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2010 Journal Article A randomized, controlled trial of oxycodone versus placebo in patients with postherpetic neuralgia and painful diabetic neuropathy treated with pregabalinZin, Che S., Nissen, Lisa M., O'Callaghan, James P., Duffull, Stephen B., Smith, Maree T. and Moore, Brendan J. (2010). A randomized, controlled trial of oxycodone versus placebo in patients with postherpetic neuralgia and painful diabetic neuropathy treated with pregabalin. Journal of Pain, 11 (5), 462-471. doi: 10.1016/j.jpain.2009.09.003 |
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2010 Journal Article Preliminary study of the plasma and cerebrospinal fluid concentrations of IL-6 and IL-10 in patients with chronic pain receiving intrathecal opioid infusions by chronically implanted pump for pain managementZin, Che S., Nissen, Lisa M., O'Callaghan, James P., Moore, Brendan J. and Smith, Maree T. (2010). Preliminary study of the plasma and cerebrospinal fluid concentrations of IL-6 and IL-10 in patients with chronic pain receiving intrathecal opioid infusions by chronically implanted pump for pain management. Pain Medicine, 11 (4), 550-561. doi: 10.1111/j.1526-4637.2010.00821.x |
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2009 Journal Article X-conopeptide pharmacophore development: Toward a novel class of norepinephrine transporter inhibitor (Xen2174) for painBrust, Andreas, Palant, Elka, Croker, Daniel E., Colless, Barbara, Drinkwater, Roger, Patterson, Brad, Schroeder, Christina I., Wilson, David, Nielsen, Carsten K., Smith, Maree T., Alewood, Danne, Alewood, Paul F and Lewis, Richard J. (2009). X-conopeptide pharmacophore development: Toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain. Journal of Medicinal Chemistry, 52 (22), 6991-7002. doi: 10.1021/jm9003413 |
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2009 Journal Article Innovation in drug developmentSmith, M.T. (2009). Innovation in drug development. BioSpectrum Asia CRAMS Resources Guide, 52-53. |
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2009 Journal Article Antinociception versus serum concentration relationships following acute administration of intravenous morphine in male and female Sprague-dawley rats: Differences between the tail flick and hot plate nociceptive testsSouth, Samantha M., Edwards, Stephen R. and Smith, Maree T. (2009). Antinociception versus serum concentration relationships following acute administration of intravenous morphine in male and female Sprague-dawley rats: Differences between the tail flick and hot plate nociceptive tests. Clinical and Experimental Pharmacology and Physiology, 36 (1), 20-28. doi: 10.1111/j.1440-1681.2008.05019.x |
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2009 Journal Article Comparative studies of the neuro-excitatory behavioural effects of morphine-3-glucuronide and dynorphin A (2-17) following spinal and supraspinal routes of administrationHemstapat, K., Le, L., Edwards, S. R. and Smith, M. T. (2009). Comparative studies of the neuro-excitatory behavioural effects of morphine-3-glucuronide and dynorphin A (2-17) following spinal and supraspinal routes of administration. Pharmacology, Biochemistry and Behaviour, 93 (4), 498-505. doi: 10.1016/j.pbb.2009.06.016 |
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2008 Journal Article Differences between and combinations of opiods re-visitedSmith, Maree T. (2008). Differences between and combinations of opiods re-visited. Current Opinion in Anaesthesiology, 21 (5), 596-601. doi: 10.1097/ACO.0b013e32830a4c4a |
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2008 Journal Article An update on the pharmcological management of post-herpetic neuralgia and painful diabetic neuropathyZin, Che S., Nissen, Lisa M., Smith, Maree T., O'Callaghan, James P. and Moore, Brendan J. (2008). An update on the pharmcological management of post-herpetic neuralgia and painful diabetic neuropathy. CNS Drugs, 22 (5), 417-442. doi: 10.2165/00023210-200822050-00005 |
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2008 Journal Article Sex differences in the pharmacokinetics, oxidative metabolism and oral bioactivity of oxycodone in the sprague-dawley ratChan, S., Edwards, S. R., Wyse, B. D. and Smith, M. T. (2008). Sex differences in the pharmacokinetics, oxidative metabolism and oral bioactivity of oxycodone in the sprague-dawley rat. Clinical and Experimental Pharmacology and Physiology, 35 (3), 295-302. doi: 10.1111/j.1440-1681.2007.04821.x |
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2007 Journal Article Studies with ketamine and alfentanil following Freund's complete adjuvant-induced inflammation in ratsEdwards, S. R., Mather, L. E. and Smith, M. T. (2007). Studies with ketamine and alfentanil following Freund's complete adjuvant-induced inflammation in rats. Clinical and Experimental Pharmacology and Physiology, 34 (5-6), 414-420. doi: 10.1111/j.1440-1681.2007.04581.x |
