016/S0024-3205(98)00288-4

Hydromorphone-3-glucuronide: Biochemical synthesis and preliminary pharmacological evaluation

1998

Journal Article

Apparent insensitivity of the hotplate latency test for detection of antinociception following intraperitoneal, intravenous or intracerebroventricular M6G administration to rats

South, SM and Smith, MT (1998). Apparent insensitivity of the hotplate latency test for detection of antinociception following intraperitoneal, intravenous or intracerebroventricular M6G administration to rats. Journal of Pharmacology And Experimental Therapeutics, 286 (3), 1326-1332.

Apparent insensitivity of the hotplate latency test for detection of antinociception following intraperitoneal, intravenous or intracerebroventricular M6G administration to rats

1998

Journal Article

Improved one-step solid-phase extraction method for morphine, morphine-3-glucuronide, and morphine-6-glucuronide from plasma and quantitation using high-performance liquid chromatography with electrochemical detection

Wright, AWE and Smith, MT (1998). Improved one-step solid-phase extraction method for morphine, morphine-3-glucuronide, and morphine-6-glucuronide from plasma and quantitation using high-performance liquid chromatography with electrochemical detection. Therapeutic Drug Monitoring, 20 (2), 215-218. doi: 10.1097/00007691-199804000-00013

Improved one-step solid-phase extraction method for morphine, morphine-3-glucuronide, and morphine-6-glucuronide from plasma and quantitation using high-performance liquid chromatography with electrochemical detection

1997

Journal Article

Biochemical synthesis, purification and preliminary pharmacological evaluation of normorphine-3-glucuronide

Smith, GD, Prankerd, RJ and Smith, MT (1997). Biochemical synthesis, purification and preliminary pharmacological evaluation of normorphine-3-glucuronide. Life Sciences, 61 (2), 95-104. doi: 10.1016/S0024-3205(97)00364-0

Biochemical synthesis, purification and preliminary pharmacological evaluation of normorphine-3-glucuronide

1997

Journal Article

Morphine has a dual concentration-dependent effect on K+-evoked substance P release from rat peripheral airways

Cabot, PJ, Cramond, T and Smith, MT (1997). Morphine has a dual concentration-dependent effect on K+-evoked substance P release from rat peripheral airways. Pulmonary Pharmacology & Therapeutics, 10 (4), 215-221. doi: 10.1006/pupt.1997.0094

Morphine has a dual concentration-dependent effect on K+-evoked substance P release from rat peripheral airways

1997

Journal Article

The intrinsic antinociceptive effects of oxycodone appear to be kappa-opioid receptor mediated

Ross, FB and Smith, MT (1997). The intrinsic antinociceptive effects of oxycodone appear to be kappa-opioid receptor mediated. Pain, 73 (2), 151-157. doi: 10.1016/S0304-3959(97)00093-6

The intrinsic antinociceptive effects of oxycodone appear to be kappa-opioid receptor mediated

1996

Journal Article

Quantitative autoradiography of peripheral opioid binding sites in rat lung

Cabot, PJ, Cramond, T and Smith, MT (1996). Quantitative autoradiography of peripheral opioid binding sites in rat lung. European Journal of Pharmacology, 310 (1), 47-53. doi: 10.1016/0014-2999(96)00363-9

Quantitative autoradiography of peripheral opioid binding sites in rat lung

1995

Journal Article

Effects of morphine-3-glucuronide and morphine on the K+-evoked release of [H-3]-glutamic acid and [C-14]-gamma-aminobutyric acid from rat brain synaptosomes

Bartlett, SE and Smith, MT (1995). Effects of morphine-3-glucuronide and morphine on the K+-evoked release of [H-3]-glutamic acid and [C-14]-gamma-aminobutyric acid from rat brain synaptosomes. Life Sciences, 58 (5), 447-454. doi: 10.1016/0024-3205(95)02310-0

Effects of morphine-3-glucuronide and morphine on the K+-evoked release of [H-3]-glutamic acid and [C-14]-gamma-aminobutyric acid from rat brain synaptosomes

1995

Journal Article

the apparent affinity of morphine-3-glucuronide at μ1-opioid receptors results from morphine contamination: demonstration using HPLC and radioligand binding

E. Bartlett, S and T. Smith, M (1995). the apparent affinity of morphine-3-glucuronide at μ1-opioid receptors results from morphine contamination: demonstration using HPLC and radioligand binding. Life Sciences, 57 (6), 609-615. doi: 10.1016/0024-3205(95)00311-S

the apparent affinity of morphine-3-glucuronide at μ1-opioid receptors results from morphine contamination: demonstration using HPLC and radioligand binding

1995

Journal Article

The Apparent Affinity of Morphine-3-Glucuronide At Mu(1)-Opioid Receptors Results From Morphine Contamination - Demonstration Using Hplc and Radioligand Binding

Bartlett, SE and Smith, MT (1995). The Apparent Affinity of Morphine-3-Glucuronide At Mu(1)-Opioid Receptors Results From Morphine Contamination - Demonstration Using Hplc and Radioligand Binding. Life Sciences, 57 (6), 609-615.

