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2010 Journal Article Glycosaminoglycans modulate RANKL-induced osteoclastogenesisLing, Ling, Murali, Sadasivam, Stein, Gary S., Van Wijnen, Andre J. and Cool, Simon M. (2010). Glycosaminoglycans modulate RANKL-induced osteoclastogenesis. Journal of Cellular Biochemistry, 109 (6), 1222-1231. doi: 10.1002/jcb.22506 |
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2010 Journal Article Impact of vitronectin concentration and surface properties on the stable propagation of human embryonic stem cellsLib, Jian, Bardy, Jo'an, Yap, Lynn Y.W., Chen, Allen, Nurcombe, Victor, Cool, Simon M., Oh, Steve K. W. and Birch, William R. (2010). Impact of vitronectin concentration and surface properties on the stable propagation of human embryonic stem cells. Biointerphases, 5 (3), 132-142. doi: 10.1116/1.3525804 |
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2010 Journal Article The influence of fibrin based hydrogels on the chondrogenic differentiation of human bone marrow stromal cellsHo, Saey T.B., Cool, Simon M., Hui, James H. and Hutmacher, Dietmar W. (2010). The influence of fibrin based hydrogels on the chondrogenic differentiation of human bone marrow stromal cells. Biomaterials, 31 (1), 38-47. doi: 10.1016/j.biomaterials.2009.09.021 |
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2010 Journal Article FGF-2 modulates Wnt signaling in undifferentiated hESC and iPS cells through activated PI3-K/GSK3β signalingDing, Vanessa M. Y., Ling, Ling, Natarajan, Subaashini, Yap, Miranda G. S., Cool, Simon M. and Choo, Andre B. H. (2010). FGF-2 modulates Wnt signaling in undifferentiated hESC and iPS cells through activated PI3-K/GSK3β signaling. Journal of Cellular Physiology, 225 (2), 417-428. doi: 10.1002/jcp.22214 |
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2009 Journal Article Purification and characterization of heparan sulfate from human primary osteoblastsMurali, Sadasivam, Manton, Kerry J., Tjong, Vinalia, Su, Xiaodi, Haupt, Larisa M., Cool, Simon M. and Nurcombe, Victor (2009). Purification and characterization of heparan sulfate from human primary osteoblasts. Journal of Cellular Biochemistry, 108 (5), 1132-1142. doi: 10.1002/jcb.22340 |
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2009 Journal Article Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1)Pereira, Barry P., Zhou, Yefang, Gupta, Anurag, Leong, David T., Aung, Khin Zarchi, Ling, Ling, Pho, Robert W. H., Galindo, Mario, Salto-Tellez, Manuel, Stein, Gary S., Cool, Simon M., Van Wijnen, Andre J. and Nathan, Saminathan S. (2009). Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). Journal of Cellular Physiology, 221 (3), 778-788. doi: 10.1002/jcp.21921 |
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2009 Journal Article Composite electrospun scaffolds for engineering tubular bone graftsEkaputra, Andrew Krishna, Zhou, Yefang, Cool, Simon McKenzie and Hutmacher, Dietmar Werner (2009). Composite electrospun scaffolds for engineering tubular bone grafts. Tissue Engineering - Part A, 15 (12), 3779-3788. doi: 10.1089/ten.tea.2009.0186 |
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2009 Journal Article The heparan sulfate proteoglycan (HSPG) glypican-3 mediates commitment of MC3T3-E1 cells toward osteogenesisHaupt, Larisa M., Murali, Sadasivam, Foong, Kin Mun, Teplyuk, Nadiya, Leong, Fong Mei, Stein, Gary S., Van Wijnen, Andre J., Nurcombe, Victor and Cool, Simon M. (2009). The heparan sulfate proteoglycan (HSPG) glypican-3 mediates commitment of MC3T3-E1 cells toward osteogenesis. Journal of Cellular Physiology, 220 (3), 780-791. doi: 10.1002/jcp.21825 |
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2009 Journal Article De-sulfation of MG-63 cell glycosaminoglycans delays in vitro osteogenesis, up-regulates cholesterol synthesis and disrupts cell cycle and the actin cytoskeletonKumarasuriyar, A., Lee, I., Nurcombe, V. and Cool, S. M. (2009). De-sulfation of MG-63 cell glycosaminoglycans delays in vitro osteogenesis, up-regulates cholesterol synthesis and disrupts cell cycle and the actin cytoskeleton. Journal of Cellular Physiology, 219 (3), 572-583. doi: 10.1002/jcp.21700 |
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2009 Journal Article Dual loss of Rb1 and Trp53 in melanocytes perturbs melanocyte homeostasis and genetic stability in vitro but does not cause melanoma or pigmentation defects in vivoTonks, Ian D., Mould, Arne, Nurcombe, Victor, Cool, Simon M., Walker, Graeme J., Hacker, Elke, Keith, Patricia, Schroder, Wayne A., Cotterill, Andrew, Hayward, Nicholas K. and Kay, Graham F. (2009). Dual loss of Rb1 and Trp53 in melanocytes perturbs melanocyte homeostasis and genetic stability in vitro but does not cause melanoma or pigmentation defects in vivo. Pigment Cell and Melanoma Research, 22 (3), 328-330. doi: 10.1111/j.1755-148X.2009.00560.x |
