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2023

Journal Article

Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite

Gutierrez, Bryan, Aggarwal, Tushar, Erguven, Huseyin, Stone, M. Rhia L., Guo, Changjiang, Bellomo, Alyssa, Abramova, Elena, Stevenson, Emily R., Laskin, Debra L., Gow, Andrew J. and Izgu, Enver Cagri (2023). Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite. iScience, 26 (12) 108567, 1-23. doi: 10.1016/j.isci.2023.108567

Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite

2023

Journal Article

Synthesis of vancomycin fluorescent probes that retain antimicrobial activity, identify Gram-positive bacteria, and detect Gram-negative outer membrane damage

Zhang, Bing, Phetsang, Wanida, Stone, M. Rhia L., Kc, Sanjaya, Butler, Mark S., Cooper, Matthew A., Elliott, Alysha G., Łapińska, Urszula, Voliotis, Margaritis, Tsaneva-Atanasova, Krasimira, Pagliara, Stefano and Blaskovich, Mark A. T. (2023). Synthesis of vancomycin fluorescent probes that retain antimicrobial activity, identify Gram-positive bacteria, and detect Gram-negative outer membrane damage. Communications Biology, 6 (1) 409, 1-16. doi: 10.1038/s42003-023-04745-x

Synthesis of vancomycin fluorescent probes that retain antimicrobial activity, identify Gram-positive bacteria, and detect Gram-negative outer membrane damage

2023

Journal Article

Bioorthogonal functionalization of material surfaces with bioactive molecules

Hast, Kern, Stone, M. Rhia L., Jia, Zhaojun, Baci, Melih, Aggarwal, Tushar and Izgu, Enver Cagri (2023). Bioorthogonal functionalization of material surfaces with bioactive molecules. ACS Applied Materials and Interfaces, 15 (4), 4996-5009. doi: 10.1021/acsami.2c20942

Bioorthogonal functionalization of material surfaces with bioactive molecules

2022

Journal Article

Fast bacterial growth reduces antibiotic accumulation and efficacy

Łapińska, Urszula, Voliotis, Margaritis, Lee, Ka Kiu, Campey, Adrian, Stone, Rhia M. L., Tuck, Brandon, Phetsang, Wanida, Zhang, Bing, Tsaneva-Atanasova, Krasimira, Blaskovich, Mark A. T. and Pagliara, Stefano (2022). Fast bacterial growth reduces antibiotic accumulation and efficacy. eLife, 11 e74062, 1-33. doi: 10.7554/ELIFE.74062

Fast bacterial growth reduces antibiotic accumulation and efficacy

2021

Journal Article

CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

Conners, Rebecca, McLaren, Mathew, Łapińska, Urszula, Sanders, Kelly, Stone, M. Rhia L., Blaskovich, Mark A. T., Pagliara, Stefano, Daum, Bertram, Rakonjac, Jasna and Gold, Vicki A. M. (2021). CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage. Nature Communications, 12 (1) 6316, 6316. doi: 10.1038/s41467-021-26610-3

CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

2021

Journal Article

Serum complement activation by C4BP-IgM fusion protein can restore susceptibility to antibiotics in Neisseria gonorrhoeae

Bettoni, Serena, Maziarz, Karolina, Stone, M. Rhia L., Blaskovich, Mark A. T., Potempa, Jan, Bazzo, Maria Luiza, Unemo, Magnus, Ram, Sanjay and Blom, Anna M. (2021). Serum complement activation by C4BP-IgM fusion protein can restore susceptibility to antibiotics in Neisseria gonorrhoeae. Frontiers in Immunology, 12 726801, 1-15. doi: 10.3389/fimmu.2021.726801

Serum complement activation by C4BP-IgM fusion protein can restore susceptibility to antibiotics in Neisseria gonorrhoeae

2021

Journal Article

Route efficiency assessment and review of the synthesis of β-nucleosides: Via N -glycosylation of nucleobases

Kaspar, Felix, Stone, M. Rhia L., Neubauer, Peter and Kurreck, Anke (2021). Route efficiency assessment and review of the synthesis of β-nucleosides: Via N -glycosylation of nucleobases. Green Chemistry, 23 (1), 37-50. doi: 10.1039/d0gc02665d