The Apparent Affinity of Morphine-3-Glucuronide At Mu(1)-Opioid Receptors Results From Morphine Contamination - Demonstration Using Hplc and Radioligand Binding

1995

Journal Article

Morphine-3-glucuronide: evidence to support its putative role in the development of tolerance to the antinociceptive effects of morphine in the rat

Smith G.D. and Smith M.T. (1995). Morphine-3-glucuronide: evidence to support its putative role in the development of tolerance to the antinociceptive effects of morphine in the rat. Pain, 62 (1), 51-60. doi: 10.1016/0304-3959(94)00228-7

Morphine-3-glucuronide: evidence to support its putative role in the development of tolerance to the antinociceptive effects of morphine in the rat

1995

Journal Article

Pharmacokinetics and pharmacodynamics of oxycodone when given intravenously and rectally to adult patients with cancer pain

Leow, KP, Cramond, T and Smith, MT (1995). Pharmacokinetics and pharmacodynamics of oxycodone when given intravenously and rectally to adult patients with cancer pain. Anesthesia and Analgesia, 80 (2), 296-302. doi: 10.1097/00000539-199502000-00016

Pharmacokinetics and pharmacodynamics of oxycodone when given intravenously and rectally to adult patients with cancer pain

1994

Journal Article

UNTITLED - COMMENTS

SMITH, M and CRAMOND, T (1994). UNTITLED - COMMENTS. Pain, 59 (1), 155-156. doi: 10.1016/0304-3959(94)90065-5

UNTITLED - COMMENTS

1994

Journal Article

Pharmacology of Morphine and Morphine-3-Glucuronide At Opioid, Excitatory Amino-Acid, Gaba and Glycine Binding-Sites

Bartlett, SE, Dodd, PR and Smith, MT (1994). Pharmacology of Morphine and Morphine-3-Glucuronide At Opioid, Excitatory Amino-Acid, Gaba and Glycine Binding-Sites. Pharmacology & Toxicology, 75 (2), 73-81. doi: 10.1111/j.1600-0773.1994.tb00327.x

Pharmacology of Morphine and Morphine-3-Glucuronide At Opioid, Excitatory Amino-Acid, Gaba and Glycine Binding-Sites

1994

Journal Article

Characterization of Nonconventional Opioid Binding-Sites in Rat and Human Lung

Cabot, PJ, Dodd, PR, Cramond, T and Smith, MT (1994). Characterization of Nonconventional Opioid Binding-Sites in Rat and Human Lung. European Journal of Pharmacology-Molecular Pharmacology Section, 268 (2), 247-255. doi: 10.1016/0922-4106(94)90195-3

Characterization of Nonconventional Opioid Binding-Sites in Rat and Human Lung

1994

Journal Article

Quantitation of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide in Plasma and Cerebrospinal-Fluid Using Solid-Phase Extraction and High-Performance Liquid-Chromatography with Electrochemical Detection

Wright, Awe, Watt, JA, Kennedy, M, Cramond, T and Smith, MT (1994). Quantitation of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide in Plasma and Cerebrospinal-Fluid Using Solid-Phase Extraction and High-Performance Liquid-Chromatography with Electrochemical Detection. Therapeutic Drug Monitoring, 16 (2), 200-208. doi: 10.1097/00007691-199404000-00016

Quantitation of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide in Plasma and Cerebrospinal-Fluid Using Solid-Phase Extraction and High-Performance Liquid-Chromatography with Electrochemical Detection

1994

Journal Article

The Antinociceptive Potencies of Oxycodone, Noroxycodone and Morphine After Intracerebroventricular Administration to Rats

Leow, KP and Smith, MT (1994). The Antinociceptive Potencies of Oxycodone, Noroxycodone and Morphine After Intracerebroventricular Administration to Rats. Life Sciences, 54 (17), 1229-1236. doi: 10.1016/0024-3205(94)00849-3

The Antinociceptive Potencies of Oxycodone, Noroxycodone and Morphine After Intracerebroventricular Administration to Rats

1994

Journal Article

The antinociceptive potencies of oxycodone, noroxycodone and morphine after intracerebroventricular administration to rats

Leow, K P and Smith, M T (1994). The antinociceptive potencies of oxycodone, noroxycodone and morphine after intracerebroventricular administration to rats. Life sciences, 54 (17), 1229-36.

The antinociceptive potencies of oxycodone, noroxycodone and morphine after intracerebroventricular administration to rats