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2009 Journal Article The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblastsTeplyuk, Nadiya M., Haupt, Larisa M., Ling, Ling, Dombrowski, Christian, Foong, Kin Mun, Nathan, Saminathan S., Lian, Jane B., Stein, Janet L., Stein, Gary S., Cool, Simon M. and Van Wijnen, Andre J. (2009). The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts. Journal of Cellular Biochemistry, 107 (1), 144-154. doi: 10.1002/jcb.22108 |
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2009 Journal Article The stimulation of healing within a rat calvarial defect by mPCL-TCP/collagen scaffolds loaded with rhBMP-2Sawyer, A. A., Song, S. J., Susanto, E., Chuan, P., Lam, C. X.F., Woodruff, M. A., Hutmacher, D. W. and Cool, S. M. (2009). The stimulation of healing within a rat calvarial defect by mPCL-TCP/collagen scaffolds loaded with rhBMP-2. Biomaterials, 30 (13), 2479-2488. doi: 10.1016/j.biomaterials.2008.12.055 |
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2009 Journal Article Wnt signaling controls the fate of mesenchymal stem cellsLing, Ling, Nurcombe, Victor and Cool, Simon M. (2009). Wnt signaling controls the fate of mesenchymal stem cells. Gene, 433 (1-2), 1-7. doi: 10.1016/j.gene.2008.12.008 |
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2009 Journal Article Glycosaminoglycan composition changes with MG-63 osteosarcoma osteogenesis in vitro and induces human mesenchymal stem cell aggregationKumarasuriyar, A., Murali, S., Nurcombe, V. and Cool, S. M. (2009). Glycosaminoglycan composition changes with MG-63 osteosarcoma osteogenesis in vitro and induces human mesenchymal stem cell aggregation. Journal of Cellular Physiology, 218 (3), 501-511. doi: 10.1002/jcp.21620 |
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2009 Journal Article Osteoblasts up-regulate the expression of extracellular proteases following attachment to Poly(β-hydroxybutyrate-co-β-hydroxyvalerate)Kumarasuriyar, Arjuna, Grondahl, Lisbeth, Nurcombe, Victor and Cool, Simon M. (2009). Osteoblasts up-regulate the expression of extracellular proteases following attachment to Poly(β-hydroxybutyrate-co-β-hydroxyvalerate). Gene, 428 (1-2), 53-58. doi: 10.1016/j.gene.2008.09.020 |
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2008 Journal Article Heparan sulfate mediates the proliferation and differentiation of rat mesenchymal stem cellsDombrowski, Christian, Song, Shu Jun, Chuan, Peiying, Lim, Xinhong, Susanto, Evelyn, Sawyer, Amber A., Woodruff, Maria A., Hutmacher, Dietmar W., Nurcombe, Victor and Cool, Simon M. (2008). Heparan sulfate mediates the proliferation and differentiation of rat mesenchymal stem cells. Stem Cells and Development, 18 (4), 661-670. doi: 10.1089/scd.2008.0157 |
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2008 Journal Article Combining electrospun scaffolds with electrosprayed hydrogels leads to three-dimensional cellularization of hybrid constructsEkaputra, A. K., Prestwich, G. D., Cool, S. M. and Hutmacher, D. W. (2008). Combining electrospun scaffolds with electrosprayed hydrogels leads to three-dimensional cellularization of hybrid constructs. Biomacromolecules, 9 (8), 2097-2103. doi: 10.1021/bm800565u |
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2008 Journal Article A simple and reliable electroporation method for human bone marrow mesenchymal stem cellsHelledie, T., Nurcombe, V. and Cool, S. M. (2008). A simple and reliable electroporation method for human bone marrow mesenchymal stem cells. Stem Cells Dev, 17 (4), 837-848. doi: 10.1089/scd.2007.0209 |
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2008 Journal Article Elevated expression of Runx2 as a key parameter in the etiology of osteosarcomaNathan, S. S., Pereira, B. P., Zhou, Y. F., Gupta, A., Dombrowski, C., Soong, R., Pho, R. W., Stein, G. S., Salto-Tellez, M., Cool, S. M. and van Wijnen, A. J. (2008). Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma. Mol Biol Rep, 36 (1), 153-158. doi: 10.1007/s11033-008-9378-1 |
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2008 Journal Article Stem Cell Fate Decisions: The Role of Heparan Sulfate in the Control of Autocrine and Paracrine SignalsGrunert, M., Nurcombe, V. and Cool, S. M. (2008). Stem Cell Fate Decisions: The Role of Heparan Sulfate in the Control of Autocrine and Paracrine Signals. Current Stem Cell Research and Therapy, 3 (1), 1-8. doi: 10.2174/157488808783489417 |