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2007 Journal Article Low-level quantitation of oxycodone and its oxidative metabolites, noroxycodone, and oxymorphone, in rat plasma by high performance liquid chromatography-electrospray ionization-tandem mass spectrometryEdwards, Stephen R. and Smith, Maree T. (2007). Low-level quantitation of oxycodone and its oxidative metabolites, noroxycodone, and oxymorphone, in rat plasma by high performance liquid chromatography-electrospray ionization-tandem mass spectrometry. Journal of Chromatography B, 848 (2), 264-270. doi: 10.1016/j.jchromb.2006.10.039 |
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2007 Journal Article Oxycodone's mechanism of action and potency differences after spinal and systemic routes of administrationSmith, Maree T., Edwards, Stephen R. and Nielsen, Carsten K. (2007). Oxycodone's mechanism of action and potency differences after spinal and systemic routes of administration. Anesthesiology, 106 (5), 1063-1064. doi: 10.1097/01.anes.0000265176.75372.ed |
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2007 Journal Article Oxycodone and morphine have distinctly different pharmacological profiles: Radioligand binding and behavioural studies in two rat models of neuropathic painNielsen, Carsten K., Ross, Fraser B., Lotfipour, Shahrdad, Saini, Kamal S., Edwards, Stephen R. and Smith, Maree T. (2007). Oxycodone and morphine have distinctly different pharmacological profiles: Radioligand binding and behavioural studies in two rat models of neuropathic pain. Pain, 132 (3), 289-300. doi: 10.1016/j.pain.2007.03.022 |
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2005 Journal Article Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic painNielsen, Carsten K., Lewis, Richard J., Alewood, Dianne, Drinkwater, Roger, Palant, Elka, Patterson, Margaret, Yaksh, Tony L, McCumber, Damon and Smith, Maree T. (2005). Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic pain. Pain, 118 (1-2), 112-124. doi: 10.1016/j.pain.2005.08.002 |
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2005 Journal Article Ventilatory responses of healthy subjects to intravenous combinations of morphine and oxycodone under imposed hypercapnic and hypoxaemic conditionsLadd, L. A., Kam, P. C., Williams, D. B., Wright, A. W. E., Smith, M. T. and Mather, L. E. (2005). Ventilatory responses of healthy subjects to intravenous combinations of morphine and oxycodone under imposed hypercapnic and hypoxaemic conditions. British Journal of Clinical Pharmacology, 59 (5), 524-535. doi: 10.1111/j.1365-2125.2005.02368.x |
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2005 Journal Article Co-administration of oxycodone and morphine and analgesic synergy re-examinedSmith, MT and de la Iglesia, FA (2005). Co-administration of oxycodone and morphine and analgesic synergy re-examined. British Journal of Clinical Pharmacology, 59 (4), 486-487. doi: 10.1111/j.1365-2125.2005.02345_1.x |
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2005 Journal Article Simultaneous determination of morphine, oxycodone, morphine-3-glucuronide, and noroxycodone concentrations in rat serum by high performance liquid chromatography-electrospray ionization-tandem mass spectrometryEdwards, S. R. and Smith, M. T. (2005). Simultaneous determination of morphine, oxycodone, morphine-3-glucuronide, and noroxycodone concentrations in rat serum by high performance liquid chromatography-electrospray ionization-tandem mass spectrometry. Journal of Chromatography B, 814 (2), 241-249. doi: 10.1016/j.jchromb.2004.10.035 |
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2005 Journal Article Comparison of the pharmacokinetics of oxycodone and noroxycodone in male dark agouti and Sprague-Dawley rats: Influence of streptozotocin-induced diabetesHuang, L., Edwards, S. R. and Smith, M. T. (2005). Comparison of the pharmacokinetics of oxycodone and noroxycodone in male dark agouti and Sprague-Dawley rats: Influence of streptozotocin-induced diabetes. Pharmaceutical Research, 22 (9), 1489-1498. doi: 10.1007/s11095-005-6154-y |
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2004 Journal Article Measurement of intracellular Ca2+ in cultured rat embryonic hippocampal neurons using a fluorescence microplate reader: Potential application to biomolecular screeningHemstapat, K, Smith, M. T. and Monteith, G. R. (2004). Measurement of intracellular Ca2+ in cultured rat embryonic hippocampal neurons using a fluorescence microplate reader: Potential application to biomolecular screening. Journal of Pharmacological and Toxicological Methods, 49 (2), 81-87. doi: 10.1016/j.vascn.2003.10.002 |
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2004 Journal Article Deletion of guanine nucleotide binding protein az subunit in mice induces a gene dose dependent tolerance to morphineLeck, KJ, Bartlett, SE, Smith, MT, Megirian, D, Holgate, J, Powell, KL, Matthaei, KI and Hendry, IA (2004). Deletion of guanine nucleotide binding protein az subunit in mice induces a gene dose dependent tolerance to morphine. Neuropharmacology, 46 (6), 836-846. doi: 10.1016/j.neuropharm.2003.11.024 |