Route efficiency assessment and review of the synthesis of β-nucleosides: Via N -glycosylation of nucleobases

2020

Journal Article

Two for the price of one: heterobivalent ligand design targeting two binding sites on voltage-gated sodium channels slows ligand dissociation and enhances otency

Peschel, Alicia, Cardoso, Fernanda C., Walker, Andrew A., Durek, Thomas, Stone, M Rhia L., Braga Emidio, Nayara, Dawson, Philip E., Muttenthaler, Markus and King, Glenn F. (2020). Two for the price of one: heterobivalent ligand design targeting two binding sites on voltage-gated sodium channels slows ligand dissociation and enhances otency. Journal of Medicinal Chemistry, 63 (21), 12773-12785. doi: 10.1021/acs.jmedchem.0c01107

Two for the price of one: heterobivalent ligand design targeting two binding sites on voltage-gated sodium channels slows ligand dissociation and enhances otency

2020

Journal Article

Visualization of bacterial resistance using fluorescent antibiotic probes

Stone, M. Rhia L., Phetsang, Wanida, Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Visualization of bacterial resistance using fluorescent antibiotic probes. Journal of Visualized Experiments, 2020 (157) e60743. doi: 10.3791/60743

Visualization of bacterial resistance using fluorescent antibiotic probes

2020

Journal Article

Fluorescent macrolide probes – synthesis and use in evaluation of bacterial resistance

Stone, M. Rhia L., Łapińska, Urszula, Pagliara, Stefano, Masi, Muriel, Blanchfield, Joanne T., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Fluorescent macrolide probes – synthesis and use in evaluation of bacterial resistance. RSC Chemical Biology, 1 (5), 395-404. doi: 10.1039/d0cb00118j

Fluorescent macrolide probes – synthesis and use in evaluation of bacterial resistance

2019

Journal Article

Non-antibiotic small-molecule regulation of DHFR-based destabilizing domains in vivo

Peng, Hui, Chau, Viet Q., Phetsang, Wanida, Sebastian, Rebecca M., Stone, M. Rhia L., Datta, Shyamtanu, Renwick, Marian, Tamer, Yusuf T., Toprak, Erdal, Koh, Andrew Y., Blaskovich, Mark A.T. and Hulleman, John D. (2019). Non-antibiotic small-molecule regulation of DHFR-based destabilizing domains in vivo. Molecular Therapy - Methods and Clinical Development, 15, 27-39. doi: 10.1016/j.omtm.2019.08.002

Non-antibiotic small-molecule regulation of DHFR-based destabilizing domains in vivo

2019

Journal Article

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

Stone, M. Rhia L., Masi, Muriel, Phetsang, Wanida, Pagès, Jean-Marie, Cooper, Matthew A. and Blaskovich, Mark A. T. (2019). Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux. MedChemComm, 10 (6), 901-906. doi: 10.1039/c9md00124g

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

2018

Journal Article

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance

Stone, M Rhia L., Butler, Mark S., Phetsang, Wanida, Cooper, Matthew A. and Blaskovich, Mark A. T. (2018). Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance. Trends in Biotechnology, 36 (5), 523-536. doi: 10.1016/j.tibtech.2018.01.004

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance

2015

Journal Article

ChemInform abstract: divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates

Moore, Peter W., Schuster, Julia K., Hewitt, Russell J., Stone, M. Rhia L., Teesdale-Spittle, Paul H. and Harvey, Joanne E. (2015). ChemInform abstract: divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates. ChemInform, 46 (8), 1-1. doi: 10.1002/chin.201508276

ChemInform abstract: divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates

2014

Journal Article

Divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates

Moore, Peter W., Schuster, Julia K., Hewitt, Russell J., Stone, M. Rhia L., Teesdale-Spittle, Paul H. and Harvey, Joanne E. (2014). Divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates. Tetrahedron, 70 (39), 7032-7043. doi: 10.1016/j.tet.2014.06.069

Divergent synthesis of 2-C-branched pyranosides and oxepines from 1,2-gem-dibromocyclopropyl carbohydrates