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2020

Journal Article

Synthetic tigliane intermediates engage thiols to induce potent cell line selective anti‐cancer activity

Chow, Sharon, Krainz, Tanja, Bettencourt, Christian J., Broit, Natasa, Ferguson, Blake, Zhu, Mingzhao, Hull, Kenneth G., Pierens, Gregory K., Bernhardt, Paul V., Parsons, Peter G., Romo, Daniel, Boyle, Glen M. and Williams, Craig M. (2020). Synthetic tigliane intermediates engage thiols to induce potent cell line selective anti‐cancer activity. Chemistry: A European Journal, 26 (59) chem.202003221, 13372-13377. doi: 10.1002/chem.202003221

Synthetic tigliane intermediates engage thiols to induce potent cell line selective anti‐cancer activity

2020

Journal Article

The fundamental importance of basic science: examples of high-impact discoveries from an international chemistry network

Lopes, Luiz G.F., Sadler, Peter J., Bernardes-Génisson, Vânia, Moura, José J.G., Chauvin, Remi, Bernhardt, Paul V. and Sousa, Eduardo H.S. (2020). The fundamental importance of basic science: examples of high-impact discoveries from an international chemistry network. Quimica Nova, 43 (8), 1-14. doi: 10.21577/0100-4042.20170584

The fundamental importance of basic science: examples of high-impact discoveries from an international chemistry network

2020

Journal Article

Cytochrome c reductase is a key enzyme involved in the extracellular electron transfer pathway towards transition metal complexes in Pseudomonas putida

Lai, Bin, Bernhardt, Paul V. and Krömer, Jens O. (2020). Cytochrome c reductase is a key enzyme involved in the extracellular electron transfer pathway towards transition metal complexes in Pseudomonas putida. ChemSusChem, 13 (19) cssc.202001645, 5308-5317. doi: 10.1002/cssc.202001645

Cytochrome c reductase is a key enzyme involved in the extracellular electron transfer pathway towards transition metal complexes in Pseudomonas putida

2020

Journal Article

Kalparinol, a Salvialane (Isodaucane) sesquiterpenoid derived from native Australian dysphania species that suggests a putative biogenetic link to zerumbone

Tan, Yuen Ping, Savchenko, Andrei I., Agnew-Francis, Kylie A., Boyle, Glen M., Bernhardt, Paul V., Fraser, James A. and Williams, Craig M. (2020). Kalparinol, a Salvialane (Isodaucane) sesquiterpenoid derived from native Australian dysphania species that suggests a putative biogenetic link to zerumbone. Journal of Natural Products, 83 (5) acs.jnatprod.9b01039, 1473-1479. doi: 10.1021/acs.jnatprod.9b01039

Kalparinol, a Salvialane (Isodaucane) sesquiterpenoid derived from native Australian dysphania species that suggests a putative biogenetic link to zerumbone

2020

Journal Article

Dysidealactams and dysidealactones: sesquiterpene glycinyl-lactams, imides, and lactones from a Dysidea sp. marine sponge collected in Southern Australia

Khushi, Shamsunnahar, Salim, Angela A., Elbanna, Ahmed H., Nahar, Laizuman, Bernhardt, Paul V. and Capon, Robert J. (2020). Dysidealactams and dysidealactones: sesquiterpene glycinyl-lactams, imides, and lactones from a Dysidea sp. marine sponge collected in Southern Australia. Journal of Natural Products, 83 (5) acs.jnatprod.0c00041, 1577-1584. doi: 10.1021/acs.jnatprod.0c00041

Dysidealactams and dysidealactones: sesquiterpene glycinyl-lactams, imides, and lactones from a Dysidea sp. marine sponge collected in Southern Australia

2020

Journal Article

Biophysical techniques for distinguishing ligand binding modes in cytochrome P450 monooxygenases

Podgorski, Matthew N., Harbort, Joshua S., Coleman, Tom, Stok, Jeanette E., Yorke, Jake A., Wong, Luet-Lok, Bruning, John B., Bernhardt, Paul V., De Voss, James J., Harmer, Jeffrey R. and Bell, Stephen G. (2020). Biophysical techniques for distinguishing ligand binding modes in cytochrome P450 monooxygenases. Biochemistry, 59 (9) acs.biochem.0c00027, 1038-1050. doi: 10.1021/acs.biochem.0c00027

Biophysical techniques for distinguishing ligand binding modes in cytochrome P450 monooxygenases

2020

Journal Article

Humulene diepoxides from the Australian arid zone herb Dysphania: assignment of aged hops constituents

