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2013 Journal Article FGFR1 signaling stimulates proliferation of human mesenchymal stem cells by inhibiting the cyclin-dependent kinase inhibitors p21Waf1 and p27Kip1Dombrowski, Christian, Helledie, Torben, Ling, Ling, Grünert, Martin, Canning, Claire A., Jones, C. Michael, Hui, James H., Nurcombe, Victor, Van Wijnen, Andre J. and Cool, Simon M. (2013). FGFR1 signaling stimulates proliferation of human mesenchymal stem cells by inhibiting the cyclin-dependent kinase inhibitors p21Waf1 and p27Kip1. Stem Cells, 31 (12), 2724-2736. doi: 10.1002/stem.1514 |
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2013 Journal Article MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcomaVan Der Deen, Margaretha, Taipaleenmäki, Hanna, Zhang, Ying, Teplyuk, Nadiya M., Gupta, Anurag, Cinghu, Senthilkumar, Shogren, Kristen, Maran, Avudaiappan, Yaszemski, Michael J., Ling, Ling, Cool, Simon M., Leong, David T., Dierkes, Christian, Zustin, Jozef, Salto-Tellez, Manuel, Ito, Yoshiaki, Bae, Suk-Chul, Zielenska, Maria, Squire, Jeremy A., Lian, Jane B., Stein, Janet L., Zambetti, Gerard P., Jones, Stephen N., Galindo, Mario, Hesse, Eric, Stein, Gary S. and Van Wijnen, Andre J. (2013). MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma. Journal of Biological Chemistry, 288 (29), 21307-21319. doi: 10.1074/jbc.M112.445890 |
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2013 Journal Article Affinity-selected heparan sulfate for bone repairMurali, S., Rai, B., Dombrowski, C., Lee, J. L.J., Lim, Z. X.H., Bramono, D. S., Ling, L., Bell, T., Hinkley, S., Nathan, S. S., Hui, J. H., Wong, H. K., Nurcombe, V. and Cool, S. M. (2013). Affinity-selected heparan sulfate for bone repair. Biomaterials, 34 (22), 5594-5605. doi: 10.1016/j.biomaterials.2013.04.017 |
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2013 Journal Article Telomere length analysis of human mesenchymal stem cells by quantitative PCRSamsonraj, Rebekah M., Raghunath, Michael, Hui, James H., Ling, Ling, Nurcombe, Victor and Cool, Simon M. (2013). Telomere length analysis of human mesenchymal stem cells by quantitative PCR. Gene, 519 (2), 348-355. doi: 10.1016/j.gene.2013.01.039 |
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2013 Journal Article The influence of collagen and hyaluronan matrices on the delivery and bioactivity of bone morphogenetic protein-2 and ectopic bone formationBhakta, Gajadhar, Lim, Zophia X.H., Rai, Bina, Lin, Tingxuan, Hui, James H., Prestwich, Glenn D., Van Wijnen, Andre J., Nurcombe, Victor and Cool, Simon M. (2013). The influence of collagen and hyaluronan matrices on the delivery and bioactivity of bone morphogenetic protein-2 and ectopic bone formation. Acta Biomaterialia, 9 (11), 9098-9106. doi: 10.1016/j.actbio.2013.07.008 |
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2012 Journal Article Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2Bhakta, Gajadhar, Rai, Bina, Lim, Zophia X.H., Hui, James H., Stein, Gary S., van Wijnen, Andre J., Nurcombe, Victor, Prestwich, Glenn D. and Cool, Simon M. (2012). Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2. Biomaterials, 33 (26), 6113-6122. doi: 10.1016/j.biomaterials.2012.05.030 |
