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2020 Journal Article A chemoenzymatic approach to the synthesis of glycopeptide antibiotic analoguesTailhades, Julien, Zhao, Yongwei, Ho, Y. T. Candace, Greule, Anja, Ahmed, Iftekhar, Schoppet, Melanie, Kulkarni, Ketav, Goode, Rob J. A., Schittenhelm, Ralf B., De Voss, James J. and Cryle, Max J. (2020). A chemoenzymatic approach to the synthesis of glycopeptide antibiotic analogues. Angewandte Chemie, 132 (27), 10991-10995. doi: 10.1002/ange.202003726 |
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2020 Journal Article Oxygen surrogate systems for supporting human drug-metabolizing cytochrome P450 enzymesStrohmaier, Silja J., De Voss, James J., Jurva, Ulrik, Andersson, Shalini and Gillam, Elizabeth M. J. (2020). Oxygen surrogate systems for supporting human drug-metabolizing cytochrome P450 enzymes. Drug Metabolism and Disposition , 48 (6), 432-437. doi: 10.1124/dmd.120.090555 |
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2020 Journal Article A chemoenzymatic approach to the synthesis of glycopeptide antibiotic analoguesTailhades, Julien, Zhao, Yongwei, Ho, Y. T. Candace, Greule, Anja, Ahmed, Iftekhar, Schoppet, Melanie, Kulkarni, Ketav, Goode, Rob J. A., Schittenhelm, Ralf B., De Voss, James J. and Cryle, Max J. (2020). A chemoenzymatic approach to the synthesis of glycopeptide antibiotic analogues. Angewandte Chemie International Edition, 59 (27) anie.202003726, 10899-10903. doi: 10.1002/anie.202003726 |
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2020 Journal Article Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymesColeman, Tom, Stok, Jeanette E., Podgorski, Matthew N., Bruning, John B., De Voss, James J. and Bell, Stephen G. (2020). Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes. JBIC Journal of Biological Inorganic Chemistry, 25 (4), 583-596. doi: 10.1007/s00775-020-01781-4 |
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2020 Journal Article Biophysical techniques for distinguishing ligand binding modes in cytochrome P450 monooxygenasesPodgorski, Matthew N., Harbort, Joshua S., Coleman, Tom, Stok, Jeanette E., Yorke, Jake A., Wong, Luet-Lok, Bruning, John B., Bernhardt, Paul V., De Voss, James J., Harmer, Jeffrey R. and Bell, Stephen G. (2020). Biophysical techniques for distinguishing ligand binding modes in cytochrome P450 monooxygenases. Biochemistry, 59 (9) acs.biochem.0c00027, 1038-1050. doi: 10.1021/acs.biochem.0c00027 |
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2020 Journal Article An inexpensive, efficient alternative to NADPH to support catalysis by thermostable cytochrome P450 enzymesStrohmaier, Silja J., Baek, Jong Min, De Voss, James J., Jurva, Ulrik, Andersson, Shalini and Gillam, Elizabeth M. J. (2020). An inexpensive, efficient alternative to NADPH to support catalysis by thermostable cytochrome P450 enzymes. ChemCatChem, 12 (6) cctc.201902235, 1750-1761. doi: 10.1002/cctc.201902235 |
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2020 Journal Article Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactionsPodgorski, Matthew N., Coleman, Tom, Chao, Rebecca R., De Voss, James J., Bruning, John B. and Bell, Stephen G. (2020). Investigation of the requirements for efficient and selective cytochrome P450 monooxygenase catalysis across different reactions. Journal of Inorganic Biochemistry, 203 110913, 1-13. doi: 10.1016/j.jinorgbio.2019.110913 |