Tan, Yuen Ping, Agnew‐Francis, Kylie A., Hofmann, Julian, Savchenko, Andrei I., Lafontaine, Scott R., Boyle, Glen M., Bernhardt, Paul V., Fraser, James A., Shellhammer, Thomas H. and Williams, Craig M. (2020). Humulene diepoxides from the Australian arid zone herb Dysphania: assignment of aged hops constituents. Chemistry: A European Journal, 26 (7) chem.201904420, 1653-1660. doi: 10.1002/chem.201904420

Humulene diepoxides from the Australian arid zone herb Dysphania: assignment of aged hops constituents

2020

Journal Article

Chrysosporazines F–M: P-glycoprotein inhibitory phenylpropanoid piperazines from an Australian marine fish derived fungus, Chrysosporium sp. CMB-F294

Mohamed, Osama G., Salim, Angela A., Khalil, Zeinab G., Elbanna, Ahmed H., Bernhardt, Paul V. and Capon, Robert J. (2020). Chrysosporazines F–M: P-glycoprotein inhibitory phenylpropanoid piperazines from an Australian marine fish derived fungus, Chrysosporium sp. CMB-F294. Journal of Natural Products, 83 (2) acs.jnatprod.9b01181, 497-504. doi: 10.1021/acs.jnatprod.9b01181

Chrysosporazines F–M: P-glycoprotein inhibitory phenylpropanoid piperazines from an Australian marine fish derived fungus, Chrysosporium sp. CMB-F294

2020

Journal Article

The oxidation-reduction and electrocatalytic properties of CO dehydrogenase from Oligotropha carboxidovorans

Kalimuthu, Palraj, Petitgenet, Mélanie, Niks, Dimitri, Dingwall, Stephanie, Harmer, Jeffrey R., Hille, Russ and Bernhardt, Paul V. (2020). The oxidation-reduction and electrocatalytic properties of CO dehydrogenase from Oligotropha carboxidovorans. Biochimica et Biophysica Acta - Bioenergetics, 1861 (1) 148118, 148118. doi: 10.1016/j.bbabio.2019.148118

The oxidation-reduction and electrocatalytic properties of CO dehydrogenase from Oligotropha carboxidovorans

2020

Journal Article

Copper complexes of benzoylacetone bis-thiosemicarbazones: metal and ligand based redox reactivity*

Bilyj, Jessica K., Harmer, Jeffrey R. and Bernhardt, Paul V. (2020). Copper complexes of benzoylacetone bis-thiosemicarbazones: metal and ligand based redox reactivity*. Australian Journal of Chemistry, 74 (1), 34-47. doi: 10.1071/ch20210

Copper complexes of benzoylacetone bis-thiosemicarbazones: metal and ligand based redox reactivity*

2019

Journal Article

A novel long‐range n to π* interaction secures the smallest known α‐helix in water

Hoang, Huy N., Wu, Chongyang, Hill, Timothy A., Dantas de Araujo, Aline, Bernhardt, Paul V., Liu, Ligong and Fairlie, David P. (2019). A novel long‐range n to π* interaction secures the smallest known α‐helix in water. Angewandte Chemie, 131 (52), 19049-19053. doi: 10.1002/ange.201911277

A novel long‐range n to π* interaction secures the smallest known α‐helix in water

2019

Journal Article

A spectroelectrochemical investigation of the heme-based sensor DevS from Mycobacterium tuberculosis: a redox versus oxygen sensor

Barreto, Giamwemberg A., Carepo, Marta S. P., Gondim, Ana C. S., Guimaraes, Wellinson G., Lopes, Luiz G. F., Bernhardt, Paul, Paulo, Tercio F., Sousa, Eduardo H. S. and Diogenes, Izaura C. N. (2019). A spectroelectrochemical investigation of the heme-based sensor DevS from Mycobacterium tuberculosis: a redox versus oxygen sensor. Febs Journal, 286 (21) febs.14974, 4278-4293. doi: 10.1111/febs.14974

A spectroelectrochemical investigation of the heme-based sensor DevS from Mycobacterium tuberculosis: a redox versus oxygen sensor

2019

Journal Article

En route to D-ring inverted phorbol esters

Chow, Sharon, Krainz, Tanja, Bernhardt, Paul V. and Williams, Craig M. (2019). En route to D-ring inverted phorbol esters. Organic Letters, 21 (21) acs.orglett.9b03379, 8761-8764. doi: 10.1021/acs.orglett.9b03379

En route to D-ring inverted phorbol esters

2019

Journal Article

A novel long-range n to π* interaction secures the smallest known α-helix in water