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2012 Journal Article Heparan sulfate enhances the self-renewal and therapeutic potential of mesenchymal stem cells from human adult bone marrowHelledie, Torben, Dombrowski, Christian, Rai, Bina, Lim, Zophia X.H., Hin, Ian Lee Hock, Rider, David A., Stein, Gary S., Hong, Wanjin, Van Wijnen, Andre J., Hui, James H., Nurcombe, Victor and Cool, Simon M. (2012). Heparan sulfate enhances the self-renewal and therapeutic potential of mesenchymal stem cells from human adult bone marrow. Stem Cells and Development, 21 (11), 1897-1910. doi: 10.1089/scd.2011.0367 |
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2012 Journal Article Translating human embryonic stem cells from 2-dimensional to 3-dimensional cultures in a defined medium on laminin- and vitronectin-coated surfacesHeng, Boon Chin, Li, Jian, Chen, Allen Kuan-Liang, Reuveny, Shaul, Cool, Simon M., Birch, William R. and Oh, Steve Kah-Weng (2012). Translating human embryonic stem cells from 2-dimensional to 3-dimensional cultures in a defined medium on laminin- and vitronectin-coated surfaces. Stem Cells and Development, 21 (10), 1701-1715. doi: 10.1089/scd.2011.0509 |
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2012 Journal Article Bone marrow-derived heparan sulfate potentiates the osteogenic activity of bone morphogenetic protein-2 (BMP-2)Bramono, Diah S., Murali, Sadasivam, Rai, Bina, Ling, Ling, Poh, Wei Theng, Lim, Zophia Xuehui, Stein, Gary S., Nurcombe, Victor, van Wijnen, Andre J. and Cool, Simon M. (2012). Bone marrow-derived heparan sulfate potentiates the osteogenic activity of bone morphogenetic protein-2 (BMP-2). Bone, 50 (4), 954-964. doi: 10.1016/j.bone.2011.12.013 |
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2011 Journal Article The three-dimensional vascularization of growth factor-releasing hybrid scaffold of poly (ɛ-caprolactone)/collagen fibers and hyaluronic acid hydrogelEkaputra, Andrew K., Prestwich, Glenn D., Cool, Simon M. and Hutmacher, Dietmar W. (2011). The three-dimensional vascularization of growth factor-releasing hybrid scaffold of poly (ɛ-caprolactone)/collagen fibers and hyaluronic acid hydrogel. Biomaterials, 32 (32), 8108-8117. doi: 10.1016/j.biomaterials.2011.07.022 |
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2011 Journal Article Multifunctional silica nanoparticles with potentials of imaging and gene deliveryBhakta, Gajadhar, Sharma, Rakesh Kumar, Gupta, Nikesh, Cool, Simon, Nurcombe, Victor and Maitra, Amarnath (2011). Multifunctional silica nanoparticles with potentials of imaging and gene delivery. Nanomedicine: Nanotechnology, Biology, and Medicine, 7 (4), 472-479. doi: 10.1016/j.nano.2010.12.008 |
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2011 Journal Article The effect of human bone marrow stroma-derived heparan sulfate on the Ex vivo expansion of human cord blood hematopoietic stem cellsBramono, Diah S., Rider, David A., Murali, Sadasivam, Nurcombe, Victor and Cool, Simon M. (2011). The effect of human bone marrow stroma-derived heparan sulfate on the Ex vivo expansion of human cord blood hematopoietic stem cells. Pharmaceutical Research, 28 (6), 1385-1394. doi: 10.1007/s11095-010-0352-y |
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2011 Journal Article Comparative assessment of the effects of gender-specific heparan sulfates on mesenchymal stem cellsMurali, Sadasivam, Leong, Denise F. M., Lee, Jaslyn J. L., Cool, Simon M. and Nurcombe, Victor (2011). Comparative assessment of the effects of gender-specific heparan sulfates on mesenchymal stem cells. Journal of Biological Chemistry, 286 (20), 17755-17765. doi: 10.1074/jbc.M110.148874 |