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2019 Journal Article Rearrangement-free hydroxylation of methylcubanes by a cytochrome P450: the case for dynamical coupling of C–H abstraction and reboundSarkar, Md. Raihan, Houston, Sevan D., Savage, G. Paul, Williams, Craig M., Krenske, Elizabeth H., Bell, Stephen G. and De Voss, James J. (2019). Rearrangement-free hydroxylation of methylcubanes by a cytochrome P450: the case for dynamical coupling of C–H abstraction and rebound. Journal of the American Chemical Society, 141 (50) jacs.9b08064, 19688-19699. doi: 10.1021/jacs.9b08064 |
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2019 Journal Article Exploring the substrate specificity of cytochrome P450cinStok, Jeanette E., Giang, Peter D., Wong, Siew Hoon and De Voss, James J. (2019). Exploring the substrate specificity of cytochrome P450cin. Archives of Biochemistry and Biophysics, 672 108060, 108060. doi: 10.1016/j.abb.2019.07.025 |
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2019 Journal Article The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complementHouston, Sevan D., Fahrenhorst-Jones, Tyler, Xing, Hui, Chalmers, Benjamin A., Sykes, Melissa L., Stok, Jeanette E., Farfan Soto, Clementina, Burns, Jed M., Bernhardt, Paul V., De Voss, James J., Boyle, Glen M., Smith, Maree T., Tsanaktsidis, John, Savage, G. Paul, Avery, Vicky M. and Williams, Craig M. (2019). The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement. Organic and Biomolecular Chemistry, 17 (28), 6790-6798. doi: 10.1039/c9ob01238a |
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2019 Journal Article Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibioticsGreule, Anja, Izoré, Thierry, Iftime, Dumitrita, Tailhades, Julien, Schoppet, Melanie, Zhao, Yongwei, Peschke, Madeleine, Ahmed, Iftekhar, Kulik, Andreas, Adamek, Martina, Goode, Robert J. A., Schittenhelm, Ralf B., Kaczmarski, Joe A., Jackson, Colin J., Ziemert, Nadine, Krenske, Elizabeth H., De Voss, James J., Stegmann, Evi and Cryle, Max J. (2019). Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics. Nature Communications, 10 (1) 2613, 2613. doi: 10.1038/s41467-019-10384-w |
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2019 Journal Article Pyrrolizidine alkaloids of Blue Heliotrope (Heliotropium amplexicaule) and their presence in Australian honeyCarpinelli de Jesus, Matheus, Hungerford, Natasha L., Carter, Steve J., Anuj, Shalona R., Blanchfield, Joanne T., De Voss, James Joseph and Fletcher, Mary T. (2019). Pyrrolizidine alkaloids of Blue Heliotrope (Heliotropium amplexicaule) and their presence in Australian honey. Journal of Agricultural and Food Chemistry, 67 (28) acs.jafc.9b02136, 7995-8006. doi: 10.1021/acs.jafc.9b02136 |
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2019 Journal Article Caco-2 monolayer permeability and stability of Chamaelirium luteum (false unicorn) open-chain steroidal saponinsStockdale, Tegan P., Challinor, Victoria L., Lehmann, Reginald P., De Voss, James J. and Blanchfield, Joanne T. (2019). Caco-2 monolayer permeability and stability of Chamaelirium luteum (false unicorn) open-chain steroidal saponins. ACS Omega, 4 (4), 7658-7666. doi: 10.1021/acsomega.9b00496 |
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2019 Journal Article Significance of protein-substrate hydrogen bonding for the selectivity of P450-catalysed oxidationsSlessor, Kate E., Stok, Jeanette E., Chow, Sharon and De Voss, James J. (2019). Significance of protein-substrate hydrogen bonding for the selectivity of P450-catalysed oxidations. Chemistry: A European Journal, 25 (16), 4149-4155. doi: 10.1002/chem.201805705 |