Hoang, Huy N., Wu, Chongyang, Hill, Timothy A., Dantas de Araujo, Aline, Bernhardt, Paul V., Liu, Ligong and Fairlie, David P. (2019). A novel long-range n to π* interaction secures the smallest known α-helix in water. Angewandte Chemie International Edition, 58 (52) ange.201911277, 18873-18877. doi: 10.1002/anie.201911277

A novel long-range n to π* interaction secures the smallest known α-helix in water

2019

Journal Article

Proton-assisted air oxidation mechanisms of iron(ii) bis-thiosemicarbazone complexes at physiological pH: a kinetico-mechanistic study

Gonzálvez, Miguel A., Algarra, Andrés G., Basallote, Manuel G., Bernhardt, Paul V., Fernández-Trujillo, María J. and Martínez, Manuel (2019). Proton-assisted air oxidation mechanisms of iron(ii) bis-thiosemicarbazone complexes at physiological pH: a kinetico-mechanistic study. Dalton Transactions, 48 (44), 16578-16587. doi: 10.1039/c9dt03557e

Proton-assisted air oxidation mechanisms of iron(ii) bis-thiosemicarbazone complexes at physiological pH: a kinetico-mechanistic study

2019

Journal Article

Antibacterial 5α-spirostane saponins from the fruit of Cordyline manners-suttoniae

Tran, Trong D., Olsson, Malin A., Choudhury, Md Abu, McMillan, David J., Cullen, Jason K., Parsons, Peter G., Bernhardt, Paul V., Reddell, Paul W. and Ogbourne, Steven M. (2019). Antibacterial 5α-spirostane saponins from the fruit of Cordyline manners-suttoniae. Journal of Natural Products, 82 (10) acs.jnatprod.9b00502, 2809-2817. doi: 10.1021/acs.jnatprod.9b00502

Antibacterial 5α-spirostane saponins from the fruit of Cordyline manners-suttoniae

2019

Journal Article

Ascorbyl and hydroxyl radical generation mediated by a copper complex adsorbed on gold

Romo, Adolfo I. B., Dibo, Vitória S., Abreu, Dieric S., Carepo, Marta S. P., Neira, Andrea C., Castillo, Ivan, Lemus, Luis, Nascimento, Otaciro R., Bernhardt, Paul V., Sousa, Eduardo H. S. and Diógenes, Izaura C. N. (2019). Ascorbyl and hydroxyl radical generation mediated by a copper complex adsorbed on gold. Dalton Transactions, 48 (37), 14128-14137. doi: 10.1039/c9dt01726g

Ascorbyl and hydroxyl radical generation mediated by a copper complex adsorbed on gold

2019

Journal Article

Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon

Tan, Yuen P., Xue, Yongbo, Savchenko, Andrei I., Houston, Sevan D., Modhiran, Naphak, McMillan, Christopher L. D., Boyle, Glen M., Bernhardt, Paul V., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon. Journal of Natural Products, 82 (10) acs.jnatprod.9b00522, 2828-2834. doi: 10.1021/acs.jnatprod.9b00522

Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon

2019

Journal Article

Chrysosporazines A–E: P-glycoprotein inhibitory piperazines from an Australian marine fish gastrointestinal tract-derived fungus, Chrysosporium sp. CMB-F214

Elbanna, Ahmed H., Khalil, Zeinab G., Bernhardt, Paul V. and Capon, Robert J. (2019). Chrysosporazines A–E: P-glycoprotein inhibitory piperazines from an Australian marine fish gastrointestinal tract-derived fungus, Chrysosporium sp. CMB-F214. Organic Letters, 21 (19) acs.orglett.9b03094, 8097-8100. doi: 10.1021/acs.orglett.9b03094

Chrysosporazines A–E: P-glycoprotein inhibitory piperazines from an Australian marine fish gastrointestinal tract-derived fungus, Chrysosporium sp. CMB-F214

2019

Journal Article

Computer modelling and synthesis of deoxy and monohydroxy analogues of a ribitylaminouracil bacterial metabolite that potently activates human T cells

Ler, Geraldine J. M., Xu, Weijun, Mak, Jeffrey Y. W., Liu, Ligong, Bernhardt, Paul V. and Fairlie, David P (2019). Computer modelling and synthesis of deoxy and monohydroxy analogues of a ribitylaminouracil bacterial metabolite that potently activates human T cells. Chemistry – A European Journal, 25 (68) chem.201903732, 15594-15608. doi: 10.1002/chem.201903732

Computer modelling and synthesis of deoxy and monohydroxy analogues of a ribitylaminouracil bacterial metabolite that potently activates human T cells