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2023 Journal Article Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitriteGutierrez, Bryan, Aggarwal, Tushar, Erguven, Huseyin, Stone, M. Rhia L., Guo, Changjiang, Bellomo, Alyssa, Abramova, Elena, Stevenson, Emily R., Laskin, Debra L., Gow, Andrew J. and Izgu, Enver Cagri (2023). Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite. iScience, 26 (12) 108567, 1-23. doi: 10.1016/j.isci.2023.108567 |
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2023 Journal Article Synthesis of vancomycin fluorescent probes that retain antimicrobial activity, identify Gram-positive bacteria, and detect Gram-negative outer membrane damageZhang, Bing, Phetsang, Wanida, Stone, M. Rhia L., Kc, Sanjaya, Butler, Mark S., Cooper, Matthew A., Elliott, Alysha G., Łapińska, Urszula, Voliotis, Margaritis, Tsaneva-Atanasova, Krasimira, Pagliara, Stefano and Blaskovich, Mark A. T. (2023). Synthesis of vancomycin fluorescent probes that retain antimicrobial activity, identify Gram-positive bacteria, and detect Gram-negative outer membrane damage. Communications Biology, 6 (1) 409, 1-16. doi: 10.1038/s42003-023-04745-x |
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2023 Journal Article Bioorthogonal functionalization of material surfaces with bioactive moleculesHast, Kern, Stone, M. Rhia L., Jia, Zhaojun, Baci, Melih, Aggarwal, Tushar and Izgu, Enver Cagri (2023). Bioorthogonal functionalization of material surfaces with bioactive molecules. ACS Applied Materials and Interfaces, 15 (4), 4996-5009. doi: 10.1021/acsami.2c20942 |
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2022 Journal Article Fast bacterial growth reduces antibiotic accumulation and efficacyŁapińska, Urszula, Voliotis, Margaritis, Lee, Ka Kiu, Campey, Adrian, Stone, Rhia M. L., Tuck, Brandon, Phetsang, Wanida, Zhang, Bing, Tsaneva-Atanasova, Krasimira, Blaskovich, Mark A. T. and Pagliara, Stefano (2022). Fast bacterial growth reduces antibiotic accumulation and efficacy. eLife, 11 e74062, 1-33. doi: 10.7554/ELIFE.74062 |
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2021 Journal Article CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophageConners, Rebecca, McLaren, Mathew, Łapińska, Urszula, Sanders, Kelly, Stone, M. Rhia L., Blaskovich, Mark A. T., Pagliara, Stefano, Daum, Bertram, Rakonjac, Jasna and Gold, Vicki A. M. (2021). CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage. Nature Communications, 12 (1) 6316, 6316. doi: 10.1038/s41467-021-26610-3 |
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2021 Journal Article Serum complement activation by C4BP-IgM fusion protein can restore susceptibility to antibiotics in Neisseria gonorrhoeaeBettoni, Serena, Maziarz, Karolina, Stone, M. Rhia L., Blaskovich, Mark A. T., Potempa, Jan, Bazzo, Maria Luiza, Unemo, Magnus, Ram, Sanjay and Blom, Anna M. (2021). Serum complement activation by C4BP-IgM fusion protein can restore susceptibility to antibiotics in Neisseria gonorrhoeae. Frontiers in Immunology, 12 726801, 1-15. doi: 10.3389/fimmu.2021.726801 |
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2021 Journal Article Route efficiency assessment and review of the synthesis of β-nucleosides: Via N -glycosylation of nucleobasesKaspar, Felix, Stone, M. Rhia L., Neubauer, Peter and Kurreck, Anke (2021). Route efficiency assessment and review of the synthesis of β-nucleosides: Via N -glycosylation of nucleobases. Green Chemistry, 23 (1), 37-50. doi: 10.1039/d0gc02665d |
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2020 Journal Article Two for the price of one: heterobivalent ligand design targeting two binding sites on voltage-gated sodium channels slows ligand dissociation and enhances otencyPeschel, Alicia, Cardoso, Fernanda C., Walker, Andrew A., Durek, Thomas, Stone, M Rhia L., Braga Emidio, Nayara, Dawson, Philip E., Muttenthaler, Markus and King, Glenn F. (2020). Two for the price of one: heterobivalent ligand design targeting two binding sites on voltage-gated sodium channels slows ligand dissociation and enhances otency. Journal of Medicinal Chemistry, 63 (21), 12773-12785. doi: 10.1021/acs.jmedchem.0c01107 |
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2020 Journal Article Visualization of bacterial resistance using fluorescent antibiotic probesStone, M. Rhia L., Phetsang, Wanida, Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Visualization of bacterial resistance using fluorescent antibiotic probes. Journal of Visualized Experiments, 2020 (157) e60743. doi: 10.3791/60743 |
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2020 Journal Article Fluorescent macrolide probes – synthesis and use in evaluation of bacterial resistanceStone, M. Rhia L., Łapińska, Urszula, Pagliara, Stefano, Masi, Muriel, Blanchfield, Joanne T., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Fluorescent macrolide probes – synthesis and use in evaluation of bacterial resistance. RSC Chemical Biology, 1 (5), 395-404. doi: 10.1039/d0cb00118j |
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2019 Journal Article Non-antibiotic small-molecule regulation of DHFR-based destabilizing domains in vivoPeng, Hui, Chau, Viet Q., Phetsang, Wanida, Sebastian, Rebecca M., Stone, M. Rhia L., Datta, Shyamtanu, Renwick, Marian, Tamer, Yusuf T., Toprak, Erdal, Koh, Andrew Y., Blaskovich, Mark A.T. and Hulleman, John D. (2019). Non-antibiotic small-molecule regulation of DHFR-based destabilizing domains in vivo. Molecular Therapy - Methods and Clinical Development, 15, 27-39. doi: 10.1016/j.omtm.2019.08.002 |
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2019 Journal Article Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and effluxStone, M. Rhia L., Masi, Muriel, Phetsang, Wanida, Pagès, Jean-Marie, Cooper, Matthew A. and Blaskovich, Mark A. T. (2019). Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux. MedChemComm, 10 (6), 901-906. doi: 10.1039/c9md00124g |
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2018 Journal Article Fluorescent Antibiotics: New Research Tools to Fight Antibiotic ResistanceStone, M Rhia L., Butler, Mark S., Phetsang, Wanida, Cooper, Matthew A. and Blaskovich, Mark A. T. (2018). Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance. Trends in Biotechnology, 36 (5), 523-536. doi: 10.1016/j.tibtech.2018.01.004 |
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2015 Journal Article ChemInform abstract: divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydratesMoore, Peter W., Schuster, Julia K., Hewitt, Russell J., Stone, M. Rhia L., Teesdale-Spittle, Paul H. and Harvey, Joanne E. (2015). ChemInform abstract: divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates. ChemInform, 46 (8), 1-1. doi: 10.1002/chin.201508276 |
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2014 Journal Article Divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydratesMoore, Peter W., Schuster, Julia K., Hewitt, Russell J., Stone, M. Rhia L., Teesdale-Spittle, Paul H. and Harvey, Joanne E. (2014). Divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates. Tetrahedron, 70 (39), 7032-7043. doi: 10.1016/j.tet.2014.06.069 |