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2019 Journal Article Selective hydroxylation of 1,8- and 1,4-cineole using bacterial P450 variantsLee, Joel H.Z., Wong, Siew Hoon, Stok, Jeanette E., Bagster, Sarah A., Beckett, James, Clegg, Jack K., Brock, Aidan, De Voss, James J. and Bell, Stephen G. (2019). Selective hydroxylation of 1,8- and 1,4-cineole using bacterial P450 variants. Archives of Biochemistry and Biophysics, 663, 54-63. doi: 10.1016/j.abb.2018.12.025 |
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2019 Journal Article Cyclooctatetraene: a bioactive cubane paradigm complementXing, Hui, Houston, Sevan D., Chen, Xuejie, Ghassabian, Sussan, Fahrenhorst-Jones, Tyler, Kuo, Andy, Murray, Cody-Ellen P., Conn, Kyna-Anne, Jaeschke, Kara N., Jin, Da-Yun, Pasay, Cielo, Bernhardt, Paul V., Burns, Jed M., Tsanaktsidis, John, Savage, G. Paul, Boyle, Glen M., De Voss, James J., McCarthy, James, Walter, Gimme H., Burne, Thomas H. J., Smith, Maree T., Tie, Jian-Ke and Williams, Craig M. (2019). Cyclooctatetraene: a bioactive cubane paradigm complement. Chemistry: A European Journal, 25 (11), 2729-2734. doi: 10.1002/chem.201806277 |
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2019 Journal Article Engineering thermostable CYP2D enzymes for biocatalysis using combinatorial libraries of ancestors for directed evolution (CLADE)Gumulya, Yosephine, Huang, Weiliang, D'Cunha, Stephlina A., Richards, Katelyn E., Thomson, Raine E.S., Hunter, Dominic J.B., Baek, Jong-Min, Harris, Kurt L., Boden, Mikael, De Voss, James J., Hayes, Martin A., Isin, Emre M., Andersson, Shalini, Jurva, Ulrik and Gillam, Elizabeth (2019). Engineering thermostable CYP2D enzymes for biocatalysis using combinatorial libraries of ancestors for directed evolution (CLADE). ChemCatChem, 11 (2) cctc.201801644, 841-850. doi: 10.1002/cctc.201801644 |
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2019 Journal Article Enzymatic cascade to evaluate the tricyclization of glycopeptide antibiotic precursor peptides as a prequel to biosynthetic redesignTailhades, Julien, Zhao, Yongwei, Schoppet, Melanie, Greule, Anja, Goode, Robert J. A., Schittenhelm, Ralf B., De Voss, James J. and Cryle, Max J. (2019). Enzymatic cascade to evaluate the tricyclization of glycopeptide antibiotic precursor peptides as a prequel to biosynthetic redesign. Organic Letters, 21 (21) acs.orglett.9b03245, 8635-8640. doi: 10.1021/acs.orglett.9b03245 |
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2018 Journal Article Engineering highly functional thermostable proteins using ancestral sequence reconstructionGumulya, Yosephin, Baek, Jong-Min, Wun, Shun-Jie, Thomson, Raine E. S., Harris, Kurt L., Hunter, Dominic J. B., Behrendorff, James B. Y. H., Kulig, Justyna, Zheng, Shan, Wu, Xueming, Wu, Bin, Stok, Jeanette E., De Voss, James J., Schenk, Gerhard, Jurva, Ulrik, Andersson, Shalini, Isin, Emre M., Bodén, Mikael, Guddat, Luke and Gillam, Elizabeth M. J. (2018). Engineering highly functional thermostable proteins using ancestral sequence reconstruction. Nature Catalysis, 1 (11), 878-888. doi: 10.1038/s41929-018-0159-5 |
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2018 Journal Article Corrigendum to: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere (Angewandte Chemie International Edition, (2016), 55, 11, (3580-3585), 10.1002/anie.201510675)Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2018). Corrigendum to: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere (Angewandte Chemie International Edition, (2016), 55, 11, (3580-3585), 10.1002/anie.201510675). Angewandte Chemie - International Edition, 57 (28), 8359-8359. doi: 10.1002/anie.201711161 |
