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2015 Journal Article SEC-uring membrane fusion: a sneak peek at SNARE-complex assembly driven by Sec1-Munc18 proteinsCollins, Brett M. and Martin, Jennifer Louise (2015). SEC-uring membrane fusion: a sneak peek at SNARE-complex assembly driven by Sec1-Munc18 proteins. Nature Structural and Molecular Biology, 22 (10), 756-758. doi: 10.1038/nsmb.3094 |
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2015 Journal Article Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbADuprez, Wilko, Bachu, Prabhakar, Stoermer, Martin J, Tay, Stephanie, McMahon, Roisin M, Fairlie, David P and Martin, Jennifer L (2015). Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA. Plos One, 10 (7) e0133805, e0133805. doi: 10.1371/journal.pone.0133805 |
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2015 Journal Article Small molecule inhibitors of disulfide bond formation by the bacterial DsbA-DsbB dual enzyme systemHalili, Maria A., Bachu, Prabhakar, Lindahl, Fredrik, Bechara, Cherine, Mohanty, Biswaranjan, Reid, Robert C., Scanlon, Martin, Robinson, Carol V., Fairlie, David P. and Martin, Jennifer L. (2015). Small molecule inhibitors of disulfide bond formation by the bacterial DsbA-DsbB dual enzyme system. ACS Chemical Biology, 10 (4), 957-964. doi: 10.1021/cb500988r |
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2015 Journal Article Sent packing: Protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibilityMcMahon, Roisin M., Coincon, Mathieu, Tay, Stephanie, Heras, Begona, Morton, Craig J., Scanlon, Martin J. and Martin, Jennifer L. (2015). Sent packing: Protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility. Acta Crystallographica Section D: Biological Crystallography, 71 (Pt 12), 2386-2395. doi: 10.1107/S1399004715018519 |
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2014 Journal Article Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbAAdams, Luke A., Sharma, Pooja, Mohanty, Biswaranjan, Ilyichova, Olga V., Mulcair, Mark D., Williams, Martin L., Gleeson, Ellen C., Totsika, Makrina, Doak, Bradley C., Caria, Sofia, Rimmer, Kieran, Horne, James, Shouldice, Stephen R., Vazirani, Mansha, Headey, Stephen J., Vazirani, Mansha, Headey, Stephen J., Plumb, Brent R., Martin, Jennifer L., Heras, Begona, Simpson, Jamie S. and Scanlon, Martin J. (2014). Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angewandte Chemie, 54 (7), 2179-2184. doi: 10.1002/ange.201410341 |
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2014 Journal Article Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulenceDuprez, Wilko, Premkumar, Lakshmanane, Halili, Maria A., Lindahl, Fredrik, Reid, Robert C., Fairlie, David P. and Martin, Jennifer L. (2014). Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulence. Journal of Medicinal Chemistry, 58 (2), 577-587. doi: 10.1021/jm500955s |
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2014 Journal Article SNARE-ing the structures of Sec1/Munc18 proteinsArchbold, Julia K., Whitten, Andrew E., Hu, Shu-Hong, Collins, Brett M. and Martin, Jennifer L. (2014). SNARE-ing the structures of Sec1/Munc18 proteins. Current Opinion in Structural Biology, 29, 44-51. doi: 10.1016/j.sbi.2014.09.003 |
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2014 Journal Article Ten Simple Rules to Achieve Conference Speaker Gender BalanceMartin, Jennifer L. (2014). Ten Simple Rules to Achieve Conference Speaker Gender Balance. PLoS Computational Biology, 10 (11), e1003903-e1003903. doi: 10.1371/journal.pcbi.1003903 |
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2014 Journal Article Reconciling the regulatory role of Munc18 proteins in SNARE-complex assemblyRehman, Asma, Archbold, Julia, Hu, Shu-Hong, Norwood, Suzanne, Collins, Brett and Martin, Jennifer L. (2014). Reconciling the regulatory role of Munc18 proteins in SNARE-complex assembly. IUCrJ, 1 (6), 505-513. doi: 10.1107/S2052252514020727 |
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2014 Journal Article Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to EF-Tu reveals a novel protein interaction sitePremkumar, Lakshmanane, Kurth, Fabian, Duprez, Wilko, Grøftehauge, Morten K., King, Gordon J., Halili, Maria A., Heras, Begoña and Martin, Jennifer L. (2014). Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to EF-Tu reveals a novel protein interaction site. Journal of Biological Chemistry, 289 (29), 19869-19880. doi: 10.1074/jbc.M114.571737 |