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2011 Journal Article Defining a threshold surface density of vitronectin for the stable expansion of human embryonic stem cellsYap, Lynn Y.W., Li, Jian, Phang, In Yee, Ong, Lay Ting, Ow, Jo'An Zhu-En, Goh, James C.H., Nurcombe, Victor, Hobley, Jonathan, Choo, Andre B.H., Oh, Steve K.W., Cool, Simon M. and Birch, William R. (2011). Defining a threshold surface density of vitronectin for the stable expansion of human embryonic stem cells. Tissue Engineering - Part C: Methods, 17 (2), 193-207. doi: 10.1089/ten.tec.2010.0328 |
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2011 Journal Article Heparan sulfate-based treatments for regenerative medicineRai, Bina, Nurcombe, Victor and Cool, Simon M. (2011). Heparan sulfate-based treatments for regenerative medicine. Critical Reviews in Eukaryotic Gene Expression, 21 (1), 1-12. doi: 10.1615/CritRevEukarGeneExpr.v21.i1.10 |
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2010 Journal Article Loss of CHSY1, a secreted FRINGE enzyme, causes syndromic brachydactyly in humans via increased NOTCH signalingTian, Jing, Ling, Ling, Shboul, Mohammad, Lee, Hane, O'Connor, Brian, Merriman, Barry, Nelson, Stanley F., Cool, Simon, Ababneh, Osama H., Al-Hadidy, Azmy, Masri, Amira, Hamamy, Hanan and Reversade, Bruno (2010). Loss of CHSY1, a secreted FRINGE enzyme, causes syndromic brachydactyly in humans via increased NOTCH signaling. American Journal of Human Genetics, 87 (6), 768-778. doi: 10.1016/j.ajhg.2010.11.005 |
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2010 Journal Article Differences between in vitro viability and differentiation and in vivo bone-forming efficacy of human mesenchymal stem cells cultured on PCL-TCP scaffoldsRai, Bina, Lin, Jane L., Lim, Zophia X.H., Guldberg, Robert E., Hutmacher, Dietmar W. and Cool, Simon M. (2010). Differences between in vitro viability and differentiation and in vivo bone-forming efficacy of human mesenchymal stem cells cultured on PCL-TCP scaffolds. Biomaterials, 31 (31), 7960-7970. doi: 10.1016/j.biomaterials.2010.07.001 |
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2010 Journal Article Functional coupling between the extracellular matrix and nuclear lamina by wnt signaling in progeriaHernandez, Lidia, Roux, Kyle J., Wong, Esther Sook Miin, Mounkes, Leslie C., Mutalif, Rafidah, Navasankari, Raju, Rai, Bina, Cool, Simon, Jeong, Jae-Wook, Wang, Honghe, Lee, Hyun-Shik, Kozlov, Serguei, Grunert, Martin, Keeble, Thomas, Jones, C. Michael, Meta, Margarita D., Young, Stephen G., Daar, Ira O., Burke, Brian, Perantoni, Alan O. and Stewart, Colin L. (2010). Functional coupling between the extracellular matrix and nuclear lamina by wnt signaling in progeria. Developmental Cell, 19 (3), 413-425. doi: 10.1016/j.devcel.2010.08.013 |
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2010 Journal Article Glycosaminoglycans modulate RANKL-induced osteoclastogenesisLing, Ling, Murali, Sadasivam, Stein, Gary S., Van Wijnen, Andre J. and Cool, Simon M. (2010). Glycosaminoglycans modulate RANKL-induced osteoclastogenesis. Journal of Cellular Biochemistry, 109 (6), 1222-1231. doi: 10.1002/jcb.22506 |
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2010 Journal Article Impact of vitronectin concentration and surface properties on the stable propagation of human embryonic stem cellsLib, Jian, Bardy, Jo'an, Yap, Lynn Y.W., Chen, Allen, Nurcombe, Victor, Cool, Simon M., Oh, Steve K. W. and Birch, William R. (2010). Impact of vitronectin concentration and surface properties on the stable propagation of human embryonic stem cells. Biointerphases, 5 (3), 132-142. doi: 10.1116/1.3525804 |