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2014 Journal Article Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand.Kurth, Fabian, Duprez, Wilko, Premkumar, Lakshmanane, Schembri, Mark A., Fairlie, David P. and Martin, Jennifer L. (2014). Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand.. Journal of Biological Chemistry, 289 (28), 19810-19822. doi: 10.1074/jbc.M114.552380 |
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2014 Journal Article Towards selective lysophospholipid GPCR modulatorsArchbold, Julia K., Martin, Jennifer L. and Sweet, Matthew J. (2014). Towards selective lysophospholipid GPCR modulators. Trends in Pharmacological Sciences, 35 (5), 219-226. doi: 10.1016/j.tips.2014.03.004 |
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2014 Journal Article Proteins to plastics: chemistry as a dynamic disciplineMartin, Jennifer Louise, Holmes, Andrew and Buntine, Mark (2014, 02 25). Proteins to plastics: chemistry as a dynamic discipline |
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2014 Journal Article Targeting virulence not viability in the search for future antibacterialsHeras, Begona, Scanlon, Martin J. and Martin, Jennifer L. (2014). Targeting virulence not viability in the search for future antibacterials. British Journal of Clinical Pharmacology, 79 (2), 208-215. doi: 10.1111/bcp.12356 |
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2014 Journal Article Four structural subclasses of the antivirulence drug target disulfide oxidoreductase DsbA provide a platform for design of subclass-specific inhibitorsMcMahon, Róisín M., Premkumar, Lakshmanane and Martin, Jennifer L. (2014). Four structural subclasses of the antivirulence drug target disulfide oxidoreductase DsbA provide a platform for design of subclass-specific inhibitors. Biochimica et Biophysica Acta: Proteins and Proteomics, In Press, Uncorrected Proof (8), 1-11. doi: 10.1016/j.bbapap.2014.01.013 |
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2013 Journal Article Milligram quantities of homogeneous recombinant full-length mouse Munc18c from Escherichia coli culturesRehman, Asma, Jarrott, Russell J., Whitten, Andrew E., King, Gordon J., Hu, Shu-Hong, Christie, Michelle P., Collins, Brett M. and Martin, Jennifer L. (2013). Milligram quantities of homogeneous recombinant full-length mouse Munc18c from Escherichia coli cultures. PloS One, 8 (12) e83499, e83499.1-e83499.12. doi: 10.1371/journal.pone.0083499 |
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2013 Journal Article Structural insights into the role of the cyclic backbone in a squash trypsin inhibitorDaly, Norelle L., Thorstholm, Louise, Greenwood, Kathryn P., King, Gordon J., Rosengren, K. Johan, Heras, Begona, Martin, Jennifer L. and Craik, David J. (2013). Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor. Journal of Biological Chemistry, 288 (50), 36141-36148. doi: 10.1074/jbc.M113.528240 |
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2013 Journal Article The multidrug resistance IncA/C transferable plasmid encodes a novel domain swapped dimeric protein disulfide isomerasePremkumar, Lakshmanane, Kurth, Fabian, Neyer, Simon, Schembri, Mark A. and Martin, Jennifer L. (2013). The multidrug resistance IncA/C transferable plasmid encodes a novel domain swapped dimeric protein disulfide isomerase. Journal of Biological Chemistry, Papers in Press (5), 1-24. doi: 10.1074/jbc.M113.516898 |
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2013 Journal Article The alpha-proteobacteria Wolbachia pipientis protein disulfide machinery has a regulatory mechanism absent in gamma-proteobacteriaWalden, Patricia, Halili, Maria, Julia Archbold, Fredrik Lindahl, Fairlie, David P., Inaba, Kenji and Martin, Jennifer L. (2013). The alpha-proteobacteria Wolbachia pipientis protein disulfide machinery has a regulatory mechanism absent in gamma-proteobacteria. PloS One, 8 (11) e81440, e81440.1-e81440.9. doi: 10.1371/journal.pone.0081440 |
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2013 Journal Article Comparative sequence, structure and redox analyses of Klebsiella pneumoniae DsbA show that anti-virulence target DsbA enzymes fall into distinct classesKurth, Fabian, Rimmer, Kieran, Premkumar, Lakshmanane, Mohanty, Biswaranjan, Duprez, Wilko, Halili, Maria A., Shouldice, Stephen R., Heras, Begoña, Fairlie, David P., Scanlon, Martin J. and Martin, Jennifer L. (2013). Comparative sequence, structure and redox analyses of Klebsiella pneumoniae DsbA show that anti-virulence target DsbA enzymes fall into distinct classes. PloS One, 8 (11) e80210, e80210.1-e80210.15. doi: 10.1371/journal.pone.0080210 |